Home    Back

 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

A    B    C    D    E    F    G    H     I     J    K    L    M    N    O    P    Q    R    S    T    U    V    W    X    Y    Z    other

149 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY * 
 On map, Yellow: Drug target, Red: Disease-related 		  KEGG GENES * 
 [Number of genes] 		  KEGG DRUG *   DrugBank   Disease ID * 
 [Number of diseases] 
 1  Acute myeloid leukemia 
 3 genes, 3 drugs (DrugBank), 40 diseases shown 		  [1] KIT   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 2  Adipocytokine signaling pathway 
 2 genes, 3 drugs (DrugBank), 56 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 3  African trypanosomiasis 
 1 gene, 2 drugs (DrugBank), 30 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 4  AGE-RAGE signaling pathway in diabetic complications 
 2 genes, 3 drugs (DrugBank), 31 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 5  Aldosterone-regulated sodium reabsorption 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 6  Allograft rejection 
 1 gene, 2 drugs (DrugBank), 30 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 7  Alzheimer disease 
 1 gene, 2 drugs (DrugBank), 30 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 8  Amoebiasis 
 2 genes, 3 drugs (DrugBank), 31 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 9  AMPK signaling pathway 
 2 genes, 2 drugs (DrugBank), 37 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 10  Amyotrophic lateral sclerosis (ALS) 
 1 gene, 2 drugs (DrugBank), 30 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 11  Antifolate resistance 
 3 genes, 3 drugs (DrugBank), 45 diseases shown 		  [2] DHFR, DHFR2   D00142   Methotrexate   [33] 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 12  Antigen processing and presentation 
 1 gene, 2 drugs (DrugBank), 30 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 13  Apelin signaling pathway 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 14  Apoptosis 
 2 genes, 3 drugs (DrugBank), 31 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 15  Arachidonic acid metabolism 
 2 genes, 1 drug (DrugBank), 13 diseases shown 		  [2] PTGS1, PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 16  Asthma 
 1 gene, 2 drugs (DrugBank), 30 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 17  Autophagy - animal 
 2 genes, 2 drugs (DrugBank), 37 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 18  Autophagy - other 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 19  Axon guidance 
 2 genes, 2 drugs (DrugBank), 13 diseases shown 		  [1] ABL1   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 20  B cell receptor signaling pathway 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 21  Bacterial invasion of epithelial cells 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 22  Breast cancer 
 3 genes, 3 drugs (DrugBank), 40 diseases shown 		  [1] KIT   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 23  C-type lectin receptor signaling pathway 
 3 genes, 4 drugs (DrugBank), 40 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 24  Calcium signaling pathway 
 2 genes, 2 drugs (DrugBank), 11 diseases shown 		  [1] HRH1   D00664   Cetirizine   [2] 13, 35 
 D07662 
 [1] PDGFRA   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 25  cAMP signaling pathway 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 26  Carbohydrate digestion and absorption 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 27  Cell cycle 
 1 gene, 1 drug (DrugBank), 11 diseases shown 		  [1] ABL1   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 28  Cellular senescence 
 2 genes, 2 drugs (DrugBank), 37 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 29  Central carbon metabolism in cancer 
 4 genes, 3 drugs (DrugBank), 40 diseases shown 		  [2] KIT, PDGFRA   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 30  Chagas disease (American trypanosomiasis) 
 2 genes, 3 drugs (DrugBank), 31 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 31  Chemical carcinogenesis 
 1 gene, 1 drug (DrugBank), 13 diseases shown 		  [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 32  Chemokine signaling pathway 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 33  Choline metabolism in cancer 
 3 genes, 3 drugs (DrugBank), 40 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PDGFRA   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 34  Cholinergic synapse 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 35  Chronic myeloid leukemia 
 2 genes, 2 drugs (DrugBank), 13 diseases shown 		  [1] ABL1   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 36  Colorectal cancer 
 2 genes, 2 drugs (DrugBank), 37 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 37  Cytokine-cytokine receptor interaction 
 3 genes, 3 drugs (DrugBank), 45 diseases shown 		  [1] CSF3R   D03235   Filgrastim   [28] 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 
 [2] LTA, TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 38  Dilated cardiomyopathy (DCM) 
 1 gene, 2 drugs (DrugBank), 30 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 39  Drug metabolism - other enzymes 
 2 genes, 2 drugs (DrugBank), 34 diseases shown 		  [2] IMPDH1, IMPDH2   D00752   Mycophenolate mofetil   [32] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 
 D05094 
 D05095 
 D05096   Mycophenolic acid   [34] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 
 40  EGFR tyrosine kinase inhibitor resistance 
 3 genes, 3 drugs (DrugBank), 40 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PDGFRA   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 41  Endocrine resistance 
 2 genes, 2 drugs (DrugBank), 37 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 42  Endocytosis 
 1 gene, 1 drug (DrugBank), 11 diseases shown 		  [1] PDGFRA   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 43  Endometrial cancer 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 44  Epstein-Barr virus infection 
 2 genes, 3 drugs (DrugBank), 31 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 45  ErbB signaling pathway 
 3 genes, 3 drugs (DrugBank), 40 diseases shown 		  [1] ABL1   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 46  Estrogen signaling pathway 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 47  Fc epsilon RI signaling pathway 
 2 genes, 3 drugs (DrugBank), 31 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 48  Fc gamma R-mediated phagocytosis 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 49  Fluid shear stress and atherosclerosis 
 2 genes, 3 drugs (DrugBank), 31 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 50  Focal adhesion 
 2 genes, 2 drugs (DrugBank), 13 diseases shown 		  [1] PDGFRA   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 51  Folate biosynthesis 
 2 genes, 1 drug (DrugBank), 33 diseases shown 		  [2] DHFR, DHFR2   D00142   Methotrexate   [33] 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 52  FoxO signaling pathway 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 53  Gap junction 
 1 gene, 1 drug (DrugBank), 11 diseases shown 		  [1] PDGFRA   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 54  Gastric cancer 
 2 genes, 2 drugs (DrugBank), 37 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 55  Glioma 
 3 genes, 3 drugs (DrugBank), 40 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PDGFRA   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 56  GnRH secretion 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 57  Graft-versus-host disease 
 1 gene, 2 drugs (DrugBank), 30 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 58  Growth hormone synthesis, secretion and action 
 2 genes, 2 drugs (DrugBank), 37 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 59  Hematopoietic cell lineage 
 4 genes, 6 drugs (DrugBank), 66 diseases shown 		  [1] CSF3R   D03235   Filgrastim   [28] 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 
 [1] KIT   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] MS4A1   D09314   Ofatumumab   [3] 13, 35, 46 
 D02994   Rituximab   [42] 11, 13, 14, 17, 35, 36, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 223, 229, 256, 271, 283, 284, 285, 288, 300, 331 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 60  Hepatitis B 
 2 genes, 3 drugs (DrugBank), 31 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 61  Hepatitis C 
 2 genes, 3 drugs (DrugBank), 31 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 62  Hepatocellular carcinoma 
 2 genes, 2 drugs (DrugBank), 37 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 63  Herpes simplex virus 1 infection 
 4 genes, 4 drugs (DrugBank), 56 diseases shown 		  [2] LTA, TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 64  HIF-1 signaling pathway 
 2 genes, 2 drugs (DrugBank), 37 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 65  Human cytomegalovirus infection 
 5 genes, 6 drugs (DrugBank), 61 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PDGFRA   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 66  Human immunodeficiency virus 1 infection 
 3 genes, 4 drugs (DrugBank), 56 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 67  Human papillomavirus infection 
 4 genes, 5 drugs (DrugBank), 60 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 68  Human T-cell leukemia virus 1 infection 
 3 genes, 3 drugs (DrugBank), 31 diseases shown 		  [2] LTA, TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 69  Hypertrophic cardiomyopathy (HCM) 
 1 gene, 2 drugs (DrugBank), 30 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 70  IL-17 signaling pathway 
 2 genes, 3 drugs (DrugBank), 39 diseases shown 		  [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 71  Inflammatory bowel disease (IBD) 
 1 gene, 2 drugs (DrugBank), 30 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 72  Inflammatory mediator regulation of TRP channels 
 2 genes, 2 drugs (DrugBank), 4 diseases shown 		  [1] HRH1   D00664   Cetirizine   [2] 13, 35 
 D07662 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 73  Influenza A 
 2 genes, 3 drugs (DrugBank), 31 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 74  Inositol phosphate metabolism 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 75  Insulin resistance 
 3 genes, 4 drugs (DrugBank), 56 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 76  Insulin signaling pathway 
 2 genes, 2 drugs (DrugBank), 37 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 77  JAK-STAT signaling pathway 
 4 genes, 4 drugs (DrugBank), 51 diseases shown 		  [1] CSF3R   D03235   Filgrastim   [28] 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 
 [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PDGFRA   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 78  Kaposi sarcoma-associated herpesvirus infection 
 3 genes, 3 drugs (DrugBank), 42 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 79  Legionellosis 
 1 gene, 2 drugs (DrugBank), 30 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 80  Leishmaniasis 
 2 genes, 3 drugs (DrugBank), 39 diseases shown 		  [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 81  Leukocyte transendothelial migration 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 82  Longevity regulating pathway 
 2 genes, 2 drugs (DrugBank), 37 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 83  Longevity regulating pathway - multiple species 
 2 genes, 2 drugs (DrugBank), 37 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 84  Malaria 
 1 gene, 2 drugs (DrugBank), 30 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 85  MAPK signaling pathway 
 3 genes, 3 drugs (DrugBank), 36 diseases shown 		  [2] KIT, PDGFRA   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 86  Measles 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 87  Melanogenesis 
 1 gene, 1 drug (DrugBank), 11 diseases shown 		  [1] KIT   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 88  Melanoma 
 2 genes, 2 drugs (DrugBank), 13 diseases shown 		  [1] PDGFRA   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 89  Metabolic pathways 
 7 genes, 5 drugs (DrugBank), 54 diseases shown 		  [2] DHFR, DHFR2   D00142   Methotrexate   [33] 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 [2] IMPDH1, IMPDH2   D00752   Mycophenolate mofetil   [32] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 
 D05094 
 D05095 
 D05096   Mycophenolic acid   [34] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [2] PTGS1, PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 90  MicroRNAs in cancer 
 5 genes, 4 drugs (DrugBank), 45 diseases shown 		  [2] ABL1, PDGFRA   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 91  mTOR signaling pathway 
 3 genes, 4 drugs (DrugBank), 56 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 92  Natural killer cell mediated cytotoxicity 
 2 genes, 3 drugs (DrugBank), 31 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 93  Necroptosis 
 1 gene, 2 drugs (DrugBank), 30 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 94  Neuroactive ligand-receptor interaction 
 2 genes, 7 drugs (DrugBank), 64 diseases shown 		  [1] HRH1   D00664   Cetirizine   [2] 13, 35 
 D07662 
 [1] NR3C1   D00292   Dexamethasone   [20] 13, 16, 28, 35, 46, 53, 63, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 222, 296, 299 
 D00975 
 D01510 
 D01615 
 D01632 
 D01948 
 D02174 
 D02591 
 D02592 
 D00407   Methylprednisolone   [36] 2, 13, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 145, 164, 220, 222, 224, 271, 283, 284, 285, 296 
 D00751 
 D00979 
 D05000 
 D05001 
 D05002 
 D00472   Prednisolone   [38] 11, 13, 25, 26, 35, 38, 39, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 
 D00980 
 D00981 
 D00982 
 D01239 
 D01998 
 D02156 
 D03301 
 D00473   Prednisone   [44] 2, 11, 13, 14, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 95, 96, 97, 113, 145, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 
 D08416   Prednisone acetate   [6] 35, 40, 41, 49, 162, 224 
 D00385   Triamcinolone   [18] 6, 10, 13, 35, 40, 41, 42, 43, 44, 45, 46, 56, 70, 90, 96, 97, 226, 298 
 D00983 
 D00984 
 D00985 
 D06216 
 95  Neurotrophin signaling pathway 
 2 genes, 2 drugs (DrugBank), 13 diseases shown 		  [1] ABL1   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 96  NF-kappa B signaling pathway 
 3 genes, 3 drugs (DrugBank), 39 diseases shown 		  [2] LTA, TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 97  NOD-like receptor signaling pathway 
 1 gene, 2 drugs (DrugBank), 30 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 98  Non-alcoholic fatty liver disease (NAFLD) 
 2 genes, 3 drugs (DrugBank), 31 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 99  Non-small cell lung cancer 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 100  One carbon pool by folate 
 2 genes, 1 drug (DrugBank), 33 diseases shown 		  [2] DHFR, DHFR2   D00142   Methotrexate   [33] 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 101  Osteoclast differentiation 
 2 genes, 3 drugs (DrugBank), 31 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 102  Ovarian steroidogenesis 
 1 gene, 1 drug (DrugBank), 13 diseases shown 		  [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 103  Oxytocin signaling pathway 
 1 gene, 1 drug (DrugBank), 13 diseases shown 		  [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 104  Pancreatic cancer 
 2 genes, 2 drugs (DrugBank), 37 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 105  Pathogenic Escherichia coli infection 
 2 genes, 3 drugs (DrugBank), 36 diseases shown 		  [1] ABL1   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 106  Pathways in cancer 
 7 genes, 5 drugs (DrugBank), 55 diseases shown 		  [3] ABL1, KIT, PDGFRA   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] CSF3R   D03235   Filgrastim   [28] 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 
 [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 107  PD-L1 expression and PD-1 checkpoint pathway in cancer 
 2 genes, 2 drugs (DrugBank), 37 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 108  Pertussis 
 1 gene, 2 drugs (DrugBank), 30 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 109  Phosphatidylinositol signaling system 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 110  Phospholipase D signaling pathway 
 4 genes, 3 drugs (DrugBank), 40 diseases shown 		  [2] KIT, PDGFRA   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 111  PI3K-Akt signaling pathway 
 5 genes, 4 drugs (DrugBank), 51 diseases shown 		  [1] CSF3R   D03235   Filgrastim   [28] 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 
 [2] KIT, PDGFRA   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 112  Platelet activation 
 2 genes, 2 drugs (DrugBank), 15 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] PTGS1   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 113  Platinum drug resistance 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 114  Progesterone-mediated oocyte maturation 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 115  Prolactin signaling pathway 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 116  Prostate cancer 
 3 genes, 3 drugs (DrugBank), 40 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PDGFRA   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 117  Proteoglycans in cancer 
 3 genes, 4 drugs (DrugBank), 56 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 118  Purine metabolism 
 2 genes, 2 drugs (DrugBank), 34 diseases shown 		  [2] IMPDH1, IMPDH2   D00752   Mycophenolate mofetil   [32] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 
 D05094 
 D05095 
 D05096   Mycophenolic acid   [34] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 
 119  Rap1 signaling pathway 
 3 genes, 2 drugs (DrugBank), 13 diseases shown 		  [2] KIT, PDGFRA   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 120  Ras signaling pathway 
 4 genes, 2 drugs (DrugBank), 13 diseases shown 		  [3] ABL1, KIT, PDGFRA   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 121  Regulation of actin cytoskeleton 
 2 genes, 2 drugs (DrugBank), 13 diseases shown 		  [1] PDGFRA   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 122  Regulation of lipolysis in adipocytes 
 3 genes, 2 drugs (DrugBank), 15 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [2] PTGS1, PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 123  Relaxin signaling pathway 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 124  Renal cell carcinoma 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 125  Retrograde endocannabinoid signaling 
 1 gene, 1 drug (DrugBank), 13 diseases shown 		  [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 126  Rheumatoid arthritis 
 1 gene, 2 drugs (DrugBank), 30 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 127  RIG-I-like receptor signaling pathway 
 1 gene, 2 drugs (DrugBank), 30 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 128  Serotonergic synapse 
 2 genes, 1 drug (DrugBank), 13 diseases shown 		  [2] PTGS1, PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 129  Shigellosis 
 4 genes, 5 drugs (DrugBank), 57 diseases shown 		  [1] ABL1   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 130  Signaling pathways regulating pluripotency of stem cells 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 131  Small cell lung cancer 
 2 genes, 2 drugs (DrugBank), 15 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 132  Sphingolipid signaling pathway 
 2 genes, 3 drugs (DrugBank), 31 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 133  Systemic lupus erythematosus 
 1 gene, 2 drugs (DrugBank), 30 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 134  T cell receptor signaling pathway 
 2 genes, 3 drugs (DrugBank), 31 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 135  TGF-beta signaling pathway 
 1 gene, 2 drugs (DrugBank), 30 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 136  Th17 cell differentiation 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 137  Thermogenesis 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 138  Thyroid hormone signaling pathway 
 2 genes, 2 drugs (DrugBank), 37 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 139  TNF signaling pathway 
 4 genes, 4 drugs (DrugBank), 40 diseases shown 		  [2] LTA, TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 140  Toll-like receptor signaling pathway 
 2 genes, 3 drugs (DrugBank), 31 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 141  Toxoplasmosis 
 1 gene, 2 drugs (DrugBank), 30 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 142  Tuberculosis 
 1 gene, 2 drugs (DrugBank), 30 diseases shown 		  [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 143  Type I diabetes mellitus 
 2 genes, 2 drugs (DrugBank), 30 diseases shown 		  [2] LTA, TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 144  Type II diabetes mellitus 
 3 genes, 4 drugs (DrugBank), 56 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 145  VEGF signaling pathway 
 2 genes, 2 drugs (DrugBank), 15 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] PTGS2   D00217   Acetaminophen   [13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 
 146  Viral carcinogenesis 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 147  Viral myocarditis 
 1 gene, 1 drug (DrugBank), 11 diseases shown 		  [1] ABL1   D01441   Imatinib   [11] 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 
 D08066 
 148  Viral protein interaction with cytokine and cytokine receptor 
 2 genes, 2 drugs (DrugBank), 30 diseases shown 		  [2] LTA, TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 149  Yersinia infection 
 2 genes, 3 drugs (DrugBank), 31 diseases shown 		  [1] PIK3CD   D11437   Parsaclisib   [3] 35, 53, 61 
 [1] TNF   D00742   Etanercept   [15] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 
 D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 

Back to top