Target Gene/Pathway Pathway / Gene
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Showing 1 to 10 of 74 entries
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 1 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
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Metformin Metformin 💬Adipocytokine signaling pathway
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 2 ... 1. Adipocytokine signaling pathway
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| 2 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
VEGFA 1件: VEGFA 💬AGE-RAGE signaling pathway in diabetic complications
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Ranibizumab Ranibizumab 💬AGE-RAGE signaling pathway in diabetic complications
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬
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| 3 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
ADH1A 3件: ADH1A, ADH1B, ADH1C 💬
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Fomepizole Fomepizole 💬Alcoholic liver disease
| Fomepizole | 301 1件: 301 💬3. Alcoholic liver disease
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| 4 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
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Metformin Metformin 💬Alcoholic liver disease
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 2 ... 4. Alcoholic liver disease
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| 5 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
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Metformin Metformin 💬AMPK signaling pathway
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 2 ... 5. AMPK signaling pathway
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| 6 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
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Metformin Metformin 💬Apelin signaling pathway
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 2 ... 6. Apelin signaling pathway
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| 7 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬
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Metformin Metformin 💬Autophagy - animal
| Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 2 ... 7. Autophagy - animal
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| 8 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
VEGFA 1件: VEGFA 💬Bladder cancer
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Ranibizumab Ranibizumab 💬Bladder cancer
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬
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| 9 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
VEGFA 1件: VEGFA 💬Calcium signaling pathway
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Ranibizumab Ranibizumab 💬Calcium signaling pathway
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬
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| 10 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PDE5A 1件: PDE5A 💬cGMP-PKG signaling pathway
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Sildenafil Sildenafil 💬cGMP-PKG signaling pathway
| Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬10. cGMP-PKG signaling pathway
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