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 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

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5 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY
 On map, Yellow: Drug target, Red: Disease-related 
 KEGG GENES
 [Number of genes] 
 KEGG DRUG  DrugBank   Disease ID
 [Number of diseases] 
 1  cGMP-PKG signaling pathway 
 4 genes, 2 drugs (DrugBank), 23 diseases shown 
 [3] ADRA2A, ADRA2B, ADRA2C   D00514   Dexmedetomidine   [11] 2, 4, 6, 21, 34, 70, 113, 212, 215, 226, 280 
 D01205 
 [1] PDE5A   D02229   Sildenafil   [16] 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 
 D08514 
 2  Metabolic pathways 
 1 gene, 1 drug (DrugBank), 16 diseases shown 
 [1] PDE5A   D02229   Sildenafil   [16] 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 
 D08514 
 3  Neuroactive ligand-receptor interaction 
 5 genes, 2 drugs (DrugBank), 13 diseases shown 
 [3] ADRA2A, ADRA2B, ADRA2C   D00514   Dexmedetomidine   [11] 2, 4, 6, 21, 34, 70, 113, 212, 215, 226, 280 
 D01205 
 [2] THRA, THRB   D01011   Liothyronine   [3] 13, 78, 212 
 D08128 
 4  Purine metabolism 
 1 gene, 1 drug (DrugBank), 16 diseases shown 
 [1] PDE5A   D02229   Sildenafil   [16] 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 
 D08514 
 5  Thyroid hormone signaling pathway 
 2 genes, 1 drug (DrugBank), 3 diseases shown 
 [2] THRA, THRB   D01011   Liothyronine   [3] 13, 78, 212 
 D08128 

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