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 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

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78 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY * 
 On map, Yellow: Drug target, Red: Disease-related 		  KEGG GENES * 
 [Number of genes] 		  KEGG DRUG *   DrugBank   Disease ID * 
 [Number of diseases] 
 1  Adipocytokine signaling pathway 
 2 genes, 4 drugs (DrugBank), 14 diseases shown 		  [1] JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 [1] PPARA   D01366   Bezafibrate   [5] 20, 93, 94, 160, 316 
 D11208   Elafibranor   [1] 93 
 D00565   Fenofibrate   [5] 8, 79, 93, 94, 265 
 2  African trypanosomiasis 
 2 genes, 1 drug (DrugBank), 16 diseases shown 		  [2] IL12A, IL12B   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 3  AGE-RAGE signaling pathway in diabetic complications 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 4  Allograft rejection 
 4 genes, 2 drugs (DrugBank), 28 diseases shown 		  [2] CD80, CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 [2] IL12A, IL12B   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 5  Amoebiasis 
 2 genes, 1 drug (DrugBank), 16 diseases shown 		  [2] IL12A, IL12B   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 6  AMPK signaling pathway 
 1 gene, 1 drug (DrugBank), 17 diseases shown 		  [1] HMGCR   D00887   Atorvastatin   [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 
 D07474 
 7  Antifolate resistance 
 2 genes, 1 drug (DrugBank), 33 diseases shown 		  [2] DHFR, DHFR2   D00142   Methotrexate   [33] 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 8  Autoimmune thyroid disease 
 2 genes, 1 drug (DrugBank), 24 diseases shown 		  [2] CD80, CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 9  Bile secretion 
 2 genes, 3 drugs (DrugBank), 26 diseases shown 		  [1] HMGCR   D00887   Atorvastatin   [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 
 D07474 
 [1] NR1H4   D09360   Obeticholic acid   [3] 93, 265, 296 
 D00734   Ursodeoxycholic acid   [12] 6, 8, 20, 67, 84, 93, 94, 95, 96, 97, 234, 299 
 10  Breast cancer 
 1 gene, 1 drug (DrugBank), 7 diseases shown 		  [1] TNFSF11   D03684   Denosumab   [7] 46, 50, 93, 95, 96, 274, 299 
 11  C-type lectin receptor signaling pathway 
 3 genes, 1 drug (DrugBank), 16 diseases shown 		  [3] IL12A, IL12B, IL23A   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 12  cAMP signaling pathway 
 1 gene, 3 drugs (DrugBank), 8 diseases shown 		  [1] PPARA   D01366   Bezafibrate   [5] 20, 93, 94, 160, 316 
 D11208   Elafibranor   [1] 93 
 D00565   Fenofibrate   [5] 8, 79, 93, 94, 265 
 13  Cell adhesion molecules (CAMs) 
 2 genes, 1 drug (DrugBank), 24 diseases shown 		  [2] CD80, CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 14  Chagas disease (American trypanosomiasis) 
 3 genes, 2 drugs (DrugBank), 16 diseases shown 		  [1] ACE   D00623   Moexipril   [1] 93 
 D08225 
 [2] IL12A, IL12B   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 15  Chemokine signaling pathway 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 16  Cholinergic synapse 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 17  Cytokine-cytokine receptor interaction 
 4 genes, 2 drugs (DrugBank), 19 diseases shown 		  [3] IL12A, IL12B, IL23A   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 [1] TNFSF11   D03684   Denosumab   [7] 46, 50, 93, 95, 96, 274, 299 
 18  EGFR tyrosine kinase inhibitor resistance 
 2 genes, 1 drug (DrugBank), 8 diseases shown 		  [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 19  Epstein-Barr virus infection 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK1   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 20  Fat digestion and absorption 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] NPC1L1   D01966   Ezetimibe   [4] 49, 79, 93, 260 
 21  Folate biosynthesis 
 2 genes, 1 drug (DrugBank), 33 diseases shown 		  [2] DHFR, DHFR2   D00142   Methotrexate   [33] 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 22  Gap junction 
 9 genes, 1 drug (DrugBank), 5 diseases shown 		  [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8   D00570   Colchicine   [5] 2, 42, 56, 93, 266 
 23  Glucagon signaling pathway 
 1 gene, 3 drugs (DrugBank), 8 diseases shown 		  [1] PPARA   D01366   Bezafibrate   [5] 20, 93, 94, 160, 316 
 D11208   Elafibranor   [1] 93 
 D00565   Fenofibrate   [5] 8, 79, 93, 94, 265 
 24  Graft-versus-host disease 
 2 genes, 1 drug (DrugBank), 24 diseases shown 		  [2] CD80, CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 25  Growth hormone synthesis, secretion and action 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 26  Hematopoietic cell lineage 
 1 gene, 1 drug (DrugBank), 42 diseases shown 		  [1] MS4A1   D02994   Rituximab   [42] 11, 13, 14, 17, 35, 36, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 223, 229, 256, 271, 283, 284, 285, 288, 300, 331 
 27  Hepatitis B 
 2 genes, 1 drug (DrugBank), 8 diseases shown 		  [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 28  Hepatitis C 
 2 genes, 4 drugs (DrugBank), 14 diseases shown 		  [1] JAK1   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 [1] PPARA   D01366   Bezafibrate   [5] 20, 93, 94, 160, 316 
 D11208   Elafibranor   [1] 93 
 D00565   Fenofibrate   [5] 8, 79, 93, 94, 265 
 29  Herpes simplex virus 1 infection 
 4 genes, 2 drugs (DrugBank), 19 diseases shown 		  [2] IL12A, IL12B   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 30  Human cytomegalovirus infection 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK1   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 31  Human papillomavirus infection 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK1   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 32  Human T-cell leukemia virus 1 infection 
 2 genes, 3 drugs (DrugBank), 19 diseases shown 		  [1] FDPS   D00942   Risedronic acid   [7] 46, 66, 93, 95, 96, 113, 274 
 D03234 
 D08484 
 D01968   Zoledronic acid   [11] 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333 
 D06378 
 D06379 
 D08689 
 [1] JAK1   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 33  Hypertrophic cardiomyopathy (HCM) 
 1 gene, 1 drug (DrugBank), 1 disease shown 		  [1] ACE   D00623   Moexipril   [1] 93 
 D08225 
 34  Inflammatory bowel disease (IBD) 
 3 genes, 1 drug (DrugBank), 16 diseases shown 		  [3] IL12A, IL12B, IL23A   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 35  Influenza A 
 5 genes, 4 drugs (DrugBank), 26 diseases shown 		  [1] FDPS   D00942   Risedronic acid   [7] 46, 66, 93, 95, 96, 113, 274 
 D03234 
 D08484 
 D01968   Zoledronic acid   [11] 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333 
 D06378 
 D06379 
 D08689 
 [2] IL12A, IL12B   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 36  Insulin resistance 
 1 gene, 3 drugs (DrugBank), 8 diseases shown 		  [1] PPARA   D01366   Bezafibrate   [5] 20, 93, 94, 160, 316 
 D11208   Elafibranor   [1] 93 
 D00565   Fenofibrate   [5] 8, 79, 93, 94, 265 
 37  Intestinal immune network for IgA production 
 2 genes, 1 drug (DrugBank), 24 diseases shown 		  [2] CD80, CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 38  JAK-STAT signaling pathway 
 5 genes, 2 drugs (DrugBank), 19 diseases shown 		  [3] IL12A, IL12B, IL23A   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 39  Kaposi sarcoma-associated herpesvirus infection 
 3 genes, 2 drugs (DrugBank), 26 diseases shown 		  [1] CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 40  Legionellosis 
 2 genes, 1 drug (DrugBank), 16 diseases shown 		  [2] IL12A, IL12B   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 41  Leishmaniasis 
 4 genes, 2 drugs (DrugBank), 19 diseases shown 		  [2] IL12A, IL12B   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 42  Malaria 
 1 gene, 1 drug (DrugBank), 16 diseases shown 		  [1] IL12A   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 43  Measles 
 3 genes, 2 drugs (DrugBank), 19 diseases shown 		  [2] IL12A, IL12B   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 [1] JAK1   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 44  Metabolic pathways 
 4 genes, 4 drugs (DrugBank), 48 diseases shown 		  [2] DHFR, DHFR2   D00142   Methotrexate   [33] 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 [1] FDPS   D00942   Risedronic acid   [7] 46, 66, 93, 95, 96, 113, 274 
 D03234 
 D08484 
 D01968   Zoledronic acid   [11] 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333 
 D06378 
 D06379 
 D08689 
 [1] HMGCR   D00887   Atorvastatin   [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 
 D07474 
 45  Necroptosis 
 2 genes, 1 drug (DrugBank), 8 diseases shown 		  [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 46  Neuroactive ligand-receptor interaction 
 1 gene, 1 drug (DrugBank), 10 diseases shown 		  [1] NR3C1   D00246   Budesonide   [10] 66, 85, 93, 94, 95, 96, 97, 98, 228, 299 
 47  NF-kappa B signaling pathway 
 1 gene, 1 drug (DrugBank), 7 diseases shown 		  [1] TNFSF11   D03684   Denosumab   [7] 46, 50, 93, 95, 96, 274, 299 
 48  NOD-like receptor signaling pathway 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK1   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 49  Non-alcoholic fatty liver disease (NAFLD) 
 1 gene, 3 drugs (DrugBank), 8 diseases shown 		  [1] PPARA   D01366   Bezafibrate   [5] 20, 93, 94, 160, 316 
 D11208   Elafibranor   [1] 93 
 D00565   Fenofibrate   [5] 8, 79, 93, 94, 265 
 50  One carbon pool by folate 
 2 genes, 1 drug (DrugBank), 33 diseases shown 		  [2] DHFR, DHFR2   D00142   Methotrexate   [33] 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 
 D02115 
 51  Osteoclast differentiation 
 2 genes, 2 drugs (DrugBank), 12 diseases shown 		  [1] JAK1   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 [1] TNFSF11   D03684   Denosumab   [7] 46, 50, 93, 95, 96, 274, 299 
 52  Pancreatic cancer 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK1   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 53  Parathyroid hormone synthesis, secretion and action 
 1 gene, 1 drug (DrugBank), 7 diseases shown 		  [1] TNFSF11   D03684   Denosumab   [7] 46, 50, 93, 95, 96, 274, 299 
 54  Pathogenic Escherichia coli infection 
 9 genes, 1 drug (DrugBank), 5 diseases shown 		  [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8   D00570   Colchicine   [5] 2, 42, 56, 93, 266 
 55  Pathways in cancer 
 5 genes, 2 drugs (DrugBank), 19 diseases shown 		  [3] IL12A, IL12B, IL23A   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 56  PD-L1 expression and PD-1 checkpoint pathway in cancer 
 2 genes, 1 drug (DrugBank), 8 diseases shown 		  [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 57  Pertussis 
 3 genes, 1 drug (DrugBank), 16 diseases shown 		  [3] IL12A, IL12B, IL23A   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 58  Phagosome 
 9 genes, 1 drug (DrugBank), 5 diseases shown 		  [9] TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8   D00570   Colchicine   [5] 2, 42, 56, 93, 266 
 59  PI3K-Akt signaling pathway 
 2 genes, 1 drug (DrugBank), 8 diseases shown 		  [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 60  PPAR signaling pathway 
 1 gene, 3 drugs (DrugBank), 8 diseases shown 		  [1] PPARA   D01366   Bezafibrate   [5] 20, 93, 94, 160, 316 
 D11208   Elafibranor   [1] 93 
 D00565   Fenofibrate   [5] 8, 79, 93, 94, 265 
 61  Prolactin signaling pathway 
 2 genes, 2 drugs (DrugBank), 12 diseases shown 		  [1] JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 [1] TNFSF11   D03684   Denosumab   [7] 46, 50, 93, 95, 96, 274, 299 
 62  Proteoglycans in cancer 
 1 gene, 1 drug (DrugBank), 16 diseases shown 		  [1] IL12B   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 63  Renin secretion 
 1 gene, 1 drug (DrugBank), 1 disease shown 		  [1] ACE   D00623   Moexipril   [1] 93 
 D08225 
 64  Renin-angiotensin system 
 1 gene, 1 drug (DrugBank), 1 disease shown 		  [1] ACE   D00623   Moexipril   [1] 93 
 D08225 
 65  Rheumatoid arthritis 
 4 genes, 3 drugs (DrugBank), 31 diseases shown 		  [2] CD80, CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 [1] IL23A   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 [1] TNFSF11   D03684   Denosumab   [7] 46, 50, 93, 95, 96, 274, 299 
 66  RIG-I-like receptor signaling pathway 
 2 genes, 1 drug (DrugBank), 16 diseases shown 		  [2] IL12A, IL12B   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 67  Signaling pathways regulating pluripotency of stem cells 
 2 genes, 1 drug (DrugBank), 8 diseases shown 		  [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 68  Systemic lupus erythematosus 
 2 genes, 1 drug (DrugBank), 24 diseases shown 		  [2] CD80, CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 69  Terpenoid backbone biosynthesis 
 2 genes, 3 drugs (DrugBank), 24 diseases shown 		  [1] FDPS   D00942   Risedronic acid   [7] 46, 66, 93, 95, 96, 113, 274 
 D03234 
 D08484 
 D01968   Zoledronic acid   [11] 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333 
 D06378 
 D06379 
 D08689 
 [1] HMGCR   D00887   Atorvastatin   [17] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 
 D07474 
 70  Th1 and Th2 cell differentiation 
 4 genes, 2 drugs (DrugBank), 19 diseases shown 		  [2] IL12A, IL12B   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 71  Th17 cell differentiation 
 3 genes, 2 drugs (DrugBank), 19 diseases shown 		  [1] IL23A   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 72  Toll-like receptor signaling pathway 
 4 genes, 2 drugs (DrugBank), 28 diseases shown 		  [2] CD80, CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 [2] IL12A, IL12B   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 73  Toxoplasmosis 
 4 genes, 2 drugs (DrugBank), 19 diseases shown 		  [2] IL12A, IL12B   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 74  Transcriptional misregulation in cancer 
 1 gene, 1 drug (DrugBank), 24 diseases shown 		  [1] CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 75  Tuberculosis 
 5 genes, 2 drugs (DrugBank), 19 diseases shown 		  [3] IL12A, IL12B, IL23A   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 [2] JAK1, JAK2   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 76  Type I diabetes mellitus 
 4 genes, 2 drugs (DrugBank), 28 diseases shown 		  [2] CD80, CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 
 [2] IL12A, IL12B   D09214   Ustekinumab   [16] 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 
 77  Viral carcinogenesis 
 1 gene, 1 drug (DrugBank), 8 diseases shown 		  [1] JAK1   D10308   Baricitinib   [8] 41, 46, 49, 50, 93, 107, 265, 325 
 78  Viral myocarditis 
 2 genes, 1 drug (DrugBank), 24 diseases shown 		  [2] CD80, CD86   D03203   Abatacept   [24] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 

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