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 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

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20 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY * 
 On map, Yellow: Drug target, Red: Disease-related 		  KEGG GENES * 
 [Number of genes] 		  KEGG DRUG *   DrugBank   Disease ID * 
 [Number of diseases] 
 1  Alcoholism 
 3 genes, 2 drugs (DrugBank), 8 diseases shown 		  [1] DDC   D00558   Carbidopa   [8] 2, 4, 6, 13, 17, 90, 164, 201 
 [2] DRD1, DRD2   D00059   Levodopa   [7] 2, 4, 6, 17, 90, 164, 201 
 2  Amphetamine addiction 
 2 genes, 2 drugs (DrugBank), 8 diseases shown 		  [1] DDC   D00558   Carbidopa   [8] 2, 4, 6, 13, 17, 90, 164, 201 
 [1] DRD1   D00059   Levodopa   [7] 2, 4, 6, 17, 90, 164, 201 
 3  Calcium signaling pathway 
 2 genes, 1 drug (DrugBank), 7 diseases shown 		  [2] DRD1, DRD5   D00059   Levodopa   [7] 2, 4, 6, 17, 90, 164, 201 
 4  cAMP signaling pathway 
 3 genes, 1 drug (DrugBank), 7 diseases shown 		  [3] DRD1, DRD2, DRD5   D00059   Levodopa   [7] 2, 4, 6, 17, 90, 164, 201 
 5  Cocaine addiction 
 3 genes, 2 drugs (DrugBank), 8 diseases shown 		  [1] DDC   D00558   Carbidopa   [8] 2, 4, 6, 13, 17, 90, 164, 201 
 [2] DRD1, DRD2   D00059   Levodopa   [7] 2, 4, 6, 17, 90, 164, 201 
 6  Dopaminergic synapse 
 6 genes, 2 drugs (DrugBank), 8 diseases shown 		  [1] DDC   D00558   Carbidopa   [8] 2, 4, 6, 13, 17, 90, 164, 201 
 [5] DRD1, DRD2, DRD3, DRD4, DRD5   D00059   Levodopa   [7] 2, 4, 6, 17, 90, 164, 201 
 7  GABAergic synapse 
 16 genes, 1 drug (DrugBank), 2 diseases shown 		  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D04282   Gaboxadol   [2] 201, 206 
 8  Gap junction 
 2 genes, 1 drug (DrugBank), 7 diseases shown 		  [2] DRD1, DRD2   D00059   Levodopa   [7] 2, 4, 6, 17, 90, 164, 201 
 9  Metabolic pathways 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] DDC   D00558   Carbidopa   [8] 2, 4, 6, 13, 17, 90, 164, 201 
 10  Morphine addiction 
 17 genes, 2 drugs (DrugBank), 8 diseases shown 		  [1] DRD1   D00059   Levodopa   [7] 2, 4, 6, 17, 90, 164, 201 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D04282   Gaboxadol   [2] 201, 206 
 11  Neuroactive ligand-receptor interaction 
 21 genes, 2 drugs (DrugBank), 8 diseases shown 		  [5] DRD1, DRD2, DRD3, DRD4, DRD5   D00059   Levodopa   [7] 2, 4, 6, 17, 90, 164, 201 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D04282   Gaboxadol   [2] 201, 206 
 12  Nicotine addiction 
 16 genes, 1 drug (DrugBank), 2 diseases shown 		  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D04282   Gaboxadol   [2] 201, 206 
 13  Parkinson disease 
 2 genes, 1 drug (DrugBank), 7 diseases shown 		  [2] DRD1, DRD2   D00059   Levodopa   [7] 2, 4, 6, 17, 90, 164, 201 
 14  Phenylalanine metabolism 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] DDC   D00558   Carbidopa   [8] 2, 4, 6, 13, 17, 90, 164, 201 
 15  Rap1 signaling pathway 
 1 gene, 1 drug (DrugBank), 7 diseases shown 		  [1] DRD2   D00059   Levodopa   [7] 2, 4, 6, 17, 90, 164, 201 
 16  Retrograde endocannabinoid signaling 
 16 genes, 1 drug (DrugBank), 2 diseases shown 		  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D04282   Gaboxadol   [2] 201, 206 
 17  Serotonergic synapse 
 4 genes, 2 drugs (DrugBank), 9 diseases shown 		  [1] DDC   D00558   Carbidopa   [8] 2, 4, 6, 13, 17, 90, 164, 201 
 [3] GABRB1, GABRB2, GABRB3   D04282   Gaboxadol   [2] 201, 206 
 18  Taste transduction 
 6 genes, 1 drug (DrugBank), 2 diseases shown 		  [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6   D04282   Gaboxadol   [2] 201, 206 
 19  Tryptophan metabolism 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] DDC   D00558   Carbidopa   [8] 2, 4, 6, 13, 17, 90, 164, 201 
 20  Tyrosine metabolism 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] DDC   D00558   Carbidopa   [8] 2, 4, 6, 13, 17, 90, 164, 201 

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