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   e.g. "Sirolimus", "Adalimumab"

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70 / 12,170 descriptions found* Show info (disease name, etc.) on mouse-over.
 No.   Drug (Description in trials)   DrugBank   KEGG DRUG  KEGG GENES
 [Number of genes] 
 KEGG PATHWAY 
 [Number of pathways] 
 Disease ID
 [Number of diseases] 
 1   1-(2,3,4-trimethoxybenzyl)piperazine dihydrochloride   Piperazine   D00807, D01393, D02127, D02145, D05486, D06224   -   -   [1]
58 
 2   Acetylcysteine   Acetylcysteine   D00221   -   -   [14]
6,
13,
19,
20,
49,
51,
58,
85,
94,
111,
164,
233,
298,
299 
 3   Adenosine   Adenosine   D00045   [4] ADORA1, ADORA2A, ADORA2B, ADORA3   [12] Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [3]
13,
58,
65 
 4   Alcohol   Ethanol   D00068, D02798, D04855, D06542   -   -   [4]
13,
58,
279,
298 
 5   Antiarrhythmic drugs   -   -   -   -   [1]
58 
 6   Atorvastatin   Atorvastatin   D00258, D00887, D07474   [1] HMGCR   [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis   [17]
13,
46,
49,
51,
58,
63,
79,
84,
88,
93,
96,
160,
222,
225,
265,
271,
299 
 7   Bluefish   Bluefish   -   -   -   [1]
58 
 8   Bnp blood sample test   -   -   -   -   [1]
58 
 9   Candesartan   Candesartan   D00522   [1] AGTR1   [14] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [2]
58,
67 
 10   Carnitine   Levocarnitine   D02030, D02176, D04713   -   -   [8]
5,
13,
58,
96,
97,
265,
298,
316 
 11   Cas name: 1,4-benzoxazepin-5(2h)-one, 3,4-dihydro-4-(2-pyrimidinylmethyl)-7-[4- (trifluoromethoxy)phenyl] iupac name: 4-(pyrimidin-2-ylmethyl)-7-[4- (trifluoromethoxy)phenyl]-3,4-dihydro-1,4-benzoxazepin-5(2h)-one   -   -   -   -   [1]
58 
 12   Cas name: 1,4-benzoxazepin-5(2h)-one, 3,4-dihydro-4-(2-pyrimidinylmethyl)-7-[4-(trifluoromethoxy)phenyl] iupac name: 4-(pyrimidin-2-ylmethyl)-7-[4-(trifluoromethoxy)phenyl]-3,4-dihydro-1,4-benzoxazepin-5(2h)-one   -   -   -   -   [1]
58 
 13   Ck-3773274   -   -   -   -   [1]
58 
 14   Cyclosporine   Ciclosporin   D00184   [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   [30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway   [33]
11,
14,
19,
20,
28,
36,
40,
41,
42,
45,
46,
49,
50,
53,
56,
58,
60,
62,
64,
65,
90,
95,
97,
162,
164,
222,
226,
228,
234,
283,
284,
285,
302 
 15   Cyclosporine a   Ciclosporin   D00184   [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   [30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway   [8]
19,
20,
36,
49,
53,
58,
60,
234 
 16   Diltiazem   Diltiazem   D00616, D03830, D07845   [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   [34] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy (DCM), Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy (HCM), Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [3]
58,
86,
130 
 17   Diovan   Valsartan   D00400   [1] AGTR1   [14] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [1]
58 
 18   Diovan 160 mg   Valsartan   D00400   [1] AGTR1   [14] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [1]
58 
 19   Diovan 40 mg   Valsartan   D00400   [1] AGTR1   [14] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [1]
58 
 20   Diovan 80 mg   Valsartan   D00400   [1] AGTR1   [14] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [1]
58 
 21   Dobutamine   Dobutamine   D00632, D03879, D03880, D03881   [1] ADRB1   [10] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy (DCM), Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway   [3]
57,
58,
215 
 22   Echo and myocardial contrast echocardiography perfusion imaging   -   -   -   -   [1]
58 
 23   Endothelial function biomarkers   -   -   -   -   [1]
58 
 24   Gadolinium   Gadolinium   -   -   -   [6]
13,
34,
46,
58,
65,
305 
 25   Gs-6615 3 mg pink   -   -   -   -   [1]
58 
 26   Gs-6615 3 mg white   -   -   -   -   [1]
58 
 27   Gs-6615 6 mg white   -   -   -   -   [1]
58 
 28   Gutron   Midodrine   D01307, D08220   [3] ADRA1A, ADRA1B, ADRA1D   [7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [1]
58 
 29   Gutron 2,5mg   Midodrine   D01307, D08220   [3] ADRA1A, ADRA1B, ADRA1D   [7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [1]
58 
 30   Gutron 5mg   Midodrine   D01307, D08220   [3] ADRA1A, ADRA1B, ADRA1D   [7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [1]
58 
 31   Hyperpolarized 13c-pyruvate   Pyruvic acid   -   -   -   [1]
58 
 32   Losartan   Losartan   D00357, D08146   [1] AGTR1   [14] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [18]
13,
17,
19,
46,
58,
66,
67,
85,
96,
97,
98,
113,
164,
167,
179,
215,
222,
299 
 33   Losartan bluefish 50 mg   Bluefish, Losartan   D00357, D08146   [1] AGTR1   [14] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [1]
58 
 34   Mangafodipir   Mangafodipir   D08262   -   -   [2]
13,
58 
 35   Mavacamten   Mavacamten   -   -   -   [1]
58 
 36   Mek162   -   -   -   -   [2]
58,
195 
 37   Metoprolol   Metoprolol   D00601, D02358, D05011   [1] ADRB1   [10] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy (DCM), Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway   [6]
17,
57,
58,
113,
193,
226 
 38   Metoprolol succinate   Metoprolol   D00601, D02358, D05011   [1] ADRB1   [10] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy (DCM), Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway   [4]
57,
58,
113,
193 
 39   Midodrine   Midodrine   D01307, D08220   [3] ADRA1A, ADRA1B, ADRA1D   [7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [3]
6,
17,
58 
 40   Midodrine hydrochloride   Midodrine   D01307, D08220   [3] ADRA1A, ADRA1B, ADRA1D   [7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [1]
58 
 41   Monitor   Methamidophos   -   -   -   [12]
2,
11,
13,
19,
46,
49,
58,
70,
85,
98,
298,
300 
 42   Myk-461   -   -   -   -   [1]
58 
 43   N-acetylcysteine   Acetylcysteine   D00221   -   -   [10]
6,
13,
19,
20,
49,
58,
85,
111,
164,
299 
 44   Nitrate   Nitrate   D02313   -   -   [3]
58,
113,
299 
 45   Perhexiline   Perhexiline   D05442, D08340   [8] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CPT1A, CPT1B, CPT1C, CPT2   [42] AMPK signaling pathway, Adipocytokine signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy (DCM), Dopaminergic synapse, Fatty acid degradation, Fatty acid metabolism, GABAergic synapse, Glucagon signaling pathway, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy (HCM), Insulin resistance, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, PPAR signaling pathway, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Thermogenesis, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [2]
58,
272 
 46   Perxexiline   -   -   -   -   [1]
58 
 47   Pexsig   -   -   -   -   [1]
58 
 48   Piperazine   Piperazine   D00807, D01393, D02127, D02145, D05486, D06224   -   -   [1]
58 
 49   Pirfenidone   Pirfenidone   D01583   [6] CCL2, IL10, IL1A, IL1B, IL6, TNF   [80] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease (American trypanosomiasis), Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy (DCM), EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pertussis, Prion diseases, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [10]
34,
46,
50,
51,
58,
84,
85,
164,
222,
228 
 50   Pyruvate   Pyruvic acid   -   -   -   [2]
58,
299 
 51   Ranexa   Ranolazine   D05700, D05701   -   -   [1]
58 
 52   Ranolazine   Ranolazine   D05700, D05701   -   -   [6]
2,
58,
86,
113,
114,
130 
 53   Ranolazine 1000 mg pr tablets   Ranolazine   D05700, D05701   -   -   [1]
58 
 54   Ranolazine 500 mg pr tablets   Ranolazine   D05700, D05701   -   -   [1]
58 
 55   Ranolazine 750 mg pr tablets   Ranolazine   D05700, D05701   -   -   [1]
58 
 56   Ranolazine pr (prolonged-release) 500 mg 1 tablet bis in die and 750 mg 1 tablet bis in die   Ranolazine   D05700, D05701   -   -   [1]
58 
 57   Regadenoson   Regadenoson   D05711   [1] ADORA2A   [7] Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway   [1]
58 
 58   Sacubitril   Sacubitril   D10225   [1] MME   [4] Alzheimer disease, Hematopoietic cell lineage, Protein digestion and absorption, Renin-angiotensin system   [1]
58 
 59   Sacubitril/valsartan   Sacubitril   D10225   [1] MME   [4] Alzheimer disease, Hematopoietic cell lineage, Protein digestion and absorption, Renin-angiotensin system   [1]
58 
 60   Sodium nitrate   Nitrate   D02313   -   -   [2]
58,
113 
 61   Spironolactone   Spironolactone   D00443   [1] NR3C2   [1] Aldosterone-regulated sodium reabsorption   [6]
58,
67,
86,
113,
218,
225 
 62   Treatment bx1514m   -   -   -   -   [1]
58 
 63   Trientine   Triethylenetetramine   -   -   -   [2]
58,
171 
 64   Trientine dihydrochloride   Triethylenetetramine   -   -   -   [2]
58,
171 
 65   Trimetazidine   Trimetazidine   D01606, D08642   -   -   [2]
58,
86 
 66   Trimetazidine dihydrochloride   Trimetazidine   D01606, D08642   -   -   [1]
58 
 67   Trimetazidine dihydrochloride 20mg   Trimetazidine   D01606, D08642   -   -   [1]
58 
 68   Valsartan   Valsartan   D00400   [1] AGTR1   [14] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [6]
57,
58,
66,
75,
218,
222 
 69   Vastarel   Trimetazidine   D01606, D08642   -   -   [1]
58 
 70   Vastarel 20mg film coated tablets   Trimetazidine   D01606, D08642   -   -   [1]
58 

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