Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
2 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
PML 2件: PML, RARA 💬 |
Tretinoin Tretinoin 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 💬 |
3 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
4 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
ADORA2B 1件: ADORA2B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 1件: 63 💬 💬 |
5 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
PDE2A 1件: PDE2A 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 1件: 63 💬 💬 |
6 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
CD40LG 1件: CD40LG 💬 |
Toralizumab Toralizumab 💬 |
Toralizumab | 063 1件: 63 💬 💬 |
7 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
8 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
9 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
PSMB5 1件: PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
10 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
11 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
HMGCR 1件: HMGCR 💬 |
Atorvastatin Atorvastatin 💬 |
Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 💬 |
12 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
13 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
14 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
15 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
PSMB5 1件: PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
16 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
17 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
PDE3B 1件: PDE3B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 1件: 63 💬 💬 |
18 | Arrhythmogenic right ventricular cardiomyopathy 💬 11 genes, 24 drugs (DrugBank) and 28 diseases |
ITGA4 1件: ITGA4 💬 |
Natalizumab Natalizumab 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 💬 |
19 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
CD40LG 1件: CD40LG 💬 |
Toralizumab Toralizumab 💬 |
Toralizumab | 063 1件: 63 💬 💬 |
20 | Autoimmune thyroid disease 💬 22 genes, 15 drugs (DrugBank) and 35 diseases |
CD40LG 1件: CD40LG 💬 |
Toralizumab Toralizumab 💬 |
Toralizumab | 063 1件: 63 💬 💬 |
21 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
22 | Autophagy - other 💬 1 gene, 3 drugs (DrugBank) and 41 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
23 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
24 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
BTK 1件: BTK 💬 |
Orelabrutinib Orelabrutinib 💬 |
Orelabrutinib | 013 4件: 13, 49, 61, 63 💬 💬 |
25 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
BTK 1件: BTK 💬 |
Zanubrutinib Zanubrutinib 💬 |
Zanubrutinib | 013 5件: 13, 63, 222, 300, 331 💬 💬 |
26 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
27 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
HMGCR 1件: HMGCR 💬 |
Atorvastatin Atorvastatin 💬 |
Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 💬 |
28 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
ESR1 2件: ESR1, PGR 💬 |
Danazol Danazol 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 💬 |
29 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
30 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
31 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADORA2B 4件: ADORA2B, PDE1A, PDE1B, PDE1C 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 1件: 63 💬 💬 |
32 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CD38 1件: CD38 💬 |
Daratumumab Daratumumab 💬 |
Daratumumab | 013 5件: 13, 28, 48, 49, 63 💬 💬 |
33 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CD38 1件: CD38 💬 |
Mezagitamab Mezagitamab 💬 |
Mezagitamab | 063 2件: 63, 66 💬 💬 |
34 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CYSLTR1 1件: CYSLTR1 💬 |
Montelukast Montelukast 💬 |
Montelukast | 006 8件: 6 , 13, 46, 61, 63, 85, 98, 228 💬 💬 |
35 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
36 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA1 8件: ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 1件: 63 💬 💬 |
37 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CD40LG 1件: CD40LG 💬 |
Toralizumab Toralizumab 💬 |
Toralizumab | 063 1件: 63 💬 💬 |
38 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
ITGA4 1件: ITGA4 💬 |
Natalizumab Natalizumab 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 💬 |
39 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
40 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
41 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
42 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADORA1 4件: ADORA1, PDE2A, PDE3A, PDE3B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 1件: 63 💬 💬 |
43 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
44 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
AR 3件: AR, ESR1, PGR 💬 |
Danazol Danazol 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 💬 |
45 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
46 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
47 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
Lansoprazole Lansoprazole 💬 |
Lansoprazole | 063 7件: 63, 71, 85, 98, 166, 222, 299 💬 💬 |
48 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 35 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
Vonoprazan Vonoprazan 💬 |
Vonoprazan | 063 2件: 63, 98 💬 💬 |
49 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
50 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
PDE8A 2件: PDE8A, PDE8B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 1件: 63 💬 💬 |
51 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
PDE11A 3件: PDE11A, PDE8A, PDE8B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 1件: 63 💬 💬 |
52 | Cysteine and methionine metabolism 💬 3 genes, 1 drug (DrugBank) and 3 diseases |
DNMT1 3件: DNMT1, DNMT3A, DNMT3B 💬 |
Decitabine Decitabine 💬 |
Decitabine | 013 3件: 13, 60, 63 💬 💬 |
53 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CD40LG 1件: CD40LG 💬 |
Toralizumab Toralizumab 💬 |
Toralizumab | 063 1件: 63 💬 💬 |
54 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
MPL 1件: MPL 💬 |
Avatrombopag Avatrombopag 💬 |
Avatrombopag | 060 2件: 60, 63 💬 💬 |
55 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
MPL 1件: MPL 💬 |
Romiplostim Romiplostim 💬 |
Romiplostim | 060 4件: 60, 63, 64, 65 💬 💬 |
56 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNFRSF13C 1件: TNFRSF13C 💬 |
Ianalumab Ianalumab 💬 |
Ianalumab | 035 7件: 35, 46, 49, 53, 61, 63, 95 💬 💬 |
57 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNFSF13B 1件: TNFSF13B 💬 |
Belimumab Belimumab 💬 |
Belimumab | 011 13件: 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300 💬 💬 |
58 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
59 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
ITGA4 1件: ITGA4 💬 |
Natalizumab Natalizumab 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 💬 |
60 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
PPP3CA 3件: PPP3CA, PPP3CB, PPP3CC 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
61 | ECM-receptor interaction 💬 6 genes, 9 drugs (DrugBank) and 15 diseases |
ITGA4 1件: ITGA4 💬 |
Natalizumab Natalizumab 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 💬 |
62 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
63 | Endocrine and other factor-regulated calcium reabsorption 💬 8 genes, 27 drugs (DrugBank) and 55 diseases |
ESR1 1件: ESR1 💬 |
Danazol Danazol 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 💬 |
64 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
ESR1 1件: ESR1 💬 |
Danazol Danazol 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 💬 |
65 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
66 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
PML 1件: PML 💬 |
Tretinoin Tretinoin 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 💬 |
67 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
BTK 1件: BTK 💬 |
Orelabrutinib Orelabrutinib 💬 |
Orelabrutinib | 013 4件: 13, 49, 61, 63 💬 💬 |
68 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
BTK 1件: BTK 💬 |
Zanubrutinib Zanubrutinib 💬 |
Zanubrutinib | 013 5件: 13, 63, 222, 300, 331 💬 💬 |
69 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
70 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
ESR1 2件: ESR1, PGR 💬 |
Danazol Danazol 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 💬 |
71 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
RARA 1件: RARA 💬 |
Tretinoin Tretinoin 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 💬 |
72 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
BTK 1件: BTK 💬 |
Orelabrutinib Orelabrutinib 💬 |
Orelabrutinib | 013 4件: 13, 49, 61, 63 💬 💬 |
73 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
BTK 1件: BTK 💬 |
Zanubrutinib Zanubrutinib 💬 |
Zanubrutinib | 013 5件: 13, 63, 222, 300, 331 💬 💬 |
74 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
ITGA4 1件: ITGA4 💬 |
Natalizumab Natalizumab 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 💬 |
75 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
Lansoprazole Lansoprazole 💬 |
Lansoprazole | 063 7件: 63, 71, 85, 98, 166, 222, 299 💬 💬 |
76 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
Vonoprazan Vonoprazan 💬 |
Vonoprazan | 063 2件: 63, 98 💬 💬 |
77 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
78 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
RARB 1件: RARB 💬 |
Tretinoin Tretinoin 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 💬 |
79 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
80 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PDE3B 1件: PDE3B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 1件: 63 💬 💬 |
81 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
82 | Glutamatergic synapse 💬 23 genes, 27 drugs (DrugBank) and 83 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
83 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
84 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
CD38 1件: CD38 💬 |
Daratumumab Daratumumab 💬 |
Daratumumab | 013 5件: 13, 28, 48, 49, 63 💬 💬 |
85 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
CD38 1件: CD38 💬 |
Mezagitamab Mezagitamab 💬 |
Mezagitamab | 063 2件: 63, 66 💬 💬 |
86 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
ITGA4 1件: ITGA4 💬 |
Natalizumab Natalizumab 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 💬 |
87 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
MS4A1 1件: MS4A1 💬 |
Rituximab Rituximab 💬 |
Rituximab | 011 48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬 💬 |
88 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
89 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
90 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
PML 1件: PML 💬 |
Tretinoin Tretinoin 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 💬 |
91 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
92 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
93 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
94 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
95 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
96 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
ITGA4 1件: ITGA4 💬 |
Natalizumab Natalizumab 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 💬 |
97 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
98 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
99 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TNFRSF13C 1件: TNFRSF13C 💬 |
Ianalumab Ianalumab 💬 |
Ianalumab | 035 7件: 35, 46, 49, 53, 61, 63, 95 💬 💬 |
100 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
101 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
PSMB5 1件: PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
102 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
ITGA4 1件: ITGA4 💬 |
Natalizumab Natalizumab 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 💬 |
103 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
PML 1件: PML 💬 |
Tretinoin Tretinoin 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 💬 |
104 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
105 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
106 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PDE3B 1件: PDE3B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 1件: 63 💬 💬 |
107 | Intestinal immune network for IgA production 💬 16 genes, 27 drugs (DrugBank) and 47 diseases |
CD40LG 1件: CD40LG 💬 |
Toralizumab Toralizumab 💬 |
Toralizumab | 063 1件: 63 💬 💬 |
108 | Intestinal immune network for IgA production 💬 16 genes, 27 drugs (DrugBank) and 47 diseases |
ITGA4 1件: ITGA4 💬 |
Natalizumab Natalizumab 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 💬 |
109 | Intestinal immune network for IgA production 💬 16 genes, 27 drugs (DrugBank) and 47 diseases |
TNFRSF13C 1件: TNFRSF13C 💬 |
Ianalumab Ianalumab 💬 |
Ianalumab | 035 7件: 35, 46, 49, 53, 61, 63, 95 💬 💬 |
110 | Intestinal immune network for IgA production 💬 16 genes, 27 drugs (DrugBank) and 47 diseases |
TNFSF13B 1件: TNFSF13B 💬 |
Belimumab Belimumab 💬 |
Belimumab | 011 13件: 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300 💬 💬 |
111 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
MPL 1件: MPL 💬 |
Avatrombopag Avatrombopag 💬 |
Avatrombopag | 060 2件: 60, 63 💬 💬 |
112 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
MPL 1件: MPL 💬 |
Romiplostim Romiplostim 💬 |
Romiplostim | 060 4件: 60, 63, 64, 65 💬 💬 |
113 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
114 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
115 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
116 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
ITGA4 1件: ITGA4 💬 |
Natalizumab Natalizumab 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 💬 |
117 | Leukocyte transendothelial migration 💬 13 genes, 14 drugs (DrugBank) and 30 diseases |
ITGA4 1件: ITGA4 💬 |
Natalizumab Natalizumab 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 💬 |
118 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
CD40LG 1件: CD40LG 💬 |
Toralizumab Toralizumab 💬 |
Toralizumab | 063 1件: 63 💬 💬 |
119 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
120 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
121 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
122 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
123 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
CD40LG 1件: CD40LG 💬 |
Toralizumab Toralizumab 💬 |
Toralizumab | 063 1件: 63 💬 💬 |
124 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
125 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
Lansoprazole Lansoprazole 💬 |
Lansoprazole | 063 7件: 63, 71, 85, 98, 166, 222, 299 💬 💬 |
126 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
Vonoprazan Vonoprazan 💬 |
Vonoprazan | 063 2件: 63, 98 💬 💬 |
127 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CD38 1件: CD38 💬 |
Daratumumab Daratumumab 💬 |
Daratumumab | 013 5件: 13, 28, 48, 49, 63 💬 💬 |
128 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
CD38 1件: CD38 💬 |
Mezagitamab Mezagitamab 💬 |
Mezagitamab | 063 2件: 63, 66 💬 💬 |
129 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
DNMT1 3件: DNMT1, DNMT3A, DNMT3B 💬 |
Decitabine Decitabine 💬 |
Decitabine | 013 3件: 13, 60, 63 💬 💬 |
130 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR 1件: HMGCR 💬 |
Atorvastatin Atorvastatin 💬 |
Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 💬 |
131 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE10A 16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 1件: 63 💬 💬 |
132 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
DNMT1 3件: DNMT1, DNMT3A, DNMT3B 💬 |
Decitabine Decitabine 💬 |
Decitabine | 013 3件: 13, 60, 63 💬 💬 |
133 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
134 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
ADORA1 17件: ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 1件: 63 💬 💬 |
135 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
136 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
137 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADORA1 2件: ADORA1, ADORA2B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 1件: 63 💬 💬 |
138 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CYSLTR1 1件: CYSLTR1 💬 |
Montelukast Montelukast 💬 |
Montelukast | 006 8件: 6 , 13, 46, 61, 63, 85, 98, 228 💬 💬 |
139 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 1件: NR3C1 💬 |
Dexamethasone Dexamethasone 💬 |
Dexamethasone | 013 22件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 💬 |
140 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 1件: NR3C1 💬 |
Methylprednisolone Methylprednisolone 💬 |
Methylprednisolone | 002 46件: 2 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 💬 |
141 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 1件: NR3C1 💬 |
Prednisolone Prednisolone 💬 |
Prednisolone | 003 42件: 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 💬 |
142 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 1件: NR3C1 💬 |
Prednisone Prednisone 💬 |
Prednisone | 002 45件: 2 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬 💬 |
143 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
144 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
BTK 1件: BTK 💬 |
Orelabrutinib Orelabrutinib 💬 |
Orelabrutinib | 013 4件: 13, 49, 61, 63 💬 💬 |
145 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
BTK 1件: BTK 💬 |
Zanubrutinib Zanubrutinib 💬 |
Zanubrutinib | 013 5件: 13, 63, 222, 300, 331 💬 💬 |
146 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
CD40LG 1件: CD40LG 💬 |
Toralizumab Toralizumab 💬 |
Toralizumab | 063 1件: 63 💬 💬 |
147 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNFRSF13C 1件: TNFRSF13C 💬 |
Ianalumab Ianalumab 💬 |
Ianalumab | 035 7件: 35, 46, 49, 53, 61, 63, 95 💬 💬 |
148 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNFSF13B 1件: TNFSF13B 💬 |
Belimumab Belimumab 💬 |
Belimumab | 011 13件: 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300 💬 💬 |
149 | Nicotinate and nicotinamide metabolism 💬 1 gene, 3 drugs (DrugBank) and 8 diseases |
CD38 1件: CD38 💬 |
Daratumumab Daratumumab 💬 |
Daratumumab | 013 5件: 13, 28, 48, 49, 63 💬 💬 |
150 | Nicotinate and nicotinamide metabolism 💬 1 gene, 3 drugs (DrugBank) and 8 diseases |
CD38 1件: CD38 💬 |
Mezagitamab Mezagitamab 💬 |
Mezagitamab | 063 2件: 63, 66 💬 💬 |
151 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
RARB 1件: RARB 💬 |
Tretinoin Tretinoin 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 💬 |
152 | Olfactory transduction 💬 4 genes, 5 drugs (DrugBank) and 13 diseases |
PDE1A 4件: PDE1A, PDE1B, PDE1C, PDE2A 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 1件: 63 💬 💬 |
153 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
AR 2件: AR, PGR 💬 |
Danazol Danazol 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 💬 |
154 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
155 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
BTK 1件: BTK 💬 |
Orelabrutinib Orelabrutinib 💬 |
Orelabrutinib | 013 4件: 13, 49, 61, 63 💬 💬 |
156 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
BTK 1件: BTK 💬 |
Zanubrutinib Zanubrutinib 💬 |
Zanubrutinib | 013 5件: 13, 63, 222, 300, 331 💬 💬 |
157 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
158 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 25 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
Lansoprazole Lansoprazole 💬 |
Lansoprazole | 063 7件: 63, 71, 85, 98, 166, 222, 299 💬 💬 |
159 | Oxidative phosphorylation 💬 2 genes, 7 drugs (DrugBank) and 25 diseases |
ATP4A 2件: ATP4A, ATP4B 💬 |
Vonoprazan Vonoprazan 💬 |
Vonoprazan | 063 2件: 63, 98 💬 💬 |
160 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
CD38 1件: CD38 💬 |
Daratumumab Daratumumab 💬 |
Daratumumab | 013 5件: 13, 28, 48, 49, 63 💬 💬 |
161 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
CD38 1件: CD38 💬 |
Mezagitamab Mezagitamab 💬 |
Mezagitamab | 063 2件: 63, 66 💬 💬 |
162 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
163 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
164 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CD38 1件: CD38 💬 |
Daratumumab Daratumumab 💬 |
Daratumumab | 013 5件: 13, 28, 48, 49, 63 💬 💬 |
165 | Pancreatic secretion 💬 13 genes, 35 drugs (DrugBank) and 36 diseases |
CD38 1件: CD38 💬 |
Mezagitamab Mezagitamab 💬 |
Mezagitamab | 063 2件: 63, 66 💬 💬 |
166 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 1件: 63 💬 💬 |
167 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
PSMB5 1件: PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
168 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
AR 2件: AR, ESR1 💬 |
Danazol Danazol 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 💬 |
169 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
170 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PML 3件: PML, RARA, RARB 💬 |
Tretinoin Tretinoin 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 💬 |
171 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
172 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
173 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
PSMB5 1件: PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
174 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
175 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
176 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
177 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
ITGA4 1件: ITGA4 💬 |
Natalizumab Natalizumab 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 💬 |
178 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
179 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
BTK 1件: BTK 💬 |
Orelabrutinib Orelabrutinib 💬 |
Orelabrutinib | 013 4件: 13, 49, 61, 63 💬 💬 |
180 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
BTK 1件: BTK 💬 |
Zanubrutinib Zanubrutinib 💬 |
Zanubrutinib | 013 5件: 13, 63, 222, 300, 331 💬 💬 |
181 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
BTK 1件: BTK 💬 |
Orelabrutinib Orelabrutinib 💬 |
Orelabrutinib | 013 4件: 13, 49, 61, 63 💬 💬 |
182 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
BTK 1件: BTK 💬 |
Zanubrutinib Zanubrutinib 💬 |
Zanubrutinib | 013 5件: 13, 63, 222, 300, 331 💬 💬 |
183 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
CD40LG 1件: CD40LG 💬 |
Toralizumab Toralizumab 💬 |
Toralizumab | 063 1件: 63 💬 💬 |
184 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
TNFRSF13C 1件: TNFRSF13C 💬 |
Ianalumab Ianalumab 💬 |
Ianalumab | 035 7件: 35, 46, 49, 53, 61, 63, 95 💬 💬 |
185 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
186 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
PSMB5 1件: PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
187 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PDE3B 1件: PDE3B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 1件: 63 💬 💬 |
188 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PGR 1件: PGR 💬 |
Danazol Danazol 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 💬 |
189 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
ESR1 1件: ESR1 💬 |
Danazol Danazol 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 💬 |
190 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
AR 1件: AR 💬 |
Danazol Danazol 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 💬 |
191 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
192 | Proteasome 💬 2 genes, 5 drugs (DrugBank) and 20 diseases |
PSMB5 1件: PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
193 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
ESR1 1件: ESR1 💬 |
Danazol Danazol 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 💬 |
194 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
195 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE10A 16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 1件: 63 💬 💬 |
196 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
ADORA2B 1件: ADORA2B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 1件: 63 💬 💬 |
197 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
ITGA4 1件: ITGA4 💬 |
Natalizumab Natalizumab 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 💬 |
198 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
ADORA1 2件: ADORA1, PDE3B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 1件: 63 💬 💬 |
199 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
ADORA1 6件: ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 1件: 63 💬 💬 |
200 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
201 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNFSF13B 1件: TNFSF13B 💬 |
Belimumab Belimumab 💬 |
Belimumab | 011 13件: 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300 💬 💬 |
202 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
CD38 1件: CD38 💬 |
Daratumumab Daratumumab 💬 |
Daratumumab | 013 5件: 13, 28, 48, 49, 63 💬 💬 |
203 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
CD38 1件: CD38 💬 |
Mezagitamab Mezagitamab 💬 |
Mezagitamab | 063 2件: 63, 66 💬 💬 |
204 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
205 | Small cell lung cancer 💬 14 genes, 39 drugs (DrugBank) and 59 diseases |
RARB 1件: RARB 💬 |
Tretinoin Tretinoin 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 💬 |
206 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
ADORA1 1件: ADORA1 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 1件: 63 💬 💬 |
207 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
208 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
PSMB5 1件: PSMB5 💬 |
Bortezomib Bortezomib 💬 |
Bortezomib | 011 17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬 💬 |
209 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
CD40LG 1件: CD40LG 💬 |
Toralizumab Toralizumab 💬 |
Toralizumab | 063 1件: 63 💬 💬 |
210 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
CD40LG 1件: CD40LG 💬 |
Toralizumab Toralizumab 💬 |
Toralizumab | 063 1件: 63 💬 💬 |
211 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
212 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
PDE1A 3件: PDE1A, PDE1B, PDE1C 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 1件: 63 💬 💬 |
213 | Terpenoid backbone biosynthesis 💬 4 genes, 12 drugs (DrugBank) and 53 diseases |
HMGCR 1件: HMGCR 💬 |
Atorvastatin Atorvastatin 💬 |
Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 💬 |
214 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
215 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
216 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
217 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
RARA 1件: RARA 💬 |
Tretinoin Tretinoin 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 💬 |
218 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
219 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
ESR1 1件: ESR1 💬 |
Danazol Danazol 💬 |
Danazol | 060 5件: 60, 63, 64, 65, 285 💬 💬 |
220 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
221 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
CD40LG 1件: CD40LG 💬 |
Toralizumab Toralizumab 💬 |
Toralizumab | 063 1件: 63 💬 💬 |
222 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
PML 2件: PML, RARA 💬 |
Tretinoin Tretinoin 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 💬 |
223 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
224 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
225 | Ubiquitin mediated proteolysis 💬 2 genes, 2 drugs (DrugBank) and 11 diseases |
PML 1件: PML 💬 |
Tretinoin Tretinoin 💬 |
Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬 💬 |
226 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
ADORA2B 1件: ADORA2B 💬 |
Aminophylline Aminophylline 💬 |
Aminophylline | 063 1件: 63 💬 💬 |
227 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
228 | Viral myocarditis 💬 10 genes, 19 drugs (DrugBank) and 46 diseases |
CD40LG 1件: CD40LG 💬 |
Toralizumab Toralizumab 💬 |
Toralizumab | 063 1件: 63 💬 💬 |
229 | Wnt signaling pathway 💬 9 genes, 9 drugs (DrugBank) and 61 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
Cyclosporine Cyclosporine 💬 |
Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬 |
230 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
ITGA4 1件: ITGA4 💬 |
Natalizumab Natalizumab 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 💬 |