Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetate 1件: Acetate---41件: 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299 💬
2 Blarcamesine 1件: Blarcamesine1件: Blarcamesine 💬6件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
SIGMAR1 💬		14件: Alzheimer disease, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬1件: 156 💬
3 Butyric Acid 4件: Butanoic acid; Butyrate; Butyric Acid; Sodium Butyrate---7件: 34, 46, 51, 97, 156, 222, 291 💬
4 Calcium 2件: Calcio; Calcium---27件: 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299 💬
5 Cannabidiol 4件: CANNABIDIOL; Epidiolex; Epidyolex; SATIVEX1件: Cannabidiol 💬2件: CNR1,
CNR2 💬		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬20件: 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
6 Creatine 1件: Creatine---11件: 1, 2, 5, 6, 8, 46, 49, 50, 113, 156, 201 💬
7 Desipramine 1件: Desipramine1件: Desipramine 💬2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 120, 156 💬
8 Dextromethorphan 4件: Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta1件: Dextromethorphan 💬6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
9 Donepezil 3件: Aricept; Donepezil; Donepezil hydrochloride1件: Donepezil 💬1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬9件: 5, 6, 13, 46, 78, 124, 127, 156, 206 💬
10 Fingolimod 3件: FINGOLIMOD; FINGOLIMOD HYDROCHLORIDE; GILENYA1件: Fingolimod 💬1件: S1PR1 💬3件: FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬3件: 13, 14, 156 💬
11 Glatiramer 5件: COP-1; COPAXONE; Copolymer-1; Glatiramer; Glatiramer acetate---4件: 2, 13, 96, 156 💬
12 Insulin human 1件: Human insulin1件: Insulin human 💬1件: INSR 💬22件: AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬2件: 96, 156 💬
13 Inulin 1件: Inulin1件: Inulin 💬--4件: 6, 96, 156, 299 💬
14 Ketamine 2件: Ketamine; NMDA1件: Ketamine 💬5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬8件: 2, 4, 6, 13, 70, 113, 156, 215 💬
15 Lactobacillus plantarum 1件: Lactobacillus plantarum---3件: 6, 97, 156 💬
16 Lovastatin 1件: Lovastatin1件: Lovastatin 💬1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬11件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
17 Risperidone 1件: Risperidone1件: Risperidone 💬2件: DRD2,
HTR2A 💬		11件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬5件: 8, 156, 179, 187, 206 💬
18 Sarizotan 1件: Sarizotan---2件: 6, 156 💬
19 Tocotrienol 1件: Tocotrienol---3件: 21, 156, 299 💬
20 Topiramate 2件: TOPAMAX; TOPIRAMATE1件: Topiramate 💬36件: CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		53件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 6, 97, 140, 144, 156, 193 💬
21 Triheptanoin 1件: TRIHEPTANOIN1件: Triheptanoin 💬--10件: 2, 8, 65, 149, 156, 248, 256, 257, 317, 324 💬
22 Trofinetide 1件: Trofinetide1件: Trofinetide 💬--1件: 156 💬
23 Zinc oxide 1件: Zinc oxide1件: Zinc oxide 💬--1件: 156 💬