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 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

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9 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY * 
 On map, Yellow: Drug target, Red: Disease-related 		  KEGG GENES * 
 [Number of genes] 		  KEGG DRUG *   DrugBank   Disease ID * 
 [Number of diseases] 
 1  AMPK signaling pathway 
 1 gene, 2 drugs (DrugBank), 23 diseases shown 		  [1] HMGCR   D00359   Lovastatin   [10] 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 
 D00434   Simvastatin   [19] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 
 2  Bile secretion 
 1 gene, 2 drugs (DrugBank), 23 diseases shown 		  [1] HMGCR   D00359   Lovastatin   [10] 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 
 D00434   Simvastatin   [19] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 
 3  Cytokine-cytokine receptor interaction 
 1 gene, 1 drug (DrugBank), 18 diseases shown 		  [1] GHR   D02691   Somatotropin   [18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 
 4  Growth hormone synthesis, secretion and action 
 1 gene, 1 drug (DrugBank), 18 diseases shown 		  [1] GHR   D02691   Somatotropin   [18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 
 5  JAK-STAT signaling pathway 
 1 gene, 1 drug (DrugBank), 18 diseases shown 		  [1] GHR   D02691   Somatotropin   [18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 
 6  Metabolic pathways 
 1 gene, 2 drugs (DrugBank), 23 diseases shown 		  [1] HMGCR   D00359   Lovastatin   [10] 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 
 D00434   Simvastatin   [19] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 
 7  Neuroactive ligand-receptor interaction 
 1 gene, 1 drug (DrugBank), 18 diseases shown 		  [1] GHR   D02691   Somatotropin   [18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 
 8  PI3K-Akt signaling pathway 
 1 gene, 1 drug (DrugBank), 18 diseases shown 		  [1] GHR   D02691   Somatotropin   [18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 
 9  Terpenoid backbone biosynthesis 
 1 gene, 2 drugs (DrugBank), 23 diseases shown 		  [1] HMGCR   D00359   Lovastatin   [10] 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 
 D00434   Simvastatin   [19] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 

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