KEGG DRUG

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薬物名（臨床試験情報から抽出）

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

指定難病告示番号

Amitriptyline, fluoxetine and tramadol alone (control group)
(D08623)

3件: Amitriptyline,
Fluoxetine,
Tramadol

3件: Fluoxetine ,
Amitriptyline ,
Tramadol (D08623) 💬

Name	Other Names
Fluoxetine	Fluoxetine (USAN/INN) Fluoxetine (TN) フルオキセチン
Amitriptyline	Amitriptyline (INN) Laroxyl (TN) アミトリプチリン
Tramadol	Tramadol (INN) Amanda (TN) トラマドール

3件: OPRM1,
SLC6A2,
SLC6A4 💬

5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Seroton ...

1件: 78 💬

Sc recombinant growth hormone + amitriptyline, fluoxetine and tramadol (treated group)
(D08623)

4件: Amitriptyline,
Fluoxetine,
Somatotropin,
Tramadol

3件: Fluoxetine ,
Amitriptyline ,
Tramadol (D08623) 💬

Name	Other Names
Fluoxetine	Fluoxetine (USAN/INN) Fluoxetine (TN) フルオキセチン
Amitriptyline	Amitriptyline (INN) Laroxyl (TN) アミトリプチリン
Tramadol	Tramadol (INN) Amanda (TN) トラマドール

3件: OPRM1,
SLC6A2,
SLC6A4 💬

5件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Seroton ...

1件: 78 💬

Tramadol
(D08623)

1件: Tramadol

1件: Tramadol (D08623) 💬

1件: OPRM1 💬

3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬

5件: 46, 70, 78, 226, 271 💬

告示番号	日本語名	英語名
46	悪性関節リウマチ	Malignant rheumatoid arthritis
70	広範脊柱管狭窄症	Spinal stenosis
78	下垂体前葉機能低下症	Hypopituitarism
226	間質性膀胱炎（ハンナ型）	Interstitial cystitis with Hunners ulcer
271	強直性脊椎炎	Ankylosing spondylitis

Tramadol /acetaminophen
(D08623)

2件: Acetaminophen,
Tramadol

2件: Acetaminophen ,
Tramadol (D08623) 💬

Name	Other Names
Acetaminophen	Acetaminophen (JP18/USP) Paracetamol (INN) Tylenol (TN) OFIRMEV GOOD NEIGHBOR PHARMACY PAIN RELIEF アセトアミノフェンパラセタモールアセリオアルピニーアンヒバカロナールピレチノール
Tramadol	Tramadol (INN) Amanda (TN) トラマドール

3件: OPRM1,
PTGS1,
PTGS2 💬

26件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemi ...

1件: 271 💬

Tramadol hydrochloride + acetaminophen
(D08623)

2件: Acetaminophen,
Tramadol

2件: Acetaminophen ,
Tramadol (D08623) 💬

Name	Other Names
Acetaminophen	Acetaminophen (JP18/USP) Paracetamol (INN) Tylenol (TN) OFIRMEV GOOD NEIGHBOR PHARMACY PAIN RELIEF アセトアミノフェンパラセタモールアセリオアルピニーアンヒバカロナールピレチノール
Tramadol	Tramadol (INN) Amanda (TN) トラマドール

3件: OPRM1,
PTGS1,
PTGS2 💬

26件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemi ...

1件: 46 💬

Tramadol with ropivacaine
(D08623)

2件: Ropivacaine,
Tramadol

2件: Ropivacaine ,
Tramadol (D08623) 💬

6件: OPRM1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬

Name	Full Name
OPRM1	opioid receptor mu 1
SCN1A	sodium voltage-gated channel alpha subunit 1
SCN2A	sodium voltage-gated channel alpha subunit 2
SCN3A	sodium voltage-gated channel alpha subunit 3
SCN5A	sodium voltage-gated channel alpha subunit 5
SCN9A	sodium voltage-gated channel alpha subunit 9

6件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Estrogen signaling pathway, Morphi ...

1件: 70 💬

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