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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1(R)-[N-metil-11C1-PK11195(PK)----1件: 127 💬
218-F]DPA-714----1件: 127 💬
318F-AV-1451----3件: 5, 7, 127 💬
418F-AV-45----2件: 6, 127 💬
518F-FDG1件: Fludeoxyglucose (18F)---8件: 5, 6, 7, 13, 84, 85, 127, 300 💬
618F-RO6958948----3件: 5, 7, 127 💬
718F]DPA-714----2件: 13, 127 💬
8[18F]PI-2620----2件: 6, 127 💬
9AL----11件: 5, 6, 7, 13, 28, 51, 67, 86, 97, 114, 127 💬
10AL0011件: Latozinemab1件: Latozinemab 💬1件: SORT1 💬3件: Cholesterol metabolism, Lysosome, Neurotrophin signaling pathway 💬2件: 2, 127 💬
11AMANTADINE1件: Amantadine1件: Amantadine 💬5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬4件: 6, 8, 13, 127 💬
12Amiodarone1件: Amiodarone1件: Amiodarone 💬16件: ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
KCND3,
KCNJ11,
KCNJ12,
KCNJ3,
KCNJ5,
KCNJ8,
KCNQ1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		32件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy, Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Insulin secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 28, 127 💬
13Amyvid1件: Florbetapir (18F)---2件: 13, 127 💬
14AV1451 Tau----1件: 127 💬
15BIIB092----3件: 5, 7, 127 💬
16Blood sample----20件: 8, 13, 46, 49, 51, 53, 61, 66, 84, 88, 96, 97, 107, 127, 235, 274, 280, 288, 294, 299 💬
17C-11 PiB1件: Pittsburgh Compound B---1件: 127 💬
18Carbonate1件: Carbonate ion---12件: 2, 13, 17, 18, 19, 46, 53, 75, 96, 127, 235, 299 💬
19CENSAVUDINE1件: Censavudine1件: Censavudine 💬--2件: 2, 127 💬
20Chloride1件: Chloride ion---28件: 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 97, 107, 127, 168, 171, 193, 227, 228, 251, 288, 296, 297, 299, 338 💬
21Citalopram1件: Citalopram1件: Citalopram 💬1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬7件: 6, 8, 13, 18, 46, 98, 127 💬
22Davunetide1件: Davunetide1件: Davunetide 💬--3件: 5, 7, 127 💬
23Davunetide (AL-108, NAP)1件: Davunetide1件: Davunetide 💬--3件: 5, 7, 127 💬
24DNL593----1件: 127 💬
25DNL593 Sterile Lyophilisate----1件: 127 💬
26Donepezil1件: Donepezil1件: Donepezil 💬1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬9件: 5, 6, 13, 46, 78, 124, 127, 156, 206 💬
27DPA----5件: 2, 6, 13, 85, 127 💬
28ET-STEM----1件: 127 💬
29EVP-0334----1件: 127 💬
30F 18 T807----2件: 2, 127 💬
31F-18----2件: 5, 127 💬
32F-18 AV 1451----2件: 5, 127 💬
33F-18 FDG----1件: 127 💬
34Ferulic acid1件: Ferulic acid---1件: 127 💬
35Florbetapir (18F)----1件: 127 💬
36Florbetapir 18F----1件: 127 💬
37Florbetapir 18F Injection----1件: 127 💬
38Flortaucipir1件: Flortaucipir1件: Flortaucipir F 18 💬1件: MAPT 💬4件: Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬3件: 5, 7, 127 💬
39Flortaucipir F181件: Flortaucipir1件: Flortaucipir F 18 💬1件: MAPT 💬4件: Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬3件: 5, 7, 127 💬
40Flutemetamol1件: Flutemetamol---4件: 5, 6, 7, 127 💬
41FPI-2620----1件: 127 💬
42FRM-0334----1件: 127 💬
43GALANTAMINE1件: Galantamine1件: Galantamine 💬1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬2件: 6, 127 💬
44Galantamine hydrobromide1件: Galantamine1件: Galantamine 💬1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬2件: 6, 127 💬
45Histone Deacetylase Inhibitor----1件: 127 💬
46Intranasal oxytocin1件: Oxytocin1件: Oxytocin 💬1件: OXTR 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬2件: 127, 193 💬
47Latozinemab1件: Latozinemab1件: Latozinemab 💬1件: SORT1 💬3件: Cholesterol metabolism, Lysosome, Neurotrophin signaling pathway 💬1件: 127 💬
48Leuco-methylthioninium bis(hydromethanesulfonate)1件: Methylthioninium---1件: 127 💬
49LITHIUM CARBONATE3件: Carbonate ion,
Lithium carbonate,
Lithium citrate		2件: Lithium carbonate ,
Lithium citrate 💬		--5件: 2, 13, 17, 18, 127 💬
50LMTM1件: Hydromethylthionine mesylate1件: Hydromethylthionine mesylate 💬1件: MAPT 💬4件: Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬1件: 127 💬
51LMTM/TRx02371件: Hydromethylthionine mesylate1件: Hydromethylthionine mesylate 💬1件: MAPT 💬4件: Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬1件: 127 💬
52Lumbar puncture----4件: 13, 96, 97, 127 💬
53Memantine1件: Memantine1件: Memantine 💬5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
54MEMANTINE HYDROCHLORIDE1件: Memantine1件: Memantine 💬5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬3件: 2, 6, 127 💬
55Metformin1件: Metformin1件: Metformin 💬2件: PRKAA1,
PRKAA2 💬		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬25件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
56Methylthioninium1件: Methylthioninium---1件: 127 💬
57Methylthioninium chloride3件: Chloride ion,
Methylene blue,
Methylthioninium		2件: Methylene blue ,
Methylthioninium chloride hydrate 💬		--1件: 127 💬
58MTC TRx0014-001 capsules----1件: 127 💬
59N,N,N',N'-tetramethyl-10H-phenothiazine-3,7-diaminium bis(methanesulfonate)1件: Phenothiazine1件: Phenothiazine 💬--1件: 127 💬
60N,N,N?,N?-tetramethyl-10H-phenothiazine-3,7-diaminium bis(methanesulfonate)1件: Phenothiazine1件: Phenothiazine 💬--1件: 127 💬
61N,N,N’,N’-tetramethyl-10H-phenothiazine-3,7-diaminium bis(methanesulfonate)1件: Phenothiazine1件: Phenothiazine 💬--1件: 127 💬
62NABILONE1件: Nabilone1件: Nabilone 💬2件: CNR1,
CNR2 💬		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬3件: 6, 13, 127 💬
63Novolin-R insulin----1件: 127 💬
64Open label - AL0011件: Latozinemab1件: Latozinemab 💬1件: SORT1 💬3件: Cholesterol metabolism, Lysosome, Neurotrophin signaling pathway 💬1件: 127 💬
65Oxytocin1件: Oxytocin1件: Oxytocin 💬1件: OXTR 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬7件: 6, 72, 127, 168, 193, 206, 226 💬
66PBFT02----1件: 127 💬
67PEA-LUT----1件: 127 💬
68Phenothiazine1件: Phenothiazine1件: Phenothiazine 💬--1件: 127 💬
69Pittsburgh Compound B1件: Pittsburgh Compound B---1件: 127 💬
70Pittsburgh Compound B (C-11 PiB)1件: Pittsburgh Compound B---1件: 127 💬
71Saline Nasal Mist----1件: 127 💬
72Synthetic stereopure antisense oligonucleotide targeting human C9orf72 hexanucleotide repeat-containing mRNA transcripts----2件: 2, 127 💬
73Syntocinon1件: Oxytocin1件: Oxytocin 💬1件: OXTR 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬3件: 6, 127, 193 💬
74T807----1件: 127 💬
75Tau (18-F-AV-1451)----1件: 127 💬
76TOLCAPONE1件: Tolcapone1件: Tolcapone 💬1件: COMT 💬4件: Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬3件: 6, 28, 127 💬
77TPN-101----3件: 2, 127, 325 💬
78TPN-101, 400 mg/day----2件: 2, 127 💬
79TRX0237----1件: 127 💬
80Verdiperstat1件: Verdiperstat1件: Verdiperstat 💬1件: MPO 💬5件: Acute myeloid leukemia, Drug metabolism - other enzymes, Neutrophil extracellular trap formation, Phagosome, Transcriptional misregulation in cancer 💬3件: 2, 17, 127 💬
81Vizamyl1件: Flutemetamol (18F)---3件: 5, 7, 127 💬
82Vizamyl (flutemetamol(F-18))2件: Flutemetamol,
Flutemetamol (18F)		---3件: 5, 7, 127 💬
83WVE-004----2件: 2, 127 💬