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 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

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12 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY * 
 On map, Yellow: Drug target, Red: Disease-related 		  KEGG GENES * 
 [Number of genes] 		  KEGG DRUG *   DrugBank   Disease ID * 
 [Number of diseases] 
 1  AMPK signaling pathway 
 1 gene, 1 drug (DrugBank), 17 diseases shown 		  [1] PPARG   D00945   Pioglitazone   [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 
 D08378 
 2  Cytokine-cytokine receptor interaction 
 1 gene, 3 drugs (DrugBank), 10 diseases shown 		  [1] CSF2RA   D05066   Molgramostim   [2] 229, 299 
 D05712   Regramostim   [4] 11, 46, 51, 229 
 D05803   Sargramostim   [6] 6, 28, 60, 62, 96, 229 
 3  Hematopoietic cell lineage 
 2 genes, 4 drugs (DrugBank), 46 diseases shown 		  [1] CSF2RA   D05066   Molgramostim   [2] 229, 299 
 D05712   Regramostim   [4] 11, 46, 51, 229 
 D05803   Sargramostim   [6] 6, 28, 60, 62, 96, 229 
 [1] MS4A1   D02994   Rituximab   [42] 11, 13, 14, 17, 35, 36, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 223, 229, 256, 271, 283, 284, 285, 288, 300, 331 
 4  Huntington disease 
 1 gene, 1 drug (DrugBank), 17 diseases shown 		  [1] PPARG   D00945   Pioglitazone   [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 
 D08378 
 5  JAK-STAT signaling pathway 
 1 gene, 3 drugs (DrugBank), 10 diseases shown 		  [1] CSF2RA   D05066   Molgramostim   [2] 229, 299 
 D05712   Regramostim   [4] 11, 46, 51, 229 
 D05803   Sargramostim   [6] 6, 28, 60, 62, 96, 229 
 6  Longevity regulating pathway 
 1 gene, 1 drug (DrugBank), 17 diseases shown 		  [1] PPARG   D00945   Pioglitazone   [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 
 D08378 
 7  Osteoclast differentiation 
 1 gene, 1 drug (DrugBank), 17 diseases shown 		  [1] PPARG   D00945   Pioglitazone   [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 
 D08378 
 8  Pathways in cancer 
 2 genes, 4 drugs (DrugBank), 22 diseases shown 		  [1] CSF2RA   D05066   Molgramostim   [2] 229, 299 
 D05712   Regramostim   [4] 11, 46, 51, 229 
 D05803   Sargramostim   [6] 6, 28, 60, 62, 96, 229 
 [1] PPARG   D00945   Pioglitazone   [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 
 D08378 
 9  PPAR signaling pathway 
 1 gene, 1 drug (DrugBank), 17 diseases shown 		  [1] PPARG   D00945   Pioglitazone   [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 
 D08378 
 10  Thermogenesis 
 1 gene, 1 drug (DrugBank), 17 diseases shown 		  [1] PPARG   D00945   Pioglitazone   [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 
 D08378 
 11  Thyroid cancer 
 1 gene, 1 drug (DrugBank), 17 diseases shown 		  [1] PPARG   D00945   Pioglitazone   [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 
 D08378 
 12  Transcriptional misregulation in cancer 
 1 gene, 1 drug (DrugBank), 17 diseases shown 		  [1] PPARG   D00945   Pioglitazone   [17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 
 D08378 

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