Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Testosterone 💬1件: Testosterone1件: Testosterone1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬8件: 1, 2, 3, 13, 60, 76, 78, 113 💬
2 Acetaminophen 💬1件: Acetaminophen4件: Acetaminophen; PARACETAMOL; Tylenol; Ultracet2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
3 Hydroxyurea 💬1件: Hydroxyurea1件: Hydroxyurea1件: RRM2 💬 7件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬8件: 3, 13, 19, 20, 65, 85, 86, 284 💬
4 Itraconazole 💬1件: Itraconazole2件: Itraconazole; Sporanox--6件: 3, 46, 65, 96, 227, 299 💬
5 Valproic acid 💬1件: Valproic acid3件: Valproate; VALPROATE SODIUM; Valproic Acid7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬 		17件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬10件: 2, 3, 5, 26, 65, 90, 102, 222, 233, 256 💬
6 Prednisolone 💬1件: Prednisolone3件: Prednisolona; Prednisolone; Prednisolonum1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬42件: 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
7 Midazolam 💬1件: Midazolam2件: Midazolam; Midazolam injection16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬12件: 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
8 Celecoxib 💬1件: Celecoxib2件: CELEBREX; CELECOXIB1件: PTGS2 💬 22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬10件: 2, 3, 34, 46, 70, 89, 107, 161, 171, 271 💬
9 Riluzole 💬1件: Riluzole2件: Rilutek; Riluzole14件: GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		23件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬9件: 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
10 Albuterol 💬1件: Salbutamol3件: Albuterol; Salbutamol; Ventolin1件: ADRB2 💬 9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬12件: 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
11 Levocarnitine 💬1件: Levocarnitine4件: Carnitine; L-Carnitine; LEVOCARNITINE; Xyzal--11件: 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316 💬
12 Sesame oil 💬1件: Sesame oil1件: Sesame oil--1件: 3 💬
13 Dalfampridine 💬1件: Dalfampridine7件: 4-Aminopyridine; 4-AP; Ampyra; Dalfampridine; FAMPRIDINA; FAMPRIDINE; Fampyra4件: KCNA4,
KCNC3,
KCND2,
KCND3 💬 		4件: Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬5件: 3, 4, 6, 13, 14 💬
14 Amifampridine 💬1件: Amifampridine2件: Amifampridine; Firdapse4件: KCNA4,
KCNC3,
KCND2,
KCND3 💬 		4件: Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬3件: 3, 11, 12 💬
15 Nusinersen 💬1件: Nusinersen2件: NUSINERSEN; Spinraza1件: SMN2 💬 1件: 💬1件: 3 💬
16 Olesoxime 💬1件: Olesoxime1件: Olesoxime--3件: 2, 3, 13 💬
17 Taldefgrobep alfa 💬1件: Talditercept alfa1件: Taldefgrobep alfa1件: MSTN 💬 1件: Cytokine-cytokine receptor interaction 💬1件: 3 💬
18 Reldesemtiv 💬1件: Reldesemtiv2件: CK-2127107; Reldesemtiv1件: TNNC2 💬 1件: Calcium signaling pathway 💬2件: 2, 3 💬
19 Risdiplam 💬1件: Risdiplam2件: EVRYSDI; Risdiplam1件: SMN2 💬 1件: Nucleocytoplasmic transport 💬1件: 3 💬
20 Onasemnogene abeparvovec 💬1件: Onasemnogene abeparvovec3件: ONASEMNOGENE ABEPARVOVEC; Onasemnogene Abeparvovec-xioi; Zolgensma1件: SMN1 💬 1件: 💬1件: 3 💬
21 Apitegromab 💬1件: Apitegromab1件: Apitegromab1件: MSTN 💬 1件: Cytokine-cytokine receptor interaction 💬1件: 3 💬
22 Branaplam 💬1件: Branaplam1件: BRANAPLAM1件: SMN2 💬 1件: 💬2件: 3, 8 💬