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 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

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123 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY * 
 On map, Yellow: Drug target, Red: Disease-related 		  KEGG GENES * 
 [Number of genes] 		  KEGG DRUG *   DrugBank   Disease ID * 
 [Number of diseases] 
 1  Acute myeloid leukemia 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 2  Adipocytokine signaling pathway 
 2 genes, 2 drugs (DrugBank), 52 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 3  Adrenergic signaling in cardiomyocytes 
 1 gene, 1 drug (DrugBank), 18 diseases shown 		  [1] AGTR1   D00357   Losartan   [18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 4  African trypanosomiasis 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 5  AGE-RAGE signaling pathway in diabetic complications 
 2 genes, 2 drugs (DrugBank), 35 diseases shown 		  [1] AGTR1   D00357   Losartan   [18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 6  Aldosterone synthesis and secretion 
 1 gene, 1 drug (DrugBank), 18 diseases shown 		  [1] AGTR1   D00357   Losartan   [18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 7  Allograft rejection 
 2 genes, 3 drugs (DrugBank), 24 diseases shown 		  [1] IL5   D04923   Mepolizumab   [4] 44, 45, 98, 162 
 D08985   Reslizumab   [3] 44, 45, 98 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 8  Alzheimer disease 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 9  Amoebiasis 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 10  AMPK signaling pathway 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 11  Amyotrophic lateral sclerosis (ALS) 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 12  Antifolate resistance 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 13  Antigen processing and presentation 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 14  Apelin signaling pathway 
 2 genes, 2 drugs (DrugBank), 45 diseases shown 		  [1] AGTR1   D00357   Losartan   [18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 15  Apoptosis 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 16  Asthma 
 3 genes, 4 drugs (DrugBank), 27 diseases shown 		  [1] FCER1A   D05251   Omalizumab   [6] 53, 65, 98, 162, 226, 299 
 [1] IL5   D04923   Mepolizumab   [4] 44, 45, 98, 162 
 D08985   Reslizumab   [3] 44, 45, 98 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 17  Autoimmune thyroid disease 
 1 gene, 2 drugs (DrugBank), 4 diseases shown 		  [1] IL5   D04923   Mepolizumab   [4] 44, 45, 98, 162 
 D08985   Reslizumab   [3] 44, 45, 98 
 18  Autophagy - animal 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 19  Autophagy - other 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 20  Breast cancer 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 21  C-type lectin receptor signaling pathway 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 22  Calcium signaling pathway 
 6 genes, 3 drugs (DrugBank), 19 diseases shown 		  [1] AGTR1   D00357   Losartan   [18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 [4] CHRM1, CHRM2, CHRM3, CHRM5   D01000   Bethanechol   [1] 98 
 [1] CYSLTR1   D00529   Montelukast   [5] 13, 46, 85, 98, 228 
 D08229 
 23  cAMP signaling pathway 
 2 genes, 1 drug (DrugBank), 1 disease shown 		  [2] CHRM1, CHRM2   D01000   Bethanechol   [1] 98 
 24  Cellular senescence 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 25  Central carbon metabolism in cancer 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 26  cGMP-PKG signaling pathway 
 1 gene, 1 drug (DrugBank), 18 diseases shown 		  [1] AGTR1   D00357   Losartan   [18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 27  Chagas disease (American trypanosomiasis) 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 28  Choline metabolism in cancer 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 29  Cholinergic synapse 
 5 genes, 1 drug (DrugBank), 1 disease shown 		  [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5   D01000   Bethanechol   [1] 98 
 30  Collecting duct acid secretion 
 2 genes, 4 drugs (DrugBank), 20 diseases shown 		  [2] ATP4A, ATP4B   D08903   Dexlansoprazole   [1] 98 
 D01984   Esomeprazole   [6] 6, 46, 86, 98, 298, 299 
 D04056 
 D07917 
 D09339 
 D00355   Lansoprazole   [6] 63, 71, 98, 166, 222, 299 
 D00455   Omeprazole   [15] 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 
 D01207 
 D05259 
 D05261 
 31  Colorectal cancer 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 32  Cortisol synthesis and secretion 
 1 gene, 1 drug (DrugBank), 18 diseases shown 		  [1] AGTR1   D00357   Losartan   [18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 33  Cushing syndrome 
 1 gene, 1 drug (DrugBank), 18 diseases shown 		  [1] AGTR1   D00357   Losartan   [18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 34  Cytokine-cytokine receptor interaction 
 3 genes, 4 drugs (DrugBank), 24 diseases shown 		  [1] IL4R   D10354   Dupilumab   [1] 98 
 [1] IL5   D04923   Mepolizumab   [4] 44, 45, 98, 162 
 D08985   Reslizumab   [3] 44, 45, 98 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 35  Dilated cardiomyopathy (DCM) 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 36  EGFR tyrosine kinase inhibitor resistance 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 37  Endocrine resistance 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 38  Epstein-Barr virus infection 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 39  ErbB signaling pathway 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 40  Fc epsilon RI signaling pathway 
 3 genes, 4 drugs (DrugBank), 27 diseases shown 		  [1] FCER1A   D05251   Omalizumab   [6] 53, 65, 98, 162, 226, 299 
 [1] IL5   D04923   Mepolizumab   [4] 44, 45, 98, 162 
 D08985   Reslizumab   [3] 44, 45, 98 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 41  Fluid shear stress and atherosclerosis 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 42  GABAergic synapse 
 16 genes, 1 drug (DrugBank), 8 diseases shown 		  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00549   Propofol   [8] 6, 21, 22, 34, 46, 84, 98, 296 
 43  Gastric acid secretion 
 3 genes, 5 drugs (DrugBank), 20 diseases shown 		  [2] ATP4A, ATP4B   D08903   Dexlansoprazole   [1] 98 
 D01984   Esomeprazole   [6] 6, 46, 86, 98, 298, 299 
 D04056 
 D07917 
 D09339 
 D00355   Lansoprazole   [6] 63, 71, 98, 166, 222, 299 
 D00455   Omeprazole   [15] 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 
 D01207 
 D05259 
 D05261 
 [1] CHRM3   D01000   Bethanechol   [1] 98 
 44  Gastric cancer 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 45  Glioma 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 46  Graft-versus-host disease 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 47  Growth hormone synthesis, secretion and action 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 48  Hematopoietic cell lineage 
 3 genes, 4 drugs (DrugBank), 24 diseases shown 		  [1] IL4R   D10354   Dupilumab   [1] 98 
 [1] IL5   D04923   Mepolizumab   [4] 44, 45, 98, 162 
 D08985   Reslizumab   [3] 44, 45, 98 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 49  Hepatitis B 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 50  Hepatitis C 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 51  Hepatocellular carcinoma 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 52  Herpes simplex virus 1 infection 
 2 genes, 2 drugs (DrugBank), 52 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 53  HIF-1 signaling pathway 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 54  Human cytomegalovirus infection 
 2 genes, 2 drugs (DrugBank), 52 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 55  Human immunodeficiency virus 1 infection 
 2 genes, 2 drugs (DrugBank), 52 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 56  Human papillomavirus infection 
 2 genes, 2 drugs (DrugBank), 52 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 57  Human T-cell leukemia virus 1 infection 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 58  Hypertrophic cardiomyopathy (HCM) 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 59  IL-17 signaling pathway 
 2 genes, 3 drugs (DrugBank), 24 diseases shown 		  [1] IL5   D04923   Mepolizumab   [4] 44, 45, 98, 162 
 D08985   Reslizumab   [3] 44, 45, 98 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 60  Inflammatory bowel disease (IBD) 
 3 genes, 4 drugs (DrugBank), 24 diseases shown 		  [1] IL4R   D10354   Dupilumab   [1] 98 
 [1] IL5   D04923   Mepolizumab   [4] 44, 45, 98, 162 
 D08985   Reslizumab   [3] 44, 45, 98 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 61  Influenza A 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 62  Insulin resistance 
 2 genes, 2 drugs (DrugBank), 52 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 63  Insulin secretion 
 1 gene, 1 drug (DrugBank), 1 disease shown 		  [1] CHRM3   D01000   Bethanechol   [1] 98 
 64  Insulin signaling pathway 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 65  Intestinal immune network for IgA production 
 1 gene, 2 drugs (DrugBank), 4 diseases shown 		  [1] IL5   D04923   Mepolizumab   [4] 44, 45, 98, 162 
 D08985   Reslizumab   [3] 44, 45, 98 
 66  JAK-STAT signaling pathway 
 3 genes, 4 drugs (DrugBank), 39 diseases shown 		  [1] IL4R   D10354   Dupilumab   [1] 98 
 [1] IL5   D04923   Mepolizumab   [4] 44, 45, 98, 162 
 D08985   Reslizumab   [3] 44, 45, 98 
 [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 67  Kaposi sarcoma-associated herpesvirus infection 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 68  Legionellosis 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 69  Leishmaniasis 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 70  Longevity regulating pathway 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 71  Longevity regulating pathway - multiple species 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 72  Malaria 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 73  MAPK signaling pathway 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 74  Metabolic pathways 
 2 genes, 4 drugs (DrugBank), 20 diseases shown 		  [2] ATP4A, ATP4B   D08903   Dexlansoprazole   [1] 98 
 D01984   Esomeprazole   [6] 6, 46, 86, 98, 298, 299 
 D04056 
 D07917 
 D09339 
 D00355   Lansoprazole   [6] 63, 71, 98, 166, 222, 299 
 D00455   Omeprazole   [15] 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 
 D01207 
 D05259 
 D05261 
 75  MicroRNAs in cancer 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 76  Morphine addiction 
 16 genes, 1 drug (DrugBank), 8 diseases shown 		  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00549   Propofol   [8] 6, 21, 22, 34, 46, 84, 98, 296 
 77  mTOR signaling pathway 
 2 genes, 2 drugs (DrugBank), 52 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 78  Natural killer cell mediated cytotoxicity 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 79  Necroptosis 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 80  Neuroactive ligand-receptor interaction 
 24 genes, 9 drugs (DrugBank), 29 diseases shown 		  [1] AGTR1   D00357   Losartan   [18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5   D01000   Bethanechol   [1] 98 
 [1] CYSLTR1   D00529   Montelukast   [5] 13, 46, 85, 98, 228 
 D08229 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00549   Propofol   [8] 6, 21, 22, 34, 46, 84, 98, 296 
 [1] NR3C1   D00689   Beclomethasone dipropionate   [2] 97, 98 
 D07495 
 D00246   Budesonide   [10] 66, 85, 93, 94, 95, 96, 97, 98, 228, 299 
 D07981   Fluticasone   [4] 98, 228, 299, 306 
 D01708   Fluticasone propionate   [4] 98, 228, 299, 306 
 D00690   Mometasone furoate   [1] 98 
 81  NF-kappa B signaling pathway 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 82  Nicotine addiction 
 16 genes, 1 drug (DrugBank), 8 diseases shown 		  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00549   Propofol   [8] 6, 21, 22, 34, 46, 84, 98, 296 
 83  NOD-like receptor signaling pathway 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 84  Non-alcoholic fatty liver disease (NAFLD) 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 85  Osteoclast differentiation 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 86  Oxidative phosphorylation 
 2 genes, 4 drugs (DrugBank), 20 diseases shown 		  [2] ATP4A, ATP4B   D08903   Dexlansoprazole   [1] 98 
 D01984   Esomeprazole   [6] 6, 46, 86, 98, 298, 299 
 D04056 
 D07917 
 D09339 
 D00355   Lansoprazole   [6] 63, 71, 98, 166, 222, 299 
 D00455   Omeprazole   [15] 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 
 D01207 
 D05259 
 D05261 
 87  Pancreatic cancer 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 88  Pancreatic secretion 
 1 gene, 1 drug (DrugBank), 1 disease shown 		  [1] CHRM3   D01000   Bethanechol   [1] 98 
 89  Pathogenic Escherichia coli infection 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 90  Pathways in cancer 
 4 genes, 5 drugs (DrugBank), 48 diseases shown 		  [1] AGTR1   D00357   Losartan   [18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 [1] IL4R   D10354   Dupilumab   [1] 98 
 [1] IL5   D04923   Mepolizumab   [4] 44, 45, 98, 162 
 D08985   Reslizumab   [3] 44, 45, 98 
 [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 91  PD-L1 expression and PD-1 checkpoint pathway in cancer 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 92  Pertussis 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 93  Phospholipase D signaling pathway 
 3 genes, 3 drugs (DrugBank), 48 diseases shown 		  [1] AGTR1   D00357   Losartan   [18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 [1] FCER1A   D05251   Omalizumab   [6] 53, 65, 98, 162, 226, 299 
 [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 94  PI3K-Akt signaling pathway 
 4 genes, 3 drugs (DrugBank), 36 diseases shown 		  [2] CHRM1, CHRM2   D01000   Bethanechol   [1] 98 
 [1] IL4R   D10354   Dupilumab   [1] 98 
 [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 95  Prostate cancer 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 96  Proteoglycans in cancer 
 2 genes, 2 drugs (DrugBank), 52 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 97  Regulation of actin cytoskeleton 
 5 genes, 1 drug (DrugBank), 1 disease shown 		  [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5   D01000   Bethanechol   [1] 98 
 98  Renin secretion 
 1 gene, 1 drug (DrugBank), 18 diseases shown 		  [1] AGTR1   D00357   Losartan   [18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 99  Renin-angiotensin system 
 1 gene, 1 drug (DrugBank), 18 diseases shown 		  [1] AGTR1   D00357   Losartan   [18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 100  Retrograde endocannabinoid signaling 
 16 genes, 1 drug (DrugBank), 8 diseases shown 		  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00549   Propofol   [8] 6, 21, 22, 34, 46, 84, 98, 296 
 101  Rheumatoid arthritis 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 102  RIG-I-like receptor signaling pathway 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 103  Salivary secretion 
 1 gene, 1 drug (DrugBank), 1 disease shown 		  [1] CHRM3   D01000   Bethanechol   [1] 98 
 104  Serotonergic synapse 
 3 genes, 1 drug (DrugBank), 8 diseases shown 		  [3] GABRB1, GABRB2, GABRB3   D00549   Propofol   [8] 6, 21, 22, 34, 46, 84, 98, 296 
 105  Shigellosis 
 2 genes, 2 drugs (DrugBank), 52 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 106  Sphingolipid signaling pathway 
 2 genes, 2 drugs (DrugBank), 26 diseases shown 		  [1] FCER1A   D05251   Omalizumab   [6] 53, 65, 98, 162, 226, 299 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 107  Systemic lupus erythematosus 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 108  T cell receptor signaling pathway 
 2 genes, 3 drugs (DrugBank), 24 diseases shown 		  [1] IL5   D04923   Mepolizumab   [4] 44, 45, 98, 162 
 D08985   Reslizumab   [3] 44, 45, 98 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 109  Taste transduction 
 7 genes, 2 drugs (DrugBank), 8 diseases shown 		  [1] CHRM3   D01000   Bethanechol   [1] 98 
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6   D00549   Propofol   [8] 6, 21, 22, 34, 46, 84, 98, 296 
 110  TGF-beta signaling pathway 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 111  Th1 and Th2 cell differentiation 
 2 genes, 3 drugs (DrugBank), 4 diseases shown 		  [1] IL4R   D10354   Dupilumab   [1] 98 
 [1] IL5   D04923   Mepolizumab   [4] 44, 45, 98, 162 
 D08985   Reslizumab   [3] 44, 45, 98 
 112  Th17 cell differentiation 
 2 genes, 2 drugs (DrugBank), 36 diseases shown 		  [1] IL4R   D10354   Dupilumab   [1] 98 
 [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 113  Thermogenesis 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 114  Thyroid hormone signaling pathway 
 1 gene, 1 drug (DrugBank), 36 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 115  TNF signaling pathway 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 116  Toll-like receptor signaling pathway 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 117  Toxoplasmosis 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 118  Tuberculosis 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 119  Type I diabetes mellitus 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 120  Type II diabetes mellitus 
 2 genes, 2 drugs (DrugBank), 52 diseases shown 		  [1] MTOR   D00753   Sirolimus   [36] 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 
 [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 121  Vascular smooth muscle contraction 
 1 gene, 1 drug (DrugBank), 18 diseases shown 		  [1] AGTR1   D00357   Losartan   [18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 
 D08146 
 122  Viral protein interaction with cytokine and cytokine receptor 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 
 123  Yersinia infection 
 1 gene, 1 drug (DrugBank), 23 diseases shown 		  [1] TNF   D02598   Infliximab   [23] 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 

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