No. |
DrugBank |
Drug (Description in trials) [Number of descriptions] |
KEGG DRUG * | KEGG GENES * [Number of genes] |
KEGG PATHWAY [Number of pathways] |
Disease ID * [Number of diseases] |
1 | Amantadine | [10] 240mg amantadine hcl er tablets; 320mg amantadine hcl er tablets; Ads-5102 (extended release amantadine hcl); Amantadine; Amantadine 300 mg; Amantadine hcl er; Amantadine hcl extended release; Amantadine hydrochloride; Amantadine sulfate; Pk-merz® 200mg/500ml inj(amantadine) , normal saline 500ml inj; | D00777 D07441 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
[17] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Rap1 signaling pathway, Ras signaling pathway, Systemic lupus erythematosus, cAMP signaling pathway |
[4] 6, 8, 13, 127 |
2 | Amiodarone | [3] Amiodarone; Diuretics (plus antiarrhythmic drugs, i.e. amiodarone, in case of complex ventricular arrhithmias); Diuretics (plus antiarrhythmic drugs, i.e. amiodarone, in case of complex ventricular arrhythmias) plus egcg; | D00636 D02910 |
[15] ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNJ11, KCNJ12, KCNJ3, KCNJ5, KCNJ8, KCNQ1, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A |
[30] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy (DCM), Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Insulin secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway |
[2] 28, 127 |
3 | Carbonate ion | - | - |
- |
- |
[10] 2, 13, 17, 19, 46, 75, 96, 127, 235, 299 |
4 | Chloride ion | - | - |
- |
- |
[17] 6, 11, 13, 14, 34, 46, 51, 96, 97, 127, 168, 193, 227, 228, 288, 297, 299 |
5 | Citalopram | [2] 20mg daily citalopram; Citalopram; | D00822 D07704 |
[1] SLC6A4 |
[2] Serotonergic synapse, Synaptic vesicle cycle |
[3] 8, 46, 127 |
6 | Davunetide | [2] Davunetide; Davunetide (al-108, nap); | D09401 |
- |
- |
[3] 5, 7, 127 |
7 | Donepezil | [4] Donepezil; Donepezil hci (drug); Donepezil hydrochloride; Donepezil sandoz; | D00670 D07869 |
[1] ACHE |
[2] Cholinergic synapse, Glycerophospholipid metabolism |
[9] 5, 6, 13, 46, 78, 124, 127, 156, 206 |
8 | Ferulic acid | [1] Ferulic acid; | - |
- |
- |
[1] 127 |
9 | Flortaucipir F-18 | - | - |
- |
- |
[3] 5, 7, 127 |
10 | Fludeoxyglucose F-18 | [1] Fludeoxyglucose f 18; | - |
- |
- |
[8] 6, 13, 34, 46, 53, 84, 127, 300 |
11 | Flutemetamol | [2] Flutemetamol; Vizamyl (flutemetamol(f-18)); | - |
- |
- |
[5] 5, 6, 7, 17, 127 |
12 | Galantamine | [2] Galantamine; Galantamine hydrobromide; | D02173 D04292 |
[1] ACHE |
[2] Cholinergic synapse, Glycerophospholipid metabolism |
[2] 6, 127 |
13 | L-Leucine | [1] L-leucine; | D00030 |
- |
- |
[7] 5, 6, 7, 127, 283, 284, 299 |
14 | Lithium carbonate | [1] Lithium carbonate; | D00801 |
- |
- |
[8] 2, 5, 7, 8, 13, 17, 19, 127 |
15 | Memantine | [3] Memantine; Memantine (ebixa); Memantine hydrochloride; | D04905 D08174 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
[17] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Rap1 signaling pathway, Ras signaling pathway, Systemic lupus erythematosus, cAMP signaling pathway |
[7] 2, 6, 8, 13, 49, 127, 205 |
16 | Methylene blue | [2] Methylene blue; Methylene blue 25mg tablets; | D02312 D10537 |
- |
- |
[2] 97, 127 |
17 | Methylthioninium | [3] Leuco-methylthioninium bis(hydromethanesulfonate); Methylthioninium; Methylthioninium chloride; | - |
- |
- |
[1] 127 |
18 | Oxytocin | [6] Intranasal oxytocin; Intranasal oxytocin (in-oxt); Oxytocin; Oxytocin (oxt) continuous; Oxytocin 24iu; Oxytocin 48iu; | D00089 |
[1] OXTR |
[4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway |
[4] 127, 193, 206, 226 |
19 | Phenothiazine | [3] N,n,n',n'-tetramethyl-10h-phenothiazine-3,7-diaminium bis(methanesulfonate); N,n,n’,n’-tetramethyl-10h-phenothiazine-3,7-diaminium bis(methanesulfonate); Phenothiazine; | D02601 |
- |
- |
[1] 127 |
20 | Pittsburgh Compound B | [2] Pittsburgh compound b; Pittsburgh compound b (c-11 pib); | - |
- |
- |
[2] 6, 127 |
21 | Tolcapone | [1] Tolcapone; | D00786 |
[1] COMT |
[4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism |
[3] 6, 28, 127 |