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 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

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11 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY * 
 On map, Yellow: Drug target, Red: Disease-related 		  KEGG GENES * 
 [Number of genes] 		  KEGG DRUG *   DrugBank   Disease ID * 
 [Number of diseases] 
 1  cAMP signaling pathway 
 2 genes, 1 drug (DrugBank), 5 diseases shown 		  [2] GABBR1, GABBR2   D00241   Baclofen   [5] 2, 10, 13, 18, 149 
 2  Cholinergic synapse 
 2 genes, 1 drug (DrugBank), 2 diseases shown 		  [2] CHRNA4, CHRNB2   D08669   Varenicline   [2] 6, 18 
 3  Estrogen signaling pathway 
 2 genes, 1 drug (DrugBank), 5 diseases shown 		  [2] GABBR1, GABBR2   D00241   Baclofen   [5] 2, 10, 13, 18, 149 
 4  GABAergic synapse 
 18 genes, 2 drugs (DrugBank), 8 diseases shown 		  [2] GABBR1, GABBR2   D00241   Baclofen   [5] 2, 10, 13, 18, 149 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00697   Flumazenil   [5] 6, 13, 17, 18, 206 
 5  GnRH secretion 
 2 genes, 1 drug (DrugBank), 5 diseases shown 		  [2] GABBR1, GABBR2   D00241   Baclofen   [5] 2, 10, 13, 18, 149 
 6  Morphine addiction 
 18 genes, 2 drugs (DrugBank), 8 diseases shown 		  [2] GABBR1, GABBR2   D00241   Baclofen   [5] 2, 10, 13, 18, 149 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00697   Flumazenil   [5] 6, 13, 17, 18, 206 
 7  Neuroactive ligand-receptor interaction 
 20 genes, 3 drugs (DrugBank), 8 diseases shown 		  [2] CHRNA4, CHRNB2   D08669   Varenicline   [2] 6, 18 
 [2] GABBR1, GABBR2   D00241   Baclofen   [5] 2, 10, 13, 18, 149 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00697   Flumazenil   [5] 6, 13, 17, 18, 206 
 8  Nicotine addiction 
 18 genes, 2 drugs (DrugBank), 5 diseases shown 		  [2] CHRNA4, CHRNB2   D08669   Varenicline   [2] 6, 18 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00697   Flumazenil   [5] 6, 13, 17, 18, 206 
 9  Retrograde endocannabinoid signaling 
 16 genes, 1 drug (DrugBank), 5 diseases shown 		  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00697   Flumazenil   [5] 6, 13, 17, 18, 206 
 10  Serotonergic synapse 
 3 genes, 1 drug (DrugBank), 5 diseases shown 		  [3] GABRB1, GABRB2, GABRB3   D00697   Flumazenil   [5] 6, 13, 17, 18, 206 
 11  Taste transduction 
 8 genes, 2 drugs (DrugBank), 8 diseases shown 		  [2] GABBR1, GABBR2   D00241   Baclofen   [5] 2, 10, 13, 18, 149 
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6   D00697   Flumazenil   [5] 6, 13, 17, 18, 206 

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