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 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

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35 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY * 
 On map, Yellow: Drug target, Red: Disease-related 		  KEGG GENES * 
 [Number of genes] 		  KEGG DRUG *   DrugBank   Disease ID * 
 [Number of diseases] 
 1  Arachidonic acid metabolism 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] PTGS2   D00969   Meloxicam   [4] 46, 49, 271, 296 
 2  Bile secretion 
 1 gene, 1 drug (DrugBank), 3 diseases shown 		  [1] NR1H4   D09360   Obeticholic acid   [3] 93, 265, 296 
 3  C-type lectin receptor signaling pathway 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] PTGS2   D00969   Meloxicam   [4] 46, 49, 271, 296 
 4  Calcium signaling pathway 
 5 genes, 1 drug (DrugBank), 1 disease shown 		  [5] CHRM1, CHRM2, CHRM3, CHRM5, CHRNA7   D00765   Rocuronium   [1] 296 
 5  cAMP signaling pathway 
 2 genes, 1 drug (DrugBank), 1 disease shown 		  [2] CHRM1, CHRM2   D00765   Rocuronium   [1] 296 
 6  Chemical carcinogenesis 
 2 genes, 2 drugs (DrugBank), 4 diseases shown 		  [1] CHRNA7   D00765   Rocuronium   [1] 296 
 [1] PTGS2   D00969   Meloxicam   [4] 46, 49, 271, 296 
 7  Cholinergic synapse 
 11 genes, 1 drug (DrugBank), 1 disease shown 		  [11] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, CHRNA3, CHRNA4, CHRNA6, CHRNA7, CHRNB2, CHRNB4   D00765   Rocuronium   [1] 296 
 8  GABAergic synapse 
 16 genes, 1 drug (DrugBank), 8 diseases shown 		  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00549   Propofol   [8] 6, 21, 22, 34, 46, 84, 98, 296 
 9  Gastric acid secretion 
 1 gene, 1 drug (DrugBank), 1 disease shown 		  [1] CHRM3   D00765   Rocuronium   [1] 296 
 10  Human cytomegalovirus infection 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] PTGS2   D00969   Meloxicam   [4] 46, 49, 271, 296 
 11  Human papillomavirus infection 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] PTGS2   D00969   Meloxicam   [4] 46, 49, 271, 296 
 12  IL-17 signaling pathway 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] PTGS2   D00969   Meloxicam   [4] 46, 49, 271, 296 
 13  Insulin secretion 
 1 gene, 1 drug (DrugBank), 1 disease shown 		  [1] CHRM3   D00765   Rocuronium   [1] 296 
 14  Kaposi sarcoma-associated herpesvirus infection 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] PTGS2   D00969   Meloxicam   [4] 46, 49, 271, 296 
 15  Leishmaniasis 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] PTGS2   D00969   Meloxicam   [4] 46, 49, 271, 296 
 16  Metabolic pathways 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] PTGS2   D00969   Meloxicam   [4] 46, 49, 271, 296 
 17  MicroRNAs in cancer 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] PTGS2   D00969   Meloxicam   [4] 46, 49, 271, 296 
 18  Morphine addiction 
 16 genes, 1 drug (DrugBank), 8 diseases shown 		  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00549   Propofol   [8] 6, 21, 22, 34, 46, 84, 98, 296 
 19  Neuroactive ligand-receptor interaction 
 33 genes, 5 drugs (DrugBank), 60 diseases shown 		  [16] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, CHRNA10, CHRNA2, CHRNA3, CHRNA4, CHRNA5, CHRNA6, CHRNA7, CHRNA9, CHRNB2, CHRNB3, CHRNB4   D00765   Rocuronium   [1] 296 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00549   Propofol   [8] 6, 21, 22, 34, 46, 84, 98, 296 
 [1] NR3C1   D00292   Dexamethasone   [20] 13, 16, 28, 35, 46, 53, 63, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 222, 296, 299 
 D00975 
 D01510 
 D01615 
 D01632 
 D01948 
 D02174 
 D02591 
 D02592 
 D00407   Methylprednisolone   [36] 2, 13, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 145, 164, 220, 222, 224, 271, 283, 284, 285, 296 
 D00751 
 D00979 
 D05000 
 D05001 
 D05002 
 D00472   Prednisolone   [38] 11, 13, 25, 26, 35, 38, 39, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 
 D00980 
 D00981 
 D00982 
 D01239 
 D01998 
 D02156 
 D03301 
 20  NF-kappa B signaling pathway 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] PTGS2   D00969   Meloxicam   [4] 46, 49, 271, 296 
 21  Nicotine addiction 
 20 genes, 2 drugs (DrugBank), 8 diseases shown 		  [4] CHRNA4, CHRNA6, CHRNA7, CHRNB2   D00765   Rocuronium   [1] 296 
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00549   Propofol   [8] 6, 21, 22, 34, 46, 84, 98, 296 
 22  Ovarian steroidogenesis 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] PTGS2   D00969   Meloxicam   [4] 46, 49, 271, 296 
 23  Oxytocin signaling pathway 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] PTGS2   D00969   Meloxicam   [4] 46, 49, 271, 296 
 24  Pancreatic secretion 
 1 gene, 1 drug (DrugBank), 1 disease shown 		  [1] CHRM3   D00765   Rocuronium   [1] 296 
 25  Pathways in cancer 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] PTGS2   D00969   Meloxicam   [4] 46, 49, 271, 296 
 26  PI3K-Akt signaling pathway 
 2 genes, 1 drug (DrugBank), 1 disease shown 		  [2] CHRM1, CHRM2   D00765   Rocuronium   [1] 296 
 27  Regulation of actin cytoskeleton 
 5 genes, 1 drug (DrugBank), 1 disease shown 		  [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5   D00765   Rocuronium   [1] 296 
 28  Regulation of lipolysis in adipocytes 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] PTGS2   D00969   Meloxicam   [4] 46, 49, 271, 296 
 29  Retrograde endocannabinoid signaling 
 17 genes, 2 drugs (DrugBank), 10 diseases shown 		  [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D00549   Propofol   [8] 6, 21, 22, 34, 46, 84, 98, 296 
 [1] PTGS2   D00969   Meloxicam   [4] 46, 49, 271, 296 
 30  Salivary secretion 
 1 gene, 1 drug (DrugBank), 1 disease shown 		  [1] CHRM3   D00765   Rocuronium   [1] 296 
 31  Serotonergic synapse 
 4 genes, 2 drugs (DrugBank), 10 diseases shown 		  [3] GABRB1, GABRB2, GABRB3   D00549   Propofol   [8] 6, 21, 22, 34, 46, 84, 98, 296 
 [1] PTGS2   D00969   Meloxicam   [4] 46, 49, 271, 296 
 32  Small cell lung cancer 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] PTGS2   D00969   Meloxicam   [4] 46, 49, 271, 296 
 33  Taste transduction 
 7 genes, 2 drugs (DrugBank), 8 diseases shown 		  [1] CHRM3   D00765   Rocuronium   [1] 296 
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6   D00549   Propofol   [8] 6, 21, 22, 34, 46, 84, 98, 296 
 34  TNF signaling pathway 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] PTGS2   D00969   Meloxicam   [4] 46, 49, 271, 296 
 35  VEGF signaling pathway 
 1 gene, 1 drug (DrugBank), 4 diseases shown 		  [1] PTGS2   D00969   Meloxicam   [4] 46, 49, 271, 296 

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