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 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

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30 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY
 On map, Yellow: Drug target, Red: Disease-related 
 KEGG GENES
 [Number of genes] 
 KEGG DRUG  DrugBank   Disease ID
 [Number of diseases] 
 1  Arachidonic acid metabolism 
 2 genes, 1 drug (DrugBank), 10 diseases shown 
 [2] PTGS1, PTGS2   D00109   Acetylsalicylic acid   [10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 
 2  C-type lectin receptor signaling pathway 
 1 gene, 1 drug (DrugBank), 10 diseases shown 
 [1] PTGS2   D00109   Acetylsalicylic acid   [10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 
 3  Chemical carcinogenesis 
 1 gene, 1 drug (DrugBank), 10 diseases shown 
 [1] PTGS2   D00109   Acetylsalicylic acid   [10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 
 4  Cytokine-cytokine receptor interaction 
 1 gene, 1 drug (DrugBank), 9 diseases shown 
 [1] EPOR   D03231   Erythropoietin   [9] 2, 6, 13, 22, 46, 47, 70, 95, 96 
 5  GABAergic synapse 
 16 genes, 1 drug (DrugBank), 8 diseases shown 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00549   Propofol   [8] 6, 21, 22, 34, 46, 84, 98, 296 
 6  Hematopoietic cell lineage 
 1 gene, 1 drug (DrugBank), 9 diseases shown 
 [1] EPOR   D03231   Erythropoietin   [9] 2, 6, 13, 22, 46, 47, 70, 95, 96 
 7  Human cytomegalovirus infection 
 1 gene, 1 drug (DrugBank), 10 diseases shown 
 [1] PTGS2   D00109   Acetylsalicylic acid   [10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 
 8  Human papillomavirus infection 
 1 gene, 1 drug (DrugBank), 10 diseases shown 
 [1] PTGS2   D00109   Acetylsalicylic acid   [10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 
 9  IL-17 signaling pathway 
 1 gene, 1 drug (DrugBank), 10 diseases shown 
 [1] PTGS2   D00109   Acetylsalicylic acid   [10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 
 10  JAK-STAT signaling pathway 
 1 gene, 1 drug (DrugBank), 9 diseases shown 
 [1] EPOR   D03231   Erythropoietin   [9] 2, 6, 13, 22, 46, 47, 70, 95, 96 
 11  Kaposi sarcoma-associated herpesvirus infection 
 1 gene, 1 drug (DrugBank), 10 diseases shown 
 [1] PTGS2   D00109   Acetylsalicylic acid   [10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 
 12  Leishmaniasis 
 1 gene, 1 drug (DrugBank), 10 diseases shown 
 [1] PTGS2   D00109   Acetylsalicylic acid   [10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 
 13  Metabolic pathways 
 2 genes, 1 drug (DrugBank), 10 diseases shown 
 [2] PTGS1, PTGS2   D00109   Acetylsalicylic acid   [10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 
 14  MicroRNAs in cancer 
 1 gene, 1 drug (DrugBank), 10 diseases shown 
 [1] PTGS2   D00109   Acetylsalicylic acid   [10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 
 15  Morphine addiction 
 16 genes, 1 drug (DrugBank), 8 diseases shown 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00549   Propofol   [8] 6, 21, 22, 34, 46, 84, 98, 296 
 16  Neuroactive ligand-receptor interaction 
 16 genes, 1 drug (DrugBank), 8 diseases shown 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00549   Propofol   [8] 6, 21, 22, 34, 46, 84, 98, 296 
 17  NF-kappa B signaling pathway 
 1 gene, 1 drug (DrugBank), 10 diseases shown 
 [1] PTGS2   D00109   Acetylsalicylic acid   [10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 
 18  Nicotine addiction 
 16 genes, 1 drug (DrugBank), 8 diseases shown 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00549   Propofol   [8] 6, 21, 22, 34, 46, 84, 98, 296 
 19  Ovarian steroidogenesis 
 1 gene, 1 drug (DrugBank), 10 diseases shown 
 [1] PTGS2   D00109   Acetylsalicylic acid   [10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 
 20  Oxytocin signaling pathway 
 1 gene, 1 drug (DrugBank), 10 diseases shown 
 [1] PTGS2   D00109   Acetylsalicylic acid   [10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 
 21  Pathways in cancer 
 2 genes, 2 drugs (DrugBank), 16 diseases shown 
 [1] EPOR   D03231   Erythropoietin   [9] 2, 6, 13, 22, 46, 47, 70, 95, 96 
 [1] PTGS2   D00109   Acetylsalicylic acid   [10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 
 22  PI3K-Akt signaling pathway 
 1 gene, 1 drug (DrugBank), 9 diseases shown 
 [1] EPOR   D03231   Erythropoietin   [9] 2, 6, 13, 22, 46, 47, 70, 95, 96 
 23  Platelet activation 
 1 gene, 1 drug (DrugBank), 10 diseases shown 
 [1] PTGS1   D00109   Acetylsalicylic acid   [10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 
 24  Regulation of lipolysis in adipocytes 
 2 genes, 1 drug (DrugBank), 10 diseases shown 
 [2] PTGS1, PTGS2   D00109   Acetylsalicylic acid   [10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 
 25  Retrograde endocannabinoid signaling 
 17 genes, 2 drugs (DrugBank), 15 diseases shown 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00549   Propofol   [8] 6, 21, 22, 34, 46, 84, 98, 296 
 [1] PTGS2   D00109   Acetylsalicylic acid   [10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 
 26  Serotonergic synapse 
 5 genes, 2 drugs (DrugBank), 15 diseases shown 
 [3] GABRB1, GABRB2, GABRB3   D00549   Propofol   [8] 6, 21, 22, 34, 46, 84, 98, 296 
 [2] PTGS1, PTGS2   D00109   Acetylsalicylic acid   [10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 
 27  Small cell lung cancer 
 1 gene, 1 drug (DrugBank), 10 diseases shown 
 [1] PTGS2   D00109   Acetylsalicylic acid   [10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 
 28  Taste transduction 
 6 genes, 1 drug (DrugBank), 8 diseases shown 
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6   D00549   Propofol   [8] 6, 21, 22, 34, 46, 84, 98, 296 
 29  TNF signaling pathway 
 1 gene, 1 drug (DrugBank), 10 diseases shown 
 [1] PTGS2   D00109   Acetylsalicylic acid   [10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 
 30  VEGF signaling pathway 
 1 gene, 1 drug (DrugBank), 10 diseases shown 
 [1] PTGS2   D00109   Acetylsalicylic acid   [10] 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 

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