Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 2 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 3 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
IL1A 2件: IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 4 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 5 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 6 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 7 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
IL1A 2件: IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 8 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 9 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Colchicine Colchicine 💬 |
Colchicine | 002 7件: 2 , 42, 46, 56, 93, 210, 266 💬 💬 |
| 10 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 11 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 12 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
| 13 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Colchicine Colchicine 💬 |
Colchicine | 002 7件: 2 , 42, 46, 56, 93, 210, 266 💬 💬 |
| 14 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 15 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 16 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 17 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 18 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL1A 1件: IL1A 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 19 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 20 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 21 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 22 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 23 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL6R 1件: IL6R 💬 |
Tocilizumab Tocilizumab 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬 |
| 24 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1A 2件: IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 25 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 26 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
| 27 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL6R 1件: IL6R 💬 |
Tocilizumab Tocilizumab 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬 |
| 28 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 29 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 30 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IL6R 1件: IL6R 💬 |
Tocilizumab Tocilizumab 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬 |
| 31 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
IL1A 2件: IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 32 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 33 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
| 34 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Colchicine Colchicine 💬 |
Colchicine | 002 7件: 2 , 42, 46, 56, 93, 210, 266 💬 💬 |
| 35 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
IL1A 2件: IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 36 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 37 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1A 2件: IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 38 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 39 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
| 40 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL6R 1件: IL6R 💬 |
Tocilizumab Tocilizumab 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬 |
| 41 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 42 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 43 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IL6R 1件: IL6R 💬 |
Tocilizumab Tocilizumab 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬 |
| 44 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 45 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 46 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL1R1 1件: IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
| 47 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL6R 1件: IL6R 💬 |
Tocilizumab Tocilizumab 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬 |
| 48 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
| 49 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Colchicine Colchicine 💬 |
Colchicine | 002 7件: 2 , 42, 46, 56, 93, 210, 266 💬 💬 |
| 50 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 51 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 52 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL1A 2件: IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 53 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 54 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 55 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 56 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
IL1R1 1件: IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
| 57 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
IL1A 2件: IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 58 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 59 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL6R 1件: IL6R 💬 |
Tocilizumab Tocilizumab 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬 |
| 60 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 61 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 62 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
IL1A 2件: IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 63 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 64 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 65 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 66 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 67 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 68 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1A 2件: IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 69 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 70 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1R1 1件: IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
| 71 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL1A 2件: IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 72 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 73 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1A 2件: IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 74 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 75 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 76 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 77 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1R1 1件: IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
| 78 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 79 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 80 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL1A 2件: IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 81 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 82 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL6R 1件: IL6R 💬 |
Tocilizumab Tocilizumab 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬 |
| 83 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1A 2件: IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 84 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 85 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1R1 1件: IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
| 86 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Colchicine Colchicine 💬 |
Colchicine | 002 7件: 2 , 42, 46, 56, 93, 210, 266 💬 💬 |
| 87 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 88 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 89 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1R1 1件: IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
| 90 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Colchicine Colchicine 💬 |
Colchicine | 002 7件: 2 , 42, 46, 56, 93, 210, 266 💬 💬 |
| 91 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6R 1件: IL6R 💬 |
Tocilizumab Tocilizumab 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬 |
| 92 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL1A 2件: IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 93 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 94 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Colchicine Colchicine 💬 |
Colchicine | 002 7件: 2 , 42, 46, 56, 93, 210, 266 💬 💬 |
| 95 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL1A 2件: IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 96 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 97 | Phagosome 💬 13 genes, 10 drugs (DrugBank) and 21 diseases |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Colchicine Colchicine 💬 |
Colchicine | 002 7件: 2 , 42, 46, 56, 93, 210, 266 💬 💬 |
| 98 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6R 1件: IL6R 💬 |
Tocilizumab Tocilizumab 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬 |
| 99 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL1A 2件: IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 100 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 101 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Colchicine Colchicine 💬 |
Colchicine | 002 7件: 2 , 42, 46, 56, 93, 210, 266 💬 💬 |
| 102 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
IL1R2 1件: IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
| 103 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL1A 2件: IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 104 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 105 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 106 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 107 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TUBB 9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬 |
Colchicine Colchicine 💬 |
Colchicine | 002 7件: 2 , 42, 46, 56, 93, 210, 266 💬 💬 |
| 108 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 109 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 110 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1R1 1件: IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
| 111 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 112 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 113 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1R1 1件: IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
| 114 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL6R 1件: IL6R 💬 |
Tocilizumab Tocilizumab 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬 |
| 115 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 116 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 117 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 118 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 119 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
IL1R2 1件: IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
| 120 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL1A 2件: IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 121 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 122 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
IL1A 2件: IL1A, IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
| 123 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 124 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
IL6R 1件: IL6R 💬 |
Tocilizumab Tocilizumab 💬 |
Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬 |
| 125 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
| 126 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |