| No. |
DrugBank |
Drug (Description in trials)
[Number of descriptions] |
KEGG DRUG * | KEGG GENES *
[Number of genes] |
KEGG PATHWAY
[Number of pathways] |
Disease ID *
[Number of diseases] |
| 1 | Acetate | [76] 11c acetate; 11c-acetate; 20mg/0.5ml glatiramer acetate; 40 mg glatiramer acetate; [n-trans-3-hexenoyl] human growth hormone releasing factor (1-44) acetate; Abiraterone acetate; Acetate; Bazedoxifene acetate; Betamethasone sodium phosphate/betamethasone acetate (celestone® soluspan®), 30 mg im once a day for four days; Caspofungin acetate; Conventional glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone); Cortisone acetate; Cosyntropin acetate; Cyclophosphamide/glatiramer acetate; Delmitide acetate; Depot leuprolide acetate 3.75 mg; Desmopressin acetate; Desmopressin acetate trihydrate; Dirucotide acetate; Experimental glatiramer acetate; Flecainide acetate; Glatiramer acetate; Glatiramer acetate (copaxone®); Glatiramer acetate (db); Glatiramer acetate (ga); Glatiramer acetate (ga) 40 mg; Glatiramer acetate (ol); Glatiramer acetate 150mg enteric coated tablets; Glatiramer acetate 150mg enteric-coated (gastro-resistant) tablets; Glatiramer acetate 20 mg; Glatiramer acetate 20 mg, with mitoxantrone; Glatiramer acetate 20 mg/0.5 ml; Glatiramer acetate 40 mg; Glatiramer acetate injection with oral cetirizine hydrochloride; Glatiramer acetate with minocycline; Glatiramer acetate, (copaxone®); Glatiramer acetate, ifn-beta 1a (im), ifn-beta 1a (subcutaneous), and ifn-beta 1b; Glatiramer acetate, n-acetylcysteine; Gonadorelin acetate and triptorelin acetate; Human interferon beta-1a and glatiramer acetate; Hydrocortisone sodium acetate; L-lysyl-d-prolyl-l-threonine acetate; Lanreotide acetate; Leuprolide acetate (la); Leuprolide acetate 11.25 mg; Leuprolide acetate 3 month depot; Leuprolide acetate 30 mg; Leuprolide acetate 45 mg; Leuprolide acetate depot; Leuprorelin acetate; Leuprorelin acetate 3.75mg injection; Loestrin (norethindrone acetate and ethinyl estradiol); Loestrin 1.5/30 (1.5 mg norethindrone acetate/30 µg ethinyl estradiol); Luphere depot 3.75mg(leuprolide acetate 3.75mg); Lupron (leuprolide acetate); Macimorelin acetate; Megestrol acetate; Megestrol acetate tablet; Nomegestrol acetate; Phosphate and betamethasone acetate, 2 ml.; Plovamer acetate; Prednisolone acetate; Prednisone acetate; Prednisone acetate tablets; Sodium acetate; Sodium-[o-[(2,6-dichlorophenyl)-amino]-phenyl]-acetate; Sotrastaurin (inn) acetate; Tetracosactide acetate; Tocopherol acetate; Tocopheryl acetate; Triptorelin acetate and gonadorelin acetate; Ulipristal acetate; Zinc acetate; Zinc acetate (20mg/d); Zinc acetate dihydrate; Zuretinol acetate; | - |
- |
- |
[40] 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 70, 71, 73, 75, 76, 78, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 235, 265, 288, 298, 299 |
| 2 | Acetic acid C-11 | - | - |
- |
- |
[3] 13, 86, 88 |
| 3 | Ambrisentan | [8] Ambrisentan; Ambrisentan - high dose; Ambrisentan - low dose; Ambrisentan 5 mg; Ambrisentan 5 mg film-coated tablets; Ambrisentan plus spironolactone; Bosentan, ambrisentan; Tadalafil and ambrisentan upfront combination therapy; | D07077 |
[1] EDNRA |
[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway |
[6] 51, 84, 85, 86, 88, 211 |
| 4 | Ammonia | [1] Ammonia; | D02916 |
- |
- |
[1] 88 |
| 5 | Atorvastatin | [9] Atorvastatin; Atorvastatin 10mg; Atorvastatin 20mg; Atorvastatin calcium; Atorvastatin tablet 20 mg; Interferon beta treatment to add-on atorvastatin treatment; Interferon beta-1b/atorvastatin group; Lisinopril, losartan, and atorvastatin; Untreated to atorvastatin treatment; | D00258
D00887
D07474 |
[1] HMGCR |
[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis |
[17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
| 6 | Bosentan | [14] Bosentan; Bosentan (tracleer); Bosentan 125 mg; Bosentan 62.5 mg; Bosentan administration; Bosentan and sildenafil; Bosentan group; Bosentan monohydrat; Bosentan monohydrate; Bosentan mylan; Bosentan, ambrisentan; Era and pde-5i (sildenafil, tadalafil, bosentan, macitentan); Sildenafil 20mg and bosentan 62.5mg; Sildenafil singly or in association with bosentan; | D01227
D07538 |
[2] EDNRA, EDNRB |
[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway |
[10] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
| 7 | D-glucose | [3] 2-deoxy-2 [f-18] fluoro-2-d-glucose; [18f]fluoro-2-deoxy-2-d-glucose; D-glucose; | D00009 |
- |
- |
[6] 6, 13, 49, 86, 88, 299 |
| 8 | Date | [1] Date; | - |
- |
- |
[3] 6, 88, 113 |
| 9 | Edoxaban | [1] Edoxaban; | D09546
D09710 |
[1] F10 |
[1] Complement and coagulation cascades |
[2] 46, 88 |
| 10 | Ethanol | [7] Andrographis paniculata (ethanol extract); Ethanol; Ethanol (96 per cent); Ethanol 96% gel; Ethanol 98% solution; Ethanol bp; Ethanol gel; | D00068
D02798
D04855
D06542 |
- |
- |
[49] 2, 11, 13, 14, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 58, 61, 63, 64, 65, 66, 81, 84, 85, 86, 88, 95, 96, 97, 113, 145, 162, 164, 222, 224, 228, 251, 279, 280, 283, 284, 285, 288, 298, 299, 300, 331 |
| 11 | Gadobenic acid | - | D04283
D08018 |
- |
- |
[3] 13, 86, 88 |
| 12 | Iodine | [1] Iodine; | D00108 |
- |
- |
[3] 28, 46, 88 |
| 13 | L-Cysteine | - | D00026
D02326 |
- |
- |
[9] 6, 13, 19, 84, 85, 88, 90, 254, 296 |
| 14 | Macitentan | [8] Act-064992 (macitentan); Era and pde-5i (sildenafil, tadalafil, bosentan, macitentan); Fdc macitentan/tadalafil; Macitentan; Macitentan 10 mg; Macitentan 10 mg tablet, once daily.; Macitentan group; Opsumit (macitentan); | D10135 |
[2] EDNRA, EDNRB |
[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway |
[5] 51, 85, 86, 88, 210 |
| 15 | Oxygen | [9] Continuous oxygen; Helium / oxygen mixed gas inhalation therapy; Medical air vs oxygen; Medical grade oxygen; Nitric oxide plus oxygen; Oxygen; Oxygen 40 %; Oxygen supplementation; Perfluorinated gas/oxygen mixture; | D00003 |
- |
- |
[18] 5, 6, 17, 46, 49, 70, 84, 85, 86, 88, 90, 96, 97, 193, 211, 226, 299, 330 |
| 16 | Potassium Iodide | - | D01016 |
- |
- |
[2] 46, 88 |
| 17 | Povidone-iodine | - | D00863 |
- |
- |
[2] 46, 88 |
| 18 | Riociguat | [12] Adempas (riociguat, bay63-2521); Riociguat; Riociguat (adempas, bay63-2521); Riociguat (bay63-2521); Riociguat coated tablet 0.5 mg; Riociguat coated tablet 1.0 mg; Riociguat coated tablet 1.5 mg; Riociguat coated tablet 2.0 mg; Riociguat coated tablet 2.5 mg; Riociguat granules 0.3% for oral application; Riociguat oral product; Riociguat pill; | D09572 |
[3] GUCY1A1, GUCY1A2, GUCY1B1 |
[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway |
[6] 51, 84, 86, 88, 225, 299 |
| 19 | Selexipag | [4] I.v. selexipag; Oral selexipag (uptravi); Selexipag; Selexipag (uptravi); | D09994 |
[1] PTGIR |
[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction |
[5] 51, 70, 84, 86, 88 |
| 20 | Sodium iodide | [2] Oncolytic measles virus encoding thyroidal sodium iodide symporter; Sodium iodide; | D04874
D05328
D05863 |
- |
- |
[3] 34, 46, 88 |
| 21 | Thrombin | [1] Thrombin; | D00090 |
- |
- |
[2] 86, 88 |
| 22 | Treprostinil | [31] Eutonic treprostinil solution; Inhaled dry powder treprostinil (liq861); Inhaled treprostinil; Intravenous treprostinil; Intravenous/subcutaneous treprostinil; Iontophoresis of treprostinil; Liq861 inhaled treprostinil; Oral treprostinil; Oral treprostinil (ut-15c) sustained release tablets; Parenteral remodulin (treprostinil) injection; Rapid dose titration group of subcutaneous treprostinil; Remodulin (treprostinil sodium); Remodulin® (treprostinil) 1 mg/ml solution for infusion; Remodulin® (treprostinil) 10 mg/ml solution for infusion; Remodulin® (treprostinil) 2.5 mg/ml solution for infusion; Remodulin® (treprostinil) 5 mg/ml solution for infusion; Slow dose titration group of subcutaneous treprostinil; Subcutaneous treprostinil; Treprostinil; Treprostinil diethanolamine; Treprostinil diolamine; Treprostinil inhalation powder; Treprostinil inhalations; Treprostinil injectable product; Treprostinil sodium; Treprostinil sodium for inhalation; Treprostinil sodium solution for inhalation; Treprostinil sodium, ut-15; Treprostinil, ut-15, lrx-15, 15au81, bw a15au, u-62, 840; Ut-15c (treprostinil diethanolamine); Ut-15c sr (treprostinil diethanolamine); | D06213 |
[1] PTGIR |
[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction |
[5] 51, 84, 85, 86, 88 |
| 23 | Warfarin | [4] S-warfarin; The generic name is warfarin and many producers will be involved; Warfarin; Warfarin 10 mg; | D00564
D01280
D08682 |
[2] NQO1, VKORC1 |
[5] Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis |
[10] 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 |