Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)4件: Bosentan,
Macitentan,
Sildenafil,
Tadalafil		5件: Bosentan ,
Tadalafil ,
Bosentan ,
Sildenafil ,
Macitentan 💬		3件: EDNRA,
EDNRB,
PDE5A 💬		11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
2FDC macitentan/tadalafil2件: Macitentan,
Tadalafil		2件: Tadalafil ,
Macitentan 💬		3件: EDNRA,
EDNRB,
PDE5A 💬		11件: Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
3Tadalafil1件: Tadalafil1件: Tadalafil 💬1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬7件: 6, 51, 75, 84, 86, 113, 210 💬
4Tadalafil 20 MG1件: Tadalafil1件: Tadalafil 💬1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 113 💬
5Tadalafil 20 mg film-coated tablets1件: Tadalafil1件: Tadalafil 💬1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 86 💬
6Tadalafil 40 mg1件: Tadalafil1件: Tadalafil 💬1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 86 💬
7Tadalafil and ambrisentan upfront combination therapy2件: Ambrisentan,
Tadalafil		2件: Tadalafil ,
Ambrisentan 💬		2件: EDNRA,
PDE5A 💬		9件: Calcium signaling pathway, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 51, 86 💬
8Tadalafil and Sildenafil2件: Sildenafil,
Tadalafil		2件: Tadalafil ,
Sildenafil 💬		1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 113 💬
9Tadalafil Citrate1件: Tadalafil1件: Tadalafil 💬1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 210 💬
10Tadalafil oral suspension1件: Tadalafil1件: Tadalafil 💬1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 86 💬
11Tadalafil- Tablet or Oral suspension1件: Tadalafil1件: Tadalafil 💬1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 86 💬
12TADALAFILO1件: Tadalafil1件: Tadalafil 💬1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬1件: 86 💬