Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MPO 1件: MPO 💬
|
Verdiperstat Verdiperstat 💬
| Verdiperstat | 002 3件: 2 , 17, 127 💬
|
2 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
3 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
ADRA1A 6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNQ1, SCN5A 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
4 | Alanine, aspartate and glutamate metabolism 💬 5 genes, 3 drugs (DrugBank) and 19 diseases |
ABAT 4件: ABAT, ALDH5A1, GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
5 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
6 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 4件: 6 , 8 , 13, 127 💬
|
7 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
8 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
9 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
KCNJ5 1件: KCNJ5 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
10 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 4件: 6 , 8 , 13, 127 💬
|
11 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
12 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MAPT 1件: MAPT 💬
|
Flortaucipir F 18 Flortaucipir F 18 💬
| Flortaucipir | 005 3件: 5 , 7 , 127 💬
|
13 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MAPT 1件: MAPT 💬
|
Hydromethylthionine mesylate Hydromethylthionine mesylate 💬
| Hydromethylthionine mesylate | 127 1件: 127 💬
|
14 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 4件: 6 , 8 , 13, 127 💬
|
15 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
16 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
ADRA1A 1件: ADRA1A 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
17 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
18 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 4件: 6 , 8 , 13, 127 💬
|
19 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
20 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
21 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
22 | beta-Alanine metabolism 💬 4 genes, 3 drugs (DrugBank) and 17 diseases |
ABAT 3件: ABAT, GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
23 | Butanoate metabolism 💬 4 genes, 2 drugs (DrugBank) and 16 diseases |
ABAT 4件: ABAT, ALDH5A1, GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
24 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADRA1A 4件: ADRA1A, ADRA1B, ADRA1D, ADRB1 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
25 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
26 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
GRIN1 4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 4件: 6 , 8 , 13, 127 💬
|
27 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
GRIN1 4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
28 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
OXTR 1件: OXTR 💬
|
Oxytocin Oxytocin 💬
| Oxytocin | 006 7件: 6 , 72, 127, 168, 193, 206, 226 💬
|
29 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADRB1 1件: ADRB1 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
30 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 4件: 6 , 8 , 13, 127 💬
|
31 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
32 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
OXTR 1件: OXTR 💬
|
Oxytocin Oxytocin 💬
| Oxytocin | 006 7件: 6 , 72, 127, 168, 193, 206, 226 💬
|
33 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADRA1A 5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNJ8 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
34 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
ADRB1 1件: ADRB1 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
35 | Cholesterol metabolism 💬 6 genes, 8 drugs (DrugBank) and 6 diseases |
SORT1 1件: SORT1 💬
|
Latozinemab Latozinemab 💬
| Latozinemab | 002 2件: 2 , 127 💬
|
36 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
ACHE 1件: ACHE 💬
|
Donepezil Donepezil 💬
| Donepezil | 005 9件: 5 , 6 , 13, 46, 78, 124, 127, 156, 206 💬
|
37 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
ACHE 1件: ACHE 💬
|
Galantamine Galantamine 💬
| Galantamine | 006 2件: 6 , 127 💬
|
38 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
KCNJ12 3件: KCNJ12, KCNJ3, KCNQ1 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
39 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
40 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 4件: 6 , 8 , 13, 127 💬
|
41 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
42 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
KCNJ3 2件: KCNJ3, KCNJ5 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
43 | Circadian rhythm 💬 2 genes, 1 drug (DrugBank) and 25 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
44 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 4件: 6 , 8 , 13, 127 💬
|
45 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
46 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
47 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
48 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ADRB1 1件: ADRB1 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
49 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
COMT 1件: COMT 💬
|
Tolcapone Tolcapone 💬
| Tolcapone | 006 3件: 6 , 28, 127 💬
|
50 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
GRIN2A 2件: GRIN2A, GRIN2B 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 4件: 6 , 8 , 13, 127 💬
|
51 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
GRIN2A 2件: GRIN2A, GRIN2B 💬
|
Memantine Memantine 💬
| Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
52 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
KCNJ3 3件: KCNJ3, KCNJ5, SCN1A 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
53 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 48 diseases |
MPO 1件: MPO 💬
|
Verdiperstat Verdiperstat 💬
| Verdiperstat | 002 3件: 2 , 17, 127 💬
|
54 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
KCNJ3 2件: KCNJ3, KCNJ5 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
55 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
56 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
57 | GABAergic synapse 💬 29 genes, 38 drugs (DrugBank) and 55 diseases |
ABAT 3件: ABAT, GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
58 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
ADRB1 1件: ADRB1 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
59 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
KCNQ1 1件: KCNQ1 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
60 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
61 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 4件: 6 , 8 , 13, 127 💬
|
62 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
63 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
KCNJ3 1件: KCNJ3 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
64 | Glycerophospholipid metabolism 💬 1 gene, 5 drugs (DrugBank) and 11 diseases |
ACHE 1件: ACHE 💬
|
Donepezil Donepezil 💬
| Donepezil | 005 9件: 5 , 6 , 13, 46, 78, 124, 127, 156, 206 💬
|
65 | Glycerophospholipid metabolism 💬 1 gene, 5 drugs (DrugBank) and 11 diseases |
ACHE 1件: ACHE 💬
|
Galantamine Galantamine 💬
| Galantamine | 006 2件: 6 , 127 💬
|
66 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
67 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
KCNJ11 3件: KCNJ11, KCNJ3, KCNJ5 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
68 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
GRIN1 2件: GRIN1, GRIN2B 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 4件: 6 , 8 , 13, 127 💬
|
69 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
GRIN1 2件: GRIN1, GRIN2B 💬
|
Memantine Memantine 💬
| Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
70 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
71 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
72 | Insulin secretion 💬 14 genes, 39 drugs (DrugBank) and 44 diseases |
KCNJ11 1件: KCNJ11 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
73 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
74 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 4件: 6 , 8 , 13, 127 💬
|
75 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
76 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
77 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
78 | Lysosome 💬 14 genes, 24 drugs (DrugBank) and 6 diseases |
SORT1 1件: SORT1 💬
|
Latozinemab Latozinemab 💬
| Latozinemab | 002 2件: 2 , 127 💬
|
79 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CACNA1G 3件: CACNA1G, CACNA1H, CACNA1I 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
80 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAPT 1件: MAPT 💬
|
Flortaucipir F 18 Flortaucipir F 18 💬
| Flortaucipir | 005 3件: 5 , 7 , 127 💬
|
81 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
MAPT 1件: MAPT 💬
|
Hydromethylthionine mesylate Hydromethylthionine mesylate 💬
| Hydromethylthionine mesylate | 127 1件: 127 💬
|
82 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ABAT 4件: ABAT, ALDH5A1, GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
83 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
COMT 1件: COMT 💬
|
Tolcapone Tolcapone 💬
| Tolcapone | 006 3件: 6 , 28, 127 💬
|
84 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
KCNJ3 2件: KCNJ3, KCNJ5 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
85 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
86 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADRA1A 4件: ADRA1A, ADRA1B, ADRA1D, ADRB1 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
87 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CNR1 2件: CNR1, CNR2 💬
|
Nabilone Nabilone 💬
| Nabilone | 006 3件: 6 , 13, 127 💬
|
88 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 4件: 6 , 8 , 13, 127 💬
|
89 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
90 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
OXTR 1件: OXTR 💬
|
Oxytocin Oxytocin 💬
| Oxytocin | 006 7件: 6 , 72, 127, 168, 193, 206, 226 💬
|
91 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
SORT1 1件: SORT1 💬
|
Latozinemab Latozinemab 💬
| Latozinemab | 002 2件: 2 , 127 💬
|
92 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MPO 1件: MPO 💬
|
Verdiperstat Verdiperstat 💬
| Verdiperstat | 002 3件: 2 , 17, 127 💬
|
93 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 4件: 6 , 8 , 13, 127 💬
|
94 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
95 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
96 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
KCNJ12 3件: KCNJ12, KCNJ3, KCNJ5 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
97 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
OXTR 1件: OXTR 💬
|
Oxytocin Oxytocin 💬
| Oxytocin | 006 7件: 6 , 72, 127, 168, 193, 206, 226 💬
|
98 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
99 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
KCNQ1 1件: KCNQ1 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
100 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
MAPT 1件: MAPT 💬
|
Flortaucipir F 18 Flortaucipir F 18 💬
| Flortaucipir | 005 3件: 5 , 7 , 127 💬
|
101 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
MAPT 1件: MAPT 💬
|
Hydromethylthionine mesylate Hydromethylthionine mesylate 💬
| Hydromethylthionine mesylate | 127 1件: 127 💬
|
102 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 4件: 6 , 8 , 13, 127 💬
|
103 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
104 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAPT 1件: MAPT 💬
|
Flortaucipir F 18 Flortaucipir F 18 💬
| Flortaucipir | 005 3件: 5 , 7 , 127 💬
|
105 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MAPT 1件: MAPT 💬
|
Hydromethylthionine mesylate Hydromethylthionine mesylate 💬
| Hydromethylthionine mesylate | 127 1件: 127 💬
|
106 | Phagosome 💬 13 genes, 10 drugs (DrugBank) and 21 diseases |
MPO 1件: MPO 💬
|
Verdiperstat Verdiperstat 💬
| Verdiperstat | 002 3件: 2 , 17, 127 💬
|
107 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
108 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 4件: 6 , 8 , 13, 127 💬
|
109 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
110 | Propanoate metabolism 💬 1 gene, 2 drugs (DrugBank) and 16 diseases |
ABAT 1件: ABAT 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
111 | Protein digestion and absorption 💬 7 genes, 7 drugs (DrugBank) and 13 diseases |
KCNQ1 1件: KCNQ1 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
112 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
CNR1 1件: CNR1 💬
|
Nabilone Nabilone 💬
| Nabilone | 006 3件: 6 , 13, 127 💬
|
113 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
GRIN1 3件: GRIN1, GRIN2A, GRIN2B 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 4件: 6 , 8 , 13, 127 💬
|
114 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
GRIN1 3件: GRIN1, GRIN2A, GRIN2B 💬
|
Memantine Memantine 💬
| Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
115 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
GRIN1 3件: GRIN1, GRIN2A, GRIN2B 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 4件: 6 , 8 , 13, 127 💬
|
116 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
GRIN1 3件: GRIN1, GRIN2A, GRIN2B 💬
|
Memantine Memantine 💬
| Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
117 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
ADRB1 1件: ADRB1 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
118 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
ADRB1 1件: ADRB1 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
119 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
CNR1 1件: CNR1 💬
|
Nabilone Nabilone 💬
| Nabilone | 006 3件: 6 , 13, 127 💬
|
120 | Retrograde endocannabinoid signaling 💬 34 genes, 62 drugs (DrugBank) and 67 diseases |
KCNJ3 2件: KCNJ3, KCNJ5 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
121 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
ADRA1A 4件: ADRA1A, ADRA1B, ADRA1D, ADRB1 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
122 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
KCNJ3 2件: KCNJ3, KCNJ5 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
123 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
SLC6A4 1件: SLC6A4 💬
|
Citalopram Citalopram 💬
| Citalopram | 006 7件: 6 , 8 , 13, 18, 46, 98, 127 💬
|
124 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 4件: 6 , 8 , 13, 127 💬
|
125 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬
|
Memantine Memantine 💬
| Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
126 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
KCND3 1件: KCND3 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
127 | Steroid hormone biosynthesis 💬 8 genes, 11 drugs (DrugBank) and 14 diseases |
COMT 1件: COMT 💬
|
Tolcapone Tolcapone 💬
| Tolcapone | 006 3件: 6 , 28, 127 💬
|
128 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A4 1件: SLC6A4 💬
|
Citalopram Citalopram 💬
| Citalopram | 006 7件: 6 , 8 , 13, 18, 46, 98, 127 💬
|
129 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
GRIN2A 2件: GRIN2A, GRIN2B 💬
|
Amantadine Amantadine 💬
| Amantadine | 006 4件: 6 , 8 , 13, 127 💬
|
130 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
GRIN2A 2件: GRIN2A, GRIN2B 💬
|
Memantine Memantine 💬
| Memantine | 002 8件: 2 , 6 , 8 , 13, 49, 127, 205, 206 💬
|
131 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
SCN2A 3件: SCN2A, SCN3A, SCN9A 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
132 | Taurine and hypotaurine metabolism 💬 2 genes, 1 drug (DrugBank) and 14 diseases |
GAD1 2件: GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
133 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
CNR1 1件: CNR1 💬
|
Nabilone Nabilone 💬
| Nabilone | 006 3件: 6 , 13, 127 💬
|
134 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
135 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
|
Metformin Metformin 💬
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
|
136 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
MPO 1件: MPO 💬
|
Verdiperstat Verdiperstat 💬
| Verdiperstat | 002 3件: 2 , 17, 127 💬
|
137 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
GAD1 2件: GAD1, GAD2 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
138 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
CACNA1G 1件: CACNA1G 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
139 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
KCNJ11 1件: KCNJ11 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
140 | Tyrosine metabolism 💬 10 genes, 16 drugs (DrugBank) and 18 diseases |
COMT 1件: COMT 💬
|
Tolcapone Tolcapone 💬
| Tolcapone | 006 3件: 6 , 28, 127 💬
|
141 | Valine, leucine and isoleucine degradation 💬 1 gene, 2 drugs (DrugBank) and 16 diseases |
ABAT 1件: ABAT 💬
|
Valproic acid Valproic acid 💬
| Valproic acid | 002 14件: 2 , 3 , 5 , 6 , 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬
|
142 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|
143 | Vibrio cholerae infection 💬 3 genes, 10 drugs (DrugBank) and 8 diseases |
KCNQ1 1件: KCNQ1 💬
|
Amiodarone Amiodarone 💬
| Amiodarone | 028 2件: 28, 127 💬
|