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 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

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14 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY * 
 On map, Yellow: Drug target, Red: Disease-related 		  KEGG GENES * 
 [Number of genes] 		  KEGG DRUG *   DrugBank   Disease ID * 
 [Number of diseases] 
 1  Adrenergic signaling in cardiomyocytes 
 1 gene, 1 drug (DrugBank), 5 diseases shown 		  [1] SCN5A   D00639   Mexiletine   [5] 1, 2, 10, 113, 114 
 D08215 
 2  Breast cancer 
 1 gene, 1 drug (DrugBank), 1 disease shown 		  [1] PGR   D09567   Ulipristal   [1] 10 
 3  cAMP signaling pathway 
 2 genes, 1 drug (DrugBank), 5 diseases shown 		  [2] GABBR1, GABBR2   D00241   Baclofen   [5] 2, 10, 13, 18, 149 
 4  cGMP-PKG signaling pathway 
 1 gene, 1 drug (DrugBank), 11 diseases shown 		  [1] OPRD1   D02095   Naltrexone   [11] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 
 D05113 
 5  Dopaminergic synapse 
 1 gene, 1 drug (DrugBank), 5 diseases shown 		  [1] SCN1A   D00639   Mexiletine   [5] 1, 2, 10, 113, 114 
 D08215 
 6  Estrogen signaling pathway 
 4 genes, 3 drugs (DrugBank), 14 diseases shown 		  [2] GABBR1, GABBR2   D00241   Baclofen   [5] 2, 10, 13, 18, 149 
 [1] OPRM1   D02095   Naltrexone   [11] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 
 D05113 
 [1] PGR   D09567   Ulipristal   [1] 10 
 7  GABAergic synapse 
 2 genes, 1 drug (DrugBank), 5 diseases shown 		  [2] GABBR1, GABBR2   D00241   Baclofen   [5] 2, 10, 13, 18, 149 
 8  GnRH secretion 
 2 genes, 1 drug (DrugBank), 5 diseases shown 		  [2] GABBR1, GABBR2   D00241   Baclofen   [5] 2, 10, 13, 18, 149 
 9  Morphine addiction 
 3 genes, 2 drugs (DrugBank), 14 diseases shown 		  [2] GABBR1, GABBR2   D00241   Baclofen   [5] 2, 10, 13, 18, 149 
 [1] OPRM1   D02095   Naltrexone   [11] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 
 D05113 
 10  Neuroactive ligand-receptor interaction 
 6 genes, 3 drugs (DrugBank), 21 diseases shown 		  [2] GABBR1, GABBR2   D00241   Baclofen   [5] 2, 10, 13, 18, 149 
 [1] NR3C1   D00385   Triamcinolone   [18] 6, 10, 13, 35, 40, 41, 42, 43, 44, 45, 46, 56, 70, 90, 96, 97, 226, 298 
 D00983 
 D00984 
 D00985 
 D06216 
 [3] OPRD1, OPRK1, OPRM1   D02095   Naltrexone   [11] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 
 D05113 
 11  Oocyte meiosis 
 1 gene, 1 drug (DrugBank), 1 disease shown 		  [1] PGR   D09567   Ulipristal   [1] 10 
 12  Progesterone-mediated oocyte maturation 
 1 gene, 1 drug (DrugBank), 1 disease shown 		  [1] PGR   D09567   Ulipristal   [1] 10 
 13  Sphingolipid signaling pathway 
 1 gene, 1 drug (DrugBank), 11 diseases shown 		  [1] OPRD1   D02095   Naltrexone   [11] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 
 D05113 
 14  Taste transduction 
 5 genes, 2 drugs (DrugBank), 8 diseases shown 		  [2] GABBR1, GABBR2   D00241   Baclofen   [5] 2, 10, 13, 18, 149 
 [3] SCN2A, SCN3A, SCN9A   D00639   Mexiletine   [5] 1, 2, 10, 113, 114 
 D08215 

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