No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * [Number of genes] |
KEGG DRUG * |
DrugBank |
Disease ID * [Number of diseases] |
1 | Adherens junction 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
2 | Alcoholism 6 genes, 2 drugs (DrugBank), 9 diseases shown |
[1] ADORA2A |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
3 | Aldosterone synthesis and secretion 2 genes, 3 drugs (DrugBank), 17 diseases shown |
[1] MC2R |
D00146 |
Corticotropin |
[12] 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
D00284 |
Tetracosactide |
[5] 78, 83, 113, 145, 222 |
[1] PDE2A |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
4 | Alzheimer disease 5 genes, 1 drug (DrugBank), 9 diseases shown |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
5 | Amphetamine addiction 5 genes, 1 drug (DrugBank), 9 diseases shown |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
6 | AMPK signaling pathway 2 genes, 2 drugs (DrugBank), 18 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
7 | Amyotrophic lateral sclerosis (ALS) 5 genes, 1 drug (DrugBank), 9 diseases shown |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
8 | Apelin signaling pathway 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] PDE3B |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
9 | Autophagy - animal 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
10 | Breast cancer 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
11 | Calcium signaling pathway 6 genes, 2 drugs (DrugBank), 9 diseases shown |
[2] ADORA2A, PDE1B |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
[4] GRIN1, GRIN2A, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
12 | cAMP signaling pathway 18 genes, 6 drugs (DrugBank), 20 diseases shown |
[8] ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
[1] GHSR |
D10563 |
Macimorelin |
[1] 78 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
[1] MC2R |
D00146 |
Corticotropin |
[12] 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
D00284 |
Tetracosactide |
[5] 78, 83, 113, 145, 222 |
[3] SSTR1, SSTR2, SSTR5 |
D07431 |
Somatostatin |
[2] 67, 78 |
13 | cGMP-PKG signaling pathway 8 genes, 2 drugs (DrugBank), 6 diseases shown |
[5] ADORA1, PDE2A, PDE3A, PDE3B, PDE5A |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
[3] ADRA2A, ADRA2B, ADRA2C |
D00281 |
Clonidine |
[2] 6, 78 |
D00604 |
14 | Cholinergic synapse 1 gene, 1 drug (DrugBank), 9 diseases shown |
[1] ACHE |
D00670 |
Donepezil |
[9] 5, 6, 13, 46, 78, 124, 127, 156, 206 |
D07869 |
15 | Circadian entrainment 5 genes, 1 drug (DrugBank), 9 diseases shown |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
16 | Cocaine addiction 5 genes, 1 drug (DrugBank), 9 diseases shown |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
17 | Cortisol synthesis and secretion 1 gene, 2 drugs (DrugBank), 14 diseases shown |
[1] MC2R |
D00146 |
Corticotropin |
[12] 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
D00284 |
Tetracosactide |
[5] 78, 83, 113, 145, 222 |
18 | Cushing syndrome 3 genes, 3 drugs (DrugBank), 14 diseases shown |
[2] CRHR1, CRHR2 |
D03905 |
Corticorelin |
[2] 75, 78 |
[1] MC2R |
D00146 |
Corticotropin |
[12] 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
D00284 |
Tetracosactide |
[5] 78, 83, 113, 145, 222 |
19 | Cytokine-cytokine receptor interaction 1 gene, 5 drugs (DrugBank), 20 diseases shown |
[1] GHR |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
D05394 |
Pegvisomant |
[1] 78 |
D11194 |
Somapacitan |
[1] 78 |
D02691 |
Somatotropin |
[18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
D11193 |
Somavaratan |
[1] 78 |
20 | Dopaminergic synapse 2 genes, 1 drug (DrugBank), 9 diseases shown |
[2] GRIN2A, GRIN2B |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
21 | EGFR tyrosine kinase inhibitor resistance 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
22 | Endocrine resistance 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
23 | Endocytosis 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
24 | Estrogen signaling pathway 1 gene, 1 drug (DrugBank), 5 diseases shown |
[1] OPRM1 |
D01355 |
Tramadol |
[5] 46, 70, 78, 226, 271 |
D08623 |
25 | Focal adhesion 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
26 | FoxO signaling pathway 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
27 | Gastric acid secretion 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] SSTR2 |
D07431 |
Somatostatin |
[2] 67, 78 |
28 | Glioma 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
29 | Glucagon signaling pathway 2 genes, 2 drugs (DrugBank), 6 diseases shown |
[1] GCGR |
D00116 |
Glucagon |
[1] 78 |
D02118 |
[1] PDE3B |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
30 | Glutamatergic synapse 5 genes, 1 drug (DrugBank), 9 diseases shown |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
31 | Glycerophospholipid metabolism 1 gene, 1 drug (DrugBank), 9 diseases shown |
[1] ACHE |
D00670 |
Donepezil |
[9] 5, 6, 13, 46, 78, 124, 127, 156, 206 |
D07869 |
32 | Growth hormone synthesis, secretion and action 7 genes, 9 drugs (DrugBank), 21 diseases shown |
[1] GHR |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
D05394 |
Pegvisomant |
[1] 78 |
D11194 |
Somapacitan |
[1] 78 |
D02691 |
Somatotropin |
[18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
D11193 |
Somavaratan |
[1] 78 |
[1] GHRHR |
D08523 |
Somatorelin |
[2] 13, 78 |
D06655 |
Tesamorelin |
[2] 78, 265 |
[1] GHSR |
D10563 |
Macimorelin |
[1] 78 |
[4] SSTR1, SSTR2, SSTR3, SSTR5 |
D07431 |
Somatostatin |
[2] 67, 78 |
33 | Hepatocellular carcinoma 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
34 | HIF-1 signaling pathway 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
35 | Huntington disease 3 genes, 2 drugs (DrugBank), 20 diseases shown |
[2] GRIN1, GRIN2B |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
36 | Inflammatory mediator regulation of TRP channels 2 genes, 1 drug (DrugBank), 1 disease shown |
[2] TRPA1, TRPM8 |
D00064 |
Levomenthol |
[1] 78 |
37 | Insulin signaling pathway 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] PDE3B |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
38 | JAK-STAT signaling pathway 1 gene, 5 drugs (DrugBank), 20 diseases shown |
[1] GHR |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
D05394 |
Pegvisomant |
[1] 78 |
D11194 |
Somapacitan |
[1] 78 |
D02691 |
Somatotropin |
[18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
D11193 |
Somavaratan |
[1] 78 |
39 | Long-term depression 2 genes, 2 drugs (DrugBank), 7 diseases shown |
[1] CRHR1 |
D03905 |
Corticorelin |
[2] 75, 78 |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
40 | Long-term potentiation 5 genes, 1 drug (DrugBank), 9 diseases shown |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
41 | Longevity regulating pathway 2 genes, 2 drugs (DrugBank), 18 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
42 | Longevity regulating pathway - multiple species 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
43 | MAPK signaling pathway 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
44 | Melanoma 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
45 | Metabolic pathways 10 genes, 2 drugs (DrugBank), 8 diseases shown |
[1] CYP19A1 |
D00960 |
Anastrozole |
[3] 78, 86, 193 |
[9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
46 | Morphine addiction 10 genes, 2 drugs (DrugBank), 9 diseases shown |
[9] ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
[1] OPRM1 |
D01355 |
Tramadol |
[5] 46, 70, 78, 226, 271 |
D08623 |
47 | mTOR signaling pathway 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
48 | Neuroactive ligand-receptor interaction 26 genes, 21 drugs (DrugBank), 38 diseases shown |
[2] ADORA1, ADORA2A |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
[3] ADRA2A, ADRA2B, ADRA2C |
D00281 |
Clonidine |
[2] 6, 78 |
D00604 |
[2] CRHR1, CRHR2 |
D03905 |
Corticorelin |
[2] 75, 78 |
[1] GCGR |
D00116 |
Glucagon |
[1] 78 |
D02118 |
[1] GHR |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
D05394 |
Pegvisomant |
[1] 78 |
D11194 |
Somapacitan |
[1] 78 |
D02691 |
Somatotropin |
[18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
D11193 |
Somavaratan |
[1] 78 |
[1] GHRHR |
D08523 |
Somatorelin |
[2] 13, 78 |
D06655 |
Tesamorelin |
[2] 78, 265 |
[1] GHSR |
D10563 |
Macimorelin |
[1] 78 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
[1] MC2R |
D00146 |
Corticotropin |
[12] 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
D00284 |
Tetracosactide |
[5] 78, 83, 113, 145, 222 |
[1] NR3C1 |
D00088 |
Hydrocortisone |
[8] 6, 53, 75, 78, 81, 83, 97, 299 |
D00165 |
Hydrocortisone acetate |
[8] 6, 53, 75, 78, 81, 83, 97, 299 |
[1] OPRM1 |
D01355 |
Tramadol |
[5] 46, 70, 78, 226, 271 |
D08623 |
[5] SSTR1, SSTR2, SSTR3, SSTR4, SSTR5 |
D07431 |
Somatostatin |
[2] 67, 78 |
[2] THRA, THRB |
D01010 |
Levothyroxine |
[2] 49, 78 |
D08125 |
D01011 |
Liothyronine |
[3] 13, 78, 212 |
D08128 |
49 | Nicotine addiction 5 genes, 1 drug (DrugBank), 9 diseases shown |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
50 | Olfactory transduction 2 genes, 1 drug (DrugBank), 6 diseases shown |
[2] PDE1B, PDE2A |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
51 | Oocyte meiosis 2 genes, 2 drugs (DrugBank), 11 diseases shown |
[1] AR |
D00075 |
Testosterone |
[7] 1, 2, 3, 13, 78, 113, 265 |
D00957 |
D00958 |
D00959 |
D06085 |
D06087 |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
52 | Osteoclast differentiation 1 gene, 1 drug (DrugBank), 17 diseases shown |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
53 | Ovarian steroidogenesis 2 genes, 2 drugs (DrugBank), 8 diseases shown |
[1] CYP19A1 |
D00960 |
Anastrozole |
[3] 78, 86, 193 |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
54 | Parathyroid hormone synthesis, secretion and action 4 genes, 1 drug (DrugBank), 6 diseases shown |
[4] PDE4A, PDE4B, PDE4C, PDE4D |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
55 | Parkinson disease 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] ADORA2A |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
56 | Pathways in cancer 3 genes, 3 drugs (DrugBank), 21 diseases shown |
[1] AR |
D00075 |
Testosterone |
[7] 1, 2, 3, 13, 78, 113, 265 |
D00957 |
D00958 |
D00959 |
D06085 |
D06087 |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
57 | PI3K-Akt signaling pathway 2 genes, 5 drugs (DrugBank), 20 diseases shown |
[1] GHR |
D05394 |
Pegvisomant |
[1] 78 |
D11194 |
Somapacitan |
[1] 78 |
D02691 |
Somatotropin |
[18] 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
D11193 |
Somavaratan |
[1] 78 |
[2] GHR, IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
58 | PPAR signaling pathway 1 gene, 1 drug (DrugBank), 17 diseases shown |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
59 | Progesterone-mediated oocyte maturation 2 genes, 2 drugs (DrugBank), 10 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
[1] PDE3B |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
60 | Prostate cancer 2 genes, 2 drugs (DrugBank), 11 diseases shown |
[1] AR |
D00075 |
Testosterone |
[7] 1, 2, 3, 13, 78, 113, 265 |
D00957 |
D00958 |
D00959 |
D06085 |
D06087 |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
61 | Proteoglycans in cancer 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
62 | Purine metabolism 9 genes, 1 drug (DrugBank), 6 diseases shown |
[9] PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
63 | Rap1 signaling pathway 5 genes, 3 drugs (DrugBank), 13 diseases shown |
[1] ADORA2A |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
[3] GRIN1, GRIN2A, GRIN2B |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
64 | Ras signaling pathway 4 genes, 2 drugs (DrugBank), 13 diseases shown |
[3] GRIN1, GRIN2A, GRIN2B |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
65 | Regulation of lipolysis in adipocytes 2 genes, 1 drug (DrugBank), 6 diseases shown |
[2] ADORA1, PDE3B |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
66 | Renin secretion 4 genes, 1 drug (DrugBank), 6 diseases shown |
[4] ADORA1, PDE1B, PDE3A, PDE3B |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
67 | Serotonergic synapse 1 gene, 2 drugs (DrugBank), 8 diseases shown |
[1] SLC6A4 |
D00809 |
Amitriptyline |
[3] 78, 226, 299 |
D07448 |
D00326 |
Fluoxetine |
[6] 13, 17, 78, 86, 179, 206 |
D00823 |
68 | Signaling pathways regulating pluripotency of stem cells 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
69 | Sphingolipid signaling pathway 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] ADORA1 |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
70 | Steroid hormone biosynthesis 1 gene, 1 drug (DrugBank), 3 diseases shown |
[1] CYP19A1 |
D00960 |
Anastrozole |
[3] 78, 86, 193 |
71 | Synaptic vesicle cycle 2 genes, 2 drugs (DrugBank), 8 diseases shown |
[2] SLC6A2, SLC6A4 |
D00809 |
Amitriptyline |
[3] 78, 226, 299 |
D07448 |
[1] SLC6A4 |
D00326 |
Fluoxetine |
[6] 13, 17, 78, 86, 179, 206 |
D00823 |
72 | Systemic lupus erythematosus 2 genes, 1 drug (DrugBank), 9 diseases shown |
[2] GRIN2A, GRIN2B |
D00848 |
Dextromethorphan |
[9] 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
73 | Taste transduction 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] PDE1B |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |
74 | Thermogenesis 1 gene, 1 drug (DrugBank), 17 diseases shown |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
75 | Thyroid cancer 1 gene, 1 drug (DrugBank), 17 diseases shown |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
76 | Thyroid hormone signaling pathway 2 genes, 2 drugs (DrugBank), 4 diseases shown |
[2] THRA, THRB |
D01010 |
Levothyroxine |
[2] 49, 78 |
D08125 |
D01011 |
Liothyronine |
[3] 13, 78, 212 |
D08128 |
77 | Transcriptional misregulation in cancer 2 genes, 2 drugs (DrugBank), 18 diseases shown |
[1] IGF1R |
D03297 |
Mecasermin |
[6] 65, 78, 96, 168, 265, 299 |
D04870 |
[1] PPARG |
D00945 |
Pioglitazone |
[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
78 | Vascular smooth muscle contraction 1 gene, 1 drug (DrugBank), 6 diseases shown |
[1] ADORA2A |
D00528 |
Caffeine |
[6] 2, 6, 46, 78, 96, 97 |
D01453 |