1 | (4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-3-{[4’- | - | - | - | - | 1件: 79 79 💬 |
2 | 1,2-Dihexadecanoyl-sn-Glycero-3-Phospho-(1-raac-glycerol) | 1件: Glycerin Glycerin | 1件: Glycerin
Glycerin
💬 | - | - | 1件: 79 79 💬 |
3 | AAV directed hLDLR gene therapy | - | - | - | - | 1件: 79 79 💬 |
4 | AAV8.TBG.hLDLR | - | - | - | - | 1件: 79 79 💬 |
5 | Acetate | 1件: Acetate Acetate | - | - | - | 41件: 1 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299 💬 |
6 | AEGR-733 | - | - | - | - | 1件: 79 79 💬 |
7 | AK102 | - | - | - | - | 1件: 79 79 💬 |
8 | AKCEA-ANGPTL3-LRX | - | - | - | - | 2件: 79 79, 265 💬 |
9 | ALIROCUMAB | 1件: Alirocumab Alirocumab | 1件: Alirocumab
Alirocumab
💬 | 1件: PCSK9 PCSK9 💬 | 1件: Cholesterol metabolism Cholesterol metabolism 💬 | 1件: 79 79 💬 |
10 | Alirocumab SAR236553 (REGN727) | 1件: Alirocumab Alirocumab | 1件: Alirocumab
Alirocumab
💬 | 1件: PCSK9 PCSK9 💬 | 1件: Cholesterol metabolism Cholesterol metabolism 💬 | 1件: 79 79 💬 |
11 | ALN-60212 | - | - | - | - | 1件: 79 79 💬 |
12 | ALN-PCSSC | 1件: Inclisiran Inclisiran | 1件: Inclisiran
Inclisiran
💬 | 1件: PCSK9 PCSK9 💬 | 1件: Cholesterol metabolism Cholesterol metabolism 💬 | 1件: 79 79 💬 |
13 | AMG 145 | - | - | - | - | 1件: 79 79 💬 |
14 | AMG145 | - | - | - | - | 1件: 79 79 💬 |
15 | ANACETRAPIB | 1件: Anacetrapib Anacetrapib | 1件: Anacetrapib
Anacetrapib
💬 | 1件: CETP CETP 💬 | 1件: Cholesterol metabolism Cholesterol metabolism 💬 | 1件: 79 79 💬 |
16 | ARO-ANG 3 Injection | - | - | - | - | 1件: 79 79 💬 |
17 | Atorvastatin | 1件: Atorvastatin Atorvastatin | 1件: Atorvastatin
Atorvastatin
💬 | 1件: HMGCR HMGCR 💬 | 4件: AMPK signaling pathway AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬 | 19件: 13 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 |
18 | Calcium | 2件: Calcium Calcium, Calcium carbonate | 2件: Calcium carbonate
Calcium carbonate
,
Calcium carbonate
💬 | - | - | 27件: 6 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299 💬 |
19 | Calcium rosuvastatin | 2件: Calcium Calcium, Rosuvastatin | 1件: Rosuvastatin
Rosuvastatin
💬 | 1件: HMGCR HMGCR 💬 | 4件: AMPK signaling pathway AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬 | 1件: 79 79 💬 |
20 | CER-001 | - | - | - | - | 1件: 79 79 💬 |
21 | Cholestyramine | 1件: Cholestyramine Cholestyramine | - | - | - | 2件: 13 13, 79 💬 |
22 | Comparator: ezetimibe | 1件: Ezetimibe Ezetimibe | 1件: Ezetimibe
Ezetimibe
💬 | 1件: NPC1L1 NPC1L1 💬 | 1件: Fat digestion and absorption Fat digestion and absorption 💬 | 2件: 79 79, 260 💬 |
23 | Crestor | 1件: Rosuvastatin Rosuvastatin | 1件: Rosuvastatin
Rosuvastatin
💬 | 1件: HMGCR HMGCR 💬 | 4件: AMPK signaling pathway AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬 | 3件: 49 49, 79, 299 💬 |
24 | Crestor Film-Coated Tablet | 1件: Rosuvastatin Rosuvastatin | 1件: Rosuvastatin
Rosuvastatin
💬 | 1件: HMGCR HMGCR 💬 | 4件: AMPK signaling pathway AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬 | 1件: 79 79 💬 |
25 | Crestor Tablets (calcium rosuvastatin) Film-Coated tablets | 2件: Calcium Calcium, Rosuvastatin | 1件: Rosuvastatin
Rosuvastatin
💬 | 1件: HMGCR HMGCR 💬 | 4件: AMPK signaling pathway AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬 | 1件: 79 79 💬 |
26 | Current lipid-lowering treatment | - | - | - | - | 1件: 79 79 💬 |
27 | DPPG | - | - | - | - | 1件: 79 79 💬 |
28 | EVINACUMAB | 1件: Evinacumab Evinacumab | 1件: Evinacumab
Evinacumab
💬 | 1件: ANGPTL3 ANGPTL3 💬 | 1件: Cholesterol metabolism Cholesterol metabolism 💬 | 1件: 79 79 💬 |
29 | Evinacumab (REGN1500) | 1件: Evinacumab Evinacumab | 1件: Evinacumab
Evinacumab
💬 | 1件: ANGPTL3 ANGPTL3 💬 | 1件: Cholesterol metabolism Cholesterol metabolism 💬 | 1件: 79 79 💬 |
30 | EVOLOCUMAB | 1件: Evolocumab Evolocumab | 1件: Evolocumab
Evolocumab
💬 | 1件: PCSK9 PCSK9 💬 | 1件: Cholesterol metabolism Cholesterol metabolism 💬 | 2件: 79 79, 222 💬 |
31 | Evolocumab (AMG 145) | 1件: Evolocumab Evolocumab | 1件: Evolocumab
Evolocumab
💬 | 1件: PCSK9 PCSK9 💬 | 1件: Cholesterol metabolism Cholesterol metabolism 💬 | 1件: 79 79 💬 |
32 | Ezetimibe | 1件: Ezetimibe Ezetimibe | 1件: Ezetimibe
Ezetimibe
💬 | 1件: NPC1L1 NPC1L1 💬 | 1件: Fat digestion and absorption Fat digestion and absorption 💬 | 4件: 49 49, 79, 93, 260 💬 |
33 | Fenofibrate | 1件: Fenofibrate Fenofibrate | 1件: Fenofibrate
Fenofibrate
💬 | 1件: PPARA PPARA 💬 | 10件: Adipocytokine signaling pathway Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬 | 6件: 8 8, 79, 93, 94, 97, 265 💬 |
34 | Fluvastatin | 1件: Fluvastatin Fluvastatin | 1件: Fluvastatin
Fluvastatin
💬 | 1件: HMGCR HMGCR 💬 | 4件: AMPK signaling pathway AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬 | 3件: 79 79, 218, 222 💬 |
35 | Gemcabene | 1件: Gemcabene Gemcabene | - | - | - | 2件: 79 79, 265 💬 |
36 | Gene analysis | - | - | - | - | 1件: 79 79 💬 |
37 | Glycerol | 1件: Glycerin Glycerin | 1件: Glycerin
Glycerin
💬 | - | - | 5件: 6 6, 13, 79, 316, 317 💬 |
38 | IBI306 | - | - | - | - | 1件: 79 79 💬 |
39 | Implitapide | 1件: Implitapide Implitapide | - | - | - | 1件: 79 79 💬 |
40 | Inclisiran | 1件: Inclisiran Inclisiran | 1件: Inclisiran
Inclisiran
💬 | 1件: PCSK9 PCSK9 💬 | 1件: Cholesterol metabolism Cholesterol metabolism 💬 | 1件: 79 79 💬 |
41 | Inclisiran Sodium | 1件: Inclisiran Inclisiran | 1件: Inclisiran
Inclisiran
💬 | 1件: PCSK9 PCSK9 💬 | 1件: Cholesterol metabolism Cholesterol metabolism 💬 | 1件: 79 79 💬 |
42 | Inclisiran Sodium for injection | 1件: Inclisiran Inclisiran | 1件: Inclisiran
Inclisiran
💬 | 1件: PCSK9 PCSK9 💬 | 1件: Cholesterol metabolism Cholesterol metabolism 💬 | 1件: 79 79 💬 |
43 | ISIS 301012 | - | - | - | - | 1件: 79 79 💬 |
44 | ISIS 301012 phosphorothioate oligonucleotide | - | - | - | - | 1件: 79 79 💬 |
45 | ISIS 703802 | - | - | - | - | 1件: 79 79 💬 |
46 | JS002 | - | - | - | - | 1件: 79 79 💬 |
47 | KJX839 | - | - | - | - | 1件: 79 79 💬 |
48 | Lapaquistat | 1件: Lapaquistat Lapaquistat | - | - | - | 1件: 79 79 💬 |
49 | Lapaquistat acetate and current lipid-lowering treatment | 2件: Acetate Acetate, Lapaquistat | - | - | - | 1件: 79 79 💬 |
50 | Leqvio | 1件: Inclisiran Inclisiran | 1件: Inclisiran
Inclisiran
💬 | 1件: PCSK9 PCSK9 💬 | 1件: Cholesterol metabolism Cholesterol metabolism 💬 | 1件: 79 79 💬 |
51 | Leqvio 284 mg solution for injection in pre-filled syringe | 1件: Inclisiran Inclisiran | 1件: Inclisiran
Inclisiran
💬 | 1件: PCSK9 PCSK9 💬 | 1件: Cholesterol metabolism Cholesterol metabolism 💬 | 1件: 79 79 💬 |
52 | Lerodalcibep | - | - | - | - | 1件: 79 79 💬 |
53 | LIB003 | - | - | - | - | 1件: 79 79 💬 |
54 | Lojuxta | 1件: Lomitapide Lomitapide | 1件: Lomitapide
Lomitapide
💬 | 1件: MTTP MTTP 💬 | 1件: Fat digestion and absorption Fat digestion and absorption 💬 | 1件: 79 79 💬 |
55 | Lojuxta 10 mg hard capsules | 1件: Lomitapide Lomitapide | 1件: Lomitapide
Lomitapide
💬 | 1件: MTTP MTTP 💬 | 1件: Fat digestion and absorption Fat digestion and absorption 💬 | 1件: 79 79 💬 |
56 | Lojuxta 20 mg hard capsules | 1件: Lomitapide Lomitapide | 1件: Lomitapide
Lomitapide
💬 | 1件: MTTP MTTP 💬 | 1件: Fat digestion and absorption Fat digestion and absorption 💬 | 1件: 79 79 💬 |
57 | Lojuxta 5 mg hard capsules | 1件: Lomitapide Lomitapide | 1件: Lomitapide
Lomitapide
💬 | 1件: MTTP MTTP 💬 | 1件: Fat digestion and absorption Fat digestion and absorption 💬 | 1件: 79 79 💬 |
58 | LOMITAPIDE | 1件: Lomitapide Lomitapide | 1件: Lomitapide
Lomitapide
💬 | 1件: MTTP MTTP 💬 | 1件: Fat digestion and absorption Fat digestion and absorption 💬 | 1件: 79 79 💬 |
59 | Lomitapide 2mg hard capsules | 1件: Lomitapide Lomitapide | 1件: Lomitapide
Lomitapide
💬 | 1件: MTTP MTTP 💬 | 1件: Fat digestion and absorption Fat digestion and absorption 💬 | 1件: 79 79 💬 |
60 | Lovastatin | 1件: Lovastatin Lovastatin | 1件: Lovastatin
Lovastatin
💬 | 1件: HMGCR HMGCR 💬 | 4件: AMPK signaling pathway AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬 | 11件: 6 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 |
61 | MBX-8025 | - | - | - | - | 3件: 79 79, 93, 94 💬 |
62 | MBX-8025 50 mg (Dose Escalation Period 1) | - | - | - | - | 1件: 79 79 💬 |
63 | MBX-8025 50 mg or 100 mg (Dose Escalation Period 2) | - | - | - | - | 1件: 79 79 💬 |
64 | MBX-8025 50 mg, 100 mg or 200 mg (Dose Escalation Period 3) | - | - | - | - | 1件: 79 79 💬 |
65 | Mipomersen | 1件: Mipomersen Mipomersen | - | - | - | 1件: 79 79 💬 |
66 | MK-0859 | - | - | - | - | 1件: 79 79 💬 |
67 | Nicotinic acid | 1件: Niacin Niacin | 1件: Niacin
Niacin
💬 | - | - | 1件: 79 79 💬 |
68 | Omega-3 | 1件: Omega-3 fatty acids Omega-3 fatty acids | - | - | - | 7件: 13 13, 46, 49, 66, 79, 96, 299 💬 |
69 | Omega-3 fatty acids | 1件: Omega-3 fatty acids Omega-3 fatty acids | - | - | - | 2件: 13 13, 79 💬 |
70 | Phospholipids | 1件: Omega-3 fatty acids Omega-3 fatty acids | - | - | - | 1件: 79 79 💬 |
71 | Placebo | - | - | - | - | 28件: 3 3, 5, 6, 11, 13, 14, 37, 40, 46, 49, 50, 51, 53, 63, 66, 67, 79, 85, 86, 88, 96, 97, 140, 144, 149, 226, 271, 276 💬 |
72 | Praluent | 1件: Alirocumab Alirocumab | 1件: Alirocumab
Alirocumab
💬 | 1件: PCSK9 PCSK9 💬 | 1件: Cholesterol metabolism Cholesterol metabolism 💬 | 1件: 79 79 💬 |
73 | Pravastatin | 1件: Pravastatin Pravastatin | 1件: Pravastatin
Pravastatin
💬 | 1件: HMGCR HMGCR 💬 | 4件: AMPK signaling pathway AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬 | 9件: 13 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
74 | PRD7255830 | - | - | - | - | 1件: 79 79 💬 |
75 | PRD7255977 | - | - | - | - | 1件: 79 79 💬 |
76 | PRD7256003 | - | - | - | - | 1件: 79 79 💬 |
77 | Prednisone | 1件: Prednisone Prednisone | 1件: Prednisone
Prednisone
💬 | 1件: NR3C1 NR3C1 💬 | 1件: Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | 45件: 2 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬 |
78 | R727 | - | - | - | - | 1件: 79 79 💬 |
79 | Recombinant Human Apolipoprotein | - | - | - | - | 1件: 79 79 💬 |
80 | Recombinant Human Apolipoprotein A-I | - | - | - | - | 1件: 79 79 💬 |
81 | Recombinant Human Apolipoprotein A-I/Phospholipids Complex | 1件: Omega-3 fatty acids Omega-3 fatty acids | - | - | - | 1件: 79 79 💬 |
82 | Recombinant human apolipoprotein a1 | - | - | - | - | 1件: 79 79 💬 |
83 | REGN1500 | - | - | - | - | 1件: 79 79 💬 |
84 | REGN1500 250 mg SC/15 mg/kg IV/450 mg SC | - | - | - | - | 1件: 79 79 💬 |
85 | REGN7272 | - | - | - | - | 1件: 79 79 💬 |
86 | Repatha | 1件: Evolocumab Evolocumab | 1件: Evolocumab
Evolocumab
💬 | 1件: PCSK9 PCSK9 💬 | 1件: Cholesterol metabolism Cholesterol metabolism 💬 | 1件: 79 79 💬 |
87 | Repatha (evolocumab) | 1件: Evolocumab Evolocumab | 1件: Evolocumab
Evolocumab
💬 | 1件: PCSK9 PCSK9 💬 | 1件: Cholesterol metabolism Cholesterol metabolism 💬 | 1件: 79 79 💬 |
88 | Repatha 140 mg Solution for Injection in Pre-filled Pen | 1件: Evolocumab Evolocumab | 1件: Evolocumab
Evolocumab
💬 | 1件: PCSK9 PCSK9 💬 | 1件: Cholesterol metabolism Cholesterol metabolism 💬 | 1件: 79 79 💬 |
89 | Repatha 140 mg soluzione per iniezione in penna preriempita. | 1件: Evolocumab Evolocumab | 1件: Evolocumab
Evolocumab
💬 | 1件: PCSK9 PCSK9 💬 | 1件: Cholesterol metabolism Cholesterol metabolism 💬 | 1件: 79 79 💬 |
90 | Repatha 420 mg solution for injection in cartridge | 1件: Evolocumab Evolocumab | 1件: Evolocumab
Evolocumab
💬 | 1件: PCSK9 PCSK9 💬 | 1件: Cholesterol metabolism Cholesterol metabolism 💬 | 1件: 79 79 💬 |
91 | Repatha 420 mg soluzione per iniezione in cartuccia | 1件: Evolocumab Evolocumab | 1件: Evolocumab
Evolocumab
💬 | 1件: PCSK9 PCSK9 💬 | 1件: Cholesterol metabolism Cholesterol metabolism 💬 | 1件: 79 79 💬 |
92 | Rosuvastatin | 1件: Rosuvastatin Rosuvastatin | 1件: Rosuvastatin
Rosuvastatin
💬 | 1件: HMGCR HMGCR 💬 | 4件: AMPK signaling pathway AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬 | 11件: 6 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬 |
93 | Rosuvastatin 20mg | 1件: Rosuvastatin Rosuvastatin | 1件: Rosuvastatin
Rosuvastatin
💬 | 1件: HMGCR HMGCR 💬 | 4件: AMPK signaling pathway AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬 | 1件: 79 79 💬 |
94 | ROSUVASTATIN CALCIUM | 2件: Calcium Calcium, Rosuvastatin | 1件: Rosuvastatin
Rosuvastatin
💬 | 1件: HMGCR HMGCR 💬 | 4件: AMPK signaling pathway AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬 | 4件: 49 49, 79, 97, 299 💬 |
95 | SAR236553 | - | - | - | - | 1件: 79 79 💬 |
96 | Sfingomielina | - | - | - | - | 1件: 79 79 💬 |
97 | SHR-1209 | - | - | - | - | 1件: 79 79 💬 |
98 | Simvastatin | 1件: Simvastatin Simvastatin | 1件: Simvastatin
Simvastatin
💬 | 1件: HMGCR HMGCR 💬 | 4件: AMPK signaling pathway AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬 | 21件: 6 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
99 | Single intravenous (IV) dose of human Low Density Lipoprotein Receptor (LDLR) Gene Therapy | - | - | - | - | 1件: 79 79 💬 |
100 | Sphingomyelin | - | - | - | - | 1件: 79 79 💬 |
101 | Standard of Care | - | - | - | - | 8件: 6 6, 13, 49, 51, 63, 64, 79, 171 💬 |
102 | Statins | - | - | - | - | 2件: 46 46, 79 💬 |
103 | TAK-475 | 1件: TAK-475 TAK-475 | - | - | - | 1件: 79 79 💬 |
104 | Whole genome sequencing | - | - | - | - | 3件: 6 6, 79, 172 💬 |
105 | ZD4522 | - | - | - | - | 1件: 79 79 💬 |