Drug Description in Trials / DrugBank / KEGG DRUG

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薬物名（臨床試験情報から抽出）

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

指定難病告示番号

1

BG00002 (natalizumab)

1件: Natalizumab

1件: Natalizumab 💬

1件: ITGA4 💬

14件: Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopath ...

1件: 13 💬

2

BG00002-E (natalizumab high titer)

1件: Natalizumab

1件: Natalizumab 💬

1件: ITGA4 💬

14件: Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopath ...

1件: 13 💬

3

BG0002 (natalizumab)

1件: Natalizumab

1件: Natalizumab 💬

1件: ITGA4 💬

14件: Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopath ...

1件: 13 💬

4

Dosing Interruption of Natalizumab

1件: Natalizumab

1件: Natalizumab 💬

1件: ITGA4 💬

14件: Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopath ...

1件: 13 💬

5

Interferons, glatiramer acetate, teriflunomide, dimethyl fumarate, alemtuzumab, cladribine, fingolim ...

12件: Acetate,
Alemtuzumab,
Cladribine,
Dimethyl fumarate,
Fingolimod,
Glatiramer,
Natalizumab,
Ocrelizumab, ...

10件: Cladribine ,
Alemtuzumab ,
Rituximab ,
Dimethyl fumarate ,
Ocrelizumab ,
Natalizuma ...

Name	Other Names
Cladribine	Cladribine (JAN/USP/INN) Leustatin (TN) Mavenclad (TN) クラドリビンロイスタチン
Alemtuzumab	Alemtuzumab (USAN/INN) Alemtuzumab (genetical recombination) (JAN) Campath (TN) Lemtrada (TN) アレムツズマブマブキャンパス
Rituximab	Rituximab (USAN/INN) Rituximab (genetical recombination) (JAN) Rituximab (genetical recombination) [Rituximab biosimilar 1] (JAN) Rituximab (genetical recombination) [Rituximab biosimilar 2] (JAN) Rituximab-abbs Rituximab-pvvr Rituximab-arrx Rituxan (TN) Riabni (TN) Truximab (TN) RUXIENCE TRUXIMA リツキシマブリツキサンリツキシマブBS
Dimethyl fumarate	Dimethyl fumarate (JAN/USAN) Tecfidera (TN) フマル酸ジメチルテクフィデラ
Ocrelizumab	Ocrelizumab (USAN) Ocrelizumab (genetical recombination) (JAN) Ocrevus (TN) オクレリズマブ
Natalizumab	Natalizumab (USAN/INN) Natalizumab (genetical recombination) (JAN) Tysabri (TN) ナタリズマブタイサブリ
Ofatumumab	Ofatumumab (USAN/INN) Ofatumumab (genetical recombination) (JAN) Arzerra (TN) Kesimpta (TN) オファツムマブケシンプタ
Fingolimod	Fingolimod (INN) Gilenya (TN) フィンゴリモド
Teriflunomide	Teriflunomide (USAN) Aubagio (TN) テリフルノミド
Ponesimod	Ponesimod (USAN/INN) Ponvory (TN) ポネシモド

7件: CD52,
DHODH,
ITGA4,
KEAP1,
MS4A1,
RRM1,
S1PR1 💬

Name	Full Name
CD52	CD52 molecule
DHODH	dihydroorotate dehydrogenase (quinone)
ITGA4	integrin subunit alpha 4
KEAP1	kelch like ECH associated protein 1
MS4A1	membrane spanning 4-domains A1
RRM1	ribonucleotide reductase catalytic subunit M1
S1PR1	sphingosine-1-phosphate receptor 1

30件: Arrhythmogenic right ventricular cardiomyopathy, Biosynthesis of cofactors, Cell adhesion molec ...

1件: 13 💬

6

1件: Natalizumab

1件: Natalizumab 💬

1件: ITGA4 💬

14件: Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopath ...

5件: 13, 15, 25, 46, 96 💬

告示番号	日本語名	英語名
13	多発性硬化症／視神経脊髄炎	Multiple sclerosis/Neuromyelitis optica
15	封入体筋炎	Inclusion body myositis
25	進行性多巣性白質脳症	Progressive multifocal leukoencephalopathy
46	悪性関節リウマチ	Malignant rheumatoid arthritis
96	クローン病;回腸末端炎	Crohn disease

7

Natalizumab (BG00002)

1件: Natalizumab

1件: Natalizumab 💬

1件: ITGA4 💬

14件: Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopath ...

1件: 13 💬

8

Natalizumab (NTZ)

1件: Natalizumab

1件: Natalizumab 💬

1件: ITGA4 💬

14件: Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopath ...

1件: 13 💬

9

Natalizumab (Tysabri)

1件: Natalizumab

1件: Natalizumab 💬

1件: ITGA4 💬

14件: Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopath ...

1件: 13 💬

10

Natalizumab 300 MG in 15 ML Injection

1件: Natalizumab

1件: Natalizumab 💬

1件: ITGA4 💬

14件: Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopath ...

1件: 13 💬

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