No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * [Number of genes] |
KEGG DRUG * |
DrugBank |
Disease ID * [Number of diseases] |
1 | Adherens junction 2 genes, 1 drug (DrugBank), 3 diseases shown |
[2] EGFR, ERBB2 |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
2 | Alcoholism 2 genes, 4 drugs (DrugBank), 5 diseases shown |
[2] DRD1, DRD2 |
D00633 |
Dopamine |
[3] 6, 7, 74 |
D07870 |
[1] DRD2 |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
D00784 |
Ropinirole |
[3] 6, 74, 309 |
D08489 |
3 | Amphetamine addiction 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] DRD1 |
D00633 |
Dopamine |
[3] 6, 7, 74 |
D07870 |
4 | Bladder cancer 2 genes, 1 drug (DrugBank), 3 diseases shown |
[2] EGFR, ERBB2 |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
5 | Breast cancer 4 genes, 2 drugs (DrugBank), 3 diseases shown |
[2] EGFR, ERBB2 |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
[2] ESR1, ESR2 |
D00962 |
Clomifene |
[1] 74 |
D07726 |
6 | Calcium signaling pathway 4 genes, 2 drugs (DrugBank), 5 diseases shown |
[2] DRD1, DRD5 |
D00633 |
Dopamine |
[3] 6, 7, 74 |
D07870 |
[2] EGFR, ERBB2 |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
7 | cAMP signaling pathway 6 genes, 5 drugs (DrugBank), 6 diseases shown |
[3] DRD1, DRD2, DRD5 |
D00633 |
Dopamine |
[3] 6, 7, 74 |
D07870 |
[1] DRD2 |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
D00784 |
Ropinirole |
[3] 6, 74, 309 |
D08489 |
[3] SSTR1, SSTR2, SSTR5 |
D10147 |
Pasireotide |
[3] 67, 74, 75 |
8 | Central carbon metabolism in cancer 2 genes, 1 drug (DrugBank), 3 diseases shown |
[2] EGFR, ERBB2 |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
9 | Choline metabolism in cancer 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
10 | Cocaine addiction 2 genes, 4 drugs (DrugBank), 5 diseases shown |
[2] DRD1, DRD2 |
D00633 |
Dopamine |
[3] 6, 7, 74 |
D07870 |
[1] DRD2 |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
D00784 |
Ropinirole |
[3] 6, 74, 309 |
D08489 |
11 | Colorectal cancer 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
12 | Cushing syndrome 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
13 | Cytokine-cytokine receptor interaction 2 genes, 3 drugs (DrugBank), 19 diseases shown |
[1] GHR |
D02691 |
Somatotropin |
[18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
[1] PRL |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
14 | Dopaminergic synapse 5 genes, 4 drugs (DrugBank), 5 diseases shown |
[5] DRD1, DRD2, DRD3, DRD4, DRD5 |
D00633 |
Dopamine |
[3] 6, 7, 74 |
D07870 |
[1] DRD2 |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
[3] DRD2, DRD3, DRD4 |
D00784 |
Ropinirole |
[3] 6, 74, 309 |
D08489 |
15 | EGFR tyrosine kinase inhibitor resistance 2 genes, 1 drug (DrugBank), 3 diseases shown |
[2] EGFR, ERBB2 |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
16 | Endocrine and other factor-regulated calcium reabsorption 1 gene, 1 drug (DrugBank), 1 disease shown |
[1] ESR1 |
D00962 |
Clomifene |
[1] 74 |
D07726 |
17 | Endocrine resistance 4 genes, 2 drugs (DrugBank), 3 diseases shown |
[2] EGFR, ERBB2 |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
[2] ESR1, ESR2 |
D00962 |
Clomifene |
[1] 74 |
D07726 |
18 | Endocytosis 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
19 | Endometrial cancer 2 genes, 1 drug (DrugBank), 3 diseases shown |
[2] EGFR, ERBB2 |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
20 | Epithelial cell signaling in Helicobacter pylori infection 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
21 | ErbB signaling pathway 2 genes, 1 drug (DrugBank), 3 diseases shown |
[2] EGFR, ERBB2 |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
22 | Estrogen signaling pathway 3 genes, 2 drugs (DrugBank), 3 diseases shown |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
[2] ESR1, ESR2 |
D00962 |
Clomifene |
[1] 74 |
D07726 |
23 | Focal adhesion 2 genes, 1 drug (DrugBank), 3 diseases shown |
[2] EGFR, ERBB2 |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
24 | FoxO signaling pathway 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
25 | Gap junction 3 genes, 5 drugs (DrugBank), 6 diseases shown |
[2] DRD1, DRD2 |
D00633 |
Dopamine |
[3] 6, 7, 74 |
D07870 |
[1] DRD2 |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
D00784 |
Ropinirole |
[3] 6, 74, 309 |
D08489 |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
26 | Gastric acid secretion 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] SSTR2 |
D10147 |
Pasireotide |
[3] 67, 74, 75 |
27 | Gastric cancer 2 genes, 1 drug (DrugBank), 3 diseases shown |
[2] EGFR, ERBB2 |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
28 | Glioma 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
29 | GnRH secretion 1 gene, 1 drug (DrugBank), 1 disease shown |
[1] ESR2 |
D00962 |
Clomifene |
[1] 74 |
D07726 |
30 | GnRH signaling pathway 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
31 | Growth hormone synthesis, secretion and action 5 genes, 2 drugs (DrugBank), 19 diseases shown |
[1] GHR |
D02691 |
Somatotropin |
[18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
[4] SSTR1, SSTR2, SSTR3, SSTR5 |
D10147 |
Pasireotide |
[3] 67, 74, 75 |
32 | Hepatitis C 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
33 | Hepatocellular carcinoma 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
34 | HIF-1 signaling pathway 2 genes, 1 drug (DrugBank), 3 diseases shown |
[2] EGFR, ERBB2 |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
35 | Human cytomegalovirus infection 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
36 | Human papillomavirus infection 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
37 | JAK-STAT signaling pathway 3 genes, 4 drugs (DrugBank), 20 diseases shown |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
[1] GHR |
D02691 |
Somatotropin |
[18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
[1] PRL |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
38 | MAPK signaling pathway 2 genes, 1 drug (DrugBank), 3 diseases shown |
[2] EGFR, ERBB2 |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
39 | Melanoma 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
40 | MicroRNAs in cancer 2 genes, 1 drug (DrugBank), 3 diseases shown |
[2] EGFR, ERBB2 |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
41 | Morphine addiction 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] DRD1 |
D00633 |
Dopamine |
[3] 6, 7, 74 |
D07870 |
42 | Neuroactive ligand-receptor interaction 12 genes, 7 drugs (DrugBank), 36 diseases shown |
[5] DRD1, DRD2, DRD3, DRD4, DRD5 |
D00633 |
Dopamine |
[3] 6, 7, 74 |
D07870 |
[3] DRD2, DRD3, DRD4 |
D00784 |
Ropinirole |
[3] 6, 74, 309 |
D08489 |
[2] DRD2, PRL |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
[1] GHR |
D02691 |
Somatotropin |
[18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
[1] NR3C1 |
D00292 |
Dexamethasone |
[20] 13, 16, 28, 35, 46, 53, 63, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 222, 296, 299 |
D00975 |
D01510 |
D01615 |
D01632 |
D01948 |
D02174 |
D02591 |
D02592 |
[4] SSTR1, SSTR2, SSTR3, SSTR5 |
D10147 |
Pasireotide |
[3] 67, 74, 75 |
43 | Non-small cell lung cancer 2 genes, 1 drug (DrugBank), 3 diseases shown |
[2] EGFR, ERBB2 |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
44 | Oxytocin signaling pathway 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
45 | Pancreatic cancer 2 genes, 1 drug (DrugBank), 3 diseases shown |
[2] EGFR, ERBB2 |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
46 | Parathyroid hormone synthesis, secretion and action 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
47 | Parkinson disease 2 genes, 4 drugs (DrugBank), 5 diseases shown |
[2] DRD1, DRD2 |
D00633 |
Dopamine |
[3] 6, 7, 74 |
D07870 |
[1] DRD2 |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
D00784 |
Ropinirole |
[3] 6, 74, 309 |
D08489 |
48 | Pathways in cancer 4 genes, 2 drugs (DrugBank), 3 diseases shown |
[2] EGFR, ERBB2 |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
[2] ESR1, ESR2 |
D00962 |
Clomifene |
[1] 74 |
D07726 |
49 | PD-L1 expression and PD-1 checkpoint pathway in cancer 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
50 | Phospholipase D signaling pathway 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
51 | PI3K-Akt signaling pathway 4 genes, 4 drugs (DrugBank), 20 diseases shown |
[2] EGFR, ERBB2 |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
[1] GHR |
D02691 |
Somatotropin |
[18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
[1] PRL |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
52 | Platinum drug resistance 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] ERBB2 |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
53 | Prolactin signaling pathway 3 genes, 3 drugs (DrugBank), 3 diseases shown |
[2] ESR1, ESR2 |
D00962 |
Clomifene |
[1] 74 |
D07726 |
[1] PRL |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
54 | Prostate cancer 2 genes, 1 drug (DrugBank), 3 diseases shown |
[2] EGFR, ERBB2 |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
55 | Proteoglycans in cancer 3 genes, 2 drugs (DrugBank), 3 diseases shown |
[2] EGFR, ERBB2 |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
[1] ESR1 |
D00962 |
Clomifene |
[1] 74 |
D07726 |
56 | Rap1 signaling pathway 2 genes, 5 drugs (DrugBank), 6 diseases shown |
[1] DRD2 |
D00780 |
Bromocriptine |
[2] 6, 74 |
D03165 |
D00987 |
Cabergoline |
[3] 6, 74, 75 |
D00633 |
Dopamine |
[3] 6, 7, 74 |
D07870 |
D00784 |
Ropinirole |
[3] 6, 74, 309 |
D08489 |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
57 | Ras signaling pathway 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
58 | Regulation of actin cytoskeleton 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
59 | Relaxin signaling pathway 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
60 | Shigellosis 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] EGFR |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |
61 | Thyroid hormone signaling pathway 1 gene, 1 drug (DrugBank), 1 disease shown |
[1] ESR1 |
D00962 |
Clomifene |
[1] 74 |
D07726 |
62 | Tight junction 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] ERBB2 |
D04024 |
Lapatinib |
[3] 34, 74, 75 |
D08108 |