DDrare: Database of Drug Development for Rare Diseases

Target Gene/Pathway

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10 / 275 pathways found* Show info (disease name, etc.) on mouse-over.

No.	KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related	KEGG GENES * [Number of genes]	KEGG DRUG *	DrugBank	Disease ID * [Number of diseases]
1	Adrenergic signaling in cardiomyocytes 1 gene, 2 drugs (DrugBank), 7 diseases shown	[1] SCN5A	D00354	Lamotrigine	[3] 13, 34, 114
			D00639	Mexiletine	[5] 1, 2, 10, 113, 114
			D08215	Mexiletine	[5] 1, 2, 10, 113, 114
2	Bile secretion 1 gene, 1 drug (DrugBank), 1 disease shown	[1] CA2	D00518	Diclofenamide	[1] 114
3	Collecting duct acid secretion 1 gene, 1 drug (DrugBank), 1 disease shown	[1] CA2	D00518	Diclofenamide	[1] 114
4	Dopaminergic synapse 1 gene, 2 drugs (DrugBank), 7 diseases shown	[1] SCN1A	D00354	Lamotrigine	[3] 13, 34, 114
			D00639	Mexiletine	[5] 1, 2, 10, 113, 114
			D08215	Mexiletine	[5] 1, 2, 10, 113, 114
5	Gastric acid secretion 1 gene, 1 drug (DrugBank), 1 disease shown	[1] CA2	D00518	Diclofenamide	[1] 114
6	Metabolic pathways 13 genes, 1 drug (DrugBank), 1 disease shown	[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9	D00518	Diclofenamide	[1] 114
7	Nitrogen metabolism 13 genes, 1 drug (DrugBank), 1 disease shown	[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9	D00518	Diclofenamide	[1] 114
8	Pancreatic secretion 1 gene, 1 drug (DrugBank), 1 disease shown	[1] CA2	D00518	Diclofenamide	[1] 114
9	Proximal tubule bicarbonate reclamation 2 genes, 1 drug (DrugBank), 1 disease shown	[2] CA2, CA4	D00518	Diclofenamide	[1] 114
10	Taste transduction 3 genes, 2 drugs (DrugBank), 7 diseases shown	[3] SCN2A, SCN3A, SCN9A	D00354	Lamotrigine	[3] 13, 34, 114
			D00639	Mexiletine	[5] 1, 2, 10, 113, 114
			D08215	Mexiletine	[5] 1, 2, 10, 113, 114