Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1100 MG ELX (VX-445) / 50 MG TEZ / 75 MG IVA FDC----1件: 299 💬
2100 MG ELX /50 MG TEZ /75 MG IVA FDC----1件: 299 💬
3100 MG ELX/50 MG TEZ /75 MG IVA FDC----1件: 299 💬
4100 MG ELX/50 MG TEZ/75 MG IVA fixed dose combination----1件: 299 💬
5100 MG TEZ/150 MG IVA FDC----1件: 299 💬
6100 MG VX-445 /50 MG TEZ/75 MG IVA FDC----1件: 299 💬
7100 MG VX-445/50 MG TEZ /75 MG IVA FDC----1件: 299 💬
8100-MG ELX (VX-445) / 50-MG TEZ / 75-MG IVA FDC----1件: 299 💬
9100-MG ELX (VX-455) / 50-MG TEZ / 75-MG IVA FDC----1件: 299 💬
10100-MG ELX / 50-MG TEZ / 75 -MG IVA FDC----1件: 299 💬
11100-MG VX-445 / 50-MG TEZ / 75- MG IVA FDC----1件: 299 💬
12100-MG VX-445 / 50-MG TEZ / 75-MG IVA FDC----1件: 299 💬
13100-MG VX-445/50-MG TEZ/75-MG IVA FDC----1件: 299 💬
14100G ELX / 50MG TEZ / 75MG IVA----1件: 299 💬
15100MG ELX/50MG TEZ /75MG IVA----1件: 299 💬
16100MG VX-445/50MG TEZ /75MG IVA FDC----1件: 299 💬
17150-MG ivacaftor1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
18150MG ivacaftor1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
1950 MG ELX/25 MG TEZ/37.5 MG IVA----1件: 299 💬
2050 MG ELX/25 MG TEZ/37.5 MG IVA fixed dose combination----1件: 299 💬
2175-MG ivacaftor1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
2280MG ELX / 40MG TEZ / 60MG IVA----1件: 299 💬
23CF patients with A G551D mutation and treated with ivacaftor----1件: 299 💬
24Deuterated ivacaftor1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
25Elexacaftor / ivacaftor / tezacaftor1件: Elexacaftor1件: Elexacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
26Elexacaftor 100 MG / ivacaftor 75 MG / tezacaftor 50 MG, 2 tablets each morning + ivacaftor 150 MG ONE tablet each evening1件: Elexacaftor1件: Elexacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
27Elexacaftor-tezacaftor-ivacaftor exposure1件: Elexacaftor1件: Elexacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
28Elexacaftor-tezacaftor-ivacaftor treatment1件: Elexacaftor1件: Elexacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
29Elexacaftor/tezacaftor/ivacaftor3件: Elexacaftor,
Ivacaftor (Ivacaftorum),
Tezacaftor		3件: Ivacaftor (Ivacaftor),
Tezacaftor ,
Elexacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
30ELX/TEZ/IVA----1件: 299 💬
31IVA----1件: 299 💬
32IVA 336----1件: 19 💬
33IVA337----1件: 51 💬
34Ivacaftor1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬2件: 299, 340 💬
35Ivacaftor 125MG tablet1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
36Ivacaftor 150 MG1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
37Ivacaftor 150 MG or 250 MG1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
38Ivacaftor 25 MG/75 MG1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
39Ivacaftor 59,5MG1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
40Ivacaftor 59.5MG1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
41Ivacaftor 75 MG1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
42Ivacaftor 75 MG/150 MG1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
43Ivacaftor 75MG1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
44Ivacaftor and symdeko1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
45Ivacaftor exposed1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
46Ivacaftor or elexacaftor/tezacaftor/ivacaftor1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
47Ivacaftor+lumacaftor1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
48Ivacaftor/ataluren1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
49Ivacaftor/kalydeco1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
50LUM/IVA----1件: 299 💬
51LUM/IVA fixed-dose combination----1件: 299 💬
52Lumacaftor / ivacaftor2件: Ivacaftor (Ivacaftorum),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
53Lumacaftor plus ivacaftor1件: Lumacaftor1件: Lumacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
54Lumacaftor plus ivacaftor combination2件: Ivacaftor (Ivacaftorum),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
55Lumacaftor, ivacaftor drug combination1件: Lumacaftor1件: Lumacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
56Lumacaftor-ivacaftor1件: Lumacaftor1件: Lumacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
57Lumacaftor-ivacaftor treatment1件: Lumacaftor1件: Lumacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
58Lumacaftor/ivacaftor2件: Ivacaftor (Ivacaftorum),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
59Lumacaftor/ivacaftor 100MG/125MG tablets2件: Ivacaftor (Ivacaftorum),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
60Lumacaftor/ivacaftor 200MG/125MG2件: Ivacaftor (Ivacaftorum),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
61Lumacaftor/ivacaftor 200MG/125MG tablets2件: Ivacaftor (Ivacaftorum),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
62Lumacaftor/ivacaftor 200MG/83MG tablet2件: Ivacaftor (Ivacaftorum),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
63Orkambi: contains lumacaftor and ivacaftor2件: Ivacaftor (Ivacaftorum),
Lumacaftor		2件: Ivacaftor (Ivacaftor),
Lumacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
64TEZ/IVA----1件: 299 💬
65Tezacaftor/ivacaftor2件: Ivacaftor (Ivacaftorum),
Tezacaftor		2件: Ivacaftor (Ivacaftor),
Tezacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
66Tezacaftor/ivacaftor + ivacaftor1件: Tezacaftor1件: Tezacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
67Tezacaftor/ivacaftor 100MG/150MG2件: Ivacaftor (Ivacaftorum),
Tezacaftor		2件: Ivacaftor (Ivacaftor),
Tezacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
68Tezacaftor/ivacaftor/100MG/150MG2件: Ivacaftor (Ivacaftorum),
Tezacaftor		2件: Ivacaftor (Ivacaftor),
Tezacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
69Treatment with cystic fibrosis transmembrane regulator (cftr) modualtors ivacaftor, lumacaftor-ivacaftor, tezacaftor-ivacaftor, elexacaftor-tezacaftor-ivacaftor----1件: 299 💬
70VNZ/TEZ/D-IVA----1件: 299 💬
71VX-121/TEZ/D-IVA1件: Vanzacaftor1件: Vanzacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
72VX-445 / TEZ / IVA----1件: 299 💬
73VX-445 / TEZ / IVA FDC----1件: 299 💬
74VX-445 /TEZ/IVA----1件: 299 💬
75VX-445/TEZ/IVA----1件: 299 💬
76VX-659/ TEZ/IVA----1件: 299 💬
77VX-659/TEZ/IVA----1件: 299 💬
78VX-659/tezacaftor/ivacaftor2件: Ivacaftor (Ivacaftorum),
Tezacaftor		2件: Ivacaftor (Ivacaftor),
Tezacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
79VX-661 plus ivacaftor combination1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
80VX-661/ivacaftor1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
81VX-661/ivacaftor (VX-770) 100MG/150 MG1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
82VX-661/ivacaftor 100 MG/ 150 MG1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
83VX-661/ivacaftor 100MG/150 MG1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
84VX-661/ivacaftor 100MG/150MG1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
85VX-661/ivacaftor 50 MG/ 75 MG1件: Ivacaftor (Ivacaftorum)1件: Ivacaftor (Ivacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬