Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1100 MG ELX (VX-445) / 50 MG TEZ / 75 MG IVA FDC----1件: 299 💬
2100 MG ELX /50 MG TEZ /75 MG IVA FDC----1件: 299 💬
3100 MG ELX/50 MG TEZ /75 MG IVA FDC----1件: 299 💬
4100 MG ELX/50 MG TEZ/75 MG IVA fixed dose combination----1件: 299 💬
5100 MG TEZ/150 MG IVA FDC----1件: 299 💬
6100 MG VX-445 /50 MG TEZ/75 MG IVA FDC----1件: 299 💬
7100 MG VX-445/50 MG TEZ /75 MG IVA FDC----1件: 299 💬
8100-MG ELX (VX-445) / 50-MG TEZ / 75-MG IVA FDC----1件: 299 💬
9100-MG ELX (VX-455) / 50-MG TEZ / 75-MG IVA FDC----1件: 299 💬
10100-MG ELX / 50-MG TEZ / 75 -MG IVA FDC----1件: 299 💬
11100-MG VX-445 / 50-MG TEZ / 75- MG IVA FDC----1件: 299 💬
12100-MG VX-445 / 50-MG TEZ / 75-MG IVA FDC----1件: 299 💬
13100-MG VX-445 /50-MG TEZ/75-MG----1件: 299 💬
14100-MG VX-445/50-MG TEZ/75-MG IVA FDC----1件: 299 💬
15100G ELX / 50MG TEZ / 75MG IVA----1件: 299 💬
16100MG ELX/50MG TEZ /75MG IVA----1件: 299 💬
17100MG VX-445/50MG TEZ /75MG IVA FDC----1件: 299 💬
1850 MG ELX/25 MG TEZ/37.5 MG IVA----1件: 299 💬
1950 MG ELX/25 MG TEZ/37.5 MG IVA fixed dose combination----1件: 299 💬
2080MG ELX / 40MG TEZ / 60MG IVA----1件: 299 💬
21Elexacaftor / ivacaftor / tezacaftor1件: Elexacaftor1件: Elexacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
22Elexacaftor 100 MG / ivacaftor 75 MG / tezacaftor 50 MG, 2 tablets each morning + ivacaftor 150 MG ONE tablet each evening1件: Elexacaftor1件: Elexacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
23Elexacaftor-tezacaftor-ivacaftor exposure1件: Elexacaftor1件: Elexacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
24Elexacaftor-tezacaftor-ivacaftor treatment1件: Elexacaftor1件: Elexacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
25Elexacaftor/tezacaftor/ivacaftor3件: Elexacaftor,
Ivacaftor,
Tezacaftor (Tezacaftor)		3件: Ivacaftor ,
Tezacaftor (Tezacaftor),
Elexacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
26ELX/TEZ/IVA----1件: 299 💬
27Ivacaftor or elexacaftor/tezacaftor/ivacaftor1件: Ivacaftor1件: Ivacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
28Terazosin
(TEZRULY)		1件: Terazosin2件: Terazosin hydrochloride (TEZRULY),
Terazosin 💬 		3件: ADRA1A,
ADRA1B,
ADRA1D 💬 		9件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 6 💬
29Terazosin 5 MG
(TEZRULY)		1件: Terazosin2件: Terazosin hydrochloride (TEZRULY),
Terazosin 💬 		3件: ADRA1A,
ADRA1B,
ADRA1D 💬 		9件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 6 💬
30Terazosin therapy
(TEZRULY)		1件: Terazosin2件: Terazosin hydrochloride (TEZRULY),
Terazosin 💬 		3件: ADRA1A,
ADRA1B,
ADRA1D 💬 		9件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 6 💬
31TEZ----1件: 299 💬
32TEZ/IVA----1件: 299 💬
33Teza----1件: 299 💬
34Tezacaftor1件: Tezacaftor (Tezacaftor)1件: Tezacaftor (Tezacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
35Tezacaftor/ivacaftor2件: Ivacaftor,
Tezacaftor (Tezacaftor)		2件: Ivacaftor ,
Tezacaftor (Tezacaftor) 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
36Tezacaftor/ivacaftor + ivacaftor1件: Tezacaftor (Tezacaftor)1件: Tezacaftor (Tezacaftor) 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
37Tezacaftor/ivacaftor 100MG/150MG2件: Ivacaftor,
Tezacaftor (Tezacaftor)		2件: Ivacaftor ,
Tezacaftor (Tezacaftor) 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
38Tezacaftor/ivacaftor/100MG/150MG2件: Ivacaftor,
Tezacaftor (Tezacaftor)		2件: Ivacaftor ,
Tezacaftor (Tezacaftor) 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
39Tezepelumab1件: Tezepelumab (Tezepelumab)1件: Tezepelumab (Tezepelumab, Tezepelumab, Tezepelumab-ekko, Tezspire, TEZSPIRE) 💬 1件: TSLP 💬 2件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬3件: 44, 45, 98 💬
40Tezepelumab apfs1件: Tezepelumab (Tezepelumab)1件: Tezepelumab (Tezepelumab, Tezepelumab, Tezepelumab-ekko, Tezspire, TEZSPIRE) 💬 1件: TSLP 💬 2件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬1件: 98 💬
41Tezepelumab VIA apfs1件: Tezepelumab (Tezepelumab)1件: Tezepelumab (Tezepelumab, Tezepelumab, Tezepelumab-ekko, Tezspire, TEZSPIRE) 💬 1件: TSLP 💬 2件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬1件: 98 💬
42Tezosentan1件: Tezosentan (Tezosentan)---1件: 86 💬
43Treatment with cystic fibrosis transmembrane regulator (cftr) modualtors ivacaftor, lumacaftor-ivacaftor, tezacaftor-ivacaftor, elexacaftor-tezacaftor-ivacaftor----1件: 299 💬
44VNZ/TEZ/D-IVA----1件: 299 💬
45VX-121/TEZ/D-IVA1件: Vanzacaftor1件: Vanzacaftor 💬 1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
46VX-121/tezacaftor/deutivacaftor3件: Deutivacaftor,
Tezacaftor (Tezacaftor),
Vanzacaftor		3件: Tezacaftor (Tezacaftor),
Deutivacaftor ,
Vanzacaftor 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
47VX-445 / TEZ / IVA----1件: 299 💬
48VX-445 / TEZ / IVA FDC----1件: 299 💬
49VX-445 /TEZ/IVA----1件: 299 💬
50VX-445/TEZ/IVA----1件: 299 💬
51VX-659/ TEZ/IVA----1件: 299 💬
52VX-659/TEZ/IVA----1件: 299 💬
53VX-659/tezacaftor/ivacaftor2件: Ivacaftor,
Tezacaftor (Tezacaftor)		2件: Ivacaftor ,
Tezacaftor (Tezacaftor) 💬 		1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬