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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
111C-CSar----2件: 93, 94 💬
23108006977----1件: 94 💬
3[18F]FP-R01-MG-F2----2件: 85, 94 💬
4A3907----1件: 94 💬
5Acetylcysteine1件: Acetylcysteine1件: Acetylcysteine 💬--21件: 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337 💬
6ACIDO DEOSSICOLICO----1件: 94 💬
7Acido Obeticolico----2件: 93, 94 💬
8All-trans retinoic acid1件: Tretinoin1件: Tretinoin 💬3件: PML,
RARA,
RARB 💬		12件: Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬1件: 94 💬
9ATRA1件: Tretinoin1件: Tretinoin 💬3件: PML,
RARA,
RARB 💬		12件: Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬2件: 63, 94 💬
10Azathioprine1件: Azathioprine1件: Azathioprine 💬--21件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162 💬
11AZT----2件: 94, 265 💬
12Befizal----1件: 94 💬
13BEFIZAL L.P. 400 mg, comprimé enrobé à libération prolongée----1件: 94 💬
14Bexotegrast----1件: 94 💬
15Bezafibrate1件: Bezafibrate1件: Bezafibrate 💬1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬7件: 20, 93, 94, 160, 296, 316, 324 💬
16Bezafibrate (400mg) in addition to standard 15-20 mg/kg/jour UDCA therapy2件: Bezafibrate,
Ursodeoxycholic acid		2件: Ursodiol ,
Bezafibrate 💬		2件: NR1H4,
PPARA 💬		11件: Adipocytokine signaling pathway, Alcoholic liver disease, Bile secretion, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬1件: 94 💬
17Bezalip----3件: 93, 94, 160 💬
18BTT1023----1件: 94 💬
19BTT1023 IV Infusion 20 mg/mL, 5 mL Drug Product----1件: 94 💬
20BUDESONIDE1件: Budesonide1件: Budesonide 💬1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬9件: 66, 93, 94, 95, 96, 97, 98, 228, 299 💬
21C10AB02----1件: 94 💬
22Calcium2件: Calcium,
Calcium carbonate		2件: Calcium carbonate ,
Calcium carbonate 💬		--27件: 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299 💬
23Cenicriviroc1件: Cenicriviroc1件: Cenicriviroc 💬2件: CCR2,
CCR5 💬		11件: Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Toxoplasmosis, Viral carcinogenesis, Viral life cycle - HIV-1, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus 💬1件: 94 💬
24Cenicriviroc 150 mg1件: Cenicriviroc1件: Cenicriviroc 💬2件: CCR2,
CCR5 💬		11件: Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Toxoplasmosis, Viral carcinogenesis, Viral life cycle - HIV-1, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus 💬1件: 94 💬
25CILO----1件: 94 💬
26Cilofexor1件: Cilofexor---2件: 93, 94 💬
27Cis-4-Hydroxy-L-Proline1件: Proline1件: Proline 💬--1件: 94 💬
28CLADRIBINE1件: Cladribine1件: Cladribine 💬1件: RRM1 💬6件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬3件: 11, 13, 94 💬
29CM-101----1件: 94 💬
30CS0159----2件: 93, 94 💬
31Curcumin1件: Curcumin---10件: 2, 13, 46, 67, 74, 94, 96, 97, 139, 299 💬
32DHA----8件: 6, 46, 48, 49, 94, 113, 299, 301 💬
33Docosahexaenoic acid1件: Doconexent---7件: 6, 49, 90, 94, 240, 299, 301 💬
34Docosahexaenoic Acid (DHA)1件: Doconexent---3件: 6, 94, 299 💬
35DUR-928----1件: 94 💬
36ELAFIBRANOR1件: Elafibranor1件: Elafibranor 💬1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬2件: 93, 94 💬
37Elafibranor 120 mg1件: Elafibranor1件: Elafibranor 💬1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬2件: 93, 94 💬
38Elafibranor 80 mg1件: Elafibranor1件: Elafibranor 💬1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬2件: 93, 94 💬
39Engineered recombinant human FGF19----1件: 94 💬
40Entyvio1件: Vedolizumab1件: Vedolizumab 💬2件: ITGA4,
ITGB7 💬		15件: Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Transcriptional misregulation in cancer, Yersinia infection 💬3件: 94, 96, 97 💬
41EP547----2件: 93, 94 💬
42Erlotinib1件: Erlotinib1件: Erlotinib 💬1件: EGFR 💬48件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis 💬1件: 94 💬
43Erlotinib (Tarceva)1件: Erlotinib1件: Erlotinib 💬1件: EGFR 💬48件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis 💬1件: 94 💬
44Fecal microbiota transplantation----5件: 2, 66, 94, 96, 97 💬
45Fenofibrate1件: Fenofibrate1件: Fenofibrate 💬1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬6件: 8, 79, 93, 94, 97, 265 💬
46Fluimucil----4件: 85, 94, 193, 298 💬
47FLUIMUCIL*20CPR EFF 600MG----2件: 94, 298 💬
48Genetic analysis----6件: 34, 85, 90, 93, 94, 96 💬
49GFT505----2件: 93, 94 💬
50Gluten-free diet----1件: 94 💬
51GS-66241件: Simtuzumab---2件: 85, 94 💬
52GS-9674----2件: 93, 94 💬
53HTD1801----1件: 94 💬
54Humanised IgG1 monoclonal antibody against human eotaxin-2----1件: 94 💬
55Hymecromone1件: Hymecromone1件: Hymecromone 💬--1件: 94 💬
56ICG----2件: 93, 94 💬
57INT-747, OCA----2件: 93, 94 💬
58IPN60190----1件: 94 💬
59LUM001----4件: 93, 94, 297, 338 💬
60MBX-8025----3件: 79, 93, 94 💬
61METRONIDAZOLE1件: Metronidazole1件: Metronidazole 💬--7件: 46, 51, 63, 94, 96, 97, 291 💬
62Minocycline1件: Minocycline1件: Minocycline 💬--13件: 2, 6, 8, 13, 46, 85, 90, 94, 162, 201, 206, 280, 299 💬
63Mitomycin1件: Mitomycin1件: Mitomycin 💬--2件: 94, 329 💬
64Mitomycin C1件: Mitomycin1件: Mitomycin 💬--1件: 94 💬
65Mizoribine1件: Mizoribine1件: Mizoribine 💬2件: IMPDH1,
IMPDH2 💬		4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬8件: 46, 49, 51, 53, 66, 94, 222, 224 💬
66MLN0002----3件: 94, 96, 97 💬
67NGM282----2件: 93, 94 💬
68Normal Saline----18件: 6, 13, 17, 22, 36, 46, 49, 60, 70, 94, 96, 210, 211, 226, 271, 276, 296, 299 💬
69Norucholic acid1件: norUrsodeoxycholic acid---2件: 93, 94 💬
70NorUDCA----1件: 94 💬
71NorUDCA (Norursodeoxycholic acid)1件: norUrsodeoxycholic acid---1件: 94 💬
72NorUrsodeoxycholic Acid1件: norUrsodeoxycholic acid---1件: 94 💬
73Norursodeoxycholic acid, NCA1件: norUrsodeoxycholic acid---1件: 94 💬
74OCA----2件: 94, 296 💬
75OCA 1,5 mg----1件: 94 💬
76OCA 5 mg----1件: 94 💬
77Oral all-trans retinoic acid (ATRA)1件: Tretinoin1件: Tretinoin 💬3件: PML,
RARA,
RARB 💬		12件: Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬1件: 94 💬
78Oral Vancomycin1件: Vancomycin1件: Vancomycin 💬--2件: 94, 296 💬
79Orbcel-C1件: Allogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells---2件: 94, 95 💬
80PHENYLBUTYRATE1件: Phenylbutyric acid---12件: 2, 3, 6, 8, 15, 93, 94, 244, 251, 297, 299, 338 💬
81PLN-748091件: PLN-74809---2件: 85, 94 💬
82Potassium1件: Potassium1件: Potassium 💬--13件: 36, 46, 66, 67, 88, 93, 94, 98, 115, 167, 179, 215, 235 💬
83Probiotics----5件: 6, 94, 96, 97, 291 💬
84Proline1件: Proline1件: Proline 💬--2件: 94, 97 💬
85Rec-h-FGF19----1件: 94 💬
86Retinoic acid1件: Tretinoin1件: Tretinoin 💬3件: PML,
RARA,
RARB 💬		12件: Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬2件: 94, 231 💬
87RITUXIMAB1件: Rituximab1件: Rituximab 💬1件: MS4A1 💬1件: Hematopoietic cell lineage 💬48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
88SELADELPAR1件: Seladelpar1件: Seladelpar 💬1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬2件: 93, 94 💬
89Simtuzimab----1件: 94 💬
90Simtuzumab1件: Simtuzumab---2件: 85, 94 💬
91Simvastatin1件: Simvastatin1件: Simvastatin 💬1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
92Simvastatin 40mg1件: Simvastatin1件: Simvastatin 💬1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬1件: 94 💬
93SULFASALAZINE1件: Sulfasalazine1件: Sulfasalazine 💬--6件: 46, 86, 94, 107, 270, 271 💬
94TBC----3件: 85, 94, 96 💬
95Thalidomide1件: Thalidomide1件: Thalidomide 💬1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬20件: 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
96UCMSC----2件: 51, 94 💬
97UDCA1件: Ursodeoxycholic acid1件: Ursodiol 💬1件: NR1H4 💬1件: Bile secretion 💬6件: 46, 67, 93, 94, 97, 296 💬
98Ursodeoxycholic acid1件: Ursodeoxycholic acid1件: Ursodiol 💬1件: NR1H4 💬1件: Bile secretion 💬10件: 6, 46, 67, 84, 93, 94, 95, 96, 97, 296 💬
99Ursodeoxycholic acid (UDCA)1件: Ursodeoxycholic acid1件: Ursodiol 💬1件: NR1H4 💬1件: Bile secretion 💬1件: 94 💬
100Ursofalk1件: Ursodeoxycholic acid1件: Ursodiol 💬1件: NR1H4 💬1件: Bile secretion 💬4件: 93, 94, 96, 97 💬
101Ursolic acid1件: Ursolic acid---1件: 94 💬
102Vancomycin1件: Vancomycin1件: Vancomycin 💬--8件: 13, 46, 70, 94, 96, 97, 296, 299 💬
103VEDOLIZUMAB1件: Vedolizumab1件: Vedolizumab 💬2件: ITGA4,
ITGB7 💬		15件: Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Transcriptional misregulation in cancer, Yersinia infection 💬3件: 94, 96, 97 💬
104Vedolizumab IV1件: Vedolizumab1件: Vedolizumab 💬2件: ITGA4,
ITGB7 💬		15件: Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Transcriptional misregulation in cancer, Yersinia infection 💬3件: 94, 96, 97 💬
105Vidofludimus1件: Vidofludimus---5件: 13, 46, 94, 96, 97 💬
106VIDOFLUDIMUS CALCIUM2件: Calcium,
Vidofludimus		---4件: 13, 94, 96, 97 💬
107Volixibat1件: Volixibat1件: Volixibat 💬--2件: 93, 94 💬
108Volixibat (formely SHP626, LUM002 or SAR548304B)1件: Volixibat1件: Volixibat 💬--1件: 94 💬
109Volixibat potassium2件: Potassium,
Volixibat		2件: Potassium ,
Volixibat 💬		--2件: 93, 94 💬
110Xifaxan1件: Rifaximin1件: Rifaximin 💬--2件: 65, 94 💬