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 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

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55 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY
 On map, Yellow: Drug target, Red: Disease-related 
 KEGG GENES
 [Number of genes] 
 KEGG DRUG  DrugBank   Disease ID
 [Number of diseases] 
 1  Alzheimer disease 
 5 genes, 1 drug (DrugBank), 44 diseases shown 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 2  Amphetamine addiction 
 5 genes, 1 drug (DrugBank), 44 diseases shown 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 3  Amyotrophic lateral sclerosis (ALS) 
 5 genes, 1 drug (DrugBank), 44 diseases shown 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 4  Antifolate resistance 
 2 genes, 1 drug (DrugBank), 33 diseases shown 
 [2] DHFR, DHFR2   D00142   Methotrexate   [33] 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 5  Axon guidance 
 5 genes, 1 drug (DrugBank), 44 diseases shown 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 6  B cell receptor signaling pathway 
 5 genes, 1 drug (DrugBank), 44 diseases shown 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 7  C-type lectin receptor signaling pathway 
 5 genes, 1 drug (DrugBank), 44 diseases shown 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 8  Calcium signaling pathway 
 5 genes, 1 drug (DrugBank), 44 diseases shown 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 9  Cellular senescence 
 5 genes, 1 drug (DrugBank), 44 diseases shown 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 10  cGMP-PKG signaling pathway 
 5 genes, 1 drug (DrugBank), 44 diseases shown 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 11  Chagas disease (American trypanosomiasis) 
 2 genes, 1 drug (DrugBank), 7 diseases shown 
 [2] IFNGR1, IFNGR2   D00747   Interferon gamma-1b   [7] 65, 85, 90, 228, 299, 301, 326 
 12  Cytokine-cytokine receptor interaction 
 2 genes, 1 drug (DrugBank), 7 diseases shown 
 [2] IFNGR1, IFNGR2   D00747   Interferon gamma-1b   [7] 65, 85, 90, 228, 299, 301, 326 
 13  DNA replication 
 2 genes, 1 drug (DrugBank), 9 diseases shown 
 [2] POLA1, POLA2   D03546   Clofarabine   [9] 19, 20, 40, 46, 49, 60, 96, 234, 326 
 14  Dopaminergic synapse 
 3 genes, 1 drug (DrugBank), 44 diseases shown 
 [3] PPP3CA, PPP3CB, PPP3CC   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 15  Drug metabolism - other enzymes 
 1 gene, 2 drugs (DrugBank), 21 diseases shown 
 [1] RRM1   D03546   Clofarabine   [9] 19, 20, 40, 46, 49, 60, 96, 234, 326 
 D01907   Fludarabine   [17] 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 
 D07966 
 16  Endocrine and other factor-regulated calcium reabsorption 
 2 genes, 2 drugs (DrugBank), 9 diseases shown 
 [1] PTH1R   D05364   Parathyroid hormone   [3] 70, 235, 326 
 [1] VDR   D00129   Calcitriol   [8] 37, 46, 49, 66, 96, 158, 235, 326 
 17  Folate biosynthesis 
 2 genes, 1 drug (DrugBank), 33 diseases shown 
 [2] DHFR, DHFR2   D00142   Methotrexate   [33] 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 18  Glucagon signaling pathway 
 5 genes, 1 drug (DrugBank), 44 diseases shown 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 19  Glutamatergic synapse 
 5 genes, 1 drug (DrugBank), 44 diseases shown 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 20  Glutathione metabolism 
 1 gene, 2 drugs (DrugBank), 21 diseases shown 
 [1] RRM1   D03546   Clofarabine   [9] 19, 20, 40, 46, 49, 60, 96, 234, 326 
 D01907   Fludarabine   [17] 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 
 D07966 
 21  Herpes simplex virus 1 infection 
 2 genes, 1 drug (DrugBank), 7 diseases shown 
 [2] IFNGR1, IFNGR2   D00747   Interferon gamma-1b   [7] 65, 85, 90, 228, 299, 301, 326 
 22  HIF-1 signaling pathway 
 2 genes, 1 drug (DrugBank), 7 diseases shown 
 [2] IFNGR1, IFNGR2   D00747   Interferon gamma-1b   [7] 65, 85, 90, 228, 299, 301, 326 
 23  Human cytomegalovirus infection 
 5 genes, 1 drug (DrugBank), 44 diseases shown 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 24  Human immunodeficiency virus 1 infection 
 5 genes, 1 drug (DrugBank), 44 diseases shown 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 25  Human T-cell leukemia virus 1 infection 
 5 genes, 1 drug (DrugBank), 44 diseases shown 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 26  Inflammatory bowel disease (IBD) 
 2 genes, 1 drug (DrugBank), 7 diseases shown 
 [2] IFNGR1, IFNGR2   D00747   Interferon gamma-1b   [7] 65, 85, 90, 228, 299, 301, 326 
 27  Influenza A 
 2 genes, 1 drug (DrugBank), 7 diseases shown 
 [2] IFNGR1, IFNGR2   D00747   Interferon gamma-1b   [7] 65, 85, 90, 228, 299, 301, 326 
 28  JAK-STAT signaling pathway 
 2 genes, 1 drug (DrugBank), 7 diseases shown 
 [2] IFNGR1, IFNGR2   D00747   Interferon gamma-1b   [7] 65, 85, 90, 228, 299, 301, 326 
 29  Kaposi sarcoma-associated herpesvirus infection 
 6 genes, 2 drugs (DrugBank), 47 diseases shown 
 [1] IFNGR1   D00747   Interferon gamma-1b   [7] 65, 85, 90, 228, 299, 301, 326 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 30  Leishmaniasis 
 2 genes, 1 drug (DrugBank), 7 diseases shown 
 [2] IFNGR1, IFNGR2   D00747   Interferon gamma-1b   [7] 65, 85, 90, 228, 299, 301, 326 
 31  Long-term potentiation 
 5 genes, 1 drug (DrugBank), 44 diseases shown 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 32  MAPK signaling pathway 
 5 genes, 1 drug (DrugBank), 44 diseases shown 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 33  Metabolic pathways 
 3 genes, 3 drugs (DrugBank), 41 diseases shown 
 [2] DHFR, DHFR2   D00142   Methotrexate   [33] 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 [1] RRM1   D03546   Clofarabine   [9] 19, 20, 40, 46, 49, 60, 96, 234, 326 
 D01907   Fludarabine   [17] 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 
 D07966 
 34  Mineral absorption 
 1 gene, 1 drug (DrugBank), 8 diseases shown 
 [1] VDR   D00129   Calcitriol   [8] 37, 46, 49, 66, 96, 158, 235, 326 
 35  Natural killer cell mediated cytotoxicity 
 7 genes, 2 drugs (DrugBank), 47 diseases shown 
 [2] IFNGR1, IFNGR2   D00747   Interferon gamma-1b   [7] 65, 85, 90, 228, 299, 301, 326 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 36  Necroptosis 
 2 genes, 1 drug (DrugBank), 7 diseases shown 
 [2] IFNGR1, IFNGR2   D00747   Interferon gamma-1b   [7] 65, 85, 90, 228, 299, 301, 326 
 37  Neuroactive ligand-receptor interaction 
 2 genes, 1 drug (DrugBank), 3 diseases shown 
 [2] PTH1R, PTH2R   D05364   Parathyroid hormone   [3] 70, 235, 326 
 38  One carbon pool by folate 
 2 genes, 1 drug (DrugBank), 33 diseases shown 
 [2] DHFR, DHFR2   D00142   Methotrexate   [33] 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 39  Oocyte meiosis 
 5 genes, 1 drug (DrugBank), 44 diseases shown 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 40  Osteoclast differentiation 
 7 genes, 2 drugs (DrugBank), 47 diseases shown 
 [2] IFNGR1, IFNGR2   D00747   Interferon gamma-1b   [7] 65, 85, 90, 228, 299, 301, 326 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 41  Oxytocin signaling pathway 
 5 genes, 1 drug (DrugBank), 44 diseases shown 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 42  Parathyroid hormone synthesis, secretion and action 
 2 genes, 2 drugs (DrugBank), 9 diseases shown 
 [1] PTH1R   D05364   Parathyroid hormone   [3] 70, 235, 326 
 [1] VDR   D00129   Calcitriol   [8] 37, 46, 49, 66, 96, 158, 235, 326 
 43  Pathways in cancer 
 2 genes, 1 drug (DrugBank), 7 diseases shown 
 [2] IFNGR1, IFNGR2   D00747   Interferon gamma-1b   [7] 65, 85, 90, 228, 299, 301, 326 
 44  PD-L1 expression and PD-1 checkpoint pathway in cancer 
 7 genes, 2 drugs (DrugBank), 47 diseases shown 
 [2] IFNGR1, IFNGR2   D00747   Interferon gamma-1b   [7] 65, 85, 90, 228, 299, 301, 326 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 45  Purine metabolism 
 1 gene, 2 drugs (DrugBank), 21 diseases shown 
 [1] RRM1   D03546   Clofarabine   [9] 19, 20, 40, 46, 49, 60, 96, 234, 326 
 D01907   Fludarabine   [17] 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 
 D07966 
 46  Pyrimidine metabolism 
 1 gene, 2 drugs (DrugBank), 21 diseases shown 
 [1] RRM1   D03546   Clofarabine   [9] 19, 20, 40, 46, 49, 60, 96, 234, 326 
 D01907   Fludarabine   [17] 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 
 D07966 
 47  Renin secretion 
 5 genes, 1 drug (DrugBank), 44 diseases shown 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 48  Salmonella infection 
 2 genes, 1 drug (DrugBank), 7 diseases shown 
 [2] IFNGR1, IFNGR2   D00747   Interferon gamma-1b   [7] 65, 85, 90, 228, 299, 301, 326 
 49  T cell receptor signaling pathway 
 5 genes, 1 drug (DrugBank), 44 diseases shown 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 50  Th1 and Th2 cell differentiation 
 7 genes, 2 drugs (DrugBank), 47 diseases shown 
 [2] IFNGR1, IFNGR2   D00747   Interferon gamma-1b   [7] 65, 85, 90, 228, 299, 301, 326 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 51  Th17 cell differentiation 
 7 genes, 2 drugs (DrugBank), 47 diseases shown 
 [2] IFNGR1, IFNGR2   D00747   Interferon gamma-1b   [7] 65, 85, 90, 228, 299, 301, 326 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 52  Toxoplasmosis 
 2 genes, 1 drug (DrugBank), 7 diseases shown 
 [2] IFNGR1, IFNGR2   D00747   Interferon gamma-1b   [7] 65, 85, 90, 228, 299, 301, 326 
 53  Tuberculosis 
 8 genes, 3 drugs (DrugBank), 52 diseases shown 
 [2] IFNGR1, IFNGR2   D00747   Interferon gamma-1b   [7] 65, 85, 90, 228, 299, 301, 326 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 [1] VDR   D00129   Calcitriol   [8] 37, 46, 49, 66, 96, 158, 235, 326 
 54  VEGF signaling pathway 
 5 genes, 1 drug (DrugBank), 44 diseases shown 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 
 55  Wnt signaling pathway 
 5 genes, 1 drug (DrugBank), 44 diseases shown 
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   D00184   Ciclosporin   [44] 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 

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