Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Adherens junction 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
2 Alcoholism 💬
 1件: ADORA2A 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
3 Alcoholism 💬
 1件: ADORA2A 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
4 Alcoholism 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
5 Aldosterone synthesis and secretion 💬
 1件: MC2R 💬 Cosyntropin 💬 Tetracosactide 5件: 78, 83, 113, 145, 222 💬 💬
6 Aldosterone synthesis and secretion 💬
 1件: PDE2A 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
7 Aldosterone synthesis and secretion 💬
 1件: PDE2A 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
8 Alzheimer disease 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
9 Alzheimer disease 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
10 Amphetamine addiction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
11 AMPK signaling pathway 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
12 AMPK signaling pathway 💬
 1件: PPARG 💬 Pioglitazone 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬
13 Amyotrophic lateral sclerosis 💬
 6件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
14 Apelin signaling pathway 💬
 1件: PDE3B 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
15 Apelin signaling pathway 💬
 1件: PDE3B 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
16 Arachidonic acid metabolism 💬
 2件: PTGS1, PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
17 Autophagy - animal 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
18 Breast cancer 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
19 C-type lectin receptor signaling pathway 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
20 Calcium signaling pathway 💬
 2件: ADORA2A, PDE1B 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
21 Calcium signaling pathway 💬
 2件: ADORA2A, PDE1B 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
22 Calcium signaling pathway 💬
 4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
23 cAMP signaling pathway 💬
 8件: ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
24 cAMP signaling pathway 💬
 8件: ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
25 cAMP signaling pathway 💬
 1件: GHSR 💬 Macimorelin 💬 Macimorelin 1件: 78 💬 💬
26 cAMP signaling pathway 💬
 1件: GLP1R 💬 Exenatide 💬 Exenatide 6件:  6 , 17, 72, 78, 193, 233 💬 💬
27 cAMP signaling pathway 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
28 cAMP signaling pathway 💬
 1件: MC2R 💬 Cosyntropin 💬 Tetracosactide 5件: 78, 83, 113, 145, 222 💬 💬
29 cAMP signaling pathway 💬
 3件: SSTR1, SSTR2, SSTR5 💬 Somatostatin 💬 Somatostatin 2件: 67, 78 💬 💬
30 cGMP-PKG signaling pathway 💬
 5件: ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
31 cGMP-PKG signaling pathway 💬
 5件: ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
32 cGMP-PKG signaling pathway 💬
 3件: ADRA2A, ADRA2B, ADRA2C 💬 Clonidine 💬 Clonidine 4件:  6 , 65, 70, 78 💬 💬
33 Chemical carcinogenesis - DNA adducts 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
34 Chemical carcinogenesis - receptor activation 💬
 1件: AR 💬 Testosterone 💬 Testosterone 8件:  1 ,  2 ,  3 , 13, 60, 76, 78, 113 💬 💬
35 Cholinergic synapse 💬
 1件: ACHE 💬 Donepezil 💬 Donepezil 9件:  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬 💬
36 Circadian entrainment 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
37 Circadian entrainment 💬
 2件: MTNR1A, MTNR1B 💬 Melatonin 💬 Melatonin 12件:  6 ,  8 , 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬 💬
38 Cocaine addiction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
39 Cortisol synthesis and secretion 💬
 1件: MC2R 💬 Cosyntropin 💬 Tetracosactide 5件: 78, 83, 113, 145, 222 💬 💬
40 Cushing syndrome 💬
 1件: MC2R 💬 Cosyntropin 💬 Tetracosactide 5件: 78, 83, 113, 145, 222 💬 💬
41 Cytokine-cytokine receptor interaction 💬
 1件: GHR 💬 Lonapegsomatropin 💬 Lonapegsomatropin 1件: 78 💬 💬
42 Cytokine-cytokine receptor interaction 💬
 1件: GHR 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
43 Cytokine-cytokine receptor interaction 💬
 1件: GHR 💬 Pegvisomant 💬 Pegvisomant 2件: 78, 265 💬 💬
44 Cytokine-cytokine receptor interaction 💬
 1件: GHR 💬 Somapacitan 💬 Somapacitan 2件: 78, 195 💬 💬
45 Cytokine-cytokine receptor interaction 💬
 1件: GHR 💬 Somavaratan 💬 Somavaratan 1件: 78 💬 💬
46 Dopaminergic synapse 💬
 2件: GRIN2A, GRIN2B 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
47 EGFR tyrosine kinase inhibitor resistance 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
48 Endocrine resistance 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
49 Endocytosis 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
50 Estrogen signaling pathway 💬
 1件: OPRM1 💬 Tramadol 💬 Tramadol 5件: 46, 70, 78, 226, 271 💬 💬
51 Focal adhesion 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
52 FoxO signaling pathway 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
53 Gastric acid secretion 💬
 1件: SSTR2 💬 Somatostatin 💬 Somatostatin 2件: 67, 78 💬 💬
54 Glioma 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
55 Glucagon signaling pathway 💬
 1件: PDE3B 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
56 Glucagon signaling pathway 💬
 1件: PDE3B 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
57 Glutamatergic synapse 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
58 Glycerophospholipid metabolism 💬
 1件: ACHE 💬 Donepezil 💬 Donepezil 9件:  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬 💬
59 Growth hormone synthesis, secretion and action 💬
 1件: GHR 💬 Lonapegsomatropin 💬 Lonapegsomatropin 1件: 78 💬 💬
60 Growth hormone synthesis, secretion and action 💬
 1件: GHR 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
61 Growth hormone synthesis, secretion and action 💬
 1件: GHR 💬 Pegvisomant 💬 Pegvisomant 2件: 78, 265 💬 💬
62 Growth hormone synthesis, secretion and action 💬
 1件: GHR 💬 Somapacitan 💬 Somapacitan 2件: 78, 195 💬 💬
63 Growth hormone synthesis, secretion and action 💬
 1件: GHR 💬 Somavaratan 💬 Somavaratan 1件: 78 💬 💬
64 Growth hormone synthesis, secretion and action 💬
 1件: GHRHR 💬 Somatorelin 💬 Somatorelin 2件: 13, 78 💬 💬
65 Growth hormone synthesis, secretion and action 💬
 1件: GHRHR 💬 Tesamorelin 💬 Tesamorelin 2件: 78, 265 💬 💬
66 Growth hormone synthesis, secretion and action 💬
 1件: GHSR 💬 Macimorelin 💬 Macimorelin 1件: 78 💬 💬
67 Growth hormone synthesis, secretion and action 💬
 4件: SSTR1, SSTR2, SSTR3, SSTR5 💬 Somatostatin 💬 Somatostatin 2件: 67, 78 💬 💬
68 Hepatocellular carcinoma 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
69 HIF-1 signaling pathway 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
70 Human cytomegalovirus infection 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
71 Human papillomavirus infection 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
72 Huntington disease 💬
 2件: GRIN1, GRIN2B 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
73 Huntington disease 💬
 1件: PPARG 💬 Pioglitazone 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬
74 IL-17 signaling pathway 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
75 Insulin secretion 💬
 1件: GLP1R 💬 Exenatide 💬 Exenatide 6件:  6 , 17, 72, 78, 193, 233 💬 💬
76 Insulin signaling pathway 💬
 1件: PDE3B 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
77 Insulin signaling pathway 💬
 1件: PDE3B 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
78 JAK-STAT signaling pathway 💬
 1件: GHR 💬 Lonapegsomatropin 💬 Lonapegsomatropin 1件: 78 💬 💬
79 JAK-STAT signaling pathway 💬
 1件: GHR 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
80 JAK-STAT signaling pathway 💬
 1件: GHR 💬 Pegvisomant 💬 Pegvisomant 2件: 78, 265 💬 💬
81 JAK-STAT signaling pathway 💬
 1件: GHR 💬 Somapacitan 💬 Somapacitan 2件: 78, 195 💬 💬
82 JAK-STAT signaling pathway 💬
 1件: GHR 💬 Somavaratan 💬 Somavaratan 1件: 78 💬 💬
83 Kaposi sarcoma-associated herpesvirus infection 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
84 Leishmaniasis 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
85 Lipid and atherosclerosis 💬
 1件: PPARG 💬 Pioglitazone 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬
86 Long-term depression 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
87 Long-term potentiation 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
88 Longevity regulating pathway 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
89 Longevity regulating pathway 💬
 1件: PPARG 💬 Pioglitazone 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬
90 Longevity regulating pathway - multiple species 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
91 MAPK signaling pathway 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
92 Melanoma 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
93 Metabolic pathways 💬
 1件: CYP19A1 💬 Anastrozole 💬 Anastrozole 3件: 78, 86, 193 💬 💬
94 Metabolic pathways 💬
 9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
95 Metabolic pathways 💬
 9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
96 Metabolic pathways 💬
 2件: PTGS1, PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
97 MicroRNAs in cancer 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
98 Morphine addiction 💬
 9件: ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
99 Morphine addiction 💬
 9件: ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
100 Morphine addiction 💬
 1件: OPRM1 💬 Tramadol 💬 Tramadol 5件: 46, 70, 78, 226, 271 💬 💬
101 mTOR signaling pathway 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
102 Neuroactive ligand-receptor interaction 💬
 2件: ADORA1, ADORA2A 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
103 Neuroactive ligand-receptor interaction 💬
 2件: ADORA1, ADORA2A 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
104 Neuroactive ligand-receptor interaction 💬
 3件: ADRA2A, ADRA2B, ADRA2C 💬 Clonidine 💬 Clonidine 4件:  6 , 65, 70, 78 💬 💬
105 Neuroactive ligand-receptor interaction 💬
 1件: GHR 💬 Lonapegsomatropin 💬 Lonapegsomatropin 1件: 78 💬 💬
106 Neuroactive ligand-receptor interaction 💬
 1件: GHR 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
107 Neuroactive ligand-receptor interaction 💬
 1件: GHR 💬 Pegvisomant 💬 Pegvisomant 2件: 78, 265 💬 💬
108 Neuroactive ligand-receptor interaction 💬
 1件: GHR 💬 Somapacitan 💬 Somapacitan 2件: 78, 195 💬 💬
109 Neuroactive ligand-receptor interaction 💬
 1件: GHR 💬 Somavaratan 💬 Somavaratan 1件: 78 💬 💬
110 Neuroactive ligand-receptor interaction 💬
 1件: GHRHR 💬 Somatorelin 💬 Somatorelin 2件: 13, 78 💬 💬
111 Neuroactive ligand-receptor interaction 💬
 1件: GHRHR 💬 Tesamorelin 💬 Tesamorelin 2件: 78, 265 💬 💬
112 Neuroactive ligand-receptor interaction 💬
 1件: GHSR 💬 Macimorelin 💬 Macimorelin 1件: 78 💬 💬
113 Neuroactive ligand-receptor interaction 💬
 1件: GLP1R 💬 Exenatide 💬 Exenatide 6件:  6 , 17, 72, 78, 193, 233 💬 💬
114 Neuroactive ligand-receptor interaction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
115 Neuroactive ligand-receptor interaction 💬
 1件: MC2R 💬 Cosyntropin 💬 Tetracosactide 5件: 78, 83, 113, 145, 222 💬 💬
116 Neuroactive ligand-receptor interaction 💬
 2件: MTNR1A, MTNR1B 💬 Melatonin 💬 Melatonin 12件:  6 ,  8 , 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬 💬
117 Neuroactive ligand-receptor interaction 💬
 1件: NR3C1 💬 Hydrocortisone 💬 Hydrocortisone 10件:  6 , 41, 46, 53, 75, 78, 81, 83, 97, 299 💬 💬
118 Neuroactive ligand-receptor interaction 💬
 1件: OPRM1 💬 Tramadol 💬 Tramadol 5件: 46, 70, 78, 226, 271 💬 💬
119 Neuroactive ligand-receptor interaction 💬
 5件: SSTR1, SSTR2, SSTR3, SSTR4, SSTR5 💬 Somatostatin 💬 Somatostatin 2件: 67, 78 💬 💬
120 Neuroactive ligand-receptor interaction 💬
 2件: THRA, THRB 💬 Levothyroxine 💬 Levothyroxine 5件: 19, 49, 78, 80, 222 💬 💬
121 Neuroactive ligand-receptor interaction 💬
 2件: THRA, THRB 💬 Liothyronine 💬 Liothyronine 4件: 13, 78, 210, 212 💬 💬
122 Neuroactive ligand-receptor interaction 💬
 2件: THRA, THRB 💬 Tiratricol 💬 Tiratricol 2件: 78, 139 💬 💬
123 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
124 Nicotine addiction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
125 Non-alcoholic fatty liver disease 💬
 1件: PPARG 💬 Pioglitazone 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬
126 Olfactory transduction 💬
 2件: PDE1B, PDE2A 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
127 Olfactory transduction 💬
 2件: PDE1B, PDE2A 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
128 Oocyte meiosis 💬
 1件: AR 💬 Testosterone 💬 Testosterone 8件:  1 ,  2 ,  3 , 13, 60, 76, 78, 113 💬 💬
129 Oocyte meiosis 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
130 Osteoclast differentiation 💬
 1件: PPARG 💬 Pioglitazone 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬
131 Ovarian steroidogenesis 💬
 1件: CYP19A1 💬 Anastrozole 💬 Anastrozole 3件: 78, 86, 193 💬 💬
132 Ovarian steroidogenesis 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
133 Ovarian steroidogenesis 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
134 Oxytocin signaling pathway 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
135 Parathyroid hormone synthesis, secretion and action 💬
 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
136 Parathyroid hormone synthesis, secretion and action 💬
 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
137 Parkinson disease 💬
 1件: ADORA2A 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
138 Parkinson disease 💬
 1件: ADORA2A 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
139 Pathways in cancer 💬
 1件: AR 💬 Testosterone 💬 Testosterone 8件:  1 ,  2 ,  3 , 13, 60, 76, 78, 113 💬 💬
140 Pathways in cancer 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
141 Pathways in cancer 💬
 1件: PPARG 💬 Pioglitazone 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬
142 Pathways in cancer 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
143 Pathways of neurodegeneration - multiple diseases 💬
 6件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
144 Pathways of neurodegeneration - multiple diseases 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
145 PI3K-Akt signaling pathway 💬
 1件: GHR 💬 Lonapegsomatropin 💬 Lonapegsomatropin 1件: 78 💬 💬
146 PI3K-Akt signaling pathway 💬
 1件: GHR 💬 Pegvisomant 💬 Pegvisomant 2件: 78, 265 💬 💬
147 PI3K-Akt signaling pathway 💬
 1件: GHR 💬 Somapacitan 💬 Somapacitan 2件: 78, 195 💬 💬
148 PI3K-Akt signaling pathway 💬
 1件: GHR 💬 Somavaratan 💬 Somavaratan 1件: 78 💬 💬
149 PI3K-Akt signaling pathway 💬
 2件: GHR, IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
150 Platelet activation 💬
 1件: PTGS1 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
151 PPAR signaling pathway 💬
 1件: PPARG 💬 Pioglitazone 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬
152 Prion disease 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
153 Progesterone-mediated oocyte maturation 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
154 Progesterone-mediated oocyte maturation 💬
 1件: PDE3B 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
155 Progesterone-mediated oocyte maturation 💬
 1件: PDE3B 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
156 Prostate cancer 💬
 1件: AR 💬 Testosterone 💬 Testosterone 8件:  1 ,  2 ,  3 , 13, 60, 76, 78, 113 💬 💬
157 Prostate cancer 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
158 Proteoglycans in cancer 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
159 Purine metabolism 💬
 9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
160 Purine metabolism 💬
 9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
161 Rap1 signaling pathway 💬
 1件: ADORA2A 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
162 Rap1 signaling pathway 💬
 1件: ADORA2A 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
163 Rap1 signaling pathway 💬
 3件: GRIN1, GRIN2A, GRIN2B 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
164 Rap1 signaling pathway 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
165 Ras signaling pathway 💬
 3件: GRIN1, GRIN2A, GRIN2B 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
166 Ras signaling pathway 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
167 Regulation of lipolysis in adipocytes 💬
 2件: ADORA1, PDE3B 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
168 Regulation of lipolysis in adipocytes 💬
 2件: ADORA1, PDE3B 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
169 Regulation of lipolysis in adipocytes 💬
 2件: PTGS1, PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
170 Renin secretion 💬
 4件: ADORA1, PDE1B, PDE3A, PDE3B 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
171 Renin secretion 💬
 4件: ADORA1, PDE1B, PDE3A, PDE3B 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
172 Retrograde endocannabinoid signaling 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
173 Serotonergic synapse 💬
 2件: PTGS1, PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
174 Serotonergic synapse 💬
 1件: SLC6A4 💬 Amitriptyline 💬 Amitriptyline 4件: 78, 97, 226, 299 💬 💬
175 Serotonergic synapse 💬
 1件: SLC6A4 💬 Fluoxetine 💬 Fluoxetine 6件: 13, 17, 78, 86, 179, 206 💬 💬
176 Signaling pathways regulating pluripotency of stem cells 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
177 Small cell lung cancer 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
178 Sphingolipid signaling pathway 💬
 1件: ADORA1 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
179 Sphingolipid signaling pathway 💬
 1件: ADORA1 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
180 Spinocerebellar ataxia 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
181 Steroid hormone biosynthesis 💬
 1件: CYP19A1 💬 Anastrozole 💬 Anastrozole 3件: 78, 86, 193 💬 💬
182 Synaptic vesicle cycle 💬
 2件: SLC6A2, SLC6A4 💬 Amitriptyline 💬 Amitriptyline 4件: 78, 97, 226, 299 💬 💬
183 Synaptic vesicle cycle 💬
 1件: SLC6A4 💬 Fluoxetine 💬 Fluoxetine 6件: 13, 17, 78, 86, 179, 206 💬 💬
184 Systemic lupus erythematosus 💬
 2件: GRIN2A, GRIN2B 💬 Dextromethorphan 💬 Dextromethorphan 11件:  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 💬
185 Taste transduction 💬
 1件: PDE1B 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
186 Taste transduction 💬
 1件: PDE1B 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
187 Thermogenesis 💬
 1件: PPARG 💬 Pioglitazone 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬
188 Thyroid cancer 💬
 1件: PPARG 💬 Pioglitazone 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬
189 Thyroid hormone signaling pathway 💬
 2件: THRA, THRB 💬 Levothyroxine 💬 Levothyroxine 5件: 19, 49, 78, 80, 222 💬 💬
190 Thyroid hormone signaling pathway 💬
 2件: THRA, THRB 💬 Liothyronine 💬 Liothyronine 4件: 13, 78, 210, 212 💬 💬
191 Thyroid hormone signaling pathway 💬
 2件: THRA, THRB 💬 Tiratricol 💬 Tiratricol 2件: 78, 139 💬 💬
192 TNF signaling pathway 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
193 Transcriptional misregulation in cancer 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
194 Transcriptional misregulation in cancer 💬
 1件: PPARG 💬 Pioglitazone 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬
195 Vascular smooth muscle contraction 💬
 1件: ADORA2A 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
196 Vascular smooth muscle contraction 💬
 1件: ADORA2A 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬 💬
197 VEGF signaling pathway 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬

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