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Showing 1 to 10 of 20 descriptions
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No.
薬物名（臨床試験情報から抽出）
DrugBank
KEGG DRUG
KEGG GENES
KEGG PATHWAY
指定難病告示番号
1
ACT-064992 (macitentan)
(
Opsumit
)
1件:
Macitentan
Macitentan
(
Opsumit
)
1件:
Macitentan
Macitentan
(
Opsumit
)
💬
1. ACT-064992 (macitentan)
×
Name
Other Names
Macitentan
Macitentan (JAN/USAN)
Opsumit (TN)
マシテンタン
オプスミット
2件:
EDNRA
EDNRA
,
EDNRB
💬
1. ACT-064992 (macitentan)
×
Name
Full Name
EDNRA
endothelin receptor type A
EDNRB
endothelin receptor type B
9件:
Calcium signaling pathway
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Relaxin signaling pathway
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
9件:
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in c
...
1件:
85
85
💬
1. ACT-064992 (macitentan)
×
告示番号
日本語名
英語名
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
2
ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)
(
Opsumit
)
4件:
Bosentan
Bosentan
,
Macitentan
(
Opsumit
),
Sildenafil
,
Tadalafil
5件:
Bosentan
Bosentan
,
Tadalafil
,
Bosentan
,
Sildenafil
,
Macitentan
(
Opsumit
)
💬
2. ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)
×
Name
Other Names
Bosentan
Bosentan (USAN)
Bosentan hydrate (JAN)
Tracleer (TN)
ボセンタン水和物
トラクリア
ボセンタン
Tadalafil
Tadalafil (JAN/USP/INN)
Adcirca (TN)
Cialis (TN)
Zalutia (TN)
TADLIQ
ALYQ
タダラフィル
アドシルカ
ザルティア
シアリス
Bosentan
Bosentan (INN)
ボセンタン
Sildenafil
Sildenafil (INN)
Aphrodil (TN)
シルデナフィル
Macitentan
Macitentan (JAN/USAN)
Opsumit (TN)
マシテンタン
オプスミット
3件:
EDNRA
EDNRA
,
EDNRB
,
PDE5A
💬
2. ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)
×
Name
Full Name
EDNRA
endothelin receptor type A
EDNRB
endothelin receptor type B
PDE5A
phosphodiesterase 5A
11件:
Calcium signaling pathway
Calcium signaling pathway
,
Melanogenesis
,
Metabolic pathways
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Purine metabolism
,
Relaxin signaling pathway
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
11件:
Calcium signaling pathway
,
Melanogenesis
,
Metabolic pathways
,
Neuroactive ligand-receptor inter
...
1件:
86
86
💬
2. ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)
×
告示番号
日本語名
英語名
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
3
FDC macitentan/tadalafil
(
Opsumit
)
2件:
Macitentan
Macitentan
(
Opsumit
),
Tadalafil
2件:
Tadalafil
Tadalafil
,
Macitentan
(
Opsumit
)
💬
3. FDC macitentan/tadalafil
×
Name
Other Names
Tadalafil
Tadalafil (JAN/USP/INN)
Adcirca (TN)
Cialis (TN)
Zalutia (TN)
TADLIQ
ALYQ
タダラフィル
アドシルカ
ザルティア
シアリス
Macitentan
Macitentan (JAN/USAN)
Opsumit (TN)
マシテンタン
オプスミット
3件:
EDNRA
EDNRA
,
EDNRB
,
PDE5A
💬
3. FDC macitentan/tadalafil
×
Name
Full Name
EDNRA
endothelin receptor type A
EDNRB
endothelin receptor type B
PDE5A
phosphodiesterase 5A
11件:
Calcium signaling pathway
Calcium signaling pathway
,
Melanogenesis
,
Metabolic pathways
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Purine metabolism
,
Relaxin signaling pathway
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
11件:
Calcium signaling pathway
,
Melanogenesis
,
Metabolic pathways
,
Neuroactive ligand-receptor inter
...
1件:
86
86
💬
3. FDC macitentan/tadalafil
×
告示番号
日本語名
英語名
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
4
MACITENTAN
(
Opsumit
)
1件:
Macitentan
Macitentan
(
Opsumit
)
1件:
Macitentan
Macitentan
(
Opsumit
)
💬
4. MACITENTAN
×
Name
Other Names
Macitentan
Macitentan (JAN/USAN)
Opsumit (TN)
マシテンタン
オプスミット
2件:
EDNRA
EDNRA
,
EDNRB
💬
4. MACITENTAN
×
Name
Full Name
EDNRA
endothelin receptor type A
EDNRB
endothelin receptor type B
9件:
Calcium signaling pathway
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Relaxin signaling pathway
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
9件:
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in c
...
5件:
51
51
,
85
,
86
,
88
,
210
💬
4. MACITENTAN
×
告示番号
日本語名
英語名
51
全身性強皮症
Scleroderma
85
特発性間質性肺炎
Idiopathic interstitial pneumonia
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
88
慢性血栓塞栓性肺高血圧症;特発性慢性肺血栓塞栓症（肺高血圧型）
Chronic thromboembolic pulmonary hypertension
210
単心室症
Single Ventricle
5
Macitentan (ACT-064992)
(
Opsumit
)
1件:
Macitentan
Macitentan
(
Opsumit
)
1件:
Macitentan
Macitentan
(
Opsumit
)
💬
5. Macitentan (ACT-064992)
×
Name
Other Names
Macitentan
Macitentan (JAN/USAN)
Opsumit (TN)
マシテンタン
オプスミット
2件:
EDNRA
EDNRA
,
EDNRB
💬
5. Macitentan (ACT-064992)
×
Name
Full Name
EDNRA
endothelin receptor type A
EDNRB
endothelin receptor type B
9件:
Calcium signaling pathway
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Relaxin signaling pathway
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
9件:
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in c
...
1件:
86
86
💬
5. Macitentan (ACT-064992)
×
告示番号
日本語名
英語名
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
6
Macitentan 10 mg
(
Opsumit
)
1件:
Macitentan
Macitentan
(
Opsumit
)
1件:
Macitentan
Macitentan
(
Opsumit
)
💬
6. Macitentan 10 mg
×
Name
Other Names
Macitentan
Macitentan (JAN/USAN)
Opsumit (TN)
マシテンタン
オプスミット
2件:
EDNRA
EDNRA
,
EDNRB
💬
6. Macitentan 10 mg
×
Name
Full Name
EDNRA
endothelin receptor type A
EDNRB
endothelin receptor type B
9件:
Calcium signaling pathway
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Relaxin signaling pathway
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
9件:
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in c
...
3件:
51
51
,
86
,
88
💬
6. Macitentan 10 mg
×
告示番号
日本語名
英語名
51
全身性強皮症
Scleroderma
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
88
慢性血栓塞栓性肺高血圧症;特発性慢性肺血栓塞栓症（肺高血圧型）
Chronic thromboembolic pulmonary hypertension
7
Macitentan 10 mg tablet, once daily.
(
Opsumit
)
1件:
Macitentan
Macitentan
(
Opsumit
)
1件:
Macitentan
Macitentan
(
Opsumit
)
💬
7. Macitentan 10 mg tablet, once daily.
×
Name
Other Names
Macitentan
Macitentan (JAN/USAN)
Opsumit (TN)
マシテンタン
オプスミット
2件:
EDNRA
EDNRA
,
EDNRB
💬
7. Macitentan 10 mg tablet, once daily.
×
Name
Full Name
EDNRA
endothelin receptor type A
EDNRB
endothelin receptor type B
9件:
Calcium signaling pathway
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Relaxin signaling pathway
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
9件:
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in c
...
1件:
86
86
💬
7. Macitentan 10 mg tablet, once daily.
×
告示番号
日本語名
英語名
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
8
Macitentan 10mg
(
Opsumit
)
1件:
Macitentan
Macitentan
(
Opsumit
)
1件:
Macitentan
Macitentan
(
Opsumit
)
💬
8. Macitentan 10mg
×
Name
Other Names
Macitentan
Macitentan (JAN/USAN)
Opsumit (TN)
マシテンタン
オプスミット
2件:
EDNRA
EDNRA
,
EDNRB
💬
8. Macitentan 10mg
×
Name
Full Name
EDNRA
endothelin receptor type A
EDNRB
endothelin receptor type B
9件:
Calcium signaling pathway
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Relaxin signaling pathway
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
9件:
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in c
...
2件:
51
51
,
88
💬
8. Macitentan 10mg
×
告示番号
日本語名
英語名
51
全身性強皮症
Scleroderma
88
慢性血栓塞栓性肺高血圧症;特発性慢性肺血栓塞栓症（肺高血圧型）
Chronic thromboembolic pulmonary hypertension
9
Macitentan 3 mg
(
Opsumit
)
1件:
Macitentan
Macitentan
(
Opsumit
)
1件:
Macitentan
Macitentan
(
Opsumit
)
💬
9. Macitentan 3 mg
×
Name
Other Names
Macitentan
Macitentan (JAN/USAN)
Opsumit (TN)
マシテンタン
オプスミット
2件:
EDNRA
EDNRA
,
EDNRB
💬
9. Macitentan 3 mg
×
Name
Full Name
EDNRA
endothelin receptor type A
EDNRB
endothelin receptor type B
9件:
Calcium signaling pathway
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Relaxin signaling pathway
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
9件:
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in c
...
1件:
51
51
💬
9. Macitentan 3 mg
×
告示番号
日本語名
英語名
51
全身性強皮症
Scleroderma
10
Macitentan 37.5 mg
(
Opsumit
)
1件:
Macitentan
Macitentan
(
Opsumit
)
1件:
Macitentan
Macitentan
(
Opsumit
)
💬
10. Macitentan 37.5 mg
×
Name
Other Names
Macitentan
Macitentan (JAN/USAN)
Opsumit (TN)
マシテンタン
オプスミット
2件:
EDNRA
EDNRA
,
EDNRB
💬
10. Macitentan 37.5 mg
×
Name
Full Name
EDNRA
endothelin receptor type A
EDNRB
endothelin receptor type B
9件:
Calcium signaling pathway
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in cancer
,
Relaxin signaling pathway
,
Renin secretion
,
Vascular smooth muscle contraction
,
cAMP signaling pathway
,
cGMP-PKG signaling pathway
💬
9件:
Calcium signaling pathway
,
Melanogenesis
,
Neuroactive ligand-receptor interaction
,
Pathways in c
...
1件:
86
86
💬
10. Macitentan 37.5 mg
×
告示番号
日本語名
英語名
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension