No. |
Drug (Description in trials) |
DrugBank |
KEGG DRUG * |
KEGG GENES * [Number of genes] |
KEGG PATHWAY [Number of pathways] |
Disease ID * [Number of diseases] |
1 |
Ach-0144471 |
- |
- |
- |
- |
[3] 62, 222, 223 |
2 |
Apl-2 |
- |
- |
- |
- |
[5] 61, 62, 66, 222, 223 |
3 |
Avacopan |
Avacopan |
D11093 |
[1] C5AR1 |
[3] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection |
[4] 43, 44, 222, 223 |
4 |
Ccx168 |
- |
- |
- |
- |
[6] 43, 44, 66, 109, 222, 223 |
5 |
Cdx-1135 |
- |
- |
- |
- |
[2] 222, 223 |
6 |
Cyclosporin |
Ciclosporin |
D00184 |
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
[30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway |
[16] 14, 38, 39, 49, 53, 56, 60, 62, 63, 97, 113, 164, 222, 223, 274, 326 |
7 |
Eculizumab |
Eculizumab |
D03940 |
[1] C5 |
[7] Complement and coagulation cascades, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Pertussis, Prion diseases, Staphylococcus aureus infection, Systemic lupus erythematosus |
[7] 11, 13, 14, 62, 109, 222, 223 |
8 |
Oms721 |
- |
- |
- |
- |
[5] 64, 66, 109, 222, 223 |
9 |
Rituximab |
Rituximab |
D02994 |
[1] MS4A1 |
[1] Hematopoietic cell lineage |
[42] 11, 13, 14, 17, 35, 36, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 223, 229, 256, 271, 283, 284, 285, 288, 300, 331 |
10 |
Soliris |
Eculizumab |
D03940 |
[1] C5 |
[7] Complement and coagulation cascades, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Pertussis, Prion diseases, Staphylococcus aureus infection, Systemic lupus erythematosus |
[7] 11, 13, 14, 62, 109, 222, 223 |
11 |
Sulodexide |
Sulodexide |
D08547 |
[2] SERPINC1, SERPIND1 |
[1] Complement and coagulation cascades |
[1] 223 |
12 |
Tp10 |
- |
- |
- |
- |
[1] 223 |