No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * [Number of genes] |
KEGG DRUG * |
DrugBank |
Disease ID * [Number of diseases] |
1 | ABC transporters 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] ABCC8 |
D00594 |
Repaglinide |
[2] 6, 299 |
2 | Acute myeloid leukemia 1 gene, 2 drugs (DrugBank), 10 diseases shown |
[1] KIT |
D10229 |
Masitinib |
[6] 2, 5, 6, 13, 46, 96 |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
3 | Adherens junction 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
4 | Adipocytokine signaling pathway 2 genes, 1 drug (DrugBank), 17 diseases shown |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
5 | Adrenergic signaling in cardiomyocytes 14 genes, 16 drugs (DrugBank), 27 diseases shown |
[1] ADRA1A |
D01965 |
Silodosin |
[2] 6, 13 |
[3] ADRA1A, ADRA1B, ADRA1D |
D02268 |
Ergoloid mesylate |
[1] 6 |
D01307 |
Midodrine |
[3] 6, 17, 58 |
D08220 |
D00610 |
Terazosin |
[1] 6 |
D08569 |
[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 |
D00255 |
Carvedilol |
[4] 6, 57, 86, 113 |
D03415 |
D02349 |
Dipivefrin |
[1] 6 |
D01277 |
Droxidopa |
[3] 5, 6, 17 |
D00095 |
Epinephrine |
[9] 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
[2] ADRB1, ADRB2 |
D00483 |
Propranolol |
[5] 6, 158, 167, 227, 278 |
D08443 |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
[5] CACNA1C, CACNA1D, CACNA1F, CACNA1S, SCN5A |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 |
D00332 |
Gabapentin |
[7] 6, 13, 19, 70, 97, 226, 298 |
[1] SCN5A |
D00638 |
Flecainide |
[1] 6 |
D07962 |
D00358 |
Lidocaine |
[10] 6, 13, 46, 84, 86, 97, 168, 226, 231, 256 |
D02086 |
D08127 |
D01768 |
Oxybuprocaine |
[1] 6 |
D08319 |
D00538 |
Zonisamide |
[1] 6 |
6 | Alcoholism 12 genes, 38 drugs (DrugBank), 32 diseases shown |
[1] ADORA2A |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
D04641 |
Istradefylline |
[1] 6 |
D09717 |
Preladenant |
[1] 6 |
D10174 |
Tozadenant |
[1] 6 |
[1] DDC |
D03082 |
Benserazide |
[1] 6 |
D00558 |
Carbidopa |
[8] 2, 4, 6, 13, 17, 90, 164, 201 |
[1] DRD1 |
D11431 |
Tavapadon |
[1] 6 |
[2] DRD1, DRD2 |
D02004 |
Apomorphine |
[1] 6 |
D07460 |
D00633 |
Dopamine |
[3] 6, 7, 74 |
D07870 |
D00059 |
Levodopa |
[7] 2, 4, 6, 17, 90, 164, 201 |
D00502 |
Pergolide |
[1] 6 |
D08339 |
[1] DRD2 |
D01164 |
Aripiprazole |
[2] 6, 206 |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00702 |
Buspirone |
[2] 6, 51 |
D07593 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
D01745 |
Domperidone |
[5] 6, 13, 17, 51, 230 |
D07868 |
D01462 |
Lisuride |
[2] 6, 86 |
D08132 |
D07309 |
Melperone |
[1] 6 |
D09397 |
Pardoprunox |
[1] 6 |
D07305 |
Piribedil |
[1] 6 |
D00559 |
Pramipexole |
[2] 2, 6 |
D05575 |
D09953 |
Pridopidine |
[2] 6, 8 |
D00458 |
Quetiapine |
[2] 6, 13 |
D08456 |
D00784 |
Ropinirole |
[3] 6, 74, 309 |
D08489 |
D05768 |
Rotigotine |
[1] 6 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D02780 |
Acamprosate |
[2] 6, 206 |
D07058 |
D00777 |
Amantadine |
[4] 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
[1] MAOA |
D02561 |
Moclobemide |
[1] 6 |
[2] MAOA, MAOB |
D02579 |
Iproniazid |
[1] 6 |
D00505 |
Phenelzine |
[1] 6 |
D08349 |
[1] MAOB |
D02562 |
Rasagiline |
[4] 2, 5, 6, 17 |
D08469 |
D10829 |
D10158 |
Safinamide |
[2] 6, 17 |
D00785 |
Selegiline |
[1] 6 |
D03731 |
[1] SLC6A3 |
D03215 |
Armodafinil |
[3] 6, 13, 84 |
D01296 |
Methylphenidate |
[7] 6, 13, 34, 84, 113, 179, 206 |
D04999 |
7 | Aldosterone synthesis and secretion 8 genes, 4 drugs (DrugBank), 10 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[3] CACNA1G, CACNA1H, CACNA1I |
D00538 |
Zonisamide |
[1] 6 |
[1] PDE2A |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
8 | Aldosterone-regulated sodium reabsorption 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] NR3C2 |
D00986 |
Fludrocortisone |
[3] 6, 17, 81 |
D07967 |
9 | Alzheimer disease 9 genes, 7 drugs (DrugBank), 19 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D02780 |
Acamprosate |
[2] 6, 206 |
D07058 |
D00777 |
Amantadine |
[4] 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
10 | Amphetamine addiction 16 genes, 24 drugs (DrugBank), 30 diseases shown |
[2] CACNA1C, CACNA1D |
D00349 |
Isradipine |
[1] 6 |
[6] CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[1] DDC |
D03082 |
Benserazide |
[1] 6 |
D00558 |
Carbidopa |
[8] 2, 4, 6, 13, 17, 90, 164, 201 |
[1] DRD1 |
D02004 |
Apomorphine |
[1] 6 |
D07460 |
D00633 |
Dopamine |
[3] 6, 7, 74 |
D07870 |
D00059 |
Levodopa |
[7] 2, 4, 6, 17, 90, 164, 201 |
D00502 |
Pergolide |
[1] 6 |
D08339 |
D11431 |
Tavapadon |
[1] 6 |
[4] GRIA1, GRIA2, GRIA3, GRIA4 |
D08964 |
Perampanel |
[3] 2, 6, 144 |
D02696 |
Talampanel |
[2] 2, 6 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D02780 |
Acamprosate |
[2] 6, 206 |
D07058 |
D00777 |
Amantadine |
[4] 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
[1] MAOA |
D02561 |
Moclobemide |
[1] 6 |
[2] MAOA, MAOB |
D02579 |
Iproniazid |
[1] 6 |
D00505 |
Phenelzine |
[1] 6 |
D08349 |
[1] MAOB |
D02562 |
Rasagiline |
[4] 2, 5, 6, 17 |
D08469 |
D10829 |
D10158 |
Safinamide |
[2] 6, 17 |
D00785 |
Selegiline |
[1] 6 |
D03731 |
[1] SLC6A3 |
D03215 |
Armodafinil |
[3] 6, 13, 84 |
D01296 |
Methylphenidate |
[7] 6, 13, 34, 84, 113, 179, 206 |
D04999 |
11 | AMPK signaling pathway 5 genes, 13 drugs (DrugBank), 46 diseases shown |
[1] ADRA1A |
D00255 |
Carvedilol |
[4] 6, 57, 86, 113 |
D03415 |
D02349 |
Dipivefrin |
[1] 6 |
D01277 |
Droxidopa |
[3] 5, 6, 17 |
D00095 |
Epinephrine |
[9] 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
D02268 |
Ergoloid mesylate |
[1] 6 |
D01307 |
Midodrine |
[3] 6, 17, 58 |
D08220 |
D01965 |
Silodosin |
[2] 6, 13 |
D00610 |
Terazosin |
[1] 6 |
D08569 |
[1] HMGCR |
D00359 |
Lovastatin |
[10] 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 |
D01915 |
Rosuvastatin |
[8] 6, 46, 49, 51, 79, 96, 271, 299 |
D08492 |
D00434 |
Simvastatin |
[19] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
12 | Amyotrophic lateral sclerosis (ALS) 7 genes, 8 drugs (DrugBank), 19 diseases shown |
[2] GRIA1, GRIA2 |
D08964 |
Perampanel |
[3] 2, 6, 144 |
D02696 |
Talampanel |
[2] 2, 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D02780 |
Acamprosate |
[2] 6, 206 |
D07058 |
D00777 |
Amantadine |
[4] 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
13 | Apelin signaling pathway 3 genes, 2 drugs (DrugBank), 21 diseases shown |
[1] PDE3B |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
14 | Arachidonic acid metabolism 2 genes, 1 drug (DrugBank), 13 diseases shown |
[2] PTGS1, PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
15 | Arginine and proline metabolism 2 genes, 6 drugs (DrugBank), 4 diseases shown |
[1] MAOA |
D02561 |
Moclobemide |
[1] 6 |
[2] MAOA, MAOB |
D02579 |
Iproniazid |
[1] 6 |
D00505 |
Phenelzine |
[1] 6 |
D08349 |
[1] MAOB |
D02562 |
Rasagiline |
[4] 2, 5, 6, 17 |
D08469 |
D10829 |
D10158 |
Safinamide |
[2] 6, 17 |
D00785 |
Selegiline |
[1] 6 |
D03731 |
16 | Arrhythmogenic right ventricular cardiomyopathy (ARVC) 8 genes, 3 drugs (DrugBank), 11 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 |
D00332 |
Gabapentin |
[7] 6, 13, 19, 70, 97, 226, 298 |
17 | Autophagy - animal 2 genes, 1 drug (DrugBank), 17 diseases shown |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
18 | Axon guidance 2 genes, 2 drugs (DrugBank), 6 diseases shown |
[1] ABL1 |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
[2] ABL1, SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
19 | Bacterial invasion of epithelial cells 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
20 | Bile secretion 3 genes, 5 drugs (DrugBank), 36 diseases shown |
[1] CA2 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[1] HMGCR |
D00359 |
Lovastatin |
[10] 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 |
D01915 |
Rosuvastatin |
[8] 6, 46, 49, 51, 79, 96, 271, 299 |
D08492 |
D00434 |
Simvastatin |
[19] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
[1] NR1H4 |
D00734 |
Ursodeoxycholic acid |
[12] 6, 8, 20, 67, 84, 93, 94, 95, 96, 97, 234, 299 |
21 | Bladder cancer 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
22 | Breast cancer 1 gene, 2 drugs (DrugBank), 10 diseases shown |
[1] KIT |
D10229 |
Masitinib |
[6] 2, 5, 6, 13, 46, 96 |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
23 | C-type lectin receptor signaling pathway 2 genes, 2 drugs (DrugBank), 14 diseases shown |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
24 | Caffeine metabolism 1 gene, 2 drugs (DrugBank), 8 diseases shown |
[1] XDH |
D00224 |
Allopurinol |
[6] 6, 46, 57, 66, 96, 97 |
D01206 |
Febuxostat |
[3] 2, 6, 13 |
25 | Calcium signaling pathway 32 genes, 46 drugs (DrugBank), 44 diseases shown |
[1] ADORA2A |
D04641 |
Istradefylline |
[1] 6 |
D09717 |
Preladenant |
[1] 6 |
D10174 |
Tozadenant |
[1] 6 |
[2] ADORA2A, PDE1B |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
[1] ADRA1A |
D01965 |
Silodosin |
[2] 6, 13 |
[3] ADRA1A, ADRA1B, ADRA1D |
D02268 |
Ergoloid mesylate |
[1] 6 |
D01307 |
Midodrine |
[3] 6, 17, 58 |
D08220 |
D00610 |
Terazosin |
[1] 6 |
D08569 |
[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 |
D00255 |
Carvedilol |
[4] 6, 57, 86, 113 |
D03415 |
[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 |
D02349 |
Dipivefrin |
[1] 6 |
D01277 |
Droxidopa |
[3] 5, 6, 17 |
D00095 |
Epinephrine |
[9] 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
[3] ADRB1, ADRB2, ADRB3 |
D00483 |
Propranolol |
[5] 6, 158, 167, 227, 278 |
D08443 |
[1] ADRB3 |
D09535 |
Mirabegron |
[3] 6, 13, 226 |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[3] CACNA1G, CACNA1H, CACNA1I |
D00538 |
Zonisamide |
[1] 6 |
[4] CHRM1, CHRM2, CHRM3, CHRM5 |
D02212 |
Ipratropium |
[2] 6, 86 |
D00465 |
Oxybutynin |
[1] 6 |
D00722 |
D00787 |
Trihexyphenidyl |
[2] 5, 6 |
D08638 |
D00397 |
Tropicamide |
[2] 6, 19 |
[2] CHRM2, CHRM3 |
D07226 |
Fesoterodine |
[1] 6 |
D00525 |
Pilocarpine |
[3] 6, 53, 299 |
D02200 |
D05478 |
[1] CHRM3 |
D01699 |
Darifenacin |
[2] 6, 13 |
D03654 |
D00540 |
Glycopyrronium |
[1] 6 |
D10938 |
D01269 |
Solifenacin |
[1] 6 |
D08522 |
[1] CHRNA7 |
D03365 |
Nicotine |
[2] 6, 84 |
D05156 |
D05157 |
[1] DRD1 |
D02004 |
Apomorphine |
[1] 6 |
D07460 |
D00502 |
Pergolide |
[1] 6 |
D08339 |
[2] DRD1, DRD5 |
D00633 |
Dopamine |
[3] 6, 7, 74 |
D07870 |
D00059 |
Levodopa |
[7] 2, 4, 6, 17, 90, 164, 201 |
D11431 |
Tavapadon |
[1] 6 |
[4] GRIN1, GRIN2A, GRIN2C, GRIN2D |
D02780 |
Acamprosate |
[2] 6, 206 |
D07058 |
D00777 |
Amantadine |
[4] 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
[1] HRH1 |
D00814 |
Doxepin |
[1] 6 |
D07875 |
D00364 |
Loratadine |
[3] 6, 13, 46 |
[1] HRH2 |
D00318 |
Famotidine |
[3] 6, 46, 86 |
[1] HTR2A |
D01164 |
Aripiprazole |
[2] 6, 206 |
D09645 |
Nelotanserin |
[1] 6 |
D00458 |
Quetiapine |
[2] 6, 13 |
D08456 |
[2] HTR2A, HTR2C |
D00283 |
Clozapine |
[1] 6 |
[1] HTR2C |
D02578 |
Agomelatine |
[1] 6 |
[2] PDGFRA, PDGFRB |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
26 | cAMP signaling pathway 32 genes, 48 drugs (DrugBank), 45 diseases shown |
[8] ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
[1] ADORA2A |
D04641 |
Istradefylline |
[1] 6 |
D09717 |
Preladenant |
[1] 6 |
D10174 |
Tozadenant |
[1] 6 |
[2] ADRB1, ADRB2 |
D00255 |
Carvedilol |
[4] 6, 57, 86, 113 |
D03415 |
D02349 |
Dipivefrin |
[1] 6 |
D01277 |
Droxidopa |
[3] 5, 6, 17 |
D00095 |
Epinephrine |
[9] 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
D00483 |
Propranolol |
[5] 6, 158, 167, 227, 278 |
D08443 |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
[8] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GRIA1, GRIA2, GRIA3, GRIA4 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[2] CHRM1, CHRM2 |
D02212 |
Ipratropium |
[2] 6, 86 |
D00465 |
Oxybutynin |
[1] 6 |
D00722 |
D00787 |
Trihexyphenidyl |
[2] 5, 6 |
D08638 |
D00397 |
Tropicamide |
[2] 6, 19 |
[1] CHRM2 |
D07226 |
Fesoterodine |
[1] 6 |
D00525 |
Pilocarpine |
[3] 6, 53, 299 |
D02200 |
D05478 |
[2] DRD1, DRD2 |
D02004 |
Apomorphine |
[1] 6 |
D07460 |
D00502 |
Pergolide |
[1] 6 |
D08339 |
[3] DRD1, DRD2, DRD5 |
D00633 |
Dopamine |
[3] 6, 7, 74 |
D07870 |
D00059 |
Levodopa |
[7] 2, 4, 6, 17, 90, 164, 201 |
[2] DRD1, DRD5 |
D11431 |
Tavapadon |
[1] 6 |
[1] DRD2 |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
D01745 |
Domperidone |
[5] 6, 13, 17, 51, 230 |
D07868 |
D01462 |
Lisuride |
[2] 6, 86 |
D08132 |
D07309 |
Melperone |
[1] 6 |
D07305 |
Piribedil |
[1] 6 |
D00559 |
Pramipexole |
[2] 2, 6 |
D05575 |
D09953 |
Pridopidine |
[2] 6, 8 |
D00458 |
Quetiapine |
[2] 6, 13 |
D08456 |
D00784 |
Ropinirole |
[3] 6, 74, 309 |
D08489 |
D05768 |
Rotigotine |
[1] 6 |
[2] DRD2, HTR1A |
D01164 |
Aripiprazole |
[2] 6, 206 |
D00702 |
Buspirone |
[2] 6, 51 |
D07593 |
D09397 |
Pardoprunox |
[1] 6 |
[1] GLP1R |
D04121 |
Exenatide |
[3] 6, 193, 233 |
D06404 |
Liraglutide |
[3] 6, 75, 193 |
D09729 |
Lixisenatide |
[1] 6 |
D10025 |
Semaglutide |
[1] 6 |
[4] GRIA1, GRIA2, GRIA3, GRIA4 |
D08964 |
Perampanel |
[3] 2, 6, 144 |
D02696 |
Talampanel |
[2] 2, 6 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D02780 |
Acamprosate |
[2] 6, 206 |
D07058 |
D00777 |
Amantadine |
[4] 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
[2] HTR1B, HTR1D |
D00415 |
Zolmitriptan |
[1] 6 |
27 | Carbohydrate digestion and absorption 1 gene, 2 drugs (DrugBank), 5 diseases shown |
[1] CACNA1D |
D00349 |
Isradipine |
[1] 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
28 | Cardiac muscle contraction 8 genes, 3 drugs (DrugBank), 11 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 |
D00332 |
Gabapentin |
[7] 6, 13, 19, 70, 97, 226, 298 |
29 | Cell cycle 1 gene, 2 drugs (DrugBank), 6 diseases shown |
[1] ABL1 |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
D09664 |
Saracatinib |
[2] 6, 89 |
30 | Cellular senescence 1 gene, 2 drugs (DrugBank), 5 diseases shown |
[1] CACNA1D |
D00349 |
Isradipine |
[1] 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
31 | Central carbon metabolism in cancer 3 genes, 2 drugs (DrugBank), 10 diseases shown |
[1] KIT |
D10229 |
Masitinib |
[6] 2, 5, 6, 13, 46, 96 |
[3] KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
32 | cGMP-PKG signaling pathway 19 genes, 22 drugs (DrugBank), 50 diseases shown |
[5] ADORA1, PDE2A, PDE3A, PDE3B, PDE5A |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
[1] ADRA1A |
D01965 |
Silodosin |
[2] 6, 13 |
[3] ADRA1A, ADRA1B, ADRA1D |
D01307 |
Midodrine |
[3] 6, 17, 58 |
D08220 |
D00610 |
Terazosin |
[1] 6 |
D08569 |
[6] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C |
D02268 |
Ergoloid mesylate |
[1] 6 |
[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 |
D02349 |
Dipivefrin |
[1] 6 |
D01277 |
Droxidopa |
[3] 5, 6, 17 |
D00095 |
Epinephrine |
[9] 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 |
D00255 |
Carvedilol |
[4] 6, 57, 86, 113 |
D03415 |
[3] ADRA2A, ADRA2B, ADRA2C |
D00281 |
Clonidine |
[2] 6, 78 |
D00604 |
D00283 |
Clozapine |
[1] 6 |
D00514 |
Dexmedetomidine |
[11] 2, 4, 6, 21, 34, 70, 113, 212, 215, 226, 280 |
D01205 |
[3] ADRB1, ADRB2, ADRB3 |
D00483 |
Propranolol |
[5] 6, 158, 167, 227, 278 |
D08443 |
[1] ADRB3 |
D09535 |
Mirabegron |
[3] 6, 13, 226 |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[1] OPRD1 |
D05111 |
Nalmefene |
[1] 6 |
D01340 |
Naloxone |
[2] 6, 226 |
D08249 |
D02095 |
Naltrexone |
[11] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 |
D05113 |
D03783 |
Oxycodone |
[7] 6, 13, 46, 70, 226, 231, 298 |
D05312 |
D05462 |
[1] PDE5A |
D02229 |
Sildenafil |
[16] 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
D08514 |
D02008 |
Tadalafil |
[6] 6, 51, 75, 84, 86, 113 |
33 | Chemical carcinogenesis 2 genes, 2 drugs (DrugBank), 14 diseases shown |
[1] CHRNA7 |
D03365 |
Nicotine |
[2] 6, 84 |
D05156 |
D05157 |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
34 | Chemokine signaling pathway 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
35 | Choline metabolism in cancer 2 genes, 1 drug (DrugBank), 5 diseases shown |
[2] PDGFRA, PDGFRB |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
36 | Cholinergic synapse 16 genes, 17 drugs (DrugBank), 21 diseases shown |
[1] ACHE |
D00670 |
Donepezil |
[9] 5, 6, 13, 46, 78, 124, 127, 156, 206 |
D07869 |
D02173 |
Galantamine |
[2] 6, 127 |
D04292 |
D00487 |
Pyridostigmine |
[4] 3, 6, 11, 256 |
D02558 |
Rivastigmine |
[3] 5, 6, 13 |
D03822 |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 |
D02212 |
Ipratropium |
[2] 6, 86 |
D00465 |
Oxybutynin |
[1] 6 |
D00722 |
D00787 |
Trihexyphenidyl |
[2] 5, 6 |
D08638 |
D00397 |
Tropicamide |
[2] 6, 19 |
[2] CHRM2, CHRM3 |
D07226 |
Fesoterodine |
[1] 6 |
D00525 |
Pilocarpine |
[3] 6, 53, 299 |
D02200 |
D05478 |
[1] CHRM3 |
D01699 |
Darifenacin |
[2] 6, 13 |
D03654 |
D00540 |
Glycopyrronium |
[1] 6 |
D10938 |
D01269 |
Solifenacin |
[1] 6 |
D08522 |
[6] CHRNA3, CHRNA4, CHRNA6, CHRNA7, CHRNB2, CHRNB4 |
D03365 |
Nicotine |
[2] 6, 84 |
D05156 |
D05157 |
[2] CHRNA4, CHRNB2 |
D08669 |
Varenicline |
[2] 6, 18 |
37 | Chronic myeloid leukemia 1 gene, 2 drugs (DrugBank), 6 diseases shown |
[1] ABL1 |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
D09664 |
Saracatinib |
[2] 6, 89 |
38 | Circadian entrainment 16 genes, 13 drugs (DrugBank), 21 diseases shown |
[2] CACNA1C, CACNA1D |
D00349 |
Isradipine |
[1] 6 |
[6] CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[3] CACNA1G, CACNA1H, CACNA1I |
D00538 |
Zonisamide |
[1] 6 |
[4] GRIA1, GRIA2, GRIA3, GRIA4 |
D08964 |
Perampanel |
[3] 2, 6, 144 |
D02696 |
Talampanel |
[2] 2, 6 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D02780 |
Acamprosate |
[2] 6, 206 |
D07058 |
D00777 |
Amantadine |
[4] 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
[2] MTNR1A, MTNR1B |
D02578 |
Agomelatine |
[1] 6 |
D08170 |
Melatonin |
[8] 6, 13, 46, 49, 90, 97, 144, 202 |
D02689 |
Ramelteon |
[3] 6, 8, 46 |
39 | Circadian rhythm 2 genes, 1 drug (DrugBank), 17 diseases shown |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
40 | Cocaine addiction 12 genes, 37 drugs (DrugBank), 35 diseases shown |
[1] DDC |
D03082 |
Benserazide |
[1] 6 |
D00558 |
Carbidopa |
[8] 2, 4, 6, 13, 17, 90, 164, 201 |
[1] DRD1 |
D11431 |
Tavapadon |
[1] 6 |
[2] DRD1, DRD2 |
D02004 |
Apomorphine |
[1] 6 |
D07460 |
D00633 |
Dopamine |
[3] 6, 7, 74 |
D07870 |
D00059 |
Levodopa |
[7] 2, 4, 6, 17, 90, 164, 201 |
D00502 |
Pergolide |
[1] 6 |
D08339 |
[1] DRD2 |
D01164 |
Aripiprazole |
[2] 6, 206 |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00702 |
Buspirone |
[2] 6, 51 |
D07593 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
D01745 |
Domperidone |
[5] 6, 13, 17, 51, 230 |
D07868 |
D01462 |
Lisuride |
[2] 6, 86 |
D08132 |
D07309 |
Melperone |
[1] 6 |
D09397 |
Pardoprunox |
[1] 6 |
D07305 |
Piribedil |
[1] 6 |
D00559 |
Pramipexole |
[2] 2, 6 |
D05575 |
D09953 |
Pridopidine |
[2] 6, 8 |
D00458 |
Quetiapine |
[2] 6, 13 |
D08456 |
D00784 |
Ropinirole |
[3] 6, 74, 309 |
D08489 |
D05768 |
Rotigotine |
[1] 6 |
[1] GRIA2 |
D08964 |
Perampanel |
[3] 2, 6, 144 |
D02696 |
Talampanel |
[2] 2, 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D02780 |
Acamprosate |
[2] 6, 206 |
D07058 |
D00777 |
Amantadine |
[4] 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
[1] MAOA |
D02561 |
Moclobemide |
[1] 6 |
[2] MAOA, MAOB |
D02579 |
Iproniazid |
[1] 6 |
D00505 |
Phenelzine |
[1] 6 |
D08349 |
[1] MAOB |
D02562 |
Rasagiline |
[4] 2, 5, 6, 17 |
D08469 |
D10829 |
D10158 |
Safinamide |
[2] 6, 17 |
D00785 |
Selegiline |
[1] 6 |
D03731 |
[1] SLC6A3 |
D03215 |
Armodafinil |
[3] 6, 13, 84 |
D01296 |
Methylphenidate |
[7] 6, 13, 34, 84, 113, 179, 206 |
D04999 |
41 | Collecting duct acid secretion 3 genes, 3 drugs (DrugBank), 20 diseases shown |
[2] ATP4A, ATP4B |
D01984 |
Esomeprazole |
[6] 6, 46, 86, 98, 298, 299 |
D04056 |
D07917 |
D09339 |
D00455 |
Omeprazole |
[15] 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
[1] CA2 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
42 | Complement and coagulation cascades 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] F8 |
D00291 |
Desmopressin |
[6] 6, 64, 72, 75, 225, 288 |
D02235 |
43 | Cortisol synthesis and secretion 7 genes, 3 drugs (DrugBank), 5 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[3] CACNA1G, CACNA1H, CACNA1I |
D00538 |
Zonisamide |
[1] 6 |
44 | Cushing syndrome 7 genes, 3 drugs (DrugBank), 5 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[3] CACNA1G, CACNA1H, CACNA1I |
D00538 |
Zonisamide |
[1] 6 |
45 | Cytokine-cytokine receptor interaction 4 genes, 5 drugs (DrugBank), 35 diseases shown |
[1] CSF2RA |
D05803 |
Sargramostim |
[6] 6, 28, 60, 62, 96, 229 |
[1] CSF3R |
D03235 |
Filgrastim |
[28] 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
[1] EPOR |
D03231 |
Erythropoietin |
[9] 2, 6, 13, 22, 46, 47, 70, 95, 96 |
[1] PRL |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
46 | Dilated cardiomyopathy (DCM) 9 genes, 8 drugs (DrugBank), 25 diseases shown |
[1] ADRB1 |
D00255 |
Carvedilol |
[4] 6, 57, 86, 113 |
D03415 |
D02349 |
Dipivefrin |
[1] 6 |
D01277 |
Droxidopa |
[3] 5, 6, 17 |
D00095 |
Epinephrine |
[9] 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
D00483 |
Propranolol |
[5] 6, 158, 167, 227, 278 |
D08443 |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 |
D00332 |
Gabapentin |
[7] 6, 13, 19, 70, 97, 226, 298 |
47 | Dopaminergic synapse 19 genes, 46 drugs (DrugBank), 40 diseases shown |
[2] CACNA1C, CACNA1D |
D00349 |
Isradipine |
[1] 6 |
[7] CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4, SCN1A |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[1] COMT |
D00781 |
Entacapone |
[2] 6, 17 |
D10825 |
Opicapone |
[1] 6 |
D00786 |
Tolcapone |
[3] 6, 28, 127 |
[1] DDC |
D03082 |
Benserazide |
[1] 6 |
D00558 |
Carbidopa |
[8] 2, 4, 6, 13, 17, 90, 164, 201 |
[2] DRD1, DRD2 |
D02004 |
Apomorphine |
[1] 6 |
D07460 |
D00502 |
Pergolide |
[1] 6 |
D08339 |
[5] DRD1, DRD2, DRD3, DRD4, DRD5 |
D00633 |
Dopamine |
[3] 6, 7, 74 |
D07870 |
D00059 |
Levodopa |
[7] 2, 4, 6, 17, 90, 164, 201 |
[2] DRD1, DRD5 |
D11431 |
Tavapadon |
[1] 6 |
[1] DRD2 |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00702 |
Buspirone |
[2] 6, 51 |
D07593 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
D01745 |
Domperidone |
[5] 6, 13, 17, 51, 230 |
D07868 |
D07309 |
Melperone |
[1] 6 |
D09953 |
Pridopidine |
[2] 6, 8 |
D00458 |
Quetiapine |
[2] 6, 13 |
D08456 |
D05768 |
Rotigotine |
[1] 6 |
[2] DRD2, DRD3 |
D01164 |
Aripiprazole |
[2] 6, 206 |
D09397 |
Pardoprunox |
[1] 6 |
D07305 |
Piribedil |
[1] 6 |
[3] DRD2, DRD3, DRD4 |
D01462 |
Lisuride |
[2] 6, 86 |
D08132 |
D00559 |
Pramipexole |
[2] 2, 6 |
D05575 |
D00784 |
Ropinirole |
[3] 6, 74, 309 |
D08489 |
[1] DRD4 |
D00283 |
Clozapine |
[1] 6 |
[4] GRIA1, GRIA2, GRIA3, GRIA4 |
D08964 |
Perampanel |
[3] 2, 6, 144 |
D02696 |
Talampanel |
[2] 2, 6 |
[2] GRIN2A, GRIN2B |
D02780 |
Acamprosate |
[2] 6, 206 |
D07058 |
D00777 |
Amantadine |
[4] 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
[1] MAOA |
D02561 |
Moclobemide |
[1] 6 |
[2] MAOA, MAOB |
D02579 |
Iproniazid |
[1] 6 |
D00505 |
Phenelzine |
[1] 6 |
D08349 |
[1] MAOB |
D02562 |
Rasagiline |
[4] 2, 5, 6, 17 |
D08469 |
D10829 |
D10158 |
Safinamide |
[2] 6, 17 |
D00785 |
Selegiline |
[1] 6 |
D03731 |
[1] SCN1A |
D00638 |
Flecainide |
[1] 6 |
D07962 |
D00358 |
Lidocaine |
[10] 6, 13, 46, 84, 86, 97, 168, 226, 231, 256 |
D02086 |
D08127 |
D01768 |
Oxybuprocaine |
[1] 6 |
D08319 |
D00538 |
Zonisamide |
[1] 6 |
[1] SLC6A3 |
D03215 |
Armodafinil |
[3] 6, 13, 84 |
D01296 |
Methylphenidate |
[7] 6, 13, 34, 84, 113, 179, 206 |
D04999 |
48 | Drug metabolism - cytochrome P450 2 genes, 6 drugs (DrugBank), 4 diseases shown |
[1] MAOA |
D02561 |
Moclobemide |
[1] 6 |
[2] MAOA, MAOB |
D02579 |
Iproniazid |
[1] 6 |
D00505 |
Phenelzine |
[1] 6 |
D08349 |
[1] MAOB |
D02562 |
Rasagiline |
[4] 2, 5, 6, 17 |
D08469 |
D10829 |
D10158 |
Safinamide |
[2] 6, 17 |
D00785 |
Selegiline |
[1] 6 |
D03731 |
49 | Drug metabolism - other enzymes 1 gene, 2 drugs (DrugBank), 8 diseases shown |
[1] XDH |
D00224 |
Allopurinol |
[6] 6, 46, 57, 66, 96, 97 |
D01206 |
Febuxostat |
[3] 2, 6, 13 |
50 | ECM-receptor interaction 1 gene, 1 drug (DrugBank), 4 diseases shown |
[1] SV2A |
D00709 |
Levetiracetam |
[4] 2, 4, 6, 13 |
51 | EGFR tyrosine kinase inhibitor resistance 3 genes, 2 drugs (DrugBank), 6 diseases shown |
[2] PDGFRA, PDGFRB |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
52 | Endocrine and other factor-regulated calcium reabsorption 1 gene, 2 drugs (DrugBank), 15 diseases shown |
[1] VDR |
D00188 |
Cholecalciferol |
[15] 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 |
D00299 |
Dihydrotachysterol |
[1] 6 |
53 | Endocrine resistance 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
54 | Endocytosis 2 genes, 2 drugs (DrugBank), 6 diseases shown |
[1] PDGFRA |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
55 | Epithelial cell signaling in Helicobacter pylori infection 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
56 | ErbB signaling pathway 2 genes, 2 drugs (DrugBank), 6 diseases shown |
[1] ABL1 |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
[2] ABL1, SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
57 | Estrogen signaling pathway 2 genes, 6 drugs (DrugBank), 17 diseases shown |
[1] OPRM1 |
D05111 |
Nalmefene |
[1] 6 |
D01340 |
Naloxone |
[2] 6, 226 |
D08249 |
D02095 |
Naltrexone |
[11] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 |
D05113 |
D03783 |
Oxycodone |
[7] 6, 13, 46, 70, 226, 231, 298 |
D05312 |
D05462 |
D01177 |
Remifentanil |
[2] 6, 70 |
D08473 |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
58 | Fluid shear stress and atherosclerosis 4 genes, 3 drugs (DrugBank), 24 diseases shown |
[1] NQO1 |
D00564 |
Warfarin |
[10] 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 |
D01280 |
D08682 |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
59 | Focal adhesion 3 genes, 2 drugs (DrugBank), 6 diseases shown |
[2] PDGFRA, PDGFRB |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
60 | FoxO signaling pathway 2 genes, 1 drug (DrugBank), 17 diseases shown |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
61 | GABAergic synapse 22 genes, 11 drugs (DrugBank), 27 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
[20] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00280 |
Clonazepam |
[1] 6 |
D02624 |
Eszopiclone |
[3] 6, 13, 46 |
D00697 |
Flumazenil |
[5] 6, 13, 17, 18, 206 |
D00550 |
Midazolam |
[10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
D00549 |
Propofol |
[8] 6, 21, 22, 34, 46, 84, 98, 296 |
D00706 |
Zolpidem |
[2] 5, 6 |
D08690 |
D01372 |
Zopiclone |
[1] 6 |
[1] SLC6A1 |
D00332 |
Gabapentin |
[7] 6, 13, 19, 70, 97, 226, 298 |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
62 | Gap junction 8 genes, 29 drugs (DrugBank), 32 diseases shown |
[1] ADRB1 |
D00255 |
Carvedilol |
[4] 6, 57, 86, 113 |
D03415 |
D02349 |
Dipivefrin |
[1] 6 |
D01277 |
Droxidopa |
[3] 5, 6, 17 |
D00095 |
Epinephrine |
[9] 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
D00483 |
Propranolol |
[5] 6, 158, 167, 227, 278 |
D08443 |
[1] DRD1 |
D11431 |
Tavapadon |
[1] 6 |
[2] DRD1, DRD2 |
D02004 |
Apomorphine |
[1] 6 |
D07460 |
D00633 |
Dopamine |
[3] 6, 7, 74 |
D07870 |
D00059 |
Levodopa |
[7] 2, 4, 6, 17, 90, 164, 201 |
D00502 |
Pergolide |
[1] 6 |
D08339 |
[1] DRD2 |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00702 |
Buspirone |
[2] 6, 51 |
D07593 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
D01745 |
Domperidone |
[5] 6, 13, 17, 51, 230 |
D07868 |
D01462 |
Lisuride |
[2] 6, 86 |
D08132 |
D07309 |
Melperone |
[1] 6 |
D09397 |
Pardoprunox |
[1] 6 |
D07305 |
Piribedil |
[1] 6 |
D00559 |
Pramipexole |
[2] 2, 6 |
D05575 |
D09953 |
Pridopidine |
[2] 6, 8 |
D00784 |
Ropinirole |
[3] 6, 74, 309 |
D08489 |
D05768 |
Rotigotine |
[1] 6 |
[2] DRD2, HTR2A |
D01164 |
Aripiprazole |
[2] 6, 206 |
D00458 |
Quetiapine |
[2] 6, 13 |
D08456 |
[1] HTR2A |
D09645 |
Nelotanserin |
[1] 6 |
[2] HTR2A, HTR2C |
D00283 |
Clozapine |
[1] 6 |
[1] HTR2C |
D02578 |
Agomelatine |
[1] 6 |
[2] PDGFRA, PDGFRB |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
63 | Gastric acid secretion 5 genes, 13 drugs (DrugBank), 23 diseases shown |
[2] ATP4A, ATP4B |
D01984 |
Esomeprazole |
[6] 6, 46, 86, 98, 298, 299 |
D04056 |
D07917 |
D09339 |
D00455 |
Omeprazole |
[15] 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
[1] CA2 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[1] CHRM3 |
D01699 |
Darifenacin |
[2] 6, 13 |
D03654 |
D07226 |
Fesoterodine |
[1] 6 |
D00540 |
Glycopyrronium |
[1] 6 |
D10938 |
D02212 |
Ipratropium |
[2] 6, 86 |
D00465 |
Oxybutynin |
[1] 6 |
D00722 |
D00525 |
Pilocarpine |
[3] 6, 53, 299 |
D02200 |
D05478 |
D01269 |
Solifenacin |
[1] 6 |
D08522 |
D00787 |
Trihexyphenidyl |
[2] 5, 6 |
D08638 |
D00397 |
Tropicamide |
[2] 6, 19 |
[1] HRH2 |
D00318 |
Famotidine |
[3] 6, 46, 86 |
64 | Glioma 2 genes, 1 drug (DrugBank), 5 diseases shown |
[2] PDGFRA, PDGFRB |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
65 | Glucagon signaling pathway 3 genes, 2 drugs (DrugBank), 21 diseases shown |
[1] PDE3B |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
66 | Glutamatergic synapse 16 genes, 9 drugs (DrugBank), 19 diseases shown |
[2] CACNA1C, CACNA1D |
D00349 |
Isradipine |
[1] 6 |
[11] CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[4] GRIA1, GRIA2, GRIA3, GRIA4 |
D08964 |
Perampanel |
[3] 2, 6, 144 |
D02696 |
Talampanel |
[2] 2, 6 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D02780 |
Acamprosate |
[2] 6, 206 |
D07058 |
D00777 |
Amantadine |
[4] 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
67 | Glycerophospholipid metabolism 1 gene, 4 drugs (DrugBank), 12 diseases shown |
[1] ACHE |
D00670 |
Donepezil |
[9] 5, 6, 13, 46, 78, 124, 127, 156, 206 |
D07869 |
D02173 |
Galantamine |
[2] 6, 127 |
D04292 |
D00487 |
Pyridostigmine |
[4] 3, 6, 11, 256 |
D02558 |
Rivastigmine |
[3] 5, 6, 13 |
D03822 |
68 | Glycine, serine and threonine metabolism 2 genes, 6 drugs (DrugBank), 4 diseases shown |
[1] MAOA |
D02561 |
Moclobemide |
[1] 6 |
[2] MAOA, MAOB |
D02579 |
Iproniazid |
[1] 6 |
D00505 |
Phenelzine |
[1] 6 |
D08349 |
[1] MAOB |
D02562 |
Rasagiline |
[4] 2, 5, 6, 17 |
D08469 |
D10829 |
D10158 |
Safinamide |
[2] 6, 17 |
D00785 |
Selegiline |
[1] 6 |
D03731 |
69 | GnRH secretion 8 genes, 4 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[3] CACNA1G, CACNA1H, CACNA1I |
D00538 |
Zonisamide |
[1] 6 |
[1] KCNJ11 |
D00594 |
Repaglinide |
[2] 6, 299 |
70 | GnRH signaling pathway 5 genes, 3 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
71 | Growth hormone synthesis, secretion and action 4 genes, 2 drugs (DrugBank), 5 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
72 | Hematopoietic cell lineage 4 genes, 5 drugs (DrugBank), 36 diseases shown |
[1] CSF2RA |
D05803 |
Sargramostim |
[6] 6, 28, 60, 62, 96, 229 |
[1] CSF3R |
D03235 |
Filgrastim |
[28] 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
[1] EPOR |
D03231 |
Erythropoietin |
[9] 2, 6, 13, 22, 46, 47, 70, 95, 96 |
[1] KIT |
D10229 |
Masitinib |
[6] 2, 5, 6, 13, 46, 96 |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
73 | Hepatitis B 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
74 | Hepatocellular carcinoma 1 gene, 1 drug (DrugBank), 10 diseases shown |
[1] NQO1 |
D00564 |
Warfarin |
[10] 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 |
D01280 |
D08682 |
75 | Herpes simplex virus 1 infection 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
76 | Histidine metabolism 2 genes, 6 drugs (DrugBank), 4 diseases shown |
[1] MAOA |
D02561 |
Moclobemide |
[1] 6 |
[2] MAOA, MAOB |
D02579 |
Iproniazid |
[1] 6 |
D00505 |
Phenelzine |
[1] 6 |
D08349 |
[1] MAOB |
D02562 |
Rasagiline |
[4] 2, 5, 6, 17 |
D08469 |
D10829 |
D10158 |
Safinamide |
[2] 6, 17 |
D00785 |
Selegiline |
[1] 6 |
D03731 |
77 | Human cytomegalovirus infection 3 genes, 3 drugs (DrugBank), 15 diseases shown |
[1] PDGFRA |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
78 | Human papillomavirus infection 2 genes, 2 drugs (DrugBank), 14 diseases shown |
[1] PDGFRB |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
79 | Human T-cell leukemia virus 1 infection 1 gene, 1 drug (DrugBank), 11 diseases shown |
[1] FDPS |
D01968 |
Zoledronic acid |
[11] 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333 |
D06378 |
D06379 |
D08689 |
80 | Huntington disease 3 genes, 6 drugs (DrugBank), 26 diseases shown |
[2] GRIN1, GRIN2B |
D02780 |
Acamprosate |
[2] 6, 206 |
D07058 |
D00777 |
Amantadine |
[4] 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
81 | Hypertrophic cardiomyopathy (HCM) 10 genes, 4 drugs (DrugBank), 26 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 |
D00332 |
Gabapentin |
[7] 6, 13, 19, 70, 97, 226, 298 |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
82 | IL-17 signaling pathway 1 gene, 1 drug (DrugBank), 13 diseases shown |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
83 | Inflammatory mediator regulation of TRP channels 5 genes, 9 drugs (DrugBank), 10 diseases shown |
[1] HRH1 |
D00814 |
Doxepin |
[1] 6 |
D07875 |
D00364 |
Loratadine |
[3] 6, 13, 46 |
[1] HTR2A |
D01164 |
Aripiprazole |
[2] 6, 206 |
D09645 |
Nelotanserin |
[1] 6 |
D00458 |
Quetiapine |
[2] 6, 13 |
D08456 |
[2] HTR2A, HTR2C |
D00283 |
Clozapine |
[1] 6 |
[1] HTR2C |
D02578 |
Agomelatine |
[1] 6 |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
[1] TRPV1 |
D00250 |
Capsaicin |
[6] 2, 6, 19, 86, 113, 226 |
84 | Influenza A 1 gene, 1 drug (DrugBank), 11 diseases shown |
[1] FDPS |
D01968 |
Zoledronic acid |
[11] 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333 |
D06378 |
D06379 |
D08689 |
85 | Insulin resistance 2 genes, 1 drug (DrugBank), 17 diseases shown |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
86 | Insulin secretion 9 genes, 18 drugs (DrugBank), 23 diseases shown |
[2] ABCC8, KCNJ11 |
D00594 |
Repaglinide |
[2] 6, 299 |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[1] CHRM3 |
D01699 |
Darifenacin |
[2] 6, 13 |
D03654 |
D07226 |
Fesoterodine |
[1] 6 |
D00540 |
Glycopyrronium |
[1] 6 |
D10938 |
D02212 |
Ipratropium |
[2] 6, 86 |
D00465 |
Oxybutynin |
[1] 6 |
D00722 |
D00525 |
Pilocarpine |
[3] 6, 53, 299 |
D02200 |
D05478 |
D01269 |
Solifenacin |
[1] 6 |
D08522 |
D00787 |
Trihexyphenidyl |
[2] 5, 6 |
D08638 |
D00397 |
Tropicamide |
[2] 6, 19 |
[1] GLP1R |
D04121 |
Exenatide |
[3] 6, 193, 233 |
D06404 |
Liraglutide |
[3] 6, 75, 193 |
D09729 |
Lixisenatide |
[1] 6 |
D10025 |
Semaglutide |
[1] 6 |
[1] SNAP25 |
D02735 |
Botulinum Toxin Type B |
[3] 2, 6, 51 |
D00783 |
Botulinum toxin type A |
[13] 2, 5, 6, 7, 13, 15, 17, 36, 51, 70, 113, 149, 226 |
87 | Insulin signaling pathway 3 genes, 2 drugs (DrugBank), 21 diseases shown |
[1] PDE3B |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
88 | JAK-STAT signaling pathway 6 genes, 6 drugs (DrugBank), 37 diseases shown |
[1] CSF2RA |
D05803 |
Sargramostim |
[6] 6, 28, 60, 62, 96, 229 |
[1] CSF3R |
D03235 |
Filgrastim |
[28] 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
[1] EPOR |
D03231 |
Erythropoietin |
[9] 2, 6, 13, 22, 46, 47, 70, 95, 96 |
[2] PDGFRA, PDGFRB |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
[1] PRL |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
89 | Kaposi sarcoma-associated herpesvirus infection 2 genes, 2 drugs (DrugBank), 14 diseases shown |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
90 | Leishmaniasis 1 gene, 1 drug (DrugBank), 13 diseases shown |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
91 | Long-term depression 3 genes, 3 drugs (DrugBank), 6 diseases shown |
[3] GRIA1, GRIA2, GRIA3 |
D08964 |
Perampanel |
[3] 2, 6, 144 |
D02696 |
Talampanel |
[2] 2, 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
92 | Long-term potentiation 8 genes, 9 drugs (DrugBank), 19 diseases shown |
[1] CACNA1C |
D00349 |
Isradipine |
[1] 6 |
[3] CACNA1C, GRIA1, GRIA2 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[2] GRIA1, GRIA2 |
D08964 |
Perampanel |
[3] 2, 6, 144 |
D02696 |
Talampanel |
[2] 2, 6 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D02780 |
Acamprosate |
[2] 6, 206 |
D07058 |
D00777 |
Amantadine |
[4] 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
93 | Longevity regulating pathway 3 genes, 2 drugs (DrugBank), 25 diseases shown |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
94 | Longevity regulating pathway - multiple species 2 genes, 1 drug (DrugBank), 17 diseases shown |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
95 | MAPK signaling pathway 14 genes, 6 drugs (DrugBank), 19 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[3] CACNA1G, CACNA1H, CACNA1I |
D00538 |
Zonisamide |
[1] 6 |
[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 |
D00332 |
Gabapentin |
[7] 6, 13, 19, 70, 97, 226, 298 |
[1] KIT |
D10229 |
Masitinib |
[6] 2, 5, 6, 13, 46, 96 |
[3] KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
96 | Melanogenesis 1 gene, 2 drugs (DrugBank), 10 diseases shown |
[1] KIT |
D10229 |
Masitinib |
[6] 2, 5, 6, 13, 46, 96 |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
97 | Melanoma 2 genes, 1 drug (DrugBank), 5 diseases shown |
[2] PDGFRA, PDGFRB |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
98 | Metabolic pathways 24 genes, 25 drugs (DrugBank), 67 diseases shown |
[2] ATP4A, ATP4B |
D01984 |
Esomeprazole |
[6] 6, 46, 86, 98, 298, 299 |
D04056 |
D07917 |
D09339 |
D00455 |
Omeprazole |
[15] 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
[2] CA2, CA4 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[1] COMT |
D00781 |
Entacapone |
[2] 6, 17 |
D10825 |
Opicapone |
[1] 6 |
D00786 |
Tolcapone |
[3] 6, 28, 127 |
[1] DDC |
D03082 |
Benserazide |
[1] 6 |
D00558 |
Carbidopa |
[8] 2, 4, 6, 13, 17, 90, 164, 201 |
[1] FDPS |
D01968 |
Zoledronic acid |
[11] 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333 |
D06378 |
D06379 |
D08689 |
[1] HMGCR |
D00359 |
Lovastatin |
[10] 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 |
D01915 |
Rosuvastatin |
[8] 6, 46, 49, 51, 79, 96, 271, 299 |
D08492 |
D00434 |
Simvastatin |
[19] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
[1] MAOA |
D02561 |
Moclobemide |
[1] 6 |
[2] MAOA, MAOB |
D02579 |
Iproniazid |
[1] 6 |
D00505 |
Phenelzine |
[1] 6 |
D08349 |
[1] MAOB |
D02562 |
Rasagiline |
[4] 2, 5, 6, 17 |
D08469 |
D10829 |
D10158 |
Safinamide |
[2] 6, 17 |
D00785 |
Selegiline |
[1] 6 |
D03731 |
[2] NQO1, VKORC1 |
D00564 |
Warfarin |
[10] 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 |
D01280 |
D08682 |
[9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
[1] PDE5A |
D02229 |
Sildenafil |
[16] 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
D08514 |
D02008 |
Tadalafil |
[6] 6, 51, 75, 84, 86, 113 |
[2] PTGS1, PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
[1] XDH |
D00224 |
Allopurinol |
[6] 6, 46, 57, 66, 96, 97 |
D01206 |
Febuxostat |
[3] 2, 6, 13 |
99 | MicroRNAs in cancer 4 genes, 3 drugs (DrugBank), 15 diseases shown |
[1] ABL1 |
D09664 |
Saracatinib |
[2] 6, 89 |
[3] ABL1, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
100 | Mineral absorption 2 genes, 3 drugs (DrugBank), 16 diseases shown |
[1] CLCN2 |
D04790 |
Lubiprostone |
[4] 6, 13, 290, 299 |
[1] VDR |
D00188 |
Cholecalciferol |
[15] 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 |
D00299 |
Dihydrotachysterol |
[1] 6 |
101 | Mitophagy - animal 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
102 | Morphine addiction 27 genes, 19 drugs (DrugBank), 39 diseases shown |
[9] ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
[1] DRD1 |
D02004 |
Apomorphine |
[1] 6 |
D07460 |
D00633 |
Dopamine |
[3] 6, 7, 74 |
D07870 |
D00059 |
Levodopa |
[7] 2, 4, 6, 17, 90, 164, 201 |
D00502 |
Pergolide |
[1] 6 |
D08339 |
D11431 |
Tavapadon |
[1] 6 |
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00280 |
Clonazepam |
[1] 6 |
D02624 |
Eszopiclone |
[3] 6, 13, 46 |
D00697 |
Flumazenil |
[5] 6, 13, 17, 18, 206 |
D00550 |
Midazolam |
[10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
D00549 |
Propofol |
[8] 6, 21, 22, 34, 46, 84, 98, 296 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
D00706 |
Zolpidem |
[2] 5, 6 |
D08690 |
D01372 |
Zopiclone |
[1] 6 |
[1] OPRM1 |
D05111 |
Nalmefene |
[1] 6 |
D01340 |
Naloxone |
[2] 6, 226 |
D08249 |
D02095 |
Naltrexone |
[11] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 |
D05113 |
D03783 |
Oxycodone |
[7] 6, 13, 46, 70, 226, 231, 298 |
D05312 |
D05462 |
D01177 |
Remifentanil |
[2] 6, 70 |
D08473 |
103 | mTOR signaling pathway 2 genes, 1 drug (DrugBank), 17 diseases shown |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
104 | Neuroactive ligand-receptor interaction 89 genes, 90 drugs (DrugBank), 77 diseases shown |
[2] ADORA1, ADORA2A |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
[1] ADORA2A |
D04641 |
Istradefylline |
[1] 6 |
D09717 |
Preladenant |
[1] 6 |
D10174 |
Tozadenant |
[1] 6 |
[1] ADRA1A |
D01965 |
Silodosin |
[2] 6, 13 |
[3] ADRA1A, ADRA1B, ADRA1D |
D01307 |
Midodrine |
[3] 6, 17, 58 |
D08220 |
D00610 |
Terazosin |
[1] 6 |
D08569 |
[6] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C |
D02268 |
Ergoloid mesylate |
[1] 6 |
[9] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 |
D02349 |
Dipivefrin |
[1] 6 |
D01277 |
Droxidopa |
[3] 5, 6, 17 |
D00095 |
Epinephrine |
[9] 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 |
D00255 |
Carvedilol |
[4] 6, 57, 86, 113 |
D03415 |
[3] ADRA2A, ADRA2B, ADRA2C |
D00281 |
Clonidine |
[2] 6, 78 |
D00604 |
D00514 |
Dexmedetomidine |
[11] 2, 4, 6, 21, 34, 70, 113, 212, 215, 226, 280 |
D01205 |
[6] ADRA2A, ADRA2B, ADRA2C, DRD4, HTR2A, HTR2C |
D00283 |
Clozapine |
[1] 6 |
[3] ADRB1, ADRB2, ADRB3 |
D00483 |
Propranolol |
[5] 6, 158, 167, 227, 278 |
D08443 |
[1] ADRB3 |
D09535 |
Mirabegron |
[3] 6, 13, 226 |
[1] AVPR2 |
D00291 |
Desmopressin |
[6] 6, 64, 72, 75, 225, 288 |
D02235 |
[5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 |
D02212 |
Ipratropium |
[2] 6, 86 |
D00465 |
Oxybutynin |
[1] 6 |
D00722 |
D00787 |
Trihexyphenidyl |
[2] 5, 6 |
D08638 |
D00397 |
Tropicamide |
[2] 6, 19 |
[2] CHRM2, CHRM3 |
D07226 |
Fesoterodine |
[1] 6 |
D00525 |
Pilocarpine |
[3] 6, 53, 299 |
D02200 |
D05478 |
[1] CHRM3 |
D01699 |
Darifenacin |
[2] 6, 13 |
D03654 |
D00540 |
Glycopyrronium |
[1] 6 |
D10938 |
D01269 |
Solifenacin |
[1] 6 |
D08522 |
[16] CHRNA1, CHRNA10, CHRNA2, CHRNA3, CHRNA4, CHRNA5, CHRNA6, CHRNA7, CHRNA9, CHRNB1, CHRNB2, CHRNB3, CHRNB4, CHRND, CHRNE, CHRNG |
D03365 |
Nicotine |
[2] 6, 84 |
D05156 |
D05157 |
[2] CHRNA4, CHRNB2 |
D08669 |
Varenicline |
[2] 6, 18 |
[2] CNR1, CNR2 |
D10915 |
Cannabidiol |
[14] 2, 6, 13, 46, 95, 96, 97, 140, 144, 145, 157, 158, 193, 271 |
D05099 |
Nabilone |
[2] 6, 13 |
[2] DRD1, DRD2 |
D02004 |
Apomorphine |
[1] 6 |
D07460 |
D00502 |
Pergolide |
[1] 6 |
D08339 |
[5] DRD1, DRD2, DRD3, DRD4, DRD5 |
D00633 |
Dopamine |
[3] 6, 7, 74 |
D07870 |
D00059 |
Levodopa |
[7] 2, 4, 6, 17, 90, 164, 201 |
[2] DRD1, DRD5 |
D11431 |
Tavapadon |
[1] 6 |
[1] DRD2 |
D01745 |
Domperidone |
[5] 6, 13, 17, 51, 230 |
D07868 |
D07309 |
Melperone |
[1] 6 |
D09953 |
Pridopidine |
[2] 6, 8 |
D05768 |
Rotigotine |
[1] 6 |
[2] DRD2, DRD3 |
D07305 |
Piribedil |
[1] 6 |
[3] DRD2, DRD3, DRD4 |
D01462 |
Lisuride |
[2] 6, 86 |
D08132 |
D00559 |
Pramipexole |
[2] 2, 6 |
D05575 |
D00784 |
Ropinirole |
[3] 6, 74, 309 |
D08489 |
[3] DRD2, DRD3, HTR1A |
D09397 |
Pardoprunox |
[1] 6 |
[4] DRD2, DRD3, HTR1A, HTR2A |
D01164 |
Aripiprazole |
[2] 6, 206 |
[2] DRD2, HTR1A |
D00702 |
Buspirone |
[2] 6, 51 |
D07593 |
[2] DRD2, HTR2A |
D00458 |
Quetiapine |
[2] 6, 13 |
D08456 |
[2] DRD2, PRL |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00280 |
Clonazepam |
[1] 6 |
D02624 |
Eszopiclone |
[3] 6, 13, 46 |
D00697 |
Flumazenil |
[5] 6, 13, 17, 18, 206 |
D00550 |
Midazolam |
[10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
D00549 |
Propofol |
[8] 6, 21, 22, 34, 46, 84, 98, 296 |
D00706 |
Zolpidem |
[2] 5, 6 |
D08690 |
D01372 |
Zopiclone |
[1] 6 |
[25] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[1] GLP1R |
D04121 |
Exenatide |
[3] 6, 193, 233 |
D06404 |
Liraglutide |
[3] 6, 75, 193 |
D09729 |
Lixisenatide |
[1] 6 |
D10025 |
Semaglutide |
[1] 6 |
[4] GRIA1, GRIA2, GRIA3, GRIA4 |
D08964 |
Perampanel |
[3] 2, 6, 144 |
D02696 |
Talampanel |
[2] 2, 6 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D02780 |
Acamprosate |
[2] 6, 206 |
D07058 |
D00777 |
Amantadine |
[4] 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
[2] HCRTR1, HCRTR2 |
D10082 |
Suvorexant |
[3] 5, 6, 13 |
[1] HRH1 |
D00814 |
Doxepin |
[1] 6 |
D07875 |
D00364 |
Loratadine |
[3] 6, 13, 46 |
[1] HRH2 |
D00318 |
Famotidine |
[3] 6, 46, 86 |
[1] HRH3 |
D09870 |
Bavisant |
[1] 6 |
D10749 |
Pitolisant |
[1] 6 |
[2] HTR1B, HTR1D |
D00415 |
Zolmitriptan |
[1] 6 |
[1] HTR2A |
D09645 |
Nelotanserin |
[1] 6 |
[3] HTR2C, MTNR1A, MTNR1B |
D02578 |
Agomelatine |
[1] 6 |
[2] MTNR1A, MTNR1B |
D08170 |
Melatonin |
[8] 6, 13, 46, 49, 90, 97, 144, 202 |
D02689 |
Ramelteon |
[3] 6, 8, 46 |
[1] NR3C1 |
D00088 |
Hydrocortisone |
[8] 6, 53, 75, 78, 81, 83, 97, 299 |
D00165 |
Hydrocortisone acetate |
[8] 6, 53, 75, 78, 81, 83, 97, 299 |
D01442 |
Hydrocortisone succinate |
[3] 6, 81, 83 |
D00385 |
Triamcinolone |
[18] 6, 10, 13, 35, 40, 41, 42, 43, 44, 45, 46, 56, 70, 90, 96, 97, 226, 298 |
D00983 |
D00984 |
D00985 |
D06216 |
[3] OPRD1, OPRK1, OPRM1 |
D05111 |
Nalmefene |
[1] 6 |
D01340 |
Naloxone |
[2] 6, 226 |
D08249 |
D02095 |
Naltrexone |
[11] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 |
D05113 |
D03783 |
Oxycodone |
[7] 6, 13, 46, 70, 226, 231, 298 |
D05312 |
D05462 |
[1] OPRM1 |
D01177 |
Remifentanil |
[2] 6, 70 |
D08473 |
[1] TRPV1 |
D00250 |
Capsaicin |
[6] 2, 6, 19, 86, 113, 226 |
105 | Neurotrophin signaling pathway 1 gene, 2 drugs (DrugBank), 6 diseases shown |
[1] ABL1 |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
D09664 |
Saracatinib |
[2] 6, 89 |
106 | NF-kappa B signaling pathway 1 gene, 1 drug (DrugBank), 13 diseases shown |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
107 | Nicotine addiction 29 genes, 17 drugs (DrugBank), 31 diseases shown |
[4] CHRNA4, CHRNA6, CHRNA7, CHRNB2 |
D03365 |
Nicotine |
[2] 6, 84 |
D05156 |
D05157 |
[2] CHRNA4, CHRNB2 |
D08669 |
Varenicline |
[2] 6, 18 |
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00280 |
Clonazepam |
[1] 6 |
D02624 |
Eszopiclone |
[3] 6, 13, 46 |
D00697 |
Flumazenil |
[5] 6, 13, 17, 18, 206 |
D00550 |
Midazolam |
[10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
D00549 |
Propofol |
[8] 6, 21, 22, 34, 46, 84, 98, 296 |
D00706 |
Zolpidem |
[2] 5, 6 |
D08690 |
D01372 |
Zopiclone |
[1] 6 |
[20] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[4] GRIA1, GRIA2, GRIA3, GRIA4 |
D08964 |
Perampanel |
[3] 2, 6, 144 |
D02696 |
Talampanel |
[2] 2, 6 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D02780 |
Acamprosate |
[2] 6, 206 |
D07058 |
D00777 |
Amantadine |
[4] 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
108 | Nitrogen metabolism 2 genes, 1 drug (DrugBank), 5 diseases shown |
[2] CA2, CA4 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
109 | Non-alcoholic fatty liver disease (NAFLD) 2 genes, 1 drug (DrugBank), 17 diseases shown |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
110 | Olfactory transduction 2 genes, 1 drug (DrugBank), 6 diseases shown |
[2] PDE1B, PDE2A |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
111 | Osteoclast differentiation 1 gene, 1 drug (DrugBank), 17 diseases shown |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
112 | Ovarian steroidogenesis 1 gene, 1 drug (DrugBank), 13 diseases shown |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
113 | Oxidative phosphorylation 2 genes, 2 drugs (DrugBank), 16 diseases shown |
[2] ATP4A, ATP4B |
D01984 |
Esomeprazole |
[6] 6, 46, 86, 98, 298, 299 |
D04056 |
D07917 |
D09339 |
D00455 |
Omeprazole |
[15] 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
114 | Oxytocin signaling pathway 12 genes, 6 drugs (DrugBank), 34 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 |
D00332 |
Gabapentin |
[7] 6, 13, 19, 70, 97, 226, 298 |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
115 | Pancreatic secretion 3 genes, 11 drugs (DrugBank), 12 diseases shown |
[1] CA2 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[1] CHRM3 |
D01699 |
Darifenacin |
[2] 6, 13 |
D03654 |
D07226 |
Fesoterodine |
[1] 6 |
D00540 |
Glycopyrronium |
[1] 6 |
D10938 |
D02212 |
Ipratropium |
[2] 6, 86 |
D00465 |
Oxybutynin |
[1] 6 |
D00722 |
D00525 |
Pilocarpine |
[3] 6, 53, 299 |
D02200 |
D05478 |
D01269 |
Solifenacin |
[1] 6 |
D08522 |
D00787 |
Trihexyphenidyl |
[2] 5, 6 |
D08638 |
D00397 |
Tropicamide |
[2] 6, 19 |
[1] SLC12A2 |
D00247 |
Bumetanide |
[2] 6, 158 |
116 | Parathyroid hormone synthesis, secretion and action 5 genes, 3 drugs (DrugBank), 17 diseases shown |
[4] PDE4A, PDE4B, PDE4C, PDE4D |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
[1] VDR |
D00188 |
Cholecalciferol |
[15] 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 |
D00299 |
Dihydrotachysterol |
[1] 6 |
117 | Parkinson disease 4 genes, 25 drugs (DrugBank), 25 diseases shown |
[1] ADORA2A |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
D04641 |
Istradefylline |
[1] 6 |
D09717 |
Preladenant |
[1] 6 |
D10174 |
Tozadenant |
[1] 6 |
[1] DRD1 |
D11431 |
Tavapadon |
[1] 6 |
[2] DRD1, DRD2 |
D02004 |
Apomorphine |
[1] 6 |
D07460 |
D00633 |
Dopamine |
[3] 6, 7, 74 |
D07870 |
D00059 |
Levodopa |
[7] 2, 4, 6, 17, 90, 164, 201 |
D00502 |
Pergolide |
[1] 6 |
D08339 |
[1] DRD2 |
D01164 |
Aripiprazole |
[2] 6, 206 |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00702 |
Buspirone |
[2] 6, 51 |
D07593 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
D01745 |
Domperidone |
[5] 6, 13, 17, 51, 230 |
D07868 |
D01462 |
Lisuride |
[2] 6, 86 |
D08132 |
D07309 |
Melperone |
[1] 6 |
D09397 |
Pardoprunox |
[1] 6 |
D07305 |
Piribedil |
[1] 6 |
D00559 |
Pramipexole |
[2] 2, 6 |
D05575 |
D09953 |
Pridopidine |
[2] 6, 8 |
D00458 |
Quetiapine |
[2] 6, 13 |
D08456 |
D00784 |
Ropinirole |
[3] 6, 74, 309 |
D08489 |
D05768 |
Rotigotine |
[1] 6 |
[1] SLC6A3 |
D03215 |
Armodafinil |
[3] 6, 13, 84 |
D01296 |
Methylphenidate |
[7] 6, 13, 34, 84, 113, 179, 206 |
D04999 |
118 | Pathogenic Escherichia coli infection 1 gene, 2 drugs (DrugBank), 6 diseases shown |
[1] ABL1 |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
D09664 |
Saracatinib |
[2] 6, 89 |
119 | Pathways in cancer 10 genes, 9 drugs (DrugBank), 52 diseases shown |
[1] ABL1 |
D09664 |
Saracatinib |
[2] 6, 89 |
[4] ABL1, KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
[1] CSF2RA |
D05803 |
Sargramostim |
[6] 6, 28, 60, 62, 96, 229 |
[1] CSF3R |
D03235 |
Filgrastim |
[28] 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
[1] EPOR |
D03231 |
Erythropoietin |
[9] 2, 6, 13, 22, 46, 47, 70, 95, 96 |
[1] KIT |
D10229 |
Masitinib |
[6] 2, 5, 6, 13, 46, 96 |
[1] NQO1 |
D00564 |
Warfarin |
[10] 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 |
D01280 |
D08682 |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
120 | Peroxisome 1 gene, 2 drugs (DrugBank), 8 diseases shown |
[1] XDH |
D00224 |
Allopurinol |
[6] 6, 46, 57, 66, 96, 97 |
D01206 |
Febuxostat |
[3] 2, 6, 13 |
121 | Phenylalanine metabolism 3 genes, 8 drugs (DrugBank), 9 diseases shown |
[1] DDC |
D03082 |
Benserazide |
[1] 6 |
D00558 |
Carbidopa |
[8] 2, 4, 6, 13, 17, 90, 164, 201 |
[1] MAOA |
D02561 |
Moclobemide |
[1] 6 |
[2] MAOA, MAOB |
D02579 |
Iproniazid |
[1] 6 |
D00505 |
Phenelzine |
[1] 6 |
D08349 |
[1] MAOB |
D02562 |
Rasagiline |
[4] 2, 5, 6, 17 |
D08469 |
D10829 |
D10158 |
Safinamide |
[2] 6, 17 |
D00785 |
Selegiline |
[1] 6 |
D03731 |
122 | Phospholipase D signaling pathway 4 genes, 3 drugs (DrugBank), 15 diseases shown |
[1] AVPR2 |
D00291 |
Desmopressin |
[6] 6, 64, 72, 75, 225, 288 |
D02235 |
[1] KIT |
D10229 |
Masitinib |
[6] 2, 5, 6, 13, 46, 96 |
[3] KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
123 | PI3K-Akt signaling pathway 10 genes, 13 drugs (DrugBank), 48 diseases shown |
[2] CHRM1, CHRM2 |
D02212 |
Ipratropium |
[2] 6, 86 |
D00465 |
Oxybutynin |
[1] 6 |
D00722 |
D00787 |
Trihexyphenidyl |
[2] 5, 6 |
D08638 |
D00397 |
Tropicamide |
[2] 6, 19 |
[1] CHRM2 |
D07226 |
Fesoterodine |
[1] 6 |
D00525 |
Pilocarpine |
[3] 6, 53, 299 |
D02200 |
D05478 |
[1] CSF3R |
D03235 |
Filgrastim |
[28] 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
[1] EPOR |
D03231 |
Erythropoietin |
[9] 2, 6, 13, 22, 46, 47, 70, 95, 96 |
[1] KIT |
D10229 |
Masitinib |
[6] 2, 5, 6, 13, 46, 96 |
[3] KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
[1] PRL |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
124 | Platelet activation 2 genes, 2 drugs (DrugBank), 14 diseases shown |
[1] PTGS1 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
125 | PPAR signaling pathway 1 gene, 1 drug (DrugBank), 17 diseases shown |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
126 | Progesterone-mediated oocyte maturation 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] PDE3B |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
127 | Prolactin signaling pathway 2 genes, 3 drugs (DrugBank), 4 diseases shown |
[1] PRL |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
128 | Prostate cancer 3 genes, 2 drugs (DrugBank), 5 diseases shown |
[2] PDGFRA, PDGFRB |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
[1] SRD5A2 |
D00321 |
Finasteride |
[1] 6 |
129 | Proteoglycans in cancer 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
130 | Proximal tubule bicarbonate reclamation 2 genes, 1 drug (DrugBank), 5 diseases shown |
[2] CA2, CA4 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
131 | Purine metabolism 10 genes, 5 drugs (DrugBank), 24 diseases shown |
[9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
[1] PDE5A |
D02229 |
Sildenafil |
[16] 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
D08514 |
D02008 |
Tadalafil |
[6] 6, 51, 75, 84, 86, 113 |
[1] XDH |
D00224 |
Allopurinol |
[6] 6, 46, 57, 66, 96, 97 |
D01206 |
Febuxostat |
[3] 2, 6, 13 |
132 | Rap1 signaling pathway 10 genes, 32 drugs (DrugBank), 39 diseases shown |
[1] ADORA2A |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
D04641 |
Istradefylline |
[1] 6 |
D09717 |
Preladenant |
[1] 6 |
D10174 |
Tozadenant |
[1] 6 |
[1] CNR1 |
D10915 |
Cannabidiol |
[14] 2, 6, 13, 46, 95, 96, 97, 140, 144, 145, 157, 158, 193, 271 |
D05099 |
Nabilone |
[2] 6, 13 |
[1] DRD2 |
D02004 |
Apomorphine |
[1] 6 |
D07460 |
D01164 |
Aripiprazole |
[2] 6, 206 |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00702 |
Buspirone |
[2] 6, 51 |
D07593 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
D01745 |
Domperidone |
[5] 6, 13, 17, 51, 230 |
D07868 |
D00633 |
Dopamine |
[3] 6, 7, 74 |
D07870 |
D00059 |
Levodopa |
[7] 2, 4, 6, 17, 90, 164, 201 |
D01462 |
Lisuride |
[2] 6, 86 |
D08132 |
D07309 |
Melperone |
[1] 6 |
D09397 |
Pardoprunox |
[1] 6 |
D00502 |
Pergolide |
[1] 6 |
D08339 |
D07305 |
Piribedil |
[1] 6 |
D00559 |
Pramipexole |
[2] 2, 6 |
D05575 |
D09953 |
Pridopidine |
[2] 6, 8 |
D00458 |
Quetiapine |
[2] 6, 13 |
D08456 |
D00784 |
Ropinirole |
[3] 6, 74, 309 |
D08489 |
D05768 |
Rotigotine |
[1] 6 |
[3] GRIN1, GRIN2A, GRIN2B |
D02780 |
Acamprosate |
[2] 6, 206 |
D07058 |
D00777 |
Amantadine |
[4] 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
[1] KIT |
D10229 |
Masitinib |
[6] 2, 5, 6, 13, 46, 96 |
[3] KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
133 | Ras signaling pathway 7 genes, 8 drugs (DrugBank), 21 diseases shown |
[1] ABL1 |
D09664 |
Saracatinib |
[2] 6, 89 |
[4] ABL1, KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
[3] GRIN1, GRIN2A, GRIN2B |
D02780 |
Acamprosate |
[2] 6, 206 |
D07058 |
D00777 |
Amantadine |
[4] 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
[1] KIT |
D10229 |
Masitinib |
[6] 2, 5, 6, 13, 46, 96 |
134 | Regulation of actin cytoskeleton 8 genes, 11 drugs (DrugBank), 11 diseases shown |
[5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 |
D02212 |
Ipratropium |
[2] 6, 86 |
D00465 |
Oxybutynin |
[1] 6 |
D00722 |
D00787 |
Trihexyphenidyl |
[2] 5, 6 |
D08638 |
D00397 |
Tropicamide |
[2] 6, 19 |
[2] CHRM2, CHRM3 |
D07226 |
Fesoterodine |
[1] 6 |
D00525 |
Pilocarpine |
[3] 6, 53, 299 |
D02200 |
D05478 |
[1] CHRM3 |
D01699 |
Darifenacin |
[2] 6, 13 |
D03654 |
D00540 |
Glycopyrronium |
[1] 6 |
D10938 |
D01269 |
Solifenacin |
[1] 6 |
D08522 |
[2] PDGFRA, PDGFRB |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
135 | Regulation of lipolysis in adipocytes 7 genes, 8 drugs (DrugBank), 27 diseases shown |
[2] ADORA1, PDE3B |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
[2] ADRB1, ADRB2 |
D00255 |
Carvedilol |
[4] 6, 57, 86, 113 |
D03415 |
[3] ADRB1, ADRB2, ADRB3 |
D02349 |
Dipivefrin |
[1] 6 |
D01277 |
Droxidopa |
[3] 5, 6, 17 |
D00095 |
Epinephrine |
[9] 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
D00483 |
Propranolol |
[5] 6, 158, 167, 227, 278 |
D08443 |
[1] ADRB3 |
D09535 |
Mirabegron |
[3] 6, 13, 226 |
[2] PTGS1, PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
136 | Relaxin signaling pathway 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
137 | Renin secretion 11 genes, 9 drugs (DrugBank), 24 diseases shown |
[4] ADORA1, PDE1B, PDE3A, PDE3B |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
[2] ADRB1, ADRB2 |
D00255 |
Carvedilol |
[4] 6, 57, 86, 113 |
D03415 |
[3] ADRB1, ADRB2, ADRB3 |
D02349 |
Dipivefrin |
[1] 6 |
D01277 |
Droxidopa |
[3] 5, 6, 17 |
D00095 |
Epinephrine |
[9] 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
D00483 |
Propranolol |
[5] 6, 158, 167, 227, 278 |
D08443 |
[1] ADRB3 |
D09535 |
Mirabegron |
[3] 6, 13, 226 |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
138 | Retrograde endocannabinoid signaling 26 genes, 14 drugs (DrugBank), 34 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
[24] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[1] CNR1 |
D10915 |
Cannabidiol |
[14] 2, 6, 13, 46, 95, 96, 97, 140, 144, 145, 157, 158, 193, 271 |
D05099 |
Nabilone |
[2] 6, 13 |
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00280 |
Clonazepam |
[1] 6 |
D02624 |
Eszopiclone |
[3] 6, 13, 46 |
D00697 |
Flumazenil |
[5] 6, 13, 17, 18, 206 |
D00550 |
Midazolam |
[10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
D00549 |
Propofol |
[8] 6, 21, 22, 34, 46, 84, 98, 296 |
D00706 |
Zolpidem |
[2] 5, 6 |
D08690 |
D01372 |
Zopiclone |
[1] 6 |
[4] GRIA1, GRIA2, GRIA3, GRIA4 |
D08964 |
Perampanel |
[3] 2, 6, 144 |
D02696 |
Talampanel |
[2] 2, 6 |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
139 | Salivary secretion 8 genes, 20 drugs (DrugBank), 21 diseases shown |
[1] ADRA1A |
D01965 |
Silodosin |
[2] 6, 13 |
[3] ADRA1A, ADRA1B, ADRA1D |
D02268 |
Ergoloid mesylate |
[1] 6 |
D01307 |
Midodrine |
[3] 6, 17, 58 |
D08220 |
D00610 |
Terazosin |
[1] 6 |
D08569 |
[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 |
D00255 |
Carvedilol |
[4] 6, 57, 86, 113 |
D03415 |
[6] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 |
D02349 |
Dipivefrin |
[1] 6 |
D01277 |
Droxidopa |
[3] 5, 6, 17 |
D00095 |
Epinephrine |
[9] 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
[3] ADRB1, ADRB2, ADRB3 |
D00483 |
Propranolol |
[5] 6, 158, 167, 227, 278 |
D08443 |
[1] ADRB3 |
D09535 |
Mirabegron |
[3] 6, 13, 226 |
[1] CHRM3 |
D01699 |
Darifenacin |
[2] 6, 13 |
D03654 |
D07226 |
Fesoterodine |
[1] 6 |
D00540 |
Glycopyrronium |
[1] 6 |
D10938 |
D02212 |
Ipratropium |
[2] 6, 86 |
D00465 |
Oxybutynin |
[1] 6 |
D00722 |
D00525 |
Pilocarpine |
[3] 6, 53, 299 |
D02200 |
D05478 |
D01269 |
Solifenacin |
[1] 6 |
D08522 |
D00787 |
Trihexyphenidyl |
[2] 5, 6 |
D08638 |
D00397 |
Tropicamide |
[2] 6, 19 |
[1] SLC12A2 |
D00247 |
Bumetanide |
[2] 6, 158 |
140 | Serotonergic synapse 23 genes, 33 drugs (DrugBank), 36 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
[7] CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRB1, GABRB2, GABRB3 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[1] DDC |
D03082 |
Benserazide |
[1] 6 |
D00558 |
Carbidopa |
[8] 2, 4, 6, 13, 17, 90, 164, 201 |
[3] GABRB1, GABRB2, GABRB3 |
D00280 |
Clonazepam |
[1] 6 |
D02624 |
Eszopiclone |
[3] 6, 13, 46 |
D00697 |
Flumazenil |
[5] 6, 13, 17, 18, 206 |
D00550 |
Midazolam |
[10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
D00549 |
Propofol |
[8] 6, 21, 22, 34, 46, 84, 98, 296 |
D00706 |
Zolpidem |
[2] 5, 6 |
D08690 |
D01372 |
Zopiclone |
[1] 6 |
[1] HTR1A |
D00702 |
Buspirone |
[2] 6, 51 |
D07593 |
D09397 |
Pardoprunox |
[1] 6 |
[2] HTR1A, HTR2A |
D01164 |
Aripiprazole |
[2] 6, 206 |
[2] HTR1B, HTR1D |
D00415 |
Zolmitriptan |
[1] 6 |
[1] HTR2A |
D09645 |
Nelotanserin |
[1] 6 |
D00458 |
Quetiapine |
[2] 6, 13 |
D08456 |
[7] HTR2A, HTR2C, HTR3A, HTR3B, HTR3C, HTR3D, HTR3E |
D00283 |
Clozapine |
[1] 6 |
[1] HTR2C |
D02578 |
Agomelatine |
[1] 6 |
[1] MAOA |
D02561 |
Moclobemide |
[1] 6 |
[2] MAOA, MAOB |
D02579 |
Iproniazid |
[1] 6 |
D00505 |
Phenelzine |
[1] 6 |
D08349 |
[1] MAOB |
D02562 |
Rasagiline |
[4] 2, 5, 6, 17 |
D08469 |
D10829 |
D10158 |
Safinamide |
[2] 6, 17 |
D00785 |
Selegiline |
[1] 6 |
D03731 |
[2] PTGS1, PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
[1] SLC6A4 |
D00814 |
Doxepin |
[1] 6 |
D07875 |
D01179 |
Duloxetine |
[3] 6, 13, 49 |
D07880 |
D02567 |
Escitalopram |
[3] 2, 6, 13 |
D07704 |
D07913 |
D00816 |
Nortriptyline |
[2] 6, 226 |
D08288 |
D02260 |
Paroxetine |
[3] 6, 13, 46 |
D02362 |
D05374 |
D05375 |
D00825 |
Sertraline |
[3] 6, 8, 206 |
D02360 |
D00821 |
Venlafaxine |
[3] 6, 13, 46 |
D08670 |
141 | Shigellosis 2 genes, 2 drugs (DrugBank), 6 diseases shown |
[1] ABL1 |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
[2] ABL1, SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
142 | Small cell lung cancer 1 gene, 1 drug (DrugBank), 13 diseases shown |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
143 | Sphingolipid signaling pathway 2 genes, 5 drugs (DrugBank), 18 diseases shown |
[1] ADORA1 |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
[1] OPRD1 |
D05111 |
Nalmefene |
[1] 6 |
D01340 |
Naloxone |
[2] 6, 226 |
D08249 |
D02095 |
Naltrexone |
[11] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 |
D05113 |
D03783 |
Oxycodone |
[7] 6, 13, 46, 70, 226, 231, 298 |
D05312 |
D05462 |
144 | Steroid hormone biosynthesis 2 genes, 4 drugs (DrugBank), 4 diseases shown |
[1] COMT |
D00781 |
Entacapone |
[2] 6, 17 |
D10825 |
Opicapone |
[1] 6 |
D00786 |
Tolcapone |
[3] 6, 28, 127 |
[1] SRD5A2 |
D00321 |
Finasteride |
[1] 6 |
145 | Synaptic vesicle cycle 5 genes, 13 drugs (DrugBank), 23 diseases shown |
[1] SLC6A1 |
D00332 |
Gabapentin |
[7] 6, 13, 19, 70, 97, 226, 298 |
[1] SLC6A2 |
D02574 |
Atomoxetine |
[3] 6, 8, 13 |
D07473 |
[2] SLC6A2, SLC6A3 |
D01296 |
Methylphenidate |
[7] 6, 13, 34, 84, 113, 179, 206 |
D04999 |
[2] SLC6A2, SLC6A4 |
D00814 |
Doxepin |
[1] 6 |
D07875 |
D01179 |
Duloxetine |
[3] 6, 13, 49 |
D07880 |
D00816 |
Nortriptyline |
[2] 6, 226 |
D08288 |
D00821 |
Venlafaxine |
[3] 6, 13, 46 |
D08670 |
[1] SLC6A3 |
D03215 |
Armodafinil |
[3] 6, 13, 84 |
[1] SLC6A4 |
D02567 |
Escitalopram |
[3] 2, 6, 13 |
D07704 |
D07913 |
D02260 |
Paroxetine |
[3] 6, 13, 46 |
D02362 |
D05374 |
D05375 |
D00825 |
Sertraline |
[3] 6, 8, 206 |
D02360 |
[1] SNAP25 |
D02735 |
Botulinum Toxin Type B |
[3] 2, 6, 51 |
D00783 |
Botulinum toxin type A |
[13] 2, 5, 6, 7, 13, 15, 17, 36, 51, 70, 113, 149, 226 |
146 | Systemic lupus erythematosus 2 genes, 5 drugs (DrugBank), 16 diseases shown |
[2] GRIN2A, GRIN2B |
D02780 |
Acamprosate |
[2] 6, 206 |
D07058 |
D00777 |
Amantadine |
[4] 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
D04905 |
Memantine |
[7] 2, 6, 8, 13, 49, 127, 205 |
D08174 |
147 | Taste transduction 20 genes, 28 drugs (DrugBank), 33 diseases shown |
[1] CACNA1C |
D00349 |
Isradipine |
[1] 6 |
[10] CACNA1C, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, SCN2A, SCN3A, SCN9A |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[1] CHRM3 |
D01699 |
Darifenacin |
[2] 6, 13 |
D03654 |
D07226 |
Fesoterodine |
[1] 6 |
D00540 |
Glycopyrronium |
[1] 6 |
D10938 |
D02212 |
Ipratropium |
[2] 6, 86 |
D00465 |
Oxybutynin |
[1] 6 |
D00722 |
D00525 |
Pilocarpine |
[3] 6, 53, 299 |
D02200 |
D05478 |
D01269 |
Solifenacin |
[1] 6 |
D08522 |
D00787 |
Trihexyphenidyl |
[2] 5, 6 |
D08638 |
D00397 |
Tropicamide |
[2] 6, 19 |
[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 |
D00280 |
Clonazepam |
[1] 6 |
D02624 |
Eszopiclone |
[3] 6, 13, 46 |
D00697 |
Flumazenil |
[5] 6, 13, 17, 18, 206 |
D00550 |
Midazolam |
[10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
D00549 |
Propofol |
[8] 6, 21, 22, 34, 46, 84, 98, 296 |
D00706 |
Zolpidem |
[2] 5, 6 |
D08690 |
D01372 |
Zopiclone |
[1] 6 |
[1] HTR1A |
D01164 |
Aripiprazole |
[2] 6, 206 |
D00702 |
Buspirone |
[2] 6, 51 |
D07593 |
D09397 |
Pardoprunox |
[1] 6 |
[2] HTR1B, HTR1D |
D00415 |
Zolmitriptan |
[1] 6 |
[5] HTR3A, HTR3B, HTR3C, HTR3D, HTR3E |
D00283 |
Clozapine |
[1] 6 |
[1] PDE1B |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
[3] SCN2A, SCN3A, SCN9A |
D00638 |
Flecainide |
[1] 6 |
D07962 |
D00358 |
Lidocaine |
[10] 6, 13, 46, 84, 86, 97, 168, 226, 231, 256 |
D02086 |
D08127 |
D01768 |
Oxybuprocaine |
[1] 6 |
D08319 |
D00538 |
Zonisamide |
[1] 6 |
148 | Terpenoid backbone biosynthesis 2 genes, 4 drugs (DrugBank), 30 diseases shown |
[1] FDPS |
D01968 |
Zoledronic acid |
[11] 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333 |
D06378 |
D06379 |
D08689 |
[1] HMGCR |
D00359 |
Lovastatin |
[10] 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 |
D01915 |
Rosuvastatin |
[8] 6, 46, 49, 51, 79, 96, 271, 299 |
D08492 |
D00434 |
Simvastatin |
[19] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
149 | Thermogenesis 5 genes, 9 drugs (DrugBank), 42 diseases shown |
[1] ADRB3 |
D02349 |
Dipivefrin |
[1] 6 |
D01277 |
Droxidopa |
[3] 5, 6, 17 |
D00095 |
Epinephrine |
[9] 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
D09535 |
Mirabegron |
[3] 6, 13, 226 |
D00483 |
Propranolol |
[5] 6, 158, 167, 227, 278 |
D08443 |
[1] CNR1 |
D10915 |
Cannabidiol |
[14] 2, 6, 13, 46, 95, 96, 97, 140, 144, 145, 157, 158, 193, 271 |
D05099 |
Nabilone |
[2] 6, 13 |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
150 | Thyroid cancer 1 gene, 1 drug (DrugBank), 17 diseases shown |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
151 | Thyroid hormone signaling pathway 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
152 | Tight junction 4 genes, 4 drugs (DrugBank), 22 diseases shown |
[1] CACNA1D |
D00349 |
Isradipine |
[1] 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[2] PRKAA1, PRKAA2 |
D00944 |
Metformin |
[17] 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
153 | TNF signaling pathway 1 gene, 1 drug (DrugBank), 13 diseases shown |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
154 | Transcriptional misregulation in cancer 2 genes, 4 drugs (DrugBank), 21 diseases shown |
[1] GRIA3 |
D08964 |
Perampanel |
[3] 2, 6, 144 |
D02696 |
Talampanel |
[2] 2, 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
155 | Tryptophan metabolism 3 genes, 8 drugs (DrugBank), 9 diseases shown |
[1] DDC |
D03082 |
Benserazide |
[1] 6 |
D00558 |
Carbidopa |
[8] 2, 4, 6, 13, 17, 90, 164, 201 |
[1] MAOA |
D02561 |
Moclobemide |
[1] 6 |
[2] MAOA, MAOB |
D02579 |
Iproniazid |
[1] 6 |
D00505 |
Phenelzine |
[1] 6 |
D08349 |
[1] MAOB |
D02562 |
Rasagiline |
[4] 2, 5, 6, 17 |
D08469 |
D10829 |
D10158 |
Safinamide |
[2] 6, 17 |
D00785 |
Selegiline |
[1] 6 |
D03731 |
156 | Tuberculosis 2 genes, 3 drugs (DrugBank), 16 diseases shown |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
[1] VDR |
D00188 |
Cholecalciferol |
[15] 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 |
D00299 |
Dihydrotachysterol |
[1] 6 |
157 | Type II diabetes mellitus 5 genes, 4 drugs (DrugBank), 6 diseases shown |
[2] ABCC8, KCNJ11 |
D00594 |
Repaglinide |
[2] 6, 299 |
[2] CACNA1C, CACNA1D |
D00349 |
Isradipine |
[1] 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
[1] CACNA1G |
D00538 |
Zonisamide |
[1] 6 |
158 | Tyrosine metabolism 4 genes, 11 drugs (DrugBank), 11 diseases shown |
[1] COMT |
D00781 |
Entacapone |
[2] 6, 17 |
D10825 |
Opicapone |
[1] 6 |
D00786 |
Tolcapone |
[3] 6, 28, 127 |
[1] DDC |
D03082 |
Benserazide |
[1] 6 |
D00558 |
Carbidopa |
[8] 2, 4, 6, 13, 17, 90, 164, 201 |
[1] MAOA |
D02561 |
Moclobemide |
[1] 6 |
[2] MAOA, MAOB |
D02579 |
Iproniazid |
[1] 6 |
D00505 |
Phenelzine |
[1] 6 |
D08349 |
[1] MAOB |
D02562 |
Rasagiline |
[4] 2, 5, 6, 17 |
D08469 |
D10829 |
D10158 |
Safinamide |
[2] 6, 17 |
D00785 |
Selegiline |
[1] 6 |
D03731 |
159 | Ubiquinone and other terpenoid-quinone biosynthesis 2 genes, 1 drug (DrugBank), 10 diseases shown |
[2] NQO1, VKORC1 |
D00564 |
Warfarin |
[10] 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 |
D01280 |
D08682 |
160 | Vascular smooth muscle contraction 8 genes, 14 drugs (DrugBank), 21 diseases shown |
[1] ADORA2A |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
D04641 |
Istradefylline |
[1] 6 |
D09717 |
Preladenant |
[1] 6 |
D10174 |
Tozadenant |
[1] 6 |
[1] ADRA1A |
D01965 |
Silodosin |
[2] 6, 13 |
[3] ADRA1A, ADRA1B, ADRA1D |
D00255 |
Carvedilol |
[4] 6, 57, 86, 113 |
D03415 |
D02349 |
Dipivefrin |
[1] 6 |
D01277 |
Droxidopa |
[3] 5, 6, 17 |
D00095 |
Epinephrine |
[9] 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
D02268 |
Ergoloid mesylate |
[1] 6 |
D01307 |
Midodrine |
[3] 6, 17, 58 |
D08220 |
D00610 |
Terazosin |
[1] 6 |
D08569 |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00349 |
Isradipine |
[1] 6 |
D00537 |
Topiramate |
[5] 6, 140, 144, 156, 193 |
161 | Vasopressin-regulated water reabsorption 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] AVPR2 |
D00291 |
Desmopressin |
[6] 6, 64, 72, 75, 225, 288 |
D02235 |
162 | VEGF signaling pathway 2 genes, 2 drugs (DrugBank), 14 diseases shown |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
163 | Vibrio cholerae infection 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] SLC12A2 |
D00247 |
Bumetanide |
[2] 6, 158 |
164 | Viral carcinogenesis 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |
165 | Viral myocarditis 1 gene, 2 drugs (DrugBank), 6 diseases shown |
[1] ABL1 |
D08953 |
Nilotinib |
[5] 6, 8, 34, 51, 86 |
D09664 |
Saracatinib |
[2] 6, 89 |
166 | Yersinia infection 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] SRC |
D09664 |
Saracatinib |
[2] 6, 89 |