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 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

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25 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY * 
 On map, Yellow: Drug target, Red: Disease-related 		  KEGG GENES * 
 [Number of genes] 		  KEGG DRUG *   DrugBank   Disease ID * 
 [Number of diseases] 
 1  Adrenergic signaling in cardiomyocytes 
 1 gene, 1 drug (DrugBank), 6 diseases shown 		  [1] AGTR1   D00400   Valsartan   [6] 57, 58, 66, 75, 218, 222 
 2  AGE-RAGE signaling pathway in diabetic complications 
 1 gene, 1 drug (DrugBank), 6 diseases shown 		  [1] AGTR1   D00400   Valsartan   [6] 57, 58, 66, 75, 218, 222 
 3  Aldosterone synthesis and secretion 
 1 gene, 1 drug (DrugBank), 6 diseases shown 		  [1] AGTR1   D00400   Valsartan   [6] 57, 58, 66, 75, 218, 222 
 4  Aldosterone-regulated sodium reabsorption 
 1 gene, 1 drug (DrugBank), 6 diseases shown 		  [1] NR3C2   D00443   Spironolactone   [6] 58, 67, 86, 113, 218, 225 
 5  AMPK signaling pathway 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] HMGCR   D00892   Fluvastatin   [3] 79, 218, 222 
 D07983 
 6  Apelin signaling pathway 
 1 gene, 1 drug (DrugBank), 6 diseases shown 		  [1] AGTR1   D00400   Valsartan   [6] 57, 58, 66, 75, 218, 222 
 7  Bile secretion 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] HMGCR   D00892   Fluvastatin   [3] 79, 218, 222 
 D07983 
 8  Calcium signaling pathway 
 1 gene, 1 drug (DrugBank), 6 diseases shown 		  [1] AGTR1   D00400   Valsartan   [6] 57, 58, 66, 75, 218, 222 
 9  cGMP-PKG signaling pathway 
 1 gene, 1 drug (DrugBank), 6 diseases shown 		  [1] AGTR1   D00400   Valsartan   [6] 57, 58, 66, 75, 218, 222 
 10  Chagas disease (American trypanosomiasis) 
 1 gene, 2 drugs (DrugBank), 9 diseases shown 		  [1] ACE   D00620   Benazepril   [3] 57, 218, 224 
 D07499 
 D00421   Ramipril   [7] 46, 49, 66, 67, 113, 218, 257 
 11  Cortisol synthesis and secretion 
 1 gene, 1 drug (DrugBank), 6 diseases shown 		  [1] AGTR1   D00400   Valsartan   [6] 57, 58, 66, 75, 218, 222 
 12  Cushing syndrome 
 1 gene, 1 drug (DrugBank), 6 diseases shown 		  [1] AGTR1   D00400   Valsartan   [6] 57, 58, 66, 75, 218, 222 
 13  Endocrine and other factor-regulated calcium reabsorption 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] VDR   D00930   Paricalcitol   [3] 19, 66, 218 
 14  Hypertrophic cardiomyopathy (HCM) 
 1 gene, 2 drugs (DrugBank), 9 diseases shown 		  [1] ACE   D00620   Benazepril   [3] 57, 218, 224 
 D07499 
 D00421   Ramipril   [7] 46, 49, 66, 67, 113, 218, 257 
 15  Metabolic pathways 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] HMGCR   D00892   Fluvastatin   [3] 79, 218, 222 
 D07983 
 16  Mineral absorption 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] VDR   D00930   Paricalcitol   [3] 19, 66, 218 
 17  Neuroactive ligand-receptor interaction 
 1 gene, 1 drug (DrugBank), 6 diseases shown 		  [1] AGTR1   D00400   Valsartan   [6] 57, 58, 66, 75, 218, 222 
 18  Parathyroid hormone synthesis, secretion and action 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] VDR   D00930   Paricalcitol   [3] 19, 66, 218 
 19  Pathways in cancer 
 1 gene, 1 drug (DrugBank), 6 diseases shown 		  [1] AGTR1   D00400   Valsartan   [6] 57, 58, 66, 75, 218, 222 
 20  Phospholipase D signaling pathway 
 1 gene, 1 drug (DrugBank), 6 diseases shown 		  [1] AGTR1   D00400   Valsartan   [6] 57, 58, 66, 75, 218, 222 
 21  Renin secretion 
 2 genes, 3 drugs (DrugBank), 12 diseases shown 		  [1] ACE   D00620   Benazepril   [3] 57, 218, 224 
 D07499 
 D00421   Ramipril   [7] 46, 49, 66, 67, 113, 218, 257 
 [1] AGTR1   D00400   Valsartan   [6] 57, 58, 66, 75, 218, 222 
 22  Renin-angiotensin system 
 2 genes, 3 drugs (DrugBank), 12 diseases shown 		  [1] ACE   D00620   Benazepril   [3] 57, 218, 224 
 D07499 
 D00421   Ramipril   [7] 46, 49, 66, 67, 113, 218, 257 
 [1] AGTR1   D00400   Valsartan   [6] 57, 58, 66, 75, 218, 222 
 23  Terpenoid backbone biosynthesis 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] HMGCR   D00892   Fluvastatin   [3] 79, 218, 222 
 D07983 
 24  Tuberculosis 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] VDR   D00930   Paricalcitol   [3] 19, 66, 218 
 25  Vascular smooth muscle contraction 
 1 gene, 1 drug (DrugBank), 6 diseases shown 		  [1] AGTR1   D00400   Valsartan   [6] 57, 58, 66, 75, 218, 222 

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