No. |
Drug (Description in trials) |
DrugBank |
KEGG DRUG * |
KEGG GENES * [Number of genes] |
KEGG PATHWAY [Number of pathways] |
Disease ID * [Number of diseases] |
1 |
4-pba |
- |
- |
- |
- |
[1] 231 |
2 |
Acetaminophen |
Acetaminophen |
D00217 |
[2] PTGS1, PTGS2 |
[21] Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway |
[11] 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
3 |
Aerosolized human alpha-1 antitrypsin |
- |
- |
- |
- |
[1] 231 |
4 |
Albumin (human) 20%, united states pharmacopeia (usp) |
- |
- |
- |
- |
[1] 231 |
5 |
Albuterol |
Salbutamol |
D02147 |
[1] ADRB2 |
[8] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway |
[8] 12, 13, 86, 89, 113, 231, 256, 299 |
6 |
Albuterol inhaler. |
Salbutamol |
D02147 |
[1] ADRB2 |
[8] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway |
[2] 231, 299 |
7 |
Aln-61444 |
- |
- |
- |
- |
[1] 231 |
8 |
Aln-aat |
- |
- |
- |
- |
[1] 231 |
9 |
Aln-aat02 |
- |
- |
- |
- |
[1] 231 |
10 |
Alpha 1-proteinase inhibitor |
Alpha-1-proteinase inhibitor |
- |
- |
- |
[1] 231 |
11 |
Alpha 1-proteinase inhibitor (human) |
Alpha-1-proteinase inhibitor |
- |
- |
- |
[1] 231 |
12 |
Alpha-1 antitrypsin (human) |
- |
- |
- |
- |
[1] 231 |
13 |
Alpha-1 mp |
- |
- |
- |
- |
[1] 231 |
14 |
Alpha-1 proteinase inhibitor (human) |
- |
- |
- |
- |
[1] 231 |
15 |
Alpha-1-antitrypsin |
Alpha-1-proteinase inhibitor |
- |
- |
- |
[1] 231 |
16 |
Alpha1-proteinase inhibitor |
Alpha-1-proteinase inhibitor |
- |
- |
- |
[2] 231, 299 |
17 |
Alpha1-proteinase inhibitor (human) |
Alpha-1-proteinase inhibitor |
- |
- |
- |
[2] 231, 299 |
18 |
Alvelestat |
Alvelestat |
- |
- |
- |
[1] 231 |
19 |
Alvelestat (mph996) |
Alvelestat |
- |
- |
- |
[1] 231 |
20 |
Alvelestat oral tablet - dose 1 |
Alvelestat |
- |
- |
- |
[1] 231 |
21 |
Alvelestat oral tablet - dose 2 |
Alvelestat |
- |
- |
- |
[1] 231 |
22 |
Api-aat |
- |
- |
- |
- |
[1] 231 |
23 |
Api-aat, ad00370, arc-aat, api drug substance |
- |
- |
- |
- |
[1] 231 |
24 |
Arc-aat |
- |
- |
- |
- |
[1] 231 |
25 |
Arc-aat injection |
- |
- |
- |
- |
[1] 231 |
26 |
Aro-aat injection |
- |
- |
- |
- |
[1] 231 |
27 |
Aspirin |
Acetylsalicylic acid |
D00109 |
[2] PTGS1, PTGS2 |
[21] Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway |
[10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
28 |
Carbamazepine |
Carbamazepine |
D00252 |
[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A |
[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction |
[1] 231 |
29 |
Dose of 60 mg/kg alpha1-proteinase inhibitor |
Alpha-1-proteinase inhibitor |
- |
- |
- |
[1] 231 |
30 |
Dose of 60 mg/kg fraction iv-1 alpha1-proteinase inhibitor |
Alpha-1-proteinase inhibitor |
- |
- |
- |
[1] 231 |
31 |
Drug-carbamazepine (tegretol xr) |
Carbamazepine |
D00252 |
[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A |
[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction |
[1] 231 |
32 |
Fentanyl |
Fentanyl |
D00320, D01399 |
[1] OPRM1 |
[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction |
[5] 46, 70, 85, 215, 231 |
33 |
Glassia |
Alpha-1-proteinase inhibitor |
- |
- |
- |
[1] 231 |
34 |
Hyaluronic acid |
Hyaluronic acid |
D08043 |
- |
- |
[5] 46, 53, 70, 226, 231 |
35 |
Hyaluronic acid inhalation solution |
Hyaluronic acid |
D08043 |
- |
- |
[1] 231 |
36 |
Inbrx-101/rhaat-fc |
- |
- |
- |
- |
[1] 231 |
37 |
Kamada-api |
- |
- |
- |
- |
[1] 231 |
38 |
Kamada-api for inhalation, 160mg |
- |
- |
- |
- |
[1] 231 |
39 |
Kamada-api for inhalation, 80mg |
- |
- |
- |
- |
[1] 231 |
40 |
Lidocaine |
Lidocaine |
D00358, D02086, D08127 |
[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A |
[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction |
[8] 6, 13, 46, 86, 168, 226, 231, 256 |
41 |
Lorazepam |
Lorazepam |
D00365 |
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction |
[1] 231 |
42 |
Midazolam |
Midazolam |
D00550, D00696, D05028 |
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction |
[10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
43 |
None assigned |
- |
- |
- |
- |
[2] 231, 299 |
44 |
Octaalpha1 |
- |
- |
- |
- |
[1] 231 |
45 |
Ondansetron |
Ondansetron |
D00456, D00678 |
[5] HTR3A, HTR3B, HTR3C, HTR3D, HTR3E |
[2] Serotonergic synapse, Taste transduction |
[1] 231 |
46 |
Oxycodone |
Oxycodone |
D03783, D05312, D05462 |
[3] OPRD1, OPRK1, OPRM1 |
[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway |
[7] 6, 13, 46, 70, 226, 231, 298 |
47 |
Oxycodone/acetaminophen |
Acetaminophen |
D00217 |
[2] PTGS1, PTGS2 |
[21] Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway |
[1] 231 |
48 |
Prolastin |
- |
- |
- |
- |
[1] 231 |
49 |
Prolastin-c |
Alpha-1-proteinase inhibitor |
- |
- |
- |
[2] 231, 298 |
50 |
Prolastin-c, 120 mg/kg |
- |
- |
- |
- |
[1] 231 |
51 |
Prolastin-c, 60 mg/kg |
- |
- |
- |
- |
[1] 231 |
52 |
Raav1-cb-haat |
- |
- |
- |
- |
[1] 231 |
53 |
Retinoic acid |
Tretinoin |
D00094 |
[3] PML, RARA, RARB |
[12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis |
[2] 94, 231 |
54 |
Retinoic acid receptor gamma agonist |
Tretinoin |
D00094 |
[3] PML, RARA, RARB |
[12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis |
[1] 231 |
55 |
Ro3300074 |
- |
- |
- |
- |
[1] 231 |
56 |
Xenon |
Xenon |
D01901, D06339 |
- |
- |
[5] 22, 85, 228, 231, 299 |