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58 / 12,170 descriptions found* Show info (disease name, etc.) on mouse-over.
 No.   Drug (Description in trials)   DrugBank   KEGG DRUG  KEGG GENES
 [Number of genes] 
 KEGG PATHWAY 
 [Number of pathways] 
 Disease ID
 [Number of diseases] 
 1   11c-flumazenil   Flumazenil   D00697   [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction   [1]
206 
 2   [18f]fpeb   -   -   -   -   [3]
6,
8,
206 
 3   [18f]fpeb pet imaging   -   -   -   -   [1]
206 
 4   Acamprosate   Acamprosate   D02780, D07058   [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   [17] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Rap1 signaling pathway, Ras signaling pathway, Systemic lupus erythematosus, cAMP signaling pathway   [2]
6,
206 
 5   Acetate   Acetate   -   -   -   [40]
1,
2,
6,
10,
13,
35,
40,
46,
49,
51,
60,
64,
70,
71,
73,
75,
76,
78,
81,
83,
85,
86,
88,
90,
96,
97,
113,
145,
156,
162,
171,
206,
222,
224,
225,
235,
265,
288,
298,
299 
 6   Acidum ascorbicum   Ascorbic acid   D00018   -   -   [1]
206 
 7   Acidum ascorbicum d6   Ascorbic acid   D00018   -   -   [1]
206 
 8   Af056   -   -   -   -   [1]
206 
 9   Afq056   -   -   -   -   [3]
6,
8,
206 
 10   Arbaclofen   Arbaclofen   D09791   [2] GABBR1, GABBR2   [7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway   [2]
13,
206 
 11   Aripiprazole   Aripiprazole   D01164   [4] DRD2, DRD3, HTR1A, HTR2A   [12] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway   [2]
6,
206 
 12   Azd7325   Azd7325   -   -   -   [1]
206 
 13   Azd7325 (high-dose)   Azd7325   -   -   -   [1]
206 
 14   Azd7325 (low-dose)   Azd7325   -   -   -   [1]
206 
 15   Bpn14770   Bpn14770   -   -   -   [1]
206 
 16   Cx516   Cx516   -   -   -   [1]
206 
 17   Cx516 (ampalex®)   Cx516   -   -   -   [1]
206 
 18   Donepezil   Donepezil   D00670, D07869   [1] ACHE   [2] Cholinergic synapse, Glycerophospholipid metabolism   [9]
5,
6,
13,
46,
78,
124,
127,
156,
206 
 19   Egcg   Epigallocatechin gallate   -   -   -   [8]
6,
13,
17,
28,
85,
113,
206,
299 
 20   Egcg fontup   Epigallocatechin gallate   -   -   -   [1]
206 
 21   Flumazenil   Flumazenil   D00697   [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction   [5]
6,
13,
17,
18,
206 
 22   Fluoxetin   Fluoxetine   D00326, D00823   [1] SLC6A4   [2] Serotonergic synapse, Synaptic vesicle cycle   [3]
13,
179,
206 
 23   Gaboxadol   Gaboxadol   D04282   [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction   [2]
201,
206 
 24   Ganaxolone   Ganaxolone   D04300   [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction   [3]
145,
152,
206 
 25   Lovastatin   Lovastatin   D00359   [1] HMGCR   [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis   [10]
6,
34,
46,
79,
156,
160,
195,
206,
263,
310 
 26   Lovastatin, then minocycline/lovastatin   Minocycline   D00850, D05045   -   -   [1]
206 
 27   Mavoglurant   Mavoglurant   -   -   -   [1]
206 
 28   Metformin   Metformin   D00944, D04966   [2] PRKAA1, PRKAA2   [19] AMPK signaling pathway, Adipocytokine signaling pathway, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy (HCM), Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease (NAFLD), Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway   [16]
6,
13,
46,
49,
67,
75,
77,
81,
86,
113,
158,
206,
225,
233,
265,
285 
 29   Methylphenidate   Methylphenidate   D01296, D04999   [2] SLC6A2, SLC6A3   [6] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Synaptic vesicle cycle   [7]
6,
13,
34,
84,
113,
179,
206 
 30   Methylphenidate, fluoxetin, risperidone   Methylphenidate   D01296, D04999   [2] SLC6A2, SLC6A3   [6] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Synaptic vesicle cycle   [2]
179,
206 
 31   Mg01ci extended-release tablet   -   -   -   -   [1]
206 
 32   Mglu5 antagonist   -   -   -   -   [1]
206 
 33   Minocycline   Minocycline   D00850, D05045   -   -   [13]
2,
6,
8,
13,
46,
85,
90,
94,
162,
201,
206,
280,
299 
 34   Minocycline hydrochloride   Minocycline   D00850, D05045   -   -   [4]
13,
201,
206,
299 
 35   Minocycline, then minocycline/lovastatin   Minocycline   D00850, D05045   -   -   [1]
206 
 36   Nnz-2566   -   -   -   -   [2]
156,
206 
 37   Npl-2009   -   -   -   -   [1]
206 
 38   Ov101   -   -   -   -   [2]
201,
206 
 39   Ov101 (gaboxadol)   Gaboxadol   D04282   [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   [7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction   [1]
206 
 40   Oxytocin   Oxytocin   D00089   [1] OXTR   [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway   [4]
127,
193,
206,
226 
 41   Oxytocin 24iu   Oxytocin   D00089   [1] OXTR   [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway   [1]
206 
 42   Oxytocin 48iu   Oxytocin   D00089   [1] OXTR   [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway   [1]
206 
 43   Riluzole   Riluzole   D00775   [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   [20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway   [7]
2,
3,
5,
8,
13,
17,
206 
 44   Risperidone   Risperidone   D00426   [2] DRD2, HTR2A   [11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway   [5]
8,
156,
179,
187,
206 
 45   Ro 491-7523/f18   -   -   -   -   [1]
206 
 46   Ro 491-7523/f19   -   -   -   -   [1]
206 
 47   Ro4917523   -   -   -   -   [1]
206 
 48   Ro4917523 0.5 mg   -   -   -   -   [1]
206 
 49   Ro4917523 1.5 mg   -   -   -   -   [1]
206 
 50   Sertraline   Sertraline   D00825, D02360   [1] SLC6A4   [2] Serotonergic synapse, Synaptic vesicle cycle   [2]
6,
206 
 51   Stx107   -   -   -   -   [1]
206 
 52   Stx209   -   -   -   -   [1]
206 
 53   Sugar pill   -   -   -   -   [7]
6,
49,
67,
70,
86,
206,
226 
 54   Tocopheryl acetate   Acetate   -   -   -   [1]
206 
 55   Vitamin c   Ascorbic acid   D00018   -   -   [5]
10,
192,
206,
211,
212 
 56   Vitamin c 10mg/kg vitamin e 10 mg/kg   Vitamin e   D02331   -   -   [1]
206 
 57   Vitamin e   Vitamin e   D02331   -   -   [11]
2,
6,
13,
20,
46,
90,
96,
97,
206,
299,
317 
 58   Zyn002 - cbd transdermal gel   -   -   -   -   [1]
206 

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