Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Ambroxol
(trans-4-cyclohexanol)		2件: Ambroxol; Ambroxol hydrochloride2件: Ambroxol hydrochloride ,
Ambroxol 💬 		--3件: 2, 6, 19 💬
2 Amitriptyline
(5-cycloheptene)		2件: Amitriptyline; Amitriptyline hydrochloride2件: Amitriptyline hydrochloride ,
Amitriptyline 💬 		2件: SLC6A2,
SLC6A4 💬 		3件: Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬3件: 97, 226, 299 💬
3 Anlotinib
(1-cyclopropan-amine)		1件: Anlotinib1件: Catequentinib 💬 10件: FGFR1,
FGFR2,
FGFR3,
FGFR4,
FLT1,
FLT4,
KDR,
KIT,
PDGFRA,
PDGFRB 💬 		36件: Acute myeloid leukemia, Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬1件: 85 💬
4 BMS-986278
(cyclohexane-1-carboxylic acid)		1件: BMS-986278---1件: 85 💬
5 Bromocriptine 1件: Bromocriptine2件: Bromocriptine mesylate (CYCLOSET),
Bromocriptine 💬 		2件: DRD2,
PRL 💬 		14件: Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 6, 74 💬
6 Bucladesine
(dibutyryl cyclic AMP)		1件: Bucladesine1件: Bucladesine 💬 16件: PDE1,
PDE1,
PDE1,
PDE10,
PDE11,
PDE2A,
PDE3A,
PDE3B,
PDE4,
PDE4,
PDE4,
PDE4,
PDE7,
PDE7,
PDE8,
PDE8 💬 		17件: Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 246 💬
7 Ciprofloxacin
(1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid)		2件: Ciprofloxacin; Ciprofloxacin hydrochloride3件: Ciprofloxacin ,
Ciprofloxacin hydrochloride ,
Ciprofloxacin lactate 💬 		--6件: 2, 46, 60, 96, 97, 299 💬
8 Cyclic adenosine monophosphate
(Cyclic adenosine monophosphate)		1件: Ampc---1件: 84 💬
9 Cyclophosphamide
(Cyclophosphamid)		5件: Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamide monohydrate2件: Cyclophosphamide (Cyclophosphamide, Cyclophosphamide hydrate, CYCLOPHOSPHAMIDE),
Cyclophosphamide (Cyclophosphamide, Cyclophosphamide) 💬 		--46件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 93, 96, 162, 164, 172, 205, 220, 221, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
10 Cycloserine
(Cycloserine)		1件: Cycloserine1件: Cycloserine (Cycloserine) 💬 --1件: 2 💬
11 Cyclosporine
(Cyclosporin)		6件: Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine1件: Cyclosporine (Cyclosporine, CYCLOSPORINE, CYCLOSPORINE, MODFIED) 💬 5件: PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬42件: 11, 19, 20, 26, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 54, 55, 56, 58, 60, 61, 62, 63, 64, 65, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
12 Esketamine
(cyclohexanone)		3件: Esketamine; Esketamine hydrochloride; Ketamine2件: Esketamine ,
Esketamine hydrochloride 💬 		5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		21件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬7件: 2, 4, 6, 70, 96, 97, 156 💬
13 Esuberaprost
(1h-cyclopenta-)		1件: Esuberaprost2件: Esuberaprost ,
Esuberaprost sodium 💬 		1件: PTGIR 💬 3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬1件: 86 💬
14 Gabapentin
(1-cyclohexaneacetic acid)		2件: Gabapentin; Gabapentine1件: Gabapentin 💬 5件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬 		10件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Neuroactive ligand signaling, Oxytocin signaling pathway, Synaptic vesicle cycle 💬5件: 6, 13, 19, 70, 298 💬
15 Hydroxypropyl betadex
(Hydroxypropyl beta cyclodextrin)		1件: 2-hydroxypropyl-BETA-cyclodextrin---1件: 19 💬
16 Ketamine
(2--2-methylamino-cyclohexanone)		3件: Ketamine; Ketamine hydrochloride; Nmda2件: Ketamine hydrochloride ,
Ketamine 💬 		5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		21件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬6件: 6, 13, 70, 113, 156, 215 💬
17 Montelukast
(cyclopropaneacetic acid)		2件: Montelukast; Montelukast sodium2件: Montelukast sodium ,
Montelukast 💬 		1件: CYSLTR1 💬 2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬9件: 6, 13, 19, 46, 61, 63, 85, 98, 228 💬
18 Naltrexone
(N-Cyclopropylmethylnoroxymorphone)		2件: Naltrexone; Naltrexone hydrochloride2件: Naltrexone hydrochloride ,
Naltrexone 💬 		3件: OPRD1,
OPRK1,
OPRM1 💬 		7件: Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬12件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
19 NNZ-2591
(Cyclo)		1件: NNZ-2591---2件: 193, 201 💬
20 Oseltamivir
(Ethyl -1-cyclohexene-1-carboxylate)		1件: Oseltamivir2件: Oseltamivir phosphate ,
Oseltamivir 💬 		--2件: 97, 299 💬
21 Oxybutynin
(4-Diethylamino-2-butinyl alpha-cyclohexylmandelat)		0件: 2件: Oxybutynin ,
Oxybutynin chloride 💬 		5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		14件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬3件: 6, 13, 53 💬
22 Pasireotide
(cyclo)		4件: Pasireotida; Pasireotide; Pasireotide diaspartate; Pasireotide pamoate3件: Pasireotide ,
Pasireotide diaspartate ,
Pasireotide pamoate 💬 		4件: SSTR1,
SSTR2,
SSTR3,
SSTR5 💬 		5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬4件: 67, 74, 75, 77 💬
23 Tenocyclidine
(Thienyl cyclohexylpiperidine)		0件: 1件: Tenocyclidine 💬 5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		21件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬1件: 36 💬
24 Tranexamic acid
(trans-4-cyclohexanecarboxylic acid)		1件: Tranexamic acid1件: Tranexamic acid 💬 1件: PLG 💬 4件: Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬8件: 46, 65, 70, 215, 227, 274, 288, 299 💬