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薬物名（臨床試験情報から抽出）
DrugBank
KEGG DRUG
KEGG GENES
KEGG PATHWAY
指定難病告示番号
1
BMS Drug-drug interaction cocktail (montelukast, flurbiprofen, omeprazole, midazolam, and
digoxin
)
5件:
Digoxin
Digoxin
,
Flurbiprofen
,
Midazolam
,
Montelukast
,
Omeprazole
5件:
Digoxin
Digoxin
,
Flurbiprofen
,
Omeprazole
,
Midazolam
,
Montelukast
💬
1. BMS Drug-drug interaction cocktail (montelukast, flurbiprofen, omeprazole, midazolam, and
digoxin
)
×
Name
Other Names
Digoxin
Digoxin (JP18/USP)
Lanoxicaps (TN)
Lanoxin (TN)
DIGOX
ジゴキシン
ジゴシン
Flurbiprofen
Flurbiprofen (JP18/USP/INN)
Ansaid (TN)
フルルビプロフェン
アドフィード
ゼポラス
フルルバン
フロベン
ヤクバン
Omeprazole
Omeprazole (JP18/USP/INN)
Prilosec (TN)
オメプラゾール
オメプラゾン
オメプラール
Midazolam
Midazolam (JAN/USP/INN)
Dormicum (TN)
Buccolam (TN)
Nayzilam (TN)
N/A
ミダゾラム
ドルミカム
ブコラム
ミダフレッサ
Montelukast
Montelukast (INN)
Brondilat (TN)
モンテルカスト
25件:
ATP1A1
ATP1A1
,
ATP1A2
,
ATP1A3
,
ATP1A4
,
ATP4A
,
ATP4B
,
CYSLTR1
,
GABRA1
,
GABRA2
,
GABRA3
,
GABRA4
,
GABRA5
,
GABRA6
,
GABRB1
,
GABRB2
,
GABRB3
,
GABRD
,
GABRE
,
GABRG1
,
GABRG2
,
GABRG3
,
GABRP
,
GABRQ
,
PTGS1
,
PTGS2
💬
25件:
ATP1A1
,
ATP1A2
,
ATP1A3
,
ATP1A4
,
ATP4A
,
ATP4B
,
CYSLTR1
,
GABRA1
,
GABRA2
,
GABRA3
,
GABRA4
,
GABRA5
,
GABRA6
,
GABRB
...
1. BMS Drug-drug interaction cocktail (montelukast, flurbiprofen, omeprazole, midazolam, and
digoxin
)
×
Name
Full Name
ATP1A1
ATPase Na+/K+ transporting subunit alpha 1
ATP1A2
ATPase Na+/K+ transporting subunit alpha 2
ATP1A3
ATPase Na+/K+ transporting subunit alpha 3
ATP1A4
ATPase Na+/K+ transporting subunit alpha 4
ATP4A
ATPase H+/K+ transporting subunit alpha
ATP4B
ATPase H+/K+ transporting subunit beta
CYSLTR1
cysteinyl leukotriene receptor 1
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
GABRA2
gamma-aminobutyric acid type A receptor subunit alpha2
GABRA3
gamma-aminobutyric acid type A receptor subunit alpha3
GABRA4
gamma-aminobutyric acid type A receptor subunit alpha4
GABRA5
gamma-aminobutyric acid type A receptor subunit alpha5
GABRA6
gamma-aminobutyric acid type A receptor subunit alpha6
GABRB1
gamma-aminobutyric acid type A receptor subunit beta1
GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
GABRB3
gamma-aminobutyric acid type A receptor subunit beta3
GABRD
gamma-aminobutyric acid type A receptor subunit delta
GABRE
gamma-aminobutyric acid type A receptor subunit epsilon
GABRG1
gamma-aminobutyric acid type A receptor subunit gamma1
GABRG2
gamma-aminobutyric acid type A receptor subunit gamma2
GABRG3
gamma-aminobutyric acid type A receptor subunit gamma3
GABRP
gamma-aminobutyric acid type A receptor subunit pi
GABRQ
gamma-aminobutyric acid type A receptor subunit theta
PTGS1
prostaglandin-endoperoxide synthase 1
PTGS2
prostaglandin-endoperoxide synthase 2
49件:
Adrenergic signaling in cardiomyocytes
Adrenergic signaling in cardiomyocytes
,
Aldosterone synthesis and secretion
,
Aldosterone-regulated sodium reabsorption
,
Alzheimer disease
,
Arachidonic acid metabolism
,
Bile secretion
,
C-type lectin receptor signaling pathway
,
Calcium signaling pathway
,
Carbohydrate digestion and absorption
,
Cardiac muscle contraction
,
Chemical carcinogenesis - DNA adducts
,
Collecting duct acid secretion
,
Endocrine and other factor-regulated calcium reabsorption
,
GABAergic synapse
,
Gastric acid secretion
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
IL-17 signaling pathway
,
Insulin secretion
,
Kaposi sarcoma-associated herpesvirus infection
,
Leishmaniasis
,
Metabolic pathways
,
MicroRNAs in cancer
,
Mineral absorption
,
Morphine addiction
,
NF-kappa B signaling pathway
,
Neuroactive ligand-receptor interaction
,
Nicotine addiction
,
Ovarian steroidogenesis
,
Oxidative phosphorylation
,
Oxytocin signaling pathway
,
Pancreatic secretion
,
Pathways in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Platelet activation
,
Protein digestion and absorption
,
Proximal tubule bicarbonate reclamation
,
Regulation of lipolysis in adipocytes
,
Retrograde endocannabinoid signaling
,
Salivary secretion
,
Serotonergic synapse
,
Small cell lung cancer
,
TNF signaling pathway
,
Taste transduction
,
Thyroid hormone signaling pathway
,
Thyroid hormone synthesis
,
VEGF signaling pathway
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
49件:
Adrenergic signaling in cardiomyocytes
,
Aldosterone synthesis and secretion
,
Aldosterone-regula
...
1件:
46
46
💬
1. BMS Drug-drug interaction cocktail (montelukast, flurbiprofen, omeprazole, midazolam, and
digoxin
)
×
告示番号
日本語名
英語名
46
悪性関節リウマチ
Malignant rheumatoid arthritis
2
Digoxin
1件:
Digoxin
Digoxin
1件:
Digoxin
Digoxin
💬
2.
Digoxin
×
Name
Other Names
Digoxin
Digoxin (JP18/USP)
Lanoxicaps (TN)
Lanoxin (TN)
DIGOX
ジゴキシン
ジゴシン
4件:
ATP1A1
ATP1A1
,
ATP1A2
,
ATP1A3
,
ATP1A4
💬
2.
Digoxin
×
Name
Full Name
ATP1A1
ATPase Na+/K+ transporting subunit alpha 1
ATP1A2
ATPase Na+/K+ transporting subunit alpha 2
ATP1A3
ATPase Na+/K+ transporting subunit alpha 3
ATP1A4
ATPase Na+/K+ transporting subunit alpha 4
18件:
Adrenergic signaling in cardiomyocytes
Adrenergic signaling in cardiomyocytes
,
Aldosterone synthesis and secretion
,
Aldosterone-regulated sodium reabsorption
,
Bile secretion
,
Carbohydrate digestion and absorption
,
Cardiac muscle contraction
,
Endocrine and other factor-regulated calcium reabsorption
,
Gastric acid secretion
,
Insulin secretion
,
Mineral absorption
,
Pancreatic secretion
,
Protein digestion and absorption
,
Proximal tubule bicarbonate reclamation
,
Salivary secretion
,
Thyroid hormone signaling pathway
,
Thyroid hormone synthesis
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
18件:
Adrenergic signaling in cardiomyocytes
,
Aldosterone synthesis and secretion
,
Aldosterone-regula
...
3件:
8
8
,
46
,
210
💬
2.
Digoxin
×
告示番号
日本語名
英語名
8
ハンチントン病
Huntington disease
46
悪性関節リウマチ
Malignant rheumatoid arthritis
210
単心室症
Single Ventricle
3
Digoxin
0.25 mg
1件:
Digoxin
Digoxin
1件:
Digoxin
Digoxin
💬
3.
Digoxin
0.25 mg
×
Name
Other Names
Digoxin
Digoxin (JP18/USP)
Lanoxicaps (TN)
Lanoxin (TN)
DIGOX
ジゴキシン
ジゴシン
4件:
ATP1A1
ATP1A1
,
ATP1A2
,
ATP1A3
,
ATP1A4
💬
3.
Digoxin
0.25 mg
×
Name
Full Name
ATP1A1
ATPase Na+/K+ transporting subunit alpha 1
ATP1A2
ATPase Na+/K+ transporting subunit alpha 2
ATP1A3
ATPase Na+/K+ transporting subunit alpha 3
ATP1A4
ATPase Na+/K+ transporting subunit alpha 4
18件:
Adrenergic signaling in cardiomyocytes
Adrenergic signaling in cardiomyocytes
,
Aldosterone synthesis and secretion
,
Aldosterone-regulated sodium reabsorption
,
Bile secretion
,
Carbohydrate digestion and absorption
,
Cardiac muscle contraction
,
Endocrine and other factor-regulated calcium reabsorption
,
Gastric acid secretion
,
Insulin secretion
,
Mineral absorption
,
Pancreatic secretion
,
Protein digestion and absorption
,
Proximal tubule bicarbonate reclamation
,
Salivary secretion
,
Thyroid hormone signaling pathway
,
Thyroid hormone synthesis
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
18件:
Adrenergic signaling in cardiomyocytes
,
Aldosterone synthesis and secretion
,
Aldosterone-regula
...
1件:
46
46
💬
3.
Digoxin
0.25 mg
×
告示番号
日本語名
英語名
46
悪性関節リウマチ
Malignant rheumatoid arthritis
4
Montelukast, Flurbiprofen, Midazolam,
Digoxin
, Pravastatin and BMS-986142
6件:
BMS-986142
BMS-986142
,
Digoxin
,
Flurbiprofen
,
Midazolam
,
Montelukast
,
Pravastatin
5件:
Digoxin
Digoxin
,
Flurbiprofen
,
Midazolam
,
Montelukast
,
Pravastatin
💬
4. Montelukast, Flurbiprofen, Midazolam,
Digoxin
, Pravastatin and BMS-986142
×
Name
Other Names
Digoxin
Digoxin (JP18/USP)
Lanoxicaps (TN)
Lanoxin (TN)
DIGOX
ジゴキシン
ジゴシン
Flurbiprofen
Flurbiprofen (JP18/USP/INN)
Ansaid (TN)
フルルビプロフェン
アドフィード
ゼポラス
フルルバン
フロベン
ヤクバン
Midazolam
Midazolam (JAN/USP/INN)
Dormicum (TN)
Buccolam (TN)
Nayzilam (TN)
N/A
ミダゾラム
ドルミカム
ブコラム
ミダフレッサ
Montelukast
Montelukast (INN)
Brondilat (TN)
モンテルカスト
Pravastatin
Pravastatin (INN)
Pravator (TN)
プラバスタチン
24件:
ATP1A1
ATP1A1
,
ATP1A2
,
ATP1A3
,
ATP1A4
,
CYSLTR1
,
GABRA1
,
GABRA2
,
GABRA3
,
GABRA4
,
GABRA5
,
GABRA6
,
GABRB1
,
GABRB2
,
GABRB3
,
GABRD
,
GABRE
,
GABRG1
,
GABRG2
,
GABRG3
,
GABRP
,
GABRQ
,
HMGCR
,
PTGS1
,
PTGS2
💬
24件:
ATP1A1
,
ATP1A2
,
ATP1A3
,
ATP1A4
,
CYSLTR1
,
GABRA1
,
GABRA2
,
GABRA3
,
GABRA4
,
GABRA5
,
GABRA6
,
GABRB1
,
GABRB2
,
GAB
...
4. Montelukast, Flurbiprofen, Midazolam,
Digoxin
, Pravastatin and BMS-986142
×
Name
Full Name
ATP1A1
ATPase Na+/K+ transporting subunit alpha 1
ATP1A2
ATPase Na+/K+ transporting subunit alpha 2
ATP1A3
ATPase Na+/K+ transporting subunit alpha 3
ATP1A4
ATPase Na+/K+ transporting subunit alpha 4
CYSLTR1
cysteinyl leukotriene receptor 1
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
GABRA2
gamma-aminobutyric acid type A receptor subunit alpha2
GABRA3
gamma-aminobutyric acid type A receptor subunit alpha3
GABRA4
gamma-aminobutyric acid type A receptor subunit alpha4
GABRA5
gamma-aminobutyric acid type A receptor subunit alpha5
GABRA6
gamma-aminobutyric acid type A receptor subunit alpha6
GABRB1
gamma-aminobutyric acid type A receptor subunit beta1
GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
GABRB3
gamma-aminobutyric acid type A receptor subunit beta3
GABRD
gamma-aminobutyric acid type A receptor subunit delta
GABRE
gamma-aminobutyric acid type A receptor subunit epsilon
GABRG1
gamma-aminobutyric acid type A receptor subunit gamma1
GABRG2
gamma-aminobutyric acid type A receptor subunit gamma2
GABRG3
gamma-aminobutyric acid type A receptor subunit gamma3
GABRP
gamma-aminobutyric acid type A receptor subunit pi
GABRQ
gamma-aminobutyric acid type A receptor subunit theta
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
PTGS1
prostaglandin-endoperoxide synthase 1
PTGS2
prostaglandin-endoperoxide synthase 2
49件:
AMPK signaling pathway
AMPK signaling pathway
,
Adrenergic signaling in cardiomyocytes
,
Aldosterone synthesis and secretion
,
Aldosterone-regulated sodium reabsorption
,
Alzheimer disease
,
Arachidonic acid metabolism
,
Bile secretion
,
C-type lectin receptor signaling pathway
,
Calcium signaling pathway
,
Carbohydrate digestion and absorption
,
Cardiac muscle contraction
,
Chemical carcinogenesis - DNA adducts
,
Endocrine and other factor-regulated calcium reabsorption
,
GABAergic synapse
,
Gastric acid secretion
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
IL-17 signaling pathway
,
Insulin secretion
,
Kaposi sarcoma-associated herpesvirus infection
,
Leishmaniasis
,
Metabolic pathways
,
MicroRNAs in cancer
,
Mineral absorption
,
Morphine addiction
,
NF-kappa B signaling pathway
,
Neuroactive ligand-receptor interaction
,
Nicotine addiction
,
Ovarian steroidogenesis
,
Oxytocin signaling pathway
,
Pancreatic secretion
,
Pathways in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Platelet activation
,
Protein digestion and absorption
,
Proximal tubule bicarbonate reclamation
,
Regulation of lipolysis in adipocytes
,
Retrograde endocannabinoid signaling
,
Salivary secretion
,
Serotonergic synapse
,
Small cell lung cancer
,
TNF signaling pathway
,
Taste transduction
,
Terpenoid backbone biosynthesis
,
Thyroid hormone signaling pathway
,
Thyroid hormone synthesis
,
VEGF signaling pathway
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
49件:
AMPK signaling pathway
,
Adrenergic signaling in cardiomyocytes
,
Aldosterone synthesis and secre
...
1件:
46
46
💬
4. Montelukast, Flurbiprofen, Midazolam,
Digoxin
, Pravastatin and BMS-986142
×
告示番号
日本語名
英語名
46
悪性関節リウマチ
Malignant rheumatoid arthritis