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 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

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40 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY * 
 On map, Yellow: Drug target, Red: Disease-related 		  KEGG GENES * 
 [Number of genes] 		  KEGG DRUG *   DrugBank   Disease ID * 
 [Number of diseases] 
 1  African trypanosomiasis 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 2  AGE-RAGE signaling pathway in diabetic complications 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 3  Alzheimer disease 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 4  Amoebiasis 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 5  Antifolate resistance 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 6  C-type lectin receptor signaling pathway 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 7  Chagas disease (American trypanosomiasis) 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 8  Cytokine-cytokine receptor interaction 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 9  Cytosolic DNA-sensing pathway 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 10  Fluid shear stress and atherosclerosis 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 11  Graft-versus-host disease 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 12  Hematopoietic cell lineage 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 13  Herpes simplex virus 1 infection 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 14  Human cytomegalovirus infection 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 15  IL-17 signaling pathway 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 16  Inflammatory bowel disease (IBD) 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 17  Inflammatory mediator regulation of TRP channels 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 18  Influenza A 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 19  Legionellosis 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 20  Leishmaniasis 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 21  Malaria 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 22  MAPK signaling pathway 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 23  Measles 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 24  Necroptosis 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 25  NF-kappa B signaling pathway 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 26  NOD-like receptor signaling pathway 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 27  Non-alcoholic fatty liver disease (NAFLD) 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 28  Osteoclast differentiation 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 29  Pathogenic Escherichia coli infection 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 30  Pertussis 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 31  Prion diseases 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 32  Rheumatoid arthritis 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 33  Salmonella infection 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 34  Shigellosis 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 35  Th17 cell differentiation 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 36  TNF signaling pathway 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 37  Toll-like receptor signaling pathway 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 38  Tuberculosis 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 39  Type I diabetes mellitus 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 
 40  Yersinia infection 
 1 gene, 1 drug (DrugBank), 9 diseases shown 		  [1] IL1B   D09315   Canakinumab   [9] 46, 56, 84, 106, 107, 108, 113, 266, 269 

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