Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1ACT-064992 (macitentan)
(Opsumit (TN))		1件: Macitentan (Opsumit)1件: Macitentan (Opsumit (TN)) 💬 2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 85 💬
2ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)
(Opsumit (TN))		4件: Bosentan,
Macitentan (Opsumit),
Sildenafil,
Tadalafil		5件: Bosentan ,
Tadalafil ,
Bosentan ,
Sildenafil ,
Macitentan (Opsumit (TN)) 💬 		3件: EDNRA,
EDNRB,
PDE5A 💬 		11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
3FDC macitentan/tadalafil
(Opsumit (TN))		2件: Macitentan (Opsumit),
Tadalafil		2件: Tadalafil ,
Macitentan (Opsumit (TN)) 💬 		3件: EDNRA,
EDNRB,
PDE5A 💬 		11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
4MACITENTAN
(Opsumit (TN))		1件: Macitentan (Opsumit)1件: Macitentan (Opsumit (TN)) 💬 2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 51, 85, 86, 88, 210 💬
5Macitentan (ACT-064992)
(Opsumit (TN))		1件: Macitentan (Opsumit)1件: Macitentan (Opsumit (TN)) 💬 2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
6Macitentan 10 mg
(Opsumit (TN))		1件: Macitentan (Opsumit)1件: Macitentan (Opsumit (TN)) 💬 2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 51, 86, 88 💬
7Macitentan 10 mg tablet, once daily.
(Opsumit (TN))		1件: Macitentan (Opsumit)1件: Macitentan (Opsumit (TN)) 💬 2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
8Macitentan 10mg
(Opsumit (TN))		1件: Macitentan (Opsumit)1件: Macitentan (Opsumit (TN)) 💬 2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 51, 88 💬
9Macitentan 3 mg
(Opsumit (TN))		1件: Macitentan (Opsumit)1件: Macitentan (Opsumit (TN)) 💬 2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 51 💬
10Macitentan 37.5 mg
(Opsumit (TN))		1件: Macitentan (Opsumit)1件: Macitentan (Opsumit (TN)) 💬 2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
11Macitentan 3mg
(Opsumit (TN))		1件: Macitentan (Opsumit)1件: Macitentan (Opsumit (TN)) 💬 2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 51 💬
12Macitentan 75 mg
(Opsumit (TN))		1件: Macitentan (Opsumit)1件: Macitentan (Opsumit (TN)) 💬 2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
13MACITENTAN COMPRESSE
(Opsumit (TN))		1件: Macitentan (Opsumit)1件: Macitentan (Opsumit (TN)) 💬 2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 86, 88 💬
14Macitentan Group
(Opsumit (TN))		1件: Macitentan (Opsumit)1件: Macitentan (Opsumit (TN)) 💬 2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
15MACITENTAN TABLETS
(Opsumit (TN))		1件: Macitentan (Opsumit)1件: Macitentan (Opsumit (TN)) 💬 2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 86, 88 💬
16Observational study with patients treated with Tracleer, Ventavis, Veletri, Opsumit and/or Uptravi4件: Epoprostenol,
Iloprost,
Macitentan (Opsumit),
Selexipag		4件: Epoprostenol ,
Iloprost ,
Selexipag ,
Macitentan (Opsumit (TN)) 💬 		3件: EDNRA,
EDNRB,
PTGIR 💬 		10件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Platelet activation, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
17Opsumit1件: Macitentan (Opsumit)1件: Macitentan (Opsumit (TN)) 💬 2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 86, 88, 210 💬
18Opsumit (macitentan)1件: Macitentan (Opsumit)1件: Macitentan (Opsumit (TN)) 💬 2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
19Opsumit 10 Mg Tablet----1件: 51 💬
20Opsumit®1件: Macitentan (Opsumit)1件: Macitentan (Opsumit (TN)) 💬 2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 86, 88, 210 💬