Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Bevantolol
(1--3-m-tolyloxy-propan-2-ol)		1件: Bevantolol hydrochloride1件: Bevantolol hydrochloride 💬 8件: ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		44件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gap junction, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hormone signaling, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 8 💬
2 Cotoretigene toliparvovec
(Cotoretigene toliparvovec)		3件: AAV8-rpgr; BIIB112; Cotoretigene toliparvovec---1件: 90 💬
3 Imatinib
(α--p-toluidide)		2件: Imatinib; Imatinib mesylate2件: Imatinib mesylate ,
Imatinib 💬 		3件: ABL1,
KIT,
PDGFRA 💬 		31件: Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
4 Itraconazole 1件: Itraconazole1件: Itraconazole (TOLSURA) 💬 --8件: 2, 3, 46, 65, 96, 97, 227, 299 💬
5 Milnacipran 1件: Milnacipran2件: Milnacipran hydrochloride (Toledomin),
Milnacipran 💬 		2件: SLC6A2,
SLC6A4 💬 		3件: Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬2件: 46, 49 💬
6 Tolcapone
(Tolcaponum)		2件: Tolcapon; Tolcapone1件: Tolcapone (Tolcapone, TOLCAPONE) 💬 1件: COMT 💬 3件: Dopaminergic synapse, Steroid hormone biosynthesis, Tyrosine metabolism 💬3件: 6, 28, 127 💬
7 Tolebrutinib
(Tolebrutinib)		1件: Tolebrutinib1件: Tolebrutinib (Tolebrutinib) 💬 1件: BTK 💬 7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬2件: 11, 13 💬
8 Tolfenamic acid
(Tolfenamic acid)		1件: Tolfenamic acid1件: Tolfenamic acid (Tolfenamic acid) 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 5 💬
9 Tolperisone
(Tolperisone)		0件: 2件: Tolperisone hydrochloride (Tolperisone hydrochloride),
Tolperisone (Tolperisone) 💬 		--1件: 13 💬
10 Tolterodine
(Tolterodina)		1件: Tolterodine2件: Tolterodine (Tolterodine),
Tolterodine tartrate (Tolterodine tartrate, TOLTERODINE TARTRATE, TOLTERODINE TARTRATE EXTENDED RELEASE) 💬 		1件: CHRM3 💬 12件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬1件: 17 💬
11 Tolvaptan
(Tolvaptan)		1件: Tolvaptan1件: Tolvaptan (Tolvaptan, TOLVAPTAN) 💬 1件: AVPR2 💬 4件: Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬4件: 67, 72, 86, 225 💬