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 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

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32 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY * 
 On map, Yellow: Drug target, Red: Disease-related 		  KEGG GENES * 
 [Number of genes] 		  KEGG DRUG *   DrugBank   Disease ID * 
 [Number of diseases] 
 1  Adipocytokine signaling pathway 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 2  AGE-RAGE signaling pathway in diabetic complications 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 3  Chemokine signaling pathway 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 4  Cholinergic synapse 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 5  EGFR tyrosine kinase inhibitor resistance 
 2 genes, 1 drug (DrugBank), 8 diseases shown 		  [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 6  Epstein-Barr virus infection 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK1   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 7  Growth hormone synthesis, secretion and action 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 8  Hepatitis B 
 2 genes, 1 drug (DrugBank), 8 diseases shown 		  [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 9  Hepatitis C 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK1   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 10  Herpes simplex virus 1 infection 
 2 genes, 1 drug (DrugBank), 8 diseases shown 		  [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 11  Human cytomegalovirus infection 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK1   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 12  Human papillomavirus infection 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK1   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 13  Human T-cell leukemia virus 1 infection 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK1   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 14  Influenza A 
 2 genes, 1 drug (DrugBank), 8 diseases shown 		  [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 15  JAK-STAT signaling pathway 
 2 genes, 1 drug (DrugBank), 8 diseases shown 		  [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 16  Kaposi sarcoma-associated herpesvirus infection 
 2 genes, 1 drug (DrugBank), 8 diseases shown 		  [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 17  Leishmaniasis 
 2 genes, 1 drug (DrugBank), 8 diseases shown 		  [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 18  Measles 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK1   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 19  Necroptosis 
 2 genes, 1 drug (DrugBank), 8 diseases shown 		  [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 20  NOD-like receptor signaling pathway 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK1   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 21  Osteoclast differentiation 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK1   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 22  Pancreatic cancer 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK1   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 23  Pathways in cancer 
 2 genes, 1 drug (DrugBank), 8 diseases shown 		  [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 24  PD-L1 expression and PD-1 checkpoint pathway in cancer 
 2 genes, 1 drug (DrugBank), 8 diseases shown 		  [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 25  PI3K-Akt signaling pathway 
 2 genes, 1 drug (DrugBank), 8 diseases shown 		  [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 26  Prolactin signaling pathway 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 27  Signaling pathways regulating pluripotency of stem cells 
 2 genes, 1 drug (DrugBank), 8 diseases shown 		  [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 28  Th1 and Th2 cell differentiation 
 2 genes, 1 drug (DrugBank), 8 diseases shown 		  [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 29  Th17 cell differentiation 
 2 genes, 1 drug (DrugBank), 8 diseases shown 		  [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 30  Toxoplasmosis 
 2 genes, 1 drug (DrugBank), 8 diseases shown 		  [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 31  Tuberculosis 
 2 genes, 1 drug (DrugBank), 8 diseases shown 		  [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 32  Viral carcinogenesis 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK1   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 

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