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 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

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19 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY * 
 On map, Yellow: Drug target, Red: Disease-related 		  KEGG GENES * 
 [Number of genes] 		  KEGG DRUG *   DrugBank   Disease ID * 
 [Number of diseases] 
 1  Alanine, aspartate and glutamate metabolism 
 1 gene, 1 drug (DrugBank), 2 diseases shown 		  [1] ABAT   D00535   Vigabatrin   [2] 145, 158 
 2  Aldosterone synthesis and secretion 
 1 gene, 2 drugs (DrugBank), 14 diseases shown 		  [1] MC2R   D00146   Corticotropin   [12] 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 
 D00284   Tetracosactide   [5] 78, 83, 113, 145, 222 
 3  beta-Alanine metabolism 
 1 gene, 1 drug (DrugBank), 2 diseases shown 		  [1] ABAT   D00535   Vigabatrin   [2] 145, 158 
 4  Butanoate metabolism 
 1 gene, 1 drug (DrugBank), 2 diseases shown 		  [1] ABAT   D00535   Vigabatrin   [2] 145, 158 
 5  cAMP signaling pathway 
 1 gene, 2 drugs (DrugBank), 14 diseases shown 		  [1] MC2R   D00146   Corticotropin   [12] 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 
 D00284   Tetracosactide   [5] 78, 83, 113, 145, 222 
 6  Cortisol synthesis and secretion 
 1 gene, 2 drugs (DrugBank), 14 diseases shown 		  [1] MC2R   D00146   Corticotropin   [12] 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 
 D00284   Tetracosactide   [5] 78, 83, 113, 145, 222 
 7  Cushing syndrome 
 1 gene, 2 drugs (DrugBank), 14 diseases shown 		  [1] MC2R   D00146   Corticotropin   [12] 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 
 D00284   Tetracosactide   [5] 78, 83, 113, 145, 222 
 8  GABAergic synapse 
 17 genes, 2 drugs (DrugBank), 4 diseases shown 		  [1] ABAT   D00535   Vigabatrin   [2] 145, 158 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D04300   Ganaxolone   [3] 145, 152, 206 
 9  Metabolic pathways 
 1 gene, 1 drug (DrugBank), 2 diseases shown 		  [1] ABAT   D00535   Vigabatrin   [2] 145, 158 
 10  Morphine addiction 
 16 genes, 1 drug (DrugBank), 3 diseases shown 		  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D04300   Ganaxolone   [3] 145, 152, 206 
 11  Neuroactive ligand-receptor interaction 
 20 genes, 7 drugs (DrugBank), 64 diseases shown 		  [2] CNR1, CNR2   D10915   Cannabidiol   [14] 2, 6, 13, 46, 95, 96, 97, 140, 144, 145, 157, 158, 193, 271 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D04300   Ganaxolone   [3] 145, 152, 206 
 [1] MC2R   D00146   Corticotropin   [12] 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 
 D00284   Tetracosactide   [5] 78, 83, 113, 145, 222 
 [1] NR3C1   D00407   Methylprednisolone   [36] 2, 13, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 145, 164, 220, 222, 224, 271, 283, 284, 285, 296 
 D00751 
 D00979 
 D05000 
 D05001 
 D05002 
 D00472   Prednisolone   [38] 11, 13, 25, 26, 35, 38, 39, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 
 D00980 
 D00981 
 D00982 
 D01239 
 D01998 
 D02156 
 D03301 
 D00473   Prednisone   [44] 2, 11, 13, 14, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 95, 96, 97, 113, 145, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 
 12  Nicotine addiction 
 16 genes, 1 drug (DrugBank), 3 diseases shown 		  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D04300   Ganaxolone   [3] 145, 152, 206 
 13  Propanoate metabolism 
 1 gene, 1 drug (DrugBank), 2 diseases shown 		  [1] ABAT   D00535   Vigabatrin   [2] 145, 158 
 14  Rap1 signaling pathway 
 1 gene, 1 drug (DrugBank), 14 diseases shown 		  [1] CNR1   D10915   Cannabidiol   [14] 2, 6, 13, 46, 95, 96, 97, 140, 144, 145, 157, 158, 193, 271 
 15  Retrograde endocannabinoid signaling 
 17 genes, 2 drugs (DrugBank), 16 diseases shown 		  [1] CNR1   D10915   Cannabidiol   [14] 2, 6, 13, 46, 95, 96, 97, 140, 144, 145, 157, 158, 193, 271 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D04300   Ganaxolone   [3] 145, 152, 206 
 16  Serotonergic synapse 
 3 genes, 1 drug (DrugBank), 3 diseases shown 		  [3] GABRB1, GABRB2, GABRB3   D04300   Ganaxolone   [3] 145, 152, 206 
 17  Taste transduction 
 6 genes, 1 drug (DrugBank), 3 diseases shown 		  [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6   D04300   Ganaxolone   [3] 145, 152, 206 
 18  Thermogenesis 
 1 gene, 1 drug (DrugBank), 14 diseases shown 		  [1] CNR1   D10915   Cannabidiol   [14] 2, 6, 13, 46, 95, 96, 97, 140, 144, 145, 157, 158, 193, 271 
 19  Valine, leucine and isoleucine degradation 
 1 gene, 1 drug (DrugBank), 2 diseases shown 		  [1] ABAT   D00535   Vigabatrin   [2] 145, 158 

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