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 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

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75 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY
 On map, Yellow: Drug target, Red: Disease-related 
 KEGG GENES
 [Number of genes] 
 KEGG DRUG  DrugBank   Disease ID
 [Number of diseases] 
 1  Adrenergic signaling in cardiomyocytes 
 1 gene, 1 drug (DrugBank), 13 diseases shown 
 [1] ADRB2   D02147   Salbutamol   [13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 
 2  Alanine, aspartate and glutamate metabolism 
 4 genes, 1 drug (DrugBank), 14 diseases shown 
 [4] ABAT, ALDH5A1, GAD1, GAD2   D00399   Valproic Acid   [14] 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 3  Alcoholism 
 5 genes, 1 drug (DrugBank), 7 diseases shown 
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00775   Riluzole   [7] 2, 3, 5, 8, 13, 17, 206 
 4  Aldosterone synthesis and secretion 
 3 genes, 1 drug (DrugBank), 14 diseases shown 
 [3] CACNA1G, CACNA1H, CACNA1I   D00399   Valproic Acid   [14] 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 5  Alzheimer disease 
 5 genes, 1 drug (DrugBank), 7 diseases shown 
 [5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00775   Riluzole   [7] 2, 3, 5, 8, 13, 17, 206 
 6  Amphetamine addiction 
 9 genes, 1 drug (DrugBank), 7 diseases shown 
 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00775   Riluzole   [7] 2, 3, 5, 8, 13, 17, 206 
 7  Amyotrophic lateral sclerosis (ALS) 
 7 genes, 1 drug (DrugBank), 7 diseases shown 
 [7] GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00775   Riluzole   [7] 2, 3, 5, 8, 13, 17, 206 
 8  Arachidonic acid metabolism 
 2 genes, 2 drugs (DrugBank), 17 diseases shown 
 [2] PTGS1, PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 [1] PTGS2   D00567   Celecoxib   [9] 2, 3, 34, 46, 70, 89, 96, 161, 271 
 9  beta-Alanine metabolism 
 3 genes, 1 drug (DrugBank), 14 diseases shown 
 [3] ABAT, GAD1, GAD2   D00399   Valproic Acid   [14] 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 10  Butanoate metabolism 
 4 genes, 1 drug (DrugBank), 14 diseases shown 
 [4] ABAT, ALDH5A1, GAD1, GAD2   D00399   Valproic Acid   [14] 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 11  C-type lectin receptor signaling pathway 
 1 gene, 2 drugs (DrugBank), 17 diseases shown 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 D00567   Celecoxib   [9] 2, 3, 34, 46, 70, 89, 96, 161, 271 
 12  Calcium signaling pathway 
 9 genes, 4 drugs (DrugBank), 26 diseases shown 
 [1] ADRB2   D02147   Salbutamol   [13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 
 [3] CACNA1G, CACNA1H, CACNA1I   D00399   Valproic Acid   [14] 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 [4] GRIN1, GRIN2A, GRIN2C, GRIN2D   D00775   Riluzole   [7] 2, 3, 5, 8, 13, 17, 206 
 [1] TNNC2   D11363   Reldesemtiv   [2] 2, 3 
 13  cAMP signaling pathway 
 10 genes, 2 drugs (DrugBank), 18 diseases shown 
 [1] ADRB2   D02147   Salbutamol   [13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 
 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00775   Riluzole   [7] 2, 3, 5, 8, 13, 17, 206 
 14  cGMP-PKG signaling pathway 
 1 gene, 1 drug (DrugBank), 13 diseases shown 
 [1] ADRB2   D02147   Salbutamol   [13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 
 15  Chemical carcinogenesis 
 1 gene, 2 drugs (DrugBank), 17 diseases shown 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 D00567   Celecoxib   [9] 2, 3, 34, 46, 70, 89, 96, 161, 271 
 16  Cholinergic synapse 
 1 gene, 1 drug (DrugBank), 4 diseases shown 
 [1] ACHE   D00487   Pyridostigmine   [4] 3, 6, 11, 256 
 17  Circadian entrainment 
 12 genes, 2 drugs (DrugBank), 17 diseases shown 
 [3] CACNA1G, CACNA1H, CACNA1I   D00399   Valproic Acid   [14] 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00775   Riluzole   [7] 2, 3, 5, 8, 13, 17, 206 
 18  Cocaine addiction 
 6 genes, 1 drug (DrugBank), 7 diseases shown 
 [6] GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00775   Riluzole   [7] 2, 3, 5, 8, 13, 17, 206 
 19  Cortisol synthesis and secretion 
 4 genes, 3 drugs (DrugBank), 18 diseases shown 
 [3] CACNA1G, CACNA1H, CACNA1I   D00399   Valproic Acid   [14] 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 [1] KCNA4   D10228   Amifampridine   [3] 3, 11, 12 
 D04127   Dalfampridine   [3] 3, 4, 13 
 20  Cushing syndrome 
 4 genes, 3 drugs (DrugBank), 18 diseases shown 
 [3] CACNA1G, CACNA1H, CACNA1I   D00399   Valproic Acid   [14] 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 [1] KCNA4   D10228   Amifampridine   [3] 3, 11, 12 
 D04127   Dalfampridine   [3] 3, 4, 13 
 21  Cytokine-cytokine receptor interaction 
 1 gene, 1 drug (DrugBank), 18 diseases shown 
 [1] GHR   D02691   Somatotropin   [18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 
 22  Dopaminergic synapse 
 6 genes, 1 drug (DrugBank), 7 diseases shown 
 [6] GRIA1, GRIA2, GRIA3, GRIA4, GRIN2A, GRIN2B   D00775   Riluzole   [7] 2, 3, 5, 8, 13, 17, 206 
 23  Drug metabolism - other enzymes 
 1 gene, 1 drug (DrugBank), 8 diseases shown 
 [1] RRM2   D00341   Hydroxyurea   [8] 3, 13, 19, 20, 65, 85, 86, 284 
 24  GABAergic synapse 
 19 genes, 2 drugs (DrugBank), 22 diseases shown 
 [3] ABAT, GAD1, GAD2   D00399   Valproic Acid   [14] 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00550   Midazolam   [10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 
 D00696 
 D05028 
 25  Glutamatergic synapse 
 14 genes, 1 drug (DrugBank), 7 diseases shown 
 [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00775   Riluzole   [7] 2, 3, 5, 8, 13, 17, 206 
 26  Glutathione metabolism 
 1 gene, 1 drug (DrugBank), 8 diseases shown 
 [1] RRM2   D00341   Hydroxyurea   [8] 3, 13, 19, 20, 65, 85, 86, 284 
 27  Glycerophospholipid metabolism 
 1 gene, 1 drug (DrugBank), 4 diseases shown 
 [1] ACHE   D00487   Pyridostigmine   [4] 3, 6, 11, 256 
 28  GnRH secretion 
 3 genes, 1 drug (DrugBank), 14 diseases shown 
 [3] CACNA1G, CACNA1H, CACNA1I   D00399   Valproic Acid   [14] 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 29  GnRH signaling pathway 
 1 gene, 1 drug (DrugBank), 5 diseases shown 
 [1] GNRHR   D00989   Leuprolide   [5] 1, 2, 3, 51, 76 
 30  Growth hormone synthesis, secretion and action 
 1 gene, 1 drug (DrugBank), 18 diseases shown 
 [1] GHR   D02691   Somatotropin   [18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 
 31  Human cytomegalovirus infection 
 1 gene, 2 drugs (DrugBank), 17 diseases shown 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 D00567   Celecoxib   [9] 2, 3, 34, 46, 70, 89, 96, 161, 271 
 32  Human papillomavirus infection 
 1 gene, 2 drugs (DrugBank), 17 diseases shown 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 D00567   Celecoxib   [9] 2, 3, 34, 46, 70, 89, 96, 161, 271 
 33  Huntington disease 
 2 genes, 1 drug (DrugBank), 7 diseases shown 
 [2] GRIN1, GRIN2B   D00775   Riluzole   [7] 2, 3, 5, 8, 13, 17, 206 
 34  IL-17 signaling pathway 
 1 gene, 2 drugs (DrugBank), 17 diseases shown 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 D00567   Celecoxib   [9] 2, 3, 34, 46, 70, 89, 96, 161, 271 
 35  JAK-STAT signaling pathway 
 1 gene, 1 drug (DrugBank), 18 diseases shown 
 [1] GHR   D02691   Somatotropin   [18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 
 36  Kaposi sarcoma-associated herpesvirus infection 
 1 gene, 2 drugs (DrugBank), 17 diseases shown 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 D00567   Celecoxib   [9] 2, 3, 34, 46, 70, 89, 96, 161, 271 
 37  Leishmaniasis 
 1 gene, 2 drugs (DrugBank), 17 diseases shown 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 D00567   Celecoxib   [9] 2, 3, 34, 46, 70, 89, 96, 161, 271 
 38  Long-term depression 
 3 genes, 1 drug (DrugBank), 7 diseases shown 
 [3] GRIA1, GRIA2, GRIA3   D00775   Riluzole   [7] 2, 3, 5, 8, 13, 17, 206 
 39  Long-term potentiation 
 7 genes, 1 drug (DrugBank), 7 diseases shown 
 [7] GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00775   Riluzole   [7] 2, 3, 5, 8, 13, 17, 206 
 40  MAPK signaling pathway 
 3 genes, 1 drug (DrugBank), 14 diseases shown 
 [3] CACNA1G, CACNA1H, CACNA1I   D00399   Valproic Acid   [14] 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 41  Metabolic pathways 
 7 genes, 4 drugs (DrugBank), 30 diseases shown 
 [4] ABAT, ALDH5A1, GAD1, GAD2   D00399   Valproic Acid   [14] 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 [2] PTGS1, PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 [1] PTGS2   D00567   Celecoxib   [9] 2, 3, 34, 46, 70, 89, 96, 161, 271 
 [1] RRM2   D00341   Hydroxyurea   [8] 3, 13, 19, 20, 65, 85, 86, 284 
 42  MicroRNAs in cancer 
 1 gene, 2 drugs (DrugBank), 17 diseases shown 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 D00567   Celecoxib   [9] 2, 3, 34, 46, 70, 89, 96, 161, 271 
 43  Morphine addiction 
 16 genes, 1 drug (DrugBank), 10 diseases shown 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00550   Midazolam   [10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 
 D00696 
 D05028 
 44  Neuroactive ligand-receptor interaction 
 33 genes, 5 drugs (DrugBank), 38 diseases shown 
 [1] ADRB2   D02147   Salbutamol   [13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00550   Midazolam   [10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 
 D00696 
 D05028 
 [1] GHR   D02691   Somatotropin   [18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 
 [1] GNRHR   D00989   Leuprolide   [5] 1, 2, 3, 51, 76 
 [14] GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00775   Riluzole   [7] 2, 3, 5, 8, 13, 17, 206 
 45  NF-kappa B signaling pathway 
 1 gene, 2 drugs (DrugBank), 17 diseases shown 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 D00567   Celecoxib   [9] 2, 3, 34, 46, 70, 89, 96, 161, 271 
 46  Nicotine addiction 
 25 genes, 2 drugs (DrugBank), 14 diseases shown 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00550   Midazolam   [10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 
 D00696 
 D05028 
 [9] GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D   D00775   Riluzole   [7] 2, 3, 5, 8, 13, 17, 206 
 47  Oocyte meiosis 
 1 gene, 1 drug (DrugBank), 7 diseases shown 
 [1] AR   D00075   Testosterone   [7] 1, 2, 3, 13, 78, 113, 265 
 D00957 
 D00958 
 D00959 
 D06085 
 D06087 
 48  Ovarian steroidogenesis 
 1 gene, 2 drugs (DrugBank), 17 diseases shown 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 D00567   Celecoxib   [9] 2, 3, 34, 46, 70, 89, 96, 161, 271 
 49  Oxytocin signaling pathway 
 1 gene, 2 drugs (DrugBank), 17 diseases shown 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 D00567   Celecoxib   [9] 2, 3, 34, 46, 70, 89, 96, 161, 271 
 50  p53 signaling pathway 
 1 gene, 1 drug (DrugBank), 8 diseases shown 
 [1] RRM2   D00341   Hydroxyurea   [8] 3, 13, 19, 20, 65, 85, 86, 284 
 51  Pathways in cancer 
 2 genes, 3 drugs (DrugBank), 21 diseases shown 
 [1] AR   D00075   Testosterone   [7] 1, 2, 3, 13, 78, 113, 265 
 D00957 
 D00958 
 D00959 
 D06085 
 D06087 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 D00567   Celecoxib   [9] 2, 3, 34, 46, 70, 89, 96, 161, 271 
 52  PI3K-Akt signaling pathway 
 1 gene, 1 drug (DrugBank), 18 diseases shown 
 [1] GHR   D02691   Somatotropin   [18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 
 53  Platelet activation 
 1 gene, 1 drug (DrugBank), 13 diseases shown 
 [1] PTGS1   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 54  Propanoate metabolism 
 1 gene, 1 drug (DrugBank), 14 diseases shown 
 [1] ABAT   D00399   Valproic Acid   [14] 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 55  Prostate cancer 
 1 gene, 1 drug (DrugBank), 7 diseases shown 
 [1] AR   D00075   Testosterone   [7] 1, 2, 3, 13, 78, 113, 265 
 D00957 
 D00958 
 D00959 
 D06085 
 D06087 
 56  Purine metabolism 
 1 gene, 1 drug (DrugBank), 8 diseases shown 
 [1] RRM2   D00341   Hydroxyurea   [8] 3, 13, 19, 20, 65, 85, 86, 284 
 57  Pyrimidine metabolism 
 1 gene, 1 drug (DrugBank), 8 diseases shown 
 [1] RRM2   D00341   Hydroxyurea   [8] 3, 13, 19, 20, 65, 85, 86, 284 
 58  Rap1 signaling pathway 
 3 genes, 1 drug (DrugBank), 7 diseases shown 
 [3] GRIN1, GRIN2A, GRIN2B   D00775   Riluzole   [7] 2, 3, 5, 8, 13, 17, 206 
 59  Ras signaling pathway 
 3 genes, 1 drug (DrugBank), 7 diseases shown 
 [3] GRIN1, GRIN2A, GRIN2B   D00775   Riluzole   [7] 2, 3, 5, 8, 13, 17, 206 
 60  Regulation of lipolysis in adipocytes 
 3 genes, 3 drugs (DrugBank), 23 diseases shown 
 [1] ADRB2   D02147   Salbutamol   [13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 
 [2] PTGS1, PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 [1] PTGS2   D00567   Celecoxib   [9] 2, 3, 34, 46, 70, 89, 96, 161, 271 
 61  Renin secretion 
 1 gene, 1 drug (DrugBank), 13 diseases shown 
 [1] ADRB2   D02147   Salbutamol   [13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 
 62  Retrograde endocannabinoid signaling 
 21 genes, 4 drugs (DrugBank), 23 diseases shown 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00550   Midazolam   [10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 
 D00696 
 D05028 
 [4] GRIA1, GRIA2, GRIA3, GRIA4   D00775   Riluzole   [7] 2, 3, 5, 8, 13, 17, 206 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 D00567   Celecoxib   [9] 2, 3, 34, 46, 70, 89, 96, 161, 271 
 63  RNA transport 
 1 gene, 2 drugs (DrugBank), 1 disease shown 
 [1] SMN2   D10881   Nusinersen   [1] 3 
 D11406   Risdiplam   [1] 3 
 64  Salivary secretion 
 1 gene, 1 drug (DrugBank), 13 diseases shown 
 [1] ADRB2   D02147   Salbutamol   [13] 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 
 65  Serotonergic synapse 
 6 genes, 5 drugs (DrugBank), 22 diseases shown 
 [3] GABRB1, GABRB2, GABRB3   D00550   Midazolam   [10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 
 D00696 
 D05028 
 [1] KCND2   D10228   Amifampridine   [3] 3, 11, 12 
 D04127   Dalfampridine   [3] 3, 4, 13 
 [2] PTGS1, PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 [1] PTGS2   D00567   Celecoxib   [9] 2, 3, 34, 46, 70, 89, 96, 161, 271 
 66  Small cell lung cancer 
 1 gene, 2 drugs (DrugBank), 17 diseases shown 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 D00567   Celecoxib   [9] 2, 3, 34, 46, 70, 89, 96, 161, 271 
 67  Systemic lupus erythematosus 
 2 genes, 1 drug (DrugBank), 7 diseases shown 
 [2] GRIN2A, GRIN2B   D00775   Riluzole   [7] 2, 3, 5, 8, 13, 17, 206 
 68  Taste transduction 
 6 genes, 1 drug (DrugBank), 10 diseases shown 
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6   D00550   Midazolam   [10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 
 D00696 
 D05028 
 69  Taurine and hypotaurine metabolism 
 2 genes, 1 drug (DrugBank), 14 diseases shown 
 [2] GAD1, GAD2   D00399   Valproic Acid   [14] 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 70  TNF signaling pathway 
 1 gene, 2 drugs (DrugBank), 17 diseases shown 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 D00567   Celecoxib   [9] 2, 3, 34, 46, 70, 89, 96, 161, 271 
 71  Transcriptional misregulation in cancer 
 1 gene, 1 drug (DrugBank), 7 diseases shown 
 [1] GRIA3   D00775   Riluzole   [7] 2, 3, 5, 8, 13, 17, 206 
 72  Type I diabetes mellitus 
 2 genes, 1 drug (DrugBank), 14 diseases shown 
 [2] GAD1, GAD2   D00399   Valproic Acid   [14] 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 73  Type II diabetes mellitus 
 1 gene, 1 drug (DrugBank), 14 diseases shown 
 [1] CACNA1G   D00399   Valproic Acid   [14] 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 74  Valine, leucine and isoleucine degradation 
 1 gene, 1 drug (DrugBank), 14 diseases shown 
 [1] ABAT   D00399   Valproic Acid   [14] 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 
 75  VEGF signaling pathway 
 1 gene, 2 drugs (DrugBank), 17 diseases shown 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 D00567   Celecoxib   [9] 2, 3, 34, 46, 70, 89, 96, 161, 271 

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