No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * [Number of genes] |
KEGG DRUG * |
DrugBank |
Disease ID * [Number of diseases] |
1 | Alcoholism 5 genes, 1 drug (DrugBank), 7 diseases shown |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
2 | Alzheimer disease 5 genes, 1 drug (DrugBank), 7 diseases shown |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
3 | Amphetamine addiction 5 genes, 1 drug (DrugBank), 7 diseases shown |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
4 | Amyotrophic lateral sclerosis (ALS) 5 genes, 1 drug (DrugBank), 7 diseases shown |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
5 | Calcium signaling pathway 4 genes, 1 drug (DrugBank), 7 diseases shown |
[4] GRIN1, GRIN2A, GRIN2C, GRIN2D |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
6 | cAMP signaling pathway 5 genes, 1 drug (DrugBank), 7 diseases shown |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
7 | Circadian entrainment 5 genes, 1 drug (DrugBank), 7 diseases shown |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
8 | Cocaine addiction 5 genes, 1 drug (DrugBank), 7 diseases shown |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
9 | Dopaminergic synapse 2 genes, 1 drug (DrugBank), 7 diseases shown |
[2] GRIN2A, GRIN2B |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
10 | GABAergic synapse 16 genes, 1 drug (DrugBank), 1 disease shown |
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D11149 |
Brexanolone |
[1] 205 |
11 | Glutamatergic synapse 5 genes, 1 drug (DrugBank), 7 diseases shown |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
12 | Huntington disease 2 genes, 1 drug (DrugBank), 7 diseases shown |
[2] GRIN1, GRIN2B |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
13 | Long-term potentiation 5 genes, 1 drug (DrugBank), 7 diseases shown |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
14 | Morphine addiction 16 genes, 1 drug (DrugBank), 1 disease shown |
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D11149 |
Brexanolone |
[1] 205 |
15 | Neuroactive ligand-receptor interaction 21 genes, 2 drugs (DrugBank), 7 diseases shown |
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D11149 |
Brexanolone |
[1] 205 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
16 | Nicotine addiction 21 genes, 2 drugs (DrugBank), 7 diseases shown |
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D11149 |
Brexanolone |
[1] 205 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
17 | Rap1 signaling pathway 3 genes, 1 drug (DrugBank), 7 diseases shown |
[3] GRIN1, GRIN2A, GRIN2B |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
18 | Ras signaling pathway 3 genes, 1 drug (DrugBank), 7 diseases shown |
[3] GRIN1, GRIN2A, GRIN2B |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
19 | Retrograde endocannabinoid signaling 16 genes, 1 drug (DrugBank), 1 disease shown |
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D11149 |
Brexanolone |
[1] 205 |
20 | Serotonergic synapse 3 genes, 1 drug (DrugBank), 1 disease shown |
[3] GABRB1, GABRB2, GABRB3 |
D11149 |
Brexanolone |
[1] 205 |
21 | Systemic lupus erythematosus 2 genes, 1 drug (DrugBank), 7 diseases shown |
[2] GRIN2A, GRIN2B |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
22 | Taste transduction 6 genes, 1 drug (DrugBank), 1 disease shown |
[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 |
D11149 |
Brexanolone |
[1] 205 |