No. |
Drug (Description in trials) |
DrugBank |
KEGG DRUG * |
KEGG GENES * [Number of genes] |
KEGG PATHWAY [Number of pathways] |
Disease ID * [Number of diseases] |
1 |
Aln-65585 |
- |
- |
- |
- |
[1] 234 |
2 |
Aln-go1 |
- |
- |
- |
- |
[1] 234 |
3 |
Cald hr-d (high-risk, regimen c) |
- |
- |
- |
- |
[4] 19, 20, 234, 326 |
4 |
Cald hr-d (high-risk, regimen d) |
- |
- |
- |
- |
[4] 19, 20, 234, 326 |
5 |
Cald sr-a (standard-risk, regimen a) |
- |
- |
- |
- |
[4] 19, 20, 234, 326 |
6 |
Cald sr-b (standard-risk, regimen b) |
- |
- |
- |
- |
[4] 19, 20, 234, 326 |
7 |
Campath-1h |
Alemtuzumab |
D02802 |
- |
- |
[6] 19, 20, 60, 234, 285, 326 |
8 |
Chenodeoxycholic acid |
Chenodeoxycholic acid |
D00163 |
[1] NR1H4 |
[1] Bile secretion |
[4] 20, 96, 234, 263 |
9 |
Cholic acid |
Cholic acid |
D10699 |
[1] NR1H4 |
[1] Bile secretion |
[4] 20, 234, 265, 310 |
10 |
Cholic acids |
- |
- |
- |
- |
[2] 20, 234 |
11 |
Clofarabine |
Clofarabine |
D03546 |
[3] POLA1, POLA2, RRM1 |
[6] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism |
[9] 19, 20, 40, 46, 49, 60, 96, 234, 326 |
12 |
Cyclosporine |
Ciclosporin |
D00184 |
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
[30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway |
[33] 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 62, 64, 65, 90, 95, 97, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302 |
13 |
Cyclosporine a |
Ciclosporin |
D00184 |
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
[30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway |
[8] 19, 20, 36, 49, 53, 58, 60, 234 |
14 |
Dcr-1171x |
- |
- |
- |
- |
[1] 234 |
15 |
Dcr-ph1 |
- |
- |
- |
- |
[1] 234 |
16 |
Dcr-phxc |
- |
- |
- |
- |
[1] 234 |
17 |
Hematopoietic stem cell transplantation |
- |
- |
- |
- |
[12] 11, 13, 14, 19, 20, 35, 46, 49, 51, 96, 234, 285 |
18 |
Hydroxychloroquine |
Hydroxychloroquine |
D08050 |
- |
- |
[18] 13, 41, 46, 48, 49, 53, 56, 66, 84, 89, 90, 96, 222, 234, 254, 271, 298, 299 |
19 |
Imd preparative regimen |
- |
- |
- |
- |
[4] 19, 20, 234, 326 |
20 |
Lumasiran |
- |
- |
- |
- |
[1] 234 |
21 |
Melphalan |
Melphalan |
D00369 |
- |
- |
[14] 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285 |
22 |
Mycophenolate |
Mycophenolic acid |
D05096 |
[2] IMPDH1, IMPDH2 |
[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism |
[33] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 |
23 |
Mycophenolate mofetil |
Mycophenolate mofetil |
D00752, D05094, D05095 |
[2] IMPDH1, IMPDH2 |
[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism |
[32] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 |
24 |
Osteopetrosis haploidentical only preparative regimen |
- |
- |
- |
- |
[4] 19, 20, 234, 326 |
25 |
Osteopetrosis only preparative regimen |
- |
- |
- |
- |
[4] 19, 20, 234, 326 |
26 |
Stem cell transplantation |
- |
- |
- |
- |
[9] 13, 19, 20, 46, 65, 90, 164, 234, 326 |
27 |
Sterile normal saline (0.9% nacl) |
- |
- |
- |
- |
[3] 62, 234, 254 |
28 |
Ursodiol |
Ursodeoxycholic acid |
D00734 |
[1] NR1H4 |
[1] Bile secretion |
[6] 8, 20, 93, 97, 234, 299 |