KEGG DRUG

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薬物名（臨床試験情報から抽出）

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

指定難病告示番号

Busulfan/Fludarabine phosphate/Tacrolimus/Methotrexate/G-CSF

6件: Busulfan,
Filgrastim,
Fludarabine,
Methotrexate,
Phosphate ion,
Tacrolimus (Tacrolimus anhydrous)

6件: Tacrolimus (Tacrolimus, Tacrolimushydrate),
Methotrexate ,
Busulfan ,
Filgrastim ,
Flu ...

Name	Other Names
Tacrolimus	Tacrolimus (USP/INN) Tacrolimus hydrate (JP18) Prograf (TN) Protopic (TN) ASTAGRAF XL ENVARSUS タクロリムス水和物グラセプタータリムスプログラフプロトピックタクロリムス
Methotrexate	Methotrexate (JP18/USP/INN) Otrexup (TN) Xatmep (TN) REDITREX メトトレキサートメソトレキセートメトジェクトリウマトレックス
Busulfan	Busulfan (JP18/USP/INN) Myleran (TN) BUSULFEX ブスルファンブスルフェクスマブリン
Filgrastim	Filgrastim (USP/INN) Filgrastim (genetical recombination) (JP18) Filgrastim (genetical recombination) [Filgrastim biosimilar 1] (JAN) Tbo-filgrastim Filgrastim (genetical recombination) [Filgrastim biosimilar 2] (JAN) Filgrastim (genetical recombination) [Filgrastim biosimilar 3] (JAN) Filgrastim-sndz Filgrastim-aafi Neupogen (TN) Nivestym (TN) Grastofil (TN) Zarxio (TN) GRANIX RELEUKO フィルグラスチムグランフィルグラスチムBS
Fludarabine	Fludarabine (INN) Fluradosa (TN) フルダラビン
Tacrolimus	Tacrolimus (INN) Prograf (TN) タクロリムス

9件: CSF3R,
DHFR,
DHFR2,
PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2,
RRM1 💬

Name	Full Name
CSF3R	colony stimulating factor 3 receptor
DHFR	dihydrofolate reductase
DHFR2	dihydrofolate reductase 2
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta
RRM1	ribonucleotide reductase catalytic subunit M1

48件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Antifolate resistance, ...

1件: 60 💬

Glucocorticoid + tacrolimus

1件: Tacrolimus (Tacrolimus anhydrous)

2件: Tacrolimus (Tacrolimus, Tacrolimus hydrate),
Tacrolimus (Tacrolimus) 💬

Name	Other Names
Tacrolimus	Tacrolimus (USP/INN) Tacrolimus hydrate (JP18) Prograf (TN) Protopic (TN) ASTAGRAF XL ENVARSUS タクロリムス水和物グラセプタータリムスプログラフプロトピックタクロリムス
Tacrolimus	Tacrolimus (INN) Prograf (TN) タクロリムス

5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬

Name	Full Name
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell ...

1件: 222 💬

Interferon beta-1b and Tacrolimus

3件: Human interferon beta,
Interferon beta-1b,
Tacrolimus (Tacrolimus anhydrous)

3件: Tacrolimus (Tacrolimus, Tacrolimushydrate),
Interferon beta-1b ,
Tacrolimus (Tacrolimus)� ...

Name	Other Names
Tacrolimus	Tacrolimus (USP/INN) Tacrolimus hydrate (JP18) Prograf (TN) Protopic (TN) ASTAGRAF XL ENVARSUS タクロリムス水和物グラセプタータリムスプログラフプロトピックタクロリムス
Interferon beta-1b	Interferon beta-1b (USAN/INN) Interferon beta-1b (genetical recombination) (JAN) Betaseron (TN) Extavia (TN) インターフェロンベータ-1b ベタフェロン
Tacrolimus	Tacrolimus (INN) Prograf (TN) タクロリムス

7件: IFNAR1,
IFNAR2,
PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬

Name	Full Name
IFNAR1	interferon alpha and beta receptor subunit 1
IFNAR2	interferon alpha and beta receptor subunit 2
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

48件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell ...

1件: 13 💬

LCP-Tacro (tacrolimus)

1件: Tacrolimus (Tacrolimus anhydrous)

2件: Tacrolimus (Tacrolimus, Tacrolimus hydrate),
Tacrolimus (Tacrolimus) 💬

Name	Other Names
Tacrolimus	Tacrolimus (USP/INN) Tacrolimus hydrate (JP18) Prograf (TN) Protopic (TN) ASTAGRAF XL ENVARSUS タクロリムス水和物グラセプタータリムスプログラフプロトピックタクロリムス
Tacrolimus	Tacrolimus (INN) Prograf (TN) タクロリムス

5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬

Name	Full Name
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell ...

1件: 95 💬

Pyridostigmine, Prednisone, Tacrolimus

3件: Prednisone,
Pyridostigmine,
Tacrolimus (Tacrolimus anhydrous)

3件: Tacrolimus (Tacrolimus, Tacrolimus hydrate),
Prednisone ,
Tacrolimus (Tacrolimus) 💬

Name	Other Names
Tacrolimus	Tacrolimus (USP/INN) Tacrolimus hydrate (JP18) Prograf (TN) Protopic (TN) ASTAGRAF XL ENVARSUS タクロリムス水和物グラセプタータリムスプログラフプロトピックタクロリムス
Prednisone	Prednisone (USP) Prednisone monohydrate Deltasone (TN) Meticorten (TN) Rayos (TN) プレドニゾン水和物
Tacrolimus	Tacrolimus (INN) Prograf (TN) タクロリムス

6件: NR3C1,
PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬

Name	Full Name
NR3C1	nuclear receptor subfamily 3 group C member 1
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

34件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell ...

1件: 11 💬

Pyridostigmine, Tacrolimus

2件: Pyridostigmine,
Tacrolimus (Tacrolimus anhydrous)

2件: Tacrolimus (Tacrolimus, Tacrolimus hydrate),
Tacrolimus (Tacrolimus) 💬

Name	Other Names
Tacrolimus	Tacrolimus (USP/INN) Tacrolimus hydrate (JP18) Prograf (TN) Protopic (TN) ASTAGRAF XL ENVARSUS タクロリムス水和物グラセプタータリムスプログラフプロトピックタクロリムス
Tacrolimus	Tacrolimus (INN) Prograf (TN) タクロリムス

5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬

Name	Full Name
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell ...

1件: 11 💬

Rectal tacrolimus

1件: Tacrolimus (Tacrolimus anhydrous)

2件: Tacrolimus (Tacrolimus, Tacrolimus hydrate),
Tacrolimus (Tacrolimus) 💬

Name	Other Names
Tacrolimus	Tacrolimus (USP/INN) Tacrolimus hydrate (JP18) Prograf (TN) Protopic (TN) ASTAGRAF XL ENVARSUS タクロリムス水和物グラセプタータリムスプログラフプロトピックタクロリムス
Tacrolimus	Tacrolimus (INN) Prograf (TN) タクロリムス

5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬

Name	Full Name
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell ...

1件: 97 💬

Rituximab combined with tacrolimus induction + rituximab maintenance

2件: Rituximab,
Tacrolimus (Tacrolimus anhydrous)

3件: Tacrolimus (Tacrolimus, Tacrolimus hydrate),
Rituximab ,
Tacrolimus (Tacrolimus) 💬

Name	Other Names
Tacrolimus	Tacrolimus (USP/INN) Tacrolimus hydrate (JP18) Prograf (TN) Protopic (TN) ASTAGRAF XL ENVARSUS タクロリムス水和物グラセプタータリムスプログラフプロトピックタクロリムス
Rituximab	Rituximab (USAN/INN) Rituximab (genetical recombination) (JAN) Rituximab (genetical recombination) [Rituximab biosimilar 1] (JAN) Rituximab (genetical recombination) [Rituximab biosimilar 2] (JAN) Rituximab-abbs Rituximab-pvvr Rituximab-arrx Rituxan (TN) Riabni (TN) Truximab (TN) RUXIENCE TRUXIMA リツキシマブリツキサンリツキシマブBS
Tacrolimus	Tacrolimus (INN) Prograf (TN) タクロリムス

6件: MS4A1,
PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬

Name	Full Name
MS4A1	membrane spanning 4-domains A1
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

34件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell ...

1件: 222 💬

Rituximab combined with tacrolimus induction + tacrolimus maintenance

2件: Rituximab,
Tacrolimus (Tacrolimus anhydrous)

3件: Tacrolimus (Tacrolimus, Tacrolimus hydrate),
Rituximab ,
Tacrolimus (Tacrolimus) 💬

Name	Other Names
Tacrolimus	Tacrolimus (USP/INN) Tacrolimus hydrate (JP18) Prograf (TN) Protopic (TN) ASTAGRAF XL ENVARSUS タクロリムス水和物グラセプタータリムスプログラフプロトピックタクロリムス
Rituximab	Rituximab (USAN/INN) Rituximab (genetical recombination) (JAN) Rituximab (genetical recombination) [Rituximab biosimilar 1] (JAN) Rituximab (genetical recombination) [Rituximab biosimilar 2] (JAN) Rituximab-abbs Rituximab-pvvr Rituximab-arrx Rituxan (TN) Riabni (TN) Truximab (TN) RUXIENCE TRUXIMA リツキシマブリツキサンリツキシマブBS
Tacrolimus	Tacrolimus (INN) Prograf (TN) タクロリムス

6件: MS4A1,
PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬

Name	Full Name
MS4A1	membrane spanning 4-domains A1
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

34件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell ...

1件: 222 💬

Tacrolimus

1件: Tacrolimus (Tacrolimus anhydrous)

2件: Tacrolimus (Tacrolimus, Tacrolimus hydrate),
Tacrolimus (Tacrolimus) 💬

Name	Other Names
Tacrolimus	Tacrolimus (USP/INN) Tacrolimus hydrate (JP18) Prograf (TN) Protopic (TN) ASTAGRAF XL ENVARSUS タクロリムス水和物グラセプタータリムスプログラフプロトピックタクロリムス
Tacrolimus	Tacrolimus (INN) Prograf (TN) タクロリムス

5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬

Name	Full Name
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell ...

34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 16 ...

告示番号	日本語名	英語名
2	筋萎縮性側索硬化症	Amyotrophic lateral sclerosis
6	パーキンソン病	Parkinson disease
11	重症筋無力症	Myasthenia gravis
13	多発性硬化症／視神経脊髄炎	Multiple sclerosis/Neuromyelitis optica
36	表皮水疱症	Epidermolysis bullosa
46	悪性関節リウマチ	Malignant rheumatoid arthritis
49	全身性エリテマトーデス	Systemic lupus erythematosus
50	皮膚筋炎／多発性筋炎	Dermatomyositis
51	全身性強皮症	Scleroderma
53	シェーグレン症候群	Sjogren syndrome
56	ベーチェット病	Behcet disease
60	再生不良性貧血	Aplastic anemia
61	自己免疫性溶血性貧血	Autoimmune hemolytic anemia
62	発作性夜間ヘモグロビン尿症	Paroxysmal nocturnal hemoglobinuria
65	原発性免疫不全症候群	Primary immunodeficiency
66	IgA腎症	IgA nephropathy
85	特発性間質性肺炎	Idiopathic interstitial pneumonia
95	自己免疫性肝炎	Autoimmune hepatitis
96	クローン病;回腸末端炎	Crohn disease
97	潰瘍性大腸炎	Ulcerative colitis
113	筋ジストロフィー	Muscular dystrophy
151	ラスムッセン脳炎	Rasmussen encephalitis
158	結節性硬化症	Tuberous sclerosis
164	眼皮膚白皮症	Oculocutaneous albinism
222	一次性ネフローゼ症候群	Primary nephrotic syndrome
224	紫斑病性腎炎	Purpura nephritis
226	間質性膀胱炎（ハンナ型）	Interstitial cystitis with Hunners ulcer
227	オスラー病;遺伝性出血性末梢血管拡張症	Osler disease
228	閉塞性細気管支炎	Bronchiolitis obliterans
283	後天性赤芽球癆	Acquired pure red cell aplasia
284	ダイアモンド・ブラックファン貧血	Diamond-Blackfan anemia
285	ファンコニ貧血	Fanconi anemia
286	遺伝性鉄芽球性貧血	Hereditary sideroblastic anemia
299	嚢胞性線維症;膵囊胞線維症	Cystic fibrosis

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