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   e.g. "Sirolimus", "Adalimumab"

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41 / 1,666 drugs found* Show info (disease name, etc.) on mouse-over.
 No.   DrugBank   Drug (Description in trials) 
 [Number of descriptions] 
 KEGG DRUG  KEGG GENES
 [Number of genes] 
 KEGG PATHWAY 
 [Number of pathways] 
 Disease ID
 [Number of diseases] 
 1   AZD-4017  [2] Azd4017; Azd4017 and prednisolone;   -   -   -   [1]
75
 2   Abiraterone  [2] Abiraterone; Abiraterone acetate;   D09701   -   -   [2]
75,
81
 3   Acetate  [76] 11c acetate; 11c-acetate; 20mg/0.5ml glatiramer acetate; 40 mg glatiramer acetate; [n-trans-3-hexenoyl] human growth hormone releasing factor (1-44) acetate; Abiraterone acetate; Acetate; Bazedoxifene acetate; Betamethasone sodium phosphate/betamethasone acetate (celestone® soluspan®), 30 mg im once a day for four days; Caspofungin acetate; Conventional glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone); Cortisone acetate; Cosyntropin acetate; Cyclophosphamide/glatiramer acetate; Delmitide acetate; Depot leuprolide acetate 3.75 mg; Desmopressin acetate; Desmopressin acetate trihydrate; Dirucotide acetate; Experimental glatiramer acetate; Flecainide acetate; Glatiramer acetate; Glatiramer acetate (copaxone®); Glatiramer acetate (db); Glatiramer acetate (ga); Glatiramer acetate (ga) 40 mg; Glatiramer acetate (ol); Glatiramer acetate 150mg enteric coated tablets; Glatiramer acetate 150mg enteric-coated (gastro-resistant) tablets; Glatiramer acetate 20 mg; Glatiramer acetate 20 mg, with mitoxantrone; Glatiramer acetate 20 mg/0.5 ml; Glatiramer acetate 40 mg; Glatiramer acetate injection with oral cetirizine hydrochloride; Glatiramer acetate with minocycline; Glatiramer acetate, (copaxone®); Glatiramer acetate, ifn-beta 1a (im), ifn-beta 1a (subcutaneous), and ifn-beta 1b; Glatiramer acetate, n-acetylcysteine; Gonadorelin acetate and triptorelin acetate; Human interferon beta-1a and glatiramer acetate; Hydrocortisone sodium acetate; L-lysyl-d-prolyl-l-threonine acetate; Lanreotide acetate; Leuprolide acetate (la); Leuprolide acetate 11.25 mg; Leuprolide acetate 3 month depot; Leuprolide acetate 30 mg; Leuprolide acetate 45 mg; Leuprolide acetate depot; Leuprorelin acetate; Leuprorelin acetate 3.75mg injection; Loestrin (norethindrone acetate and ethinyl estradiol); Loestrin 1.5/30 (1.5 mg norethindrone acetate/30 µg ethinyl estradiol); Luphere depot 3.75mg(leuprolide acetate 3.75mg); Lupron (leuprolide acetate); Macimorelin acetate; Megestrol acetate; Megestrol acetate tablet; Nomegestrol acetate; Phosphate and betamethasone acetate, 2 ml.; Plovamer acetate; Prednisolone acetate; Prednisone acetate; Prednisone acetate tablets; Sodium acetate; Sodium-[o-[(2,6-dichlorophenyl)-amino]-phenyl]-acetate; Sotrastaurin (inn) acetate; Tetracosactide acetate; Tocopherol acetate; Tocopheryl acetate; Triptorelin acetate and gonadorelin acetate; Ulipristal acetate; Zinc acetate; Zinc acetate (20mg/d); Zinc acetate dihydrate; Zuretinol acetate;   -   -   -   [40]
1,
2,
6,
10,
13,
35,
40,
46,
49,
51,
60,
64,
70,
71,
73,
75,
76,
78,
81,
83,
85,
86,
88,
90,
96,
97,
113,
145,
156,
162,
171,
206,
222,
224,
225,
235,
265,
288,
298,
299
 4   Aspartic acid  -  D00013   -   -   [3]
13,
75,
299
 5   Bexarotene  [1] Bexarotene;   D03106   [3] RXRA, RXRB, RXRG   [15] Adipocytokine signaling pathway, Bile secretion, Gastric cancer, Hepatitis C, Non-alcoholic fatty liver disease (NAFLD), Non-small cell lung cancer, PI3K-Akt signaling pathway, PPAR signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer   [2]
13,
75
 6   Cabergoline  [2] Cabergoline; Pasireotide with or without cabergoline;   D00987   [2] DRD2, PRL   [12] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway   [3]
6,
74,
75
 7   Calcium  [25] Amorphous calcium carbonate; Ascal(r) / carbasalate calcium; Atorvastatin calcium; Calcitriol & calcium; Calcium; Calcium and cholecalciferol; Calcium carbonate; Calcium carbonate and alphacalcidol; Calcium channel blockers; Calcium channel blockers (amlodipine, azelnidipine); Calcium citrate; Calcium citrate with vitamin d2; Calcium gluconate; Calcium lactate; Calcium levofolinate; Calcium rosuvastatin; Calcium, dietary; Carbasalate calcium; Crestor tablets (calcium rosuvastatin) film-coated tablets; Crystalline calcium supplements; Ibandronate+alfacalcidol+calcium; Low molecular weight heparin calcium injection; Rosuvastatin calcium; Symptomatic treatment (converting enzyme inhibitor, angiotensin ii, anti-renin, aldosterone antagonist diuretic, beta blocker, calcium inhibitor, statin); Vidofludimus calcium;   -   -   -   [24]
6,
13,
19,
46,
49,
51,
65,
68,
75,
79,
84,
93,
94,
95,
96,
97,
214,
215,
222,
224,
235,
265,
298,
299
 8   Calcium Carbonate  [3] Amorphous calcium carbonate; Calcium carbonate; Calcium carbonate and alphacalcidol;   D00932
 D10802 
 -   -   [7]
13,
19,
46,
75,
96,
235,
299
 9   Carbonate ion  -  -   -   -   [10]
2,
13,
17,
19,
46,
75,
96,
127,
235,
299
 10   Corticorelin  -  D03905   [2] CRHR1, CRHR2   [3] Cushing syndrome, Long-term depression, Neuroactive ligand-receptor interaction   [2]
75,
78
 11   Corticorelin ovine triflutate  -  D03592   [2] CRHR1, CRHR2   [3] Cushing syndrome, Long-term depression, Neuroactive ligand-receptor interaction   [1]
75
 12   Corticotropin  [8] Corticotropin; Corticotropin releasing hormone; Corticotropin-releasing hormone; H.p. acthar gel (repository corticotropin injection); H.p. acthar® gel (repository corticotropin injection); Ovine corticotropin-releasing hormone (ocrh); Repository corticotropin injection; Repository corticotropin injection -treatment extension;   D00146   [1] MC2R   [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway   [12]
2,
13,
46,
49,
50,
66,
75,
78,
84,
145,
193,
222
 13   Desmopressin  [7] Ddavp (desmopressin); Desmopressin; Desmopressin acetat; Desmopressin acetate; Desmopressin acetate trihydrate; Desmopressin intranasal; Desmopressin oral melt;   D00291
 D02235 
 [2] AVPR2, F8   [4] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption   [6]
6,
64,
72,
75,
225,
288
 14   Dexamethasone  [35] Bortezomib/dexamethasone (bd), followed by autologous stc & maintenance bortezomib/dexamethasone; Bupivacaine/epinephrine/dexamethasone; Combination of protein a immunoadsorption, rituximab, dexamethasone plus azathioprine; Control intervention (no dexamethasone); Conventional glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone); Cyclophosphamide, bortezomib, dexamethasone; Cyclophosphamide, bortezomib, dexamethasone plus daratumumab; Dexamethasone; Dexamethasone (1 cycle); Dexamethasone (4 cycles); Dexamethasone (50mg 1dd6, 3 consecutive days/month); Dexamethasone 0,5mg; Dexamethasone 0.5mg tablet; Dexamethasone 21-phosphate; Dexamethasone 2mg tablets; Dexamethasone abcur; Dexamethasone and rituximab; Dexamethasone parotid irrigation; Dexamethasone sodium phosphate; Dexamethasone sodium phosphate 250 mg/ 10 ml; Dexamethasone sodium phosphate 250 mg/10 ml solution; Dexamethasone sodium phosphate ph. eur.; Dexamethasone soduim phosphate; Dexamethasone, 40 mg; High dose dexamethasone pulses; Intraarticular dexamethasone; Intravenous dexamethasone 1 mg; Lenalidomide and dexamethasone; Lenalidomide+dexamethasone; Lenalidomide, dexamethasone; Lenalidomide, dexamethasone and cyclophosphamide; Melphalan, thalidomide and dexamethasone; Mmf and dexamethasone; Peri-neural dexamethasone 1 mg; Pomalidomide and dexamethasone;   D00292
 D00975
 D01510
 D01615
 D01632
 D01948
 D02174
 D02591
 D02592 
 [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [20]
13,
16,
28,
35,
46,
53,
63,
65,
70,
74,
75,
81,
83,
84,
90,
96,
97,
222,
296,
299
 15   Dotatate  [6] 68ga-dotatate; 68ga-dotatate pet/ct; Cu-64 dotatate; Dotatate; Dotatate pet-ct; Gallium-68 dotatate;   -   -   -   [3]
41,
75,
84
 16   Eplerenone  [1] Eplerenone;   D01115   [1] NR3C2   [1] Aldosterone-regulated sodium reabsorption   [3]
75,
113,
215
 17   Gefitinib  [1] Gefitinib;   D01977   [1] EGFR   [45] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis   [1]
75
 18   Hydrocortisone  [22] Combination oral budesonide and rectal hydrocortisone; Conventional glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone); Cortef (hydrocortisone); Dual release hydrocortisone (plenadren); Hydrocortisone; Hydrocortisone (solucortef); Hydrocortisone 10mg tablet; Hydrocortisone 20mg tablets; Hydrocortisone cream; Hydrocortisone cream 1%; Hydrocortisone cream 10mg/g fna fagron; Hydrocortisone efcortesol & solu-cortef; Hydrocortisone modified release capsules; Hydrocortisone roussel; Hydrocortisone sodium acetate; Hydrocortisone sodium phosphate; Hydrocortisone sodium succinate; Hydrocortisone takeda, tabletter; Mesalazine with hydrocortisone sodium succinate; Solu-cortef (hydrocortisone); Subcutaneous hydrocortisone; Subcutaneous hydrocortisone 10mg;   D00088   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [8]
6,
53,
75,
78,
81,
83,
97,
299
 19   Hydrocortisone acetate  -  D00165   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [8]
6,
53,
75,
78,
81,
83,
97,
299
 20   Ketoconazole  [2] Dimebon + ketoconazole; Ketoconazole;   D00351   [1] CYP17A1   [6] Cortisol synthesis and secretion, Cushing syndrome, Metabolic pathways, Ovarian steroidogenesis, Prolactin signaling pathway, Steroid hormone biosynthesis   [3]
8,
13,
75
 21   Lapatinib  [1] Lapatinib;   D04024
 D08108 
 [2] EGFR, ERBB2   [47] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Platinum drug resistance, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Tight junction   [3]
34,
74,
75
 22   Levoketoconazole  [1] Levoketoconazole;   D10950   -   -   [1]
75
 23   Liraglutide  [1] Liraglutide;   D06404   [1] GLP1R   [3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway   [3]
6,
75,
193
 24   Metformin  [12] 750 mg metformin and 7.5 g l-citrulline daily p.o.; Glucophage (metformin); L-citrulline and metformin & l-citrulline; Metformin; Metformin (generic); Metformin 500mg; Metformin and metformin & l-citrulline; Metformin hcl; Metformin hydrochloride; Metformin/cp-690,550; Pioglitazone or metformin; Sitagliptin and metformin;   D00944
 D04966 
 [2] PRKAA1, PRKAA2   [19] AMPK signaling pathway, Adipocytokine signaling pathway, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy (HCM), Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease (NAFLD), Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway   [17]
6,
13,
46,
49,
67,
75,
77,
81,
86,
113,
158,
206,
225,
233,
265,
285,
299
 25   Methionine  [7] [11c]-methionine; C11-methionine; L-methionine; L-methionine ([11c]methyl); Methionine; S-adenosyl-l-methionine; S-adenosyl-methionine (same) capsules;   D00019
 D04983 
 -   -   [6]
34,
75,
84,
93,
229,
300
 26   Metyrapone  [1] Metyrapone;   D00410
 D05019 
 [1] CYP11B1   [4] Cortisol synthesis and secretion, Cushing syndrome, Metabolic pathways, Steroid hormone biosynthesis   [2]
75,
193
 27   Mifepristone  [2] Hra052015 (mifepristone); Mifepristone;   D00585   [2] NR3C1, PGR   [5] Breast cancer, Estrogen signaling pathway, Neuroactive ligand-receptor interaction, Oocyte meiosis, Progesterone-mediated oocyte maturation   [1]
75
 28   Octreotide  [5] Gallium-68-dota-n-octreotide; Octreotide; Octreotide lar; Octreotide lar / sandostatin lar (lar=long acting release); Octreotide-lar;   D00442
 D06495 
 [1] SSTR2   [4] Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway   [8]
67,
75,
84,
85,
89,
96,
193,
227
 29   Osilodrostat  [5] Osilodrostat; Osilodrostat 10mg; Osilodrostat 1mg; Osilodrostat 20mg; Osilodrostat 5mg;   D11061   [1] CYP11B2   [3] Aldosterone synthesis and secretion, Metabolic pathways, Steroid hormone biosynthesis   [1]
75
 30   Pasireotide  [7] Pasireotide; Pasireotide 0.6 mg/ml; Pasireotide diaspartate; Pasireotide lar; Pasireotide pamoate; Pasireotide s.c.; Pasireotide with or without cabergoline;   D10147   [4] SSTR1, SSTR2, SSTR3, SSTR5   [4] Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway   [3]
67,
74,
75
 31   Pentetreotide  [1] Pentetreotide;   D01859   -   -   [1]
75
 32   Prednisolone  [46] Azd4017 and prednisolone; Conventional glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone); Corticosteroid (prednisolone); Corticosteroid treatment (methylprednisolone or prednisolone); Corticosteroids (prednisone or prednisolone); Etanercept, methotrexate, prednisolone; Glucocorticoid (prednisone or prednisolone); Intravenous methyl prednisolone; Long-circulating liposomal prednisolone; Low dose prednisolone; Medium dose prednisolone; Methotrexate - etanercept - prednisolone arm; Methyl prednisolone; Methylprednisolone or prednisolone; Oral prednisolone; Overencapsulated prednisolone tablets; Paroxetine & prednisolone; Paroxetine hydrochloride 10 & 20 mg and prednisolone 1 mg bp; Peg-liposomal prednisolone sodium phosphate; Prednisolone; Prednisolone & dipyridamole; Prednisolone + mabthera; Prednisolone 1mg tablets; Prednisolone 20 mg; Prednisolone 40 mg; Prednisolone 5 mg; Prednisolone 5mg tablet; Prednisolone acetate; Prednisolone and chlorambucil; Prednisolone and mycophenolate mofetil; Prednisolone and taper; Prednisolone sodium metasulphobenzoate; Prednisolone sodium phosphate; Prednisolone sodium succinate; Prednisolone tablets b.p. 5mg; Prednisolone tablets bp; Prednisolone tablets usp 5 mg; Prednisolone-dipyridamole; Prednisone or prednisolone; Prednisone/prednisolone; Pyridoxine plus prednisolone; Soluble prednisolone tablets; Sulphasalazine + hydroxychloroquine or prednisolone; Trexan+salazopyrin+oxiklorin+prednisolone; Trexan+salazopyrin+oxiklorin+prednisolone + infliximab; Z102 (prednisolone and dipyridamole).;   D00472
 D00980
 D00981
 D00982
 D01239
 D01998
 D02156
 D03301 
 [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [38]
11,
13,
25,
26,
35,
38,
39,
41,
43,
44,
45,
46,
49,
50,
51,
56,
60,
61,
63,
64,
65,
66,
75,
81,
84,
85,
95,
96,
97,
113,
145,
162,
222,
269,
271,
296,
299,
300
 33   Pyrazole  -  -   -   -   [2]
46,
75
 34   Relacorilant  [1] Relacorilant;   D11336   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [1]
75
 35   Rosiglitazone  [6] Recombinant human growth hormone + rosiglitazone; Rosiglitazone; Rosiglitazone (avandia); Rosiglitazone extended release tablets; Rosiglitazone maleate; Rosiglitazone xr;   D00596
 D08491 
 [1] PPARG   [9] AMPK signaling pathway, Huntington disease, Longevity regulating pathway, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer   [5]
46,
75,
97,
222,
265
 36   Seliciclib  [1] Seliciclib;   -   -   -   [2]
75,
299
 37   Sitagliptin  [2] Sitagliptin; Sitagliptin and metformin;   D08516   [1] DPP4   [1] Protein digestion and absorption   [3]
75,
233,
299
 38   Somatotropin  [2] Recombinant human somatotropin; Somatotropin;   D02691   [1] GHR   [5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway   [18]
2,
3,
13,
19,
46,
74,
75,
78,
96,
113,
191,
193,
195,
236,
265,
274,
276,
299
 39   Tadalafil  [11] Era and pde-5i (sildenafil, tadalafil, bosentan, macitentan); Fdc macitentan/tadalafil; Tadalafil; Tadalafil 20 mg; Tadalafil 20 mg film-coated tablets; Tadalafil 40 mg; Tadalafil and ambrisentan upfront combination therapy; Tadalafil and sildenafil; Tadalafil oral suspension; Tadalafil, placebo; Tadalafil- tablet or oral suspension;   D02008   [1] PDE5A   [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway   [6]
6,
51,
75,
84,
86,
113
 40   Tretinoin  [3] Pioglitazone and tretinoin; Tretinoin; Tretinoin and pioglitazone hcl;   D00094   [3] PML, RARA, RARB   [12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis   [5]
2,
63,
75,
94,
231
 41   Valsartan  [4] Benazepril, valsartan and fluvastatin; Enalapril valsartan methylprednisone; Sacubitril/valsartan; Valsartan;   D00400   [1] AGTR1   [14] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway   [6]
57,
58,
66,
75,
218,
222

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